Phosphatidylinositol 4,5-bisphosphate hydrolysis mediates histamine-induced KCNQ/M current inhibition

American Journal of Physiology - Cell Physiology

Volumn 295, Issue 1, 2008, Pages

  Liu, Boyi ^a   Liang, Huiling ^a   Liu, Li ^a   Zhang, Hailin ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

Calcium ion; Phosphatidylinositol 4,5 bisphosphate; Superior cervical ganglion

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; CIMETIDINE; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; HISTAMINE; HISTAMINE H1 RECEPTOR; MEPYRAMINE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOLIPASE C; POTASSIUM CHANNEL KCNQ; POTASSIUM CHANNEL KCNQ3; 1 (6 ((3 METHOXYESTRA 1,3,5(10) TRIEN 17 YL)AMINO)HEXYL) 1H PYRROLE 2,5 DIONE; 1-(6-((3-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL)AMINO)HEXYL)-1H-PYRROLE-2,5-DIONE; 2 PYRROLIDONE DERIVATIVE; CALCIUM; ESTRANE DERIVATIVE; KCNQ2 PROTEIN, RAT; KCNQ3 PROTEIN, HUMAN; POTASSIUM CHANNEL KCNQ2;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM CELL LEVEL; CELL STRAIN HEK293; CERVICAL GANGLION; CONTROLLED STUDY; CYTOSOL; EMBRYO; FLUORESCENCE; HUMAN; HUMAN CELL; HYDROLYSIS; NERVE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; ANIMAL; CELL LINE; CELL MEMBRANE; CHANNEL GATING; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; PHYSIOLOGY;

RATTUS;

ANIMALS; CALCIUM; CELL LINE; CELL MEMBRANE; ESTRENES; HISTAMINE; HUMANS; HYDROLYSIS; ION CHANNEL GATING; KCNQ2 POTASSIUM CHANNEL; KCNQ3 POTASSIUM CHANNEL; NEURONS; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PYRILAMINE; PYRROLIDINONES; RATS; RECEPTORS, HISTAMINE H1; TYPE C PHOSPHOLIPASES;

EID: 52749092134     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00028.2008     Document Type: Article

References (46)

1. 2+ current and M current in rat sympathetic neurons. Proc Natl Acad Sci USA 88: 652-656, 1991.
2. Brown BS, Yu SP. Modulation and genetic identification of the M channel. Prog Biophys Mol Biol 73: 135-166, 2000.
3. 2 hydrolysis: significance for receptor-mediated inhibition. J Physiol 582: 917-925, 2007.
4. Brown RE, Stevens DR, Haas HL. The physiology of brain histamine. Prog Neurobiol 63: 637-672, 2001.
5. Christian EP, Undem BJ, Weinreich D. Endogenous histamine excites neurones in the guinea-pig superior cervical ganglion in vitro. J Physiol 409: 297-312, 1989.
6. 3 receptors modulate sympathetic ganglionic synaptic transmission in the guinea-pig. J Physiol 457: 407-430, 1992.
7. 2+ stores in rat sympathetic neurons. Proc Natl Acad Sci USA 95: 7151-7156, 1998.
8. Dalby-Brown W, Hansen HH, Korsgaard MP, Mirza N, Olesen SP. K(v)7 channels: function, pharmacology and channel modulators. Curr Top Med Chem 6: 999-1023, 2006.
9. Delmas P, Brown DA. Pathways modulating neural KCNQ/M (Kv7) potassium channels. Nat Rev Neurosci 6: 850-862, 2005.
10. Delmas P, Crest M, Brown DA. Functional organization of PLC signaling microdomains in neurons. Trends Neurosci 27: 41-47, 2004.
11. 3 pathways in neurons. Neuron 34: 209-220, 2002.
12. 4 receptor to neuronal ion channels. Br J Pharmacol 138: 400-406, 2003.
13. Ford CP, Stemkowski PL, Smith PA. Possible role of phosphatidylinositol 4, 5 bisphosphate in luteinizing hormone releasing hormone-mediated M-current inhibition in bullfrog sympathetic neurons. Eur J Neurosci 20: 2990-2998, 2004.
14. 2+/calmodulin. Mol Biol Cell 16: 3538-3551, 2005.
15. 2+ channels. J Neurosci 24: 10980-10992, 2004.
16. + channels. J Gen Physiol 122: 17-31, 2003.
17. Gamper N, Shapiro MS. Regulation of ion transport proteins by membrane phosphoinositides. Nat Rev Neurosci 8: 921-934, 2007.
18. 2 signaling: how might it work? J Physiol 582: 967-975, 2007.
19. + channels as a mechanism of cytoprotective neuronal silencing. EMBO J 25: 4996-5004, 2006.
20. Guo J, Schofield GG. Activation of a PTX-insensitive G protein is involved in histamine-induced recombinant M-channel modulation. J Physiol 545: 767-781, 2002.
21. Guo J, Schofield GG. Histamine inhibits KCNQ2/KCNQ3 channel current via recombinant histamine H1 receptors. Neurosci Lett 328: 285-288, 2002.
22. Hernandez CC, Zaika O, Tolstykh GP, Shapiro MS. Regulation of neural KCNQ channels: signalling pathways, structural motifs and functional implications. J Physiol 586: 1811-1821, 2008.
23. 2+ requirement, and regulation of M current. J Gen Physiol 126: 243-262, 2005.
24. Hoshi N, Zhang JS, Omaki M, Takeuchi T, Yokoyama S, Wanaverbecq N, Langeberg LK, Yoneda Y, Scott JD, Brown DA, Higashida H. AKAP150 signaling complex promotes suppression of the M-current by muscarinic agonists. Nat Neurosci 6: 564-571, 2003.
25. Jia Q, Jia Z, Zhao Z, Liu B, Liang H, Zhang H. Activation of epidermal growth factor receptor inhibits KCNQ2/3 current through two distinct pathways: membrane PtdIns(4,5)P2 hydrolysis and channel phosphorylation. J Neurosci 27: 2503-2512, 2007.
26. 2 receptors and G alpha q/11. Neuron 14: 399-405, 1995.
27. + leakage conductance. Neuroscience 70: 145-158, 1996.
28. 2) on ganglionic transmission and on accumulation of cyclic nucleotides (cAMP and cGMP) in rat superior cervical ganglion in vitro. Neuropharmacology 22: 203-211, 1983.
29. Liu B, Zhang X, Wang C, Zhang G, Zhang H. Antihistamine mepyramine directly inhibits KCNQ/M channel and depolarizes rat superior cervical ganglion neurons. Neuropharmacology 54: 629-639, 2008.
30. Ma C, Greenquist KW, Lamotte RH. Inflammatory mediators enhance the excitability of chronically compressed dorsal root ganglion neurons. J Neurophysiol 95: 2098-2107, 2006.
31. Machova J, Kristofova A. The actions of histamine in cat and rabbit superior cervical ganglia. Agents Actions 23: 260-262, 1988.
32. Selyanko AA, Brown DA. Regulation of M-type potassium channels in mammalian sympathetic neurons: action of intracellular calcium on single channel currents. Neuropharmacology 35: 933-947, 1996.
33. + channels that underlie the neuronal M current. J Neurosci 20: 1710-1721, 2000.
34. Shapiro MS, Wollmuth LP, Hille B. Angiotensin II inhibits calcium and M current channels in rat sympathetic neurons via G proteins. Neuron 12: 1319-1329, 1994.
35. 2+ channel activity by phenylarsine oxide. Br J Pharmacol 142: 797-807, 2004.
36. Snow RW, Weinreich D. Presynaptic and postsynaptic effects of histamine and histamine agonists in the superior cervical ganglion of the rat. Neuropharmacology 26: 743-752, 1987.
37. Stauffer TP, Ahn S, Meyer T. Receptor-induced transient reduction in plasma membrane PtdIns(4,5)P2 concentration monitored in living cells. Curr Biol 8: 343-346, 1998.
38. Suh BC, Hille B. Recovery from muscarinic modulation of M current channels requires phosphatidylinositol 4, 5-bisphosphate synthesis. Neuron 35: 507-520, 2002.
39. Suh BC, Hille B. Regulation of ion channels by phosphatidylinositol 4, 5-bisphosphate. Curr Opin Neurobiol 15: 370-378, 2005.
40. Wallace DJ, Chen C, Marley PD. Histamine promotes excitability in bovine adrenal chromaffin cells by inhibiting an M-current. J Physiol 540: 921-939, 2002.
41. Whyment AD, Blanks AM, Lee K, Renaud LP, Spanswick D. Histamine excites neonatal rat sympathetic preganglionic neurons in vitro via activation of H1 receptors. J Neurophysiol 95: 2492-2500, 2006.
42. Xu C, Watras J, Loew LM. Kinetic analysis of receptor-activated phosphoinositide turnover. J Cell Biol 161: 779-791, 2003.
43. + channels. J Physiol 575: 49-67, 2006.
44. 2Y receptor regulation of neuronal ion channels. J Neurosci 27: 8914-8926, 2007.
45. 2 activates KCNQ channels, and its hydrolysis underlies receptor-mediated inhibition of M currents. Neuron 37: 963-975, 2003.
46. Zhou J, Lee AW, Devidze N, Zhang Q, Kow LM, Pfaff DW. Histamine-induced excitatory responses in mouse ventromedial hypothalamic neurons: ionic mechanisms and estrogenic regulation. J Neurophysiol 98: 3143-3152, 2007.