P311 functions in an alternative pathway of lipid accumulation that is induced by retinoic acid

Journal of Cell Science

Volumn 121, Issue 16, 2008, Pages 2751-2758

  Leung, James K ^a   Cases, Sylvaine ^b   Vu, Thiennu H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

Author keywords

Lipid droplet Accumulation; P311 (DOH4S114, C5orf13); Retinoic acid

Indexed keywords

CHOLESTEROL; CHROMOSOME 5 OPEN READING FRAME 13; FAT DROPLET; GENE PRODUCT; RETINOIC ACID; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL REGENERATION; CELL STRAIN 3T3; CONTROLLED STUDY; EMBRYO; GENE CONTROL; GENE EXPRESSION REGULATION; LIPID STORAGE; LIPOGENESIS; LUNG DEVELOPMENT; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FUNCTION; UPREGULATION;

3T3-L1 CELLS; ANIMALS; CELLS, CULTURED; FIBROBLASTS; GENE SILENCING; LIPID METABOLISM; LUNG; MICE; MICE, INBRED C57BL; NERVE TISSUE PROTEINS; NIH 3T3 CELLS; REGENERATION; SIGNAL TRANSDUCTION; TRETINOIN; UP-REGULATION;

EID: 52649084330     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.027151     Document Type: Article

References (45)

1. Abumrad, N. A., Perkins, R. C., Park, J. H. and Park, C. R. (1981). Mechanism of long chain fatty acid permeation in the isolated adipocyte. J. Biol. Chem. 256, 9183-9191.
2. Abumrad, N. A., Park, J. H. and Park, C. R. (1984). Permeation of long-chain fatty acid into adipocytes. Kinetics, specificity, and evidence for involvement of a membrane protein. J. Biol. Chem. 259, 8945-8953.
3. Badman, M. K. and Flier, J. S. (2007). The adipocyte as an active participant in energy balance and metabolism. Gastroenterology 132, 2103-2115.
4. Bruce, M. C. and Honaker, C. E. (1998). Transcriptional regulation of tropoelastin expression in rat lung fibroblasts: changes with age and hyperoxia. Am. J. Physiol. 274, L940-L950.
5. Cermelli, S., Guo, Y., Gross, S. P. and Welte, M. A. (2006). The lipid-droplet proteome reveals that droplets are a protein-storage depot. Curr. Biol. 16, 1783-1795.
6. Chen, H., Jackson, S., Doro, M. and McGowan, S. (1998). Perinatal expression of genes that may participate in lipid metabolism by lipid-laden lung fibroblasts. J. Lipid Res. 39, 2483-2492.
7. Chytil, F. (1996). Retinoids in lung development. FASEB J. 10, 986-992.
8. Dani, C., Smith, A. G., Dessolin, S., Leroy, P., Staccini, L., Villageois, P., Darimont, C. and Ailhaud, G. (1997). Differentiation of embryonic stem cells into adipocytes in vitro. J. Cell Sci. 110, 1279-1285.
9. Dutta-Roy, A. K. (2000). Cellular uptake of long-chain fatty acids: role of membrane-associated fatty-acid-binding/transport proteins. Cell. Mol. Life Sci. 57, 1360-1372.
10. Dvorak, A. M., Dvorak, H. F., Peters, S. P., Shulman, E. S., MacGlashan, D. W., Jr, Pyne, K., Harvey, V. S., Galli, S. J. and Lichtenstein, L. M. (1983). Lipid bodies: cytoplasmic organelles important to arachidonate metabolism in macrophages and mast cells. J. Immunol. 131, 2965-2976.
11. Fujitani, M., Yamagishi, S., Che, Y. H., Hata, K., Kubo, T., Ino, H., Tohyama, M. and Yamashita, T. (2004). P311 accelerates nerve regeneration of the axotomized facial nerve. J. Neurochem. 91, 737-744.
12. Green, H. and Meuth, M. (1974). An established pre-adipose cell line and its differentiation in culture. Cell 3, 127-133.
13. Green, S. (1995). PPAR: a mediator of peroxisome proliferator action. Mutat. Res. 333, 101-109.
14. Hettinger, A. M., Allen, M. R., Zhang, B. R., Goad, D. W., Malayer, J. R. and Geisert, R. D. (2001). Presence of the acute phase protein, bikunin, in the endometrium of gilts during estrous cycle and early pregnancy. Biol. Reprod. 65, 507-513.
15. Hind, M. and Maden, M. (2004). Retinoic, acid induces alveolar regeneration in the adult mouse lung. Eur. Respir. J. 23, 20-27.
16. Inazawa, Y., Nakatsu, M., Yasugi E., Saeki, K. and You, A. (2003). Lipid droplet formation in human myeloid NB4 cells stimulated by all trans refinoic acid and granulocyte colony-stimulating factor: possible involvement of peroxisome proliferator-activated receptor gamma. Cell. Struct. Funct. 28, 487-493.
17. Kaplan, N. B., Grant, M. M. and Brody, J. S. (1985). The lipid interstitial cell of the pulmonary alveolus. Age and species differences. Am. Rev. Respir. Dis. 132, 1307-1312.
18. Liu, B., Harvey, C. S. and McGowan, S. E. (1993). Retinoic acid increases elastin in neonatal rat lung fibroblast cultures. Am. J. Physiol. 265, L430-L437.
19. Maden, M. and Hind, M. (2003). Retinoic acid, a regeneration-inducing molecule. Dev. Dyn. 226, 237-244.
20. Maden, M. and Hind, M. (2004). Retinoic acid in alveolar development, maintenance and regeneration. Philos. Trans. R. Soc. Lond, B, Biol. Sci. 359, 799-808.
21. Mariani, L., McDonough, W. S., Hoelzinger, D. B., Beaudry, C., Kaczmarek, E., Coons, S. W., Giese, A., Moghaddam, M., Seiler, R. W. and Berens, M. E. (2001). Identification and validation of bP311 as a glioblastoma invasion gene using laser capture microdissection. Cancer Res. 61, 4190-4196.
22. Martin, S. and Parton, R. G. (2005). Caveolin, cholesterol, and lipid bodies. Semin. Cell Dev. Biol. 16, 163-174.
23. Martin, S. and Parton, R. G. (2006). Lipid droplets: a unified view of a dynamic organelle. Nat. Rev. Mol. Cell. Biol. 7, 373-378.
24. Massaro, G. D. and Massaro, D. (1997). Retinoic acid treatment abrogates elastase-induced pulmonary emphysema in rats. Nat. Med. 3, 675-677.
25. McGowan, S. E. (2002). Contributions of retinoids to the generation and repair of the pulmonary alveolus. Chest 121, 206S-208S.
26. McGowan, S. E. and Torday, J. S. (1997). The pulmonary lipofibroblast (lipid interstitial cell) and its contributions to alveolar development. Annu. Rev. Physiol. 59, 43-62.
27. McGowan, S., Jackson, S. K., Jenkins-Moore, M., Dai, H. H., Chambon, P. and Snyder, J. M. (2000). Mice bearing deletions of retinoic acid receptors demonstrate reduced lung elastin and alveolar numbers. Am. J. Respir. Cell Mol. Biol. 23, 162-167.
28. Murphy, D. J. (2001). The biogenesis and functions of lipid bodies in animals, plants and microorganisms. Prog. Lipid Res. 40, 325-438.
29. Pan, D., Zhe, X., Jakkaraju, S., Taylor, G. A. and Schuger, L. (2002). P311 induces a TGF-beta1-independent, nonfibrogenic myofibroblast phenotype. J. Clin. Invest. 110, 1349-1358.
30. Pol, A., Martin, S., Fernandez, M. A., Ferguson, C, Carozzi A., Luetterforst, R., Enrich, C. and Parton, R. G. (2004). Dynamic and regulated association of caveolin with lipid bodies: modulation of lipid body motility and function by a dominant negative mutant. Mol. Biol. Cell 15, 99-110.
31. Safonova, L, Reichert, U., Shroot, B., Ailhaud, G. and Grimaldi, P. (1994). Fatty acids and retinoids act synergistically on adipose cell differentiation. Biochem. Biophys. Res. Commun. 204, 498-504.
32. Sato, M., Suzuki, S. and Senoo, H. (2003). Hepatic stellate cells: unique characteristics in cell biology and phenotype. Cell Struct. Funct. 28, 105-112.
33. Schwarz, E. J., Reginato, M. J., Shao, D., Krakow, S. L. and Lazar, M. A. (1997). Retinoic acid blocks adipogenesis by inhibiting C/ EBPbeta-mediated transcription. Mol. Cell. Biol. 17, 1552-1561.
34. Semeiks, J. R., Rizki, A., Bissell, M. J. and Mian, I. S. (2006). Ensemble attribute profile clustering: discovering and characterizing groups of genes with similar patterns of biological features. BMC Bioinformatics 7, 147.
35. Sironen, R., Elo, M., Kaarniranta, K., Helminen, H. J. and Lammi, M. J. (2000). Transcriptional activation in chondrocytes submitted to hydrostatic pressure. Biorheology 37, 85-93.
36. Snyder, J. M., Jenkins-Moore, M., Jackson, S. K., Goss, K. L., Dai, H. H., Bangsund, P. J., Giguere, V. and McGowan, S. E. (2005). Alveolarization in retinoic acid receptor-beta-deficient mice. Pediatr. Res. 57, 384-391.
37. Studler, J. M., Glowinski, J. and Levi-Strauss, M. (1993). An abundant mRNA of the embryonic brain persists at a high level in cerebellum, hippocampus and olfactory bulb during adulthood. Eur. J. Neurosci. 5, 614-623.
38. Toth, I. E., Szabo, D. and Bruckner, G. G. (1997). Lipoproteins, lipid droplets, lysosomes, and adrenocortical steroid hormone synthesis: morphological studies. Microsc. Res. Tech. 36, 480-492.
39. Vaccaro, C. and Brody, J. S. (1978). Ultrastructure of developing alveoli. I. The role of the interstitial fibroblast. Anat. Rec. 192, 467-479.
40. Ventura, A., Meissner, A., Dillon, C. P., McManus, M., Sharp, P. A., Van Parijs, L., Jaenisch, R. and Jacks, T. (2004). Cre-lox-regulated conditional RNA interference from transgenes. Proc. Natl. Acad. Sci. USA 101, 10380-10385.
41. Wake, K. and Sato, T. (1993). Intralobular heterogeneity of perisinusoidal stellate cells in porcine liver. Cell Tissue Res. 273, 227-237.
42. Wan, H. C., Melo, R. C., Jin, Z., Dvorak, A. M. and Weiler, P. F. (2007). Roles and origins of leukocyte lipid bodies: proteomic and ultrastructural studies. FASEB J. 21, 167-178.
43. Yan, D., Lehto, M., Rasilainen, L., Metso, J., Ehnholm, C., Yla-Herttuala, S., Jauhiainen, M. and Olkkonen, V. M. (2007). Oxysterol binding protein induces upregulation of SREBP-1c and enhances hepatic lipogenesis. Arterioscler. Thromb. Vasc. Biol. 27, 1108-1114.
44. Yang, L., Naltner, A. and Yan, C. (2003). Overexpression of dominant negative retinoic acid receptor alpha causes alveolar abnormality in transgenic neonatal lungs. Endocrinology 144, 3004-3011.
45. Zhao, L., Leung, J. K., Yamamoto, H., Goswami, S., Kheradmand, F. and Vu, T. H. (2006). Identification of P311 as a potential gene regulating alveolar generation. Am. J. Respir. Cell Mol. Biol. 35, 48-54.