An evaluation of the relative roles of the unstirred water layer and receptor sink in limiting the in-vitro intestinal permeability of drug compounds of varying lipophilicity

Journal of Pharmacy and Pharmacology

Volumn 60, Issue 10, 2008, Pages 1311-1319

  Katneni, Kasiram ^a   Charman, Susan A ^a   Porter, Christopher J H ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BOVINE SERUM ALBUMIN; CINNARIZINE; DIAZEPAM; MANNITOL; OROSOMUCOID; POLYSORBATE 80;

ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG PENETRATION; DRUG SOLUBILITY; DRUG TRANSPORT; IN VITRO STUDY; INTESTINE ABSORPTION; LIPOPHILICITY; MALE; NONHUMAN; RAT; RECEPTOR SINK; SOLUBILIZATION; UNSTIRRED WATER LAYER;

EID: 52949093858     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.60.10.0007     Document Type: Article

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