Alveolarization in retinoic acid receptor-β-deficient mice

Pediatric Research

Volumn 57, Issue 3, 2005, Pages 384-391

  Snyder, Jeanne M ^a,d   Jenkins Moore, Melinda ^a   Jackson, Sheila K ^a,b   Goss, Kelli L ^a   Dai, Hui Hui ^a,b   Bangsund, Peter J ^a   Giguere, Vincent ^c   Mcgowan, Stephen E ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b Medical Center   (United States)

^c MCGILL UNIVERSITY   (Canada)

^d 1 550 Bowen Science Building ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BROXURIDINE; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR; RETINOIC ACID; RETINOIC ACID RECEPTOR; RETINOID X RECEPTOR;

ANIMAL MODEL; ARTICLE; BREATHING RATE; FETUS LUNG MATURATION; GENE DELETION; LUNG ALVEOLUS; LUNG GAS EXCHANGE; LUNG PARENCHYMA; LUNG VOLUME; MORPHOMETRICS; MOUSE; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; RESPIRATORY FAILURE; TIDAL VOLUME; WILD TYPE;

ANIMALS; FEMALE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PLATELET-DERIVED GROWTH FACTOR; PROTEIN ISOFORMS; PULMONARY ALVEOLI; RANDOM ALLOCATION; RECEPTORS, RETINOIC ACID; RETINOIDS;

EID: 14344252095     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/01.PDR.0000151315.81106.D3     Document Type: Article

References (43)

1. Chytil F 1996 Retinoids in lung development. FASEB J 10:986-992
2. Frickel J 1984 Chemistry and physical properties of retinoids. In: Roberts AB, Goodman DS (eds) The Retinoids. Academic Press, Orlando, pp 80-145
3. Chambon P 1996 A decade of molecular biology of retinoic acid receptors. FASEB J 10:940-954
4. Massaro GD, Massaro D 1996 Postnatal treatment with retinoic acid increases the number of pulmonary alveoli in rats. Am J Physiol 270:L305-L310
5. Massaro GD, Massaro D 1997 Retinoic acid treatment abrogates elastase-induced pulmonary emphysema in rats. Nat Med 3:675-677
6. Lucey EC, Goldstein RH, Breuer R, Rexer BN, Ong DE, Snider GL 2003 Retinoic acid does not affect alveolar septation in adult FVB mice with elastase-induced emphysema. Respiration 70:200-205
7. Fujita M, Ye Q, Ouchi H, Nakashima N, Hamada N, Hagimoto N, Kuwano K, Mason RJ, Nakanishi Y 2004 Retinoic acid fails to reverse emphysema in adult mouse models. Thorax 59:224-230
8. McGowan S, Jackson SK, Jenkins-Moore M, Dai HH, Chambon P, Snyder JM 2000 Mice bearing deletions of retinoic acid receptors demonstrate reduced lung elastin and alveolar numbers. Am J Respir Cell Mol Biol 23:162-167
9. Massaro GD, Massaro D, Chambon P 2003 Retinoic acid receptor-alpha regulates pulmonary alveolus formation in mice after, but not during, perinatal period. Am J Physiol 284:L431-L433
10. Massaro GD, Massaro D, Chan WY, Clerch LB, Ghyselinck N, Chambon P, Chandraratna RA 2000 Retinoic acid receptor-beta: an endogenous inhibitor of the perinatal formation of pulmonary alveoli. Physiol Genomics 4:51-57
11. Luo J, Pasceri P, Conlon RA, Rossant J, Giguere V 1995 Mice lacking all isoforms of retinoic acid receptor beta develop normally and are susceptible to the teratogenic effects of retinoic acid. Mech Dev 53:61-71
12. Weibel E 1979 Stereological Methods. Vol 1, Practical Methods for Biological Morphometry. Academic Press, New York
13. Kawakami M, Paul JL, Thurlbeck WM 1984 The effect of age on lung structure in male BALB/cNNia inbred mice. Am J Anat 170:1-21
14. Gundersen HJ, Jensen EB 1987 The efficiency of systematic sampling in stereology and its prediction. J Microsc 147(suppl):229-263
15. Gundersen HJ, Bendtsen TF, Korbo L, Marcussen N, Moller A, Nielsen K, Nyengaard JR, Pakkenberg B, Sorensen FB, Vesterby A, et al. 1988 Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. APMIS 96:379-394
16. Zar JH 1984 Biostatistical Analysis. Prentice-Hall, Englewood Cliffs, NJ
17. Schroter RC 1980 Quantitative comparisons of mammalian lung pressure volume curves. Respir Physiol 42:101-107
18. Dekowski SA, Snyder JM 1992 Insulin regulation of messenger ribonucleic acid for the surfactant-associated proteins in human fetal lung in vitro. Endocrinology 131:669-676
19. Chen H, Jackson S, Doro M, McGowan S 1998 Perinatal expression of genes that may participate in lipid metabolism by lipid-laden lung fibroblasts. J Lipid Res 39:2483-2492
20. McGowan SE, Harvey CS, Jackson SK 1995 Retinoids, retinoic acid receptors, and cytoplasmic retinoid binding proteins in perinatal rat lung fibroblasts. Am J Physiol 269:L463-L472
21. Bradford MM 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
22. George TN, Snyder JM 1997 Regulation of surfactant protein gene expression by retinoic acid metabolites. Pediatr Res 41:692-701
23. Amy RW, Bowes D, Burri PH, Haines J, Thurlbeck WM 1977 Postnatal growth of the mouse lung. J Anat 124:131-151
24. Bostrom H, Willetts K, Pekny M, Leveen P, Lindahl P, Hedstrand H, Pekna M, Hellstrom M, Gebre-Medhin S, Schalling M, Nilsson M, Kurland S, Tornell J, Heath JK, Betsholtz C 1996 PDGF-A signaling is a critical event in lung alveolar myofibroblast development and alveogenesis. Cell 85:863-873
25. Lindahl P, Karlsson L, Hellstrom M, Gebre-Medhin S, Willetts K, Heath JK, Betsholtz C 1997 Alveogenesis failure in PDGF-A-deficient mice is coupled to lack of distal spreading of alveolar smooth muscle cell progenitors during lung development. Development 124:3943-3953
26. Chambon P 1995 The molecular and genetic dissection of the retinoid signaling pathway. Recent Prog Horm Res 50:317-332
27. Ghyselinck NB, Dupe V, Dierich A, Messaddeq N, Garnier JM, Rochette-Egly C, Chambon P, Mark M 1997 Role of the retinoic acid receptor β (RARβ) during mouse development. Int J Dev Biol 41:425-447
28. Mendelsohn C, Lohnes D, Decimo D, Lufkin T, LeMeur M, Chambon P, Mark M 1994 Function of the retinoic acid receptors (RARs) during development (II). Multiple abnormalities at various stages of organogenesis in RAR double mutants. Development 120:2749-2771
29. Underhill TM, Kotch LE, Linney E 1995 Retinoids and mouse embryonic development. Vitam Horm 51:403-457
30. Mollard R, Ghyselinck NB, Wendling O, Chambon P, Mark M 2000 Stage-dependent responses of the developing lung to retinoic acid signaling. Int J Dev Biol 44:457-462
31. Hind M, Corcoran J, Maden M 2002 Temporal/spatial expression of retinoid binding proteins and RAR isoforms in the postnatal lung. Am J Physiol 282:L468-L476
32. Yang L, Naltner A, Yan C 2003 Overexpression of dominant negative retinoic acid receptor alpha causes alveolar abnormality in transgenic neonatal lungs. Endocrinology 144:3004-3011
33. Jakkula M, Le Cras TD, Gebb S, Hirth KP, Tuder RM, Voelkel NF, Abman SH 2000 Inhibition of angiogenesis decreases alveolarization in the developing rat lung. Am J Physiol 279:L600-L607
34. Le Cras TD, Markham NE, Tuder RM, Voelkel NF, Abman SH 2002 Treatment of newborn rats with a VEGF receptor inhibitor causes pulmonary hypertension and abnormal lung structure. Am J Physiol 283:L555-L562
35. Afink GB, Nister M, Stassen BH, Joosten PH, Rademakers PJ, Bongcam-Rudloff E, Van Zoelen EJ, Mosselman S 1995 Molecular cloning and functional characterization of the human platelet-derived growth factor alpha receptor gene promoter. Oncogene 10:1667-1672
36. Mummery CL, van den Eijnden-van Raaij AJ, Feijen A, Freund E, Hulskotte E, Schoorlemmer J, Kruijer W 1990 Expression of growth factors during the differentiation of embryonic stem cells in monolayer. Dev Biol 142:406-413
37. Wang C, Kelly J, Bowen-Pope DF, Stiles CD 1990 Retinoic acid promotes transcription of the platelet-derived growth factor alpha-receptor gene. Mol Cell Biol 10:6781-6784
38. Liebeskind A, Srinivasan S, Kaetzel D, Bruce M 2000 Retinoic acid stimulates immature lung fibroblast growth via a PDGF-mediated autocrine mechanism. Am J Physiol 279:L81-L90
39. Randell SH, Mercer RR, Young SL 1990 Neonatal hyperoxia alters the pulmonary alveolar and capillary structure of 40-day-old rats. Am J Pathol 136:1259-1266
40. Massaro D, Massaro GD 2002 Pre- and postnatal lung development, maturation, and plasticity invited review: pulmonary alveoli: formation, the "call for oxygen," and other regulators. Am J Physiol 282:L345-L358
41. Nagai A, Katayama M, Thurlbeck WM, Matsui R, Yasui S, Konno K 1995 Effect of indomethacin on lung development in postnatal rats: possible role of prostaglandin in alveolar formation. Am J Physiol 268:L56-L62
42. Kida K, Thurlbeck WM 1980 The effects of beta-aminopropionitrile on the growing rat lung. Am J Pathol 101:693-710
43. Snyder JM 2004 Regulation of alveolarization. In: Polin RA, Fox WW, Abman S (eds) Fetal and Neonatal Physiology. Saunders, Philadelphia, pp 794-801