The aldose reductase inhibitory capacity of Sorbus domestica fruit extracts depends on their phenolic content and may be useful for the control of diabetic complications

Pharmazie

Volumn 63, Issue 9, 2008, Pages 693-696

  Termentzi, A ^a   Alexiou, P ^a   Demopoulos, V J ^a   Kokkalou, Eugene ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID ETHYL ESTER; ALDEHYDE REDUCTASE; ESTER DERIVATIVE; ETHER; FLAVONOID; PHENOL; PLANT EXTRACT; SORBUS DOMESTICA EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE CONTROL; ELECTROSPRAY MASS SPECTROMETRY; ENZYME INHIBITION; FRUIT; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; NONHUMAN; RAT; SORBUS; SORBUS DOMESTICA;

ALDEHYDE REDUCTASE; ANIMALS; DIABETES COMPLICATIONS; ENZYME INHIBITORS; FEMALE; FRUIT; INDICATORS AND REAGENTS; LENS, CRYSTALLINE; MALE; PHENOLS; PLANT EXTRACTS; RATS; RATS, INBRED F344; SOLVENTS; SORBUS;

EID: 52649156576     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: 10.1691/ph.2008.8567     Document Type: Article

References (22)

1. Constantino L, Rastelli G, Vianello P, Cignarella G, Barlocco D (1999a) Diabetes complication and their potential prevention: Aldose reductase inhibition and other aproaches. Med Res Rev 19: 3-23.
2. Constantino L, Rastelli G, Gamberini MC, Vinson JA, Bose P, Iannone A, Staffieri M, Antolini L, Del Corso A, Mura U, Albasini A (1999b) 1-Benzopyran-4-one antioxidants as aldose reductase inhibitors. J Med Chem 42: 1881-1893.
3. Demopoulos VJ, Nicolaou I, Alexiou P, Zika C, Sturm S, Kristl A (2007) Brilliant Light in Life and Material Sciences. In: Tsakanov V, Wiedemann H (eds.) Novel chemotypes in pharmacochemical approaches: Focus on aldose reductase enzyme inhibitors, The Netherlands: Springer, p. 241.
4. Du G-H, Qiu Y, Tian Y-E, Zhang J-T (1995) Prevention of galactose-induced cataractogenesis in rats by salvianolic acid A. Acta Pharm Sín 30: 561-566.
5. Kasimu R, Tanaka K, Tezuka Y, Gong Z-N, Li J-X, Basnet P, Namba T, Kadota S (1998) Comparative study of seventeen Salvia plants: aldose reductase inhibitory activity of water and MeOH extracts and LC-MS analysis of water extracts. Chem Pharm Bull 46: 500-504.
6. Koukoulitsa C, Zika C, Geromichalos GD, Demopoulos V, Skaltsa H (2006) Evaluation of aldose reductase inhibition and docking studies of some secondary metabolites, isolated from Origanum vulgare L. ssp. hirtum. Bioorg & Med Chem 14: 1653-1659.
7. Logendra S, Ribnicky D, Yang H, Poulev A, Ma J, Kennelly E, Raskin I (2006) Bioassay- guided isolation of aldose reductase inhibitors from Artemisia dracunculus. Phytochem 67: 1539-1546.
8. Matthew J, Sheetz MD, King GL (2002) Molecular understanding of hyperglycemia's adverse effects for diabetic complications. J Amer Med Assoc 288: 2579-2588.
9. Mellidis AS, Papageorgiou VP, Kokkalou E (1993) Phenolic constituents from Onosma heterophylla. J Nat Prod 56: 949-952.
10. Miyamoto S (2002) Molecular modelling and structure-based drag discovery studies of aldose reductase inhibitors. Chem-Bio Inform J 2: 74-85.
11. Nicolaou I, Zika C, Demopoulos VJ (2004) [1-(3,5-difluoro-4- hydroxyphenyl)-1H-pyrrol-3-yl] phenylmethanone as a bioisostere of a carboxylic acid aldose reductase inhibitor. J Med Chem 47: 2706-2709.
12. Olschlager C, Milde J, Schempp H, Treutter D (2004) Polyphenols and antioxidant capacity of Sorbus domestica L. fruits. Angewandte Botanik 78: 112-116.
13. Rastelli G, Antolini L, Benvenuti S, Constantino L (2000) Structural bases for the inhibition of aldose reductase by phenolic compounds. Bioorg & Medic Chem 8: 1151-1158.
14. Ravn H, Nishibe S, Sasahara M, Xuebo L (1990) Phenolic compounds from Plantago asiatica. Phytochem 29: 3627-3631.
15. Terashima S, Shimizu M, Nakayama H, Ishikura M, Ueda Y, Imai K, Suzui A, Morita N (1990) Studies on aldose reductase inhibitors from medicinal plant of "Sinfito", Potentilla candicans, and further synthesis of their related compounds. Chem Pharm Bull 38: 2733-2736.
16. Termentzi A, Kefalas P, Kokkalou E (2006) Antioxidant activities of various extracts and fractions of Sorbus domestica fruit at different maturity stages. Food Chem 98: 599-608.
17. Termentzi A, Kefalas P, Kokkalou E (2006) LC-DAD-MS (ESI+) analysis of the phenolic content of Sorbus domestica fruits in relation to their maturity stage. Food Chem 106: 1234-1245.
18. Urzumtzev A, Tete-Favier F, Mitscier A, Barbanton J, Barth P, Urzhumgtseva L, Biellmann JF, Podjarny AD, Moras D (1997) A 'specificity' pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil. Structure 5: 601-612.
19. Varma SD, Kinoshita JH (1976) Inhibition of lens aldose reductase by flavonoids - Their possible role in the prevention of diabetic cataracts. Biochem Pharmacol 25: 2505-2513.
20. Yawadio R, Tanimori S, Morita N (2006) Identification of phenolic compounds isolated from pigmented rices and their aldose reductase inhibitory activities. Food Chem 101: 1616-1625.
21. Zaher N, Nicolaou I, Demopoulos VJ (2002) Pyrrolylbenzothiazole derivatives as aldose reductase inhibitors. J Enzym Inhib Med Chem 17: 131-135.
22. Ziegler D (2004) Polyneuropathy in the diabetic patients-update on pathogenesis and management. Nephrol Dial Transplant 19: 2170-2175.