Antiproliferative activity against human tumor cell lines and toxicity test on Mediterranean dietary plants

Food and Chemical Toxicology

Volumn 46, Issue 10, 2008, Pages 3325-3332

  Conforti, F ^a   Ioele, G ^a   Statti, G A ^a   Marrelli, M ^a   Ragno, G ^a   Menichini, F ^a  

^a UNIVERSITY OF CALABRIA   (Italy)

Author keywords

Acute toxicity; Antiproliferative activity; Bioluminescence test; Human cancer; Phenolic and flavonoid content; Phytosterols

Indexed keywords

CICHORIUM INTYBUS EXTRACT; CYNARA CARDUNCULUS EXTRACT; FLAVONOID; MENTHA AQUATICA EXTRACT; PHYTOSTEROL; PLANT EXTRACT; SULFANILAMIDE; UNCLASSIFIED DRUG;

AMELANOTIC MELANOMA; ARTICLE; BIOLUMINESCENCE; BREAST CANCER; CARDOON; CELL PROLIFERATION; CHICORY; CONTROLLED STUDY; FOOD COMPOSITION; HUMAN; HUMAN CELL; KIDNEY CARCINOMA; MEDITERRANEAN DIET; MENTHA; PROSTATE CANCER; TOXICITY TESTING; TUMOR CELL LINE; VIBRIO FISCHERI;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; ITALY; MEDITERRANEAN REGION; PLANT EXTRACTS; PLANTS, EDIBLE;

BACTERIA (MICROORGANISMS); CICHORIUM INTYBUS; CYNARA CARDUNCULUS; ECHIUM VULGARE; MALVA SYLVESTRIS; MENTHA AQUATICA; VIBRIO FISCHERI;

EID: 52949088607     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2008.08.004     Document Type: Article

References (64)

1. Areias F.M., Valentano P., Andrade P.B., Ferreres F., and Seabra R.M. Phenolic fingerprint of peppermint leaves. Food Chem. 73 (2001) 307-311
2. AZUR, 1997. Microtox Manual. Azur Environmental (formely Microbics Corporation), vol. 1-4. 2232 Rutherford Road, Carlsbad, CA.
3. Balunas M.J., and Kinghorn A.D. Drug discovery from medicinal plants. Life Sci. 78 (2005) 431-441
4. Bruneton J. Toxic Plants Dangerous to Humans and Animals (1999), Lavoisier Publishing, Paris p. 206
5. Butler M.S. The role of natural product chemistry in drug discovery. J. Nat. Prod. 67 (2004) 2141-2153
6. Chen C.C., Liu L.K., Hsu J.D., Huang H.P., Yang M.Y., and Wang C.J. Mulberry extract inhibits the development of atherosclerosis in cholesterol-fed rabbits. Food Chem. 91 (2005) 601-607
7. Chen P.N., Chu S.C., Chiou H.L., Kuo W.H., Chiang C.L., and Hsieh Y.S. Mulberry anthocyanins, cyaniding 3-rutinoside and cyaniding-3-glucoside, exhibited and inhibitory effect on the migration and invasion of a human lung cancer cell line. Cancer Lett. 235 (2006) 248-259
8. Conforti F., Loizzo M.R., Statti G., Houghton P.J., and Menichini F. Biological properties of different extracts of two Senecio species. Int. J. Food Sci. Nutr. 57 (2006) 1-8
9. Cotou E., Papathanassiou E., and Tsangaris C. Assessing the quality of marine coastal environments: comparison of scope for growth and microtox bioassay results of pollution gradient areas in eastern Mediterranean (Greece). Environ. Pollut. 119 (2002) 141-149
10. Cragg, G.M., Boyd, M.R., Cardellina I.I., J.H., Newman, D.J., Snader, K.M., McCloud, T.G., 1994. Ethnobotany and drug discovery: the experience of the US National Cancer Institute. In: Ethnobotany and Search for New Drugs.
11. Cragg G.M., and Newman D.J. A tale of two tumor targets: topoisomerase I and tubulin. The Wall and Wani contribution to cancer chemotherapy. J. Nat. Prod. 67 (2004) 232-244
12. Davere M., and Bahadir M. Biological monitoring of landfill leachates using plants and luminescent bacteria. Chemosphere 28 (1994) 261-271
13. El-Shazly A., Sargm T., Ateya A., Abdel Aziz A., El-Dahmy S., Witte L., and Wink K. Pyrrolizidine alkaloids from Echium setosum and Echium vulgare. J. Nat. Prod. 59 (1996) 310-313
14. Farre M., and Barcelo D. Toxicity testing of wastewater and sewage sludge by biosensors, bioassays and chemical analysis. Trends Anal. Chem. 22 (2003) 299-310
15. Ferdowsian H.R., and Barnard N.D. The role of diet in breast and prostate cancer survival. Ethn. Dis. 17 (2007) S218-S222
16. Frohne, D., Pfänder, H.J., 1997. Giftpflanzen. Ein Handbuch für Apotheker, Ärzte, Toxikologen und Biologen. Wissenschaftliche Verlagsgesellschaft mbH: Würzburg, pp. 306-307.
17. Fulladosa E., Murat J.C., Martinez M., and Villaescusa I. Effect of pH on arsenate and arsenite toxicity to luminescent bacteria (Vibrio fischeri). Arch. Environ. Contam. Toxicol. 46 (2004) 176-183
18. Fulladosa E., Murat J.C., Martìnez M., and Villaescusa I. Patterns of metals and arsenic poisoning in Vibrio fischeri bacteria. Chemosphere 60 (2005) 43-48
19. Gordaliza M., Garcia P.A., del Corral J.M., Castro M.A., and Gomez-Zurita M.A. Podophyllotoxin: distribution, sources, applications and new cytotoxic derivatives. Toxicon 44 (2004) 441-459
20. Guerra R. Ecotoxicological and chemical evaluation of phenolic compound in industrial effluents. Chemosphere 44 (2001) 1737-1747
21. Harborne J.B., and Williams C.A. Advances in flavonoid research since 1992. Phytochemistry 55 (2000) 481-504
22. Hoffmann C., and Christofi N. Testing the toxicity of influents to activated sludge plants with the Vibrio fischeri bioassay utilizing a sludge matrix. Environ. Toxicol. 16 (2001) 422-427
23. Imanaka H., Koide H., Shimizu K., Asai T., Kinouchi Shimizu N., Ishikado A., Makino T., and Oku N. Chemoprevention of tumor metastasis by liposomal beta-sitosterol intake. Biol. Pharm. Bull. 31 (2008) 400-404
24. Indap M.A., and Barkume M.S. Efficacies of plant phenolic compounds on sodium butyrate induced anti-tumour activity. Indian J. Exp. Biol. 41 (2003) 861-864
25. Inocencio C., Rivera D., Obòn M.C., Alcaraz F., and Barrena J.A. A systematic revision of Capparis section Capparis (Capparaceae). Ann. Missouri Bot. Gard. 93 (2006) 122-149
26. IRSA, 1995. Metodi analitici per le acque. Quad. Ist. Ric. Acque, 100, p. 342.
27. ISO 11348/1-2-3, 1998. Determination of the inhibitory effect of water samples on the light emission of Vibrio fischeri.
28. Jones W.P., Chin Y.W., and Kinghorn A.D. The role of pharmacognosy in modern medicine and pharmacy. Curr. Drug Targets 7 (2006) 247-264
29. Kampa M., Alexaki V.I., Notas G., Nifli A.P., Nistikaki A., Hatzoglou A., Bakogeorgou E., Kouimtzoglou E., Blekas G., Boskou D., Gravanis A., and Castanas E. Antiproliferative and apoptotic effects of selective phenolic acids on T47D human breast cancer cells: potential mechanisms of action. Breast Cancer Res. 6 (2004) 63-74
30. Karvelas M., Katsoyiannis A., and Samara C. Occurrence and fate of heavy metals in the wastewater treatment plant of Thessaloniki. Environ. Sci. Pollut. Res. Spec. 3 (2002) 194-195
31. Katsoyiannis A., and Samara C. Ecotoxicological evaluation of the wastewater treatment process of the sewage treatment plant of Thessaloniki, Greece. J. Hazard Mater. 141 (2007) 614-621
32. Koehn F.E., and Carter G.T. The evolving role of natural products in drug discovery. Nat. Rev. Drug Discov. 4 (2005) 206-220
33. Moghadasian M.H. Minireview. Pharmacological properties of plant sterols In vivo and in vitro observations. Life Sci. 67 (2000) 605-615
34. Miadokova E., Nadova S., Trebaticka M., Grolmus J., Kopaskova M., Rauko P., Mucaji P., and Grancai D. Research on biomodulatory effect of natural compounds. Neuro. Endocrinol. Lett. 27 (2006) 53-56
35. Nadova S., Miadokova E., Mucaji P., Grancai D., and Cipak L. Growth inhibitory effect of ethyl acetate-soluble fraction of Cynara cardunculus L. in leukemia cells involves cell cycle arrest, cytochrome c release and activation of caspases. Phytother. Res. 17 (2007) Aug Epub ahead of print
36. Newman D.J., Cragg G.M., and Snader K.M. Natural products as sources of new drugs over the period 1981-2002. J. Nat. Prod. 66 (2003) 1022-1037
37. Oberlies N.H., and Kroll D.J. Camptothecin and taxol: historic achievements in natural products research. J. Nat. Prod. 67 (2004) 129-135
38. Okouneva T., Hill B.T., Wilson L., and Jordan M.A. The effects of vinflunine, vinorelbine, and vinblastine on centromere dynamics. Mol. Cancer Ther. 2 (2003) 427-436
39. Park K., and Que Hee S. Effect of dust on the viability of Vibrio fischeri in the Microtox test. Ecotoxicol. Environ. Safe. 50 (2001) 189-195
40. Parkin D.M., Bray F., Ferlay J., and Pisani P. Estimating the world cancer burden: Globocan 2000. Int. J. Cancer 94 (2001) 153-156
41. Parvez S., Venkataraman C., and Mukherji S. A review on advantages of implementing luminescence inhibition test (Vibrio fischeri) for acute toxicity prediction of chemicals. Environ. Int. 32 (2006) 265-268
42. Pierce J.P., Natarajan L., Caan B.J., Parker B.A., Greenberg E.R., Flatt S.W., Rock C.L., Kealey S., Al-Delaimy W.K., Bardwell W.A., Carlson R.W., Emond J.A., Faerber S., Gold E.B., Hajek R.A., Hollenbach K., Jones L.A., Karanja N., Madlensky L., Marshall J., Newman V.A., Ritenbaugh C., Thomson C.A., Wasserman L., and Stefanick M.L. Influence of a diet very high in vegetables, fruit, and fiber and low in fat on prognosis following treatment for breast cancer: the Women's Healthy Eating and Living (WHEL) randomized trial. JAMA 18 (2007) 335-336
43. Pignatti, S., 1982. Flora d'Italia. (voll. 3) Edagricole.
44. Prior R.L. Fruits and vegetables in the prevention of cellular oxidative damage. Am. J. Clin. Nutr. 78 (2003) 570S-578S
45. Qian J.Y., Liu D., and Huang A.G. The efficiency of flavonoids in polar extracts of Lycium Chinese Mill fruits as free radical scavenger. Food Chem. 87 (2004) 283-288
46. Quettier-Deleu C., Gressier B., Vasseur J., Dine T., Brunet C., Luyckx M., Cazin M., Cazin J.C., Bailleul F., and Trotin F. Phenolic compounds and antioxidant activities of buckwheat hulls and flour. J. Ethnopharmacol. 72 (2000) 35-42
47. Ribò J.M., and Kaiser K.L. Photobacterium phosphoreum toxicity bioassay. Test procedures and applications. Environ. Toxicol. Water Qual. 2 (2006) 305-323
48. Rosenthal J. Curtain has fallen on hopes of legal bioprospecting. Nature 416 (2002) 15
49. Rosskopf F., Kraus J., and Franz G. Immunological and antitumor effects of coumarin and some derivatives. Pharmazie 47 (1992) 139-142
50. Roussi S., Winter A., Gosse F., Werner D., Zhang X., Marchioni E., Geoffroy P., Miesch M., and Raul F. Different apoptotic mechanisms are involved in the antiproliferative effects of 7beta-hydroxysitosterol and 7beta-hydroxycholesterol in human colon cancer cells. Cell Death Differ. 12 (2005) 128-135
51. Rubinstein L.V., Shoemaker R.H., Paull K.D., Simon R.M., Tosini S., Skehan P., Scudiero D.A., and Boyd M.R. Comparison of in vitro anticancer-drug-screening data generated with a tretrazolium assay versus a protein assay against a diverse panel of human tumour cell lines. J. Natl. Cancer Inst. 82 (1990) 1113-1118
52. Saleem A., Husheem M., Harkonen P., and Pihlaja K. Inhibition of cancer cell growth by crude extract and the phenolics of Terminalia chebula retz. Fruit. J. Ethnopharmacol. 81 (2002) 327-336
53. Schiff P.B., Fant J., and Horwitz S.B. Promotion of microtubule assembly in vitro by taxol. Nature 277 (1979) 665-667
54. Singleton V.L., and Rossi J.A. Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents. Am. J. Enol. Vitic. 16 (1965) 144-158
55. Soejarto D.D., Gyllenhaal C., Fong H.H., Xuan L.T., Hiep N.T., Hung N.V., Bich T.Q., Southavong B., Sydara K., and Pezzuto J.M. The UIC ICBG (University of Illinois at Chicago International Cooperative Biodiversity Group) Memorandum of Agreement: a model of benefit-sharing arrangement in natural products drug discovery and development. J. Nat. Prod. 67 (2004) 294-299
56. Triantaphyllou K., Blekas G., and Boskou D. Antioxidative properties of water extracts obtained from herbs of the species Lamiaceae. Int. J. Food Sci. Nutr. 52 (2001) 313-317
57. Tutin, T.G., Burges, N.A., Chater, A.O., Edmondson, J.R., Heywood, V.H., Moore, D.M., Valentine, D.H., Walters, S.M., Webb, D.A. (Eds.), 1993. Flora Europaea, vol. 1. Cambridge University Press, Cambridge.
58. van Der Heijden R., Jacobs D.I., Snoeijer W., Hallard D., and Verpoorte R. The Catharanthus alkaloids: pharmacognosy and biotechnology. Curr. Med. Chem. 11 (2004) 607-628
59. Wall M.E., and Wani M.C. Camptothecin and taxol: from discovery to clinic. J. Ethnopharmacol. 51 (1996) 239-253
60. Yáñez J., Vicente V., Alcaraz M., Castillo J., Benavente-García O., Canteras M., and Teruel J.A. Cytotoxicity and antiproliferative activities of several phenolic compounds against three melanocytes cell lines: relationship between structure and activity. Nutr. Cancer 49 (2004) 191-199
61. Yasukawa K., Akihisa T., Oinuma H., Kaminaga T., Kanno H., Kasahara Y., Tamura T., Kumaki K., Yamanouchi S., and Takido M. Inhibitory effect of taraxastane-type triterpenes on tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin. Oncology 53 (1996) 341-344
62. Zhang Y., Vareed S.K., and Nair M.G. Human tumor cell growth inhibition by non-toxic anthocyanidins, the pigments in fruits and vegetables. Life Sci. 76 (2005) 1465-1472
63. Zhao Y.H., Ji G.D., Cronin M.T.D., and Dearden J.C. QSAR study of the toxicity of benzoic acids to Vibrio fischeri, Daphnia magna and carp. Sci. Total Environ. 216 (1998) 205-215
64. Zurita J.L., Jos A., del Peso A., Salguero M., Lopez-Artìguez M., and Repetto G. Ecotoxicological assessment of bromobenzene using a test battery with five model systems. Food Chem. Toxicol. 45 (2007) 575-584