Contributions of retinoids to the generation and repair of the pulmonary alveolus

Chest

Volumn 121, Issue 5 SUPPL., 2002, Pages 206S-208S

  McGowan, Stephen E ^a  

^a UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

Author keywords

Alveolar development; Branching; Emphysema; Fibroblast; Growth factors; Lung development; Retinoic acid

Indexed keywords

GROWTH FACTOR; RETINOIC ACID; RETINOID DERIVATIVE;

AIRFLOW; CELL DIFFERENTIATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONFERENCE PAPER; DESTRUCTION; DISEASE ASSOCIATION; DRUG EFFECT; EMPHYSEMA; EPITHELIUM CELL; GENE EXPRESSION; HUMAN; INFLAMMATION; LUNG ALVEOLUS; LUNG ALVEOLUS CELL; LUNG COMPLIANCE; LUNG DEVELOPMENT; LUNG FUNCTION; MAMMAL; MESENCHYME; NONHUMAN; PRIORITY JOURNAL; REDUCTION;

EID: 0036260908     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.121.5_suppl.206S     Document Type: Conference Paper

References (11)

1. Retinoic acid treatment abrogates elastase-induced pulmonary emphysema in rats
2. Commitment and differentiation of lung cell lineages
3. The pulmonary lipofibroblast (lipid interstitial cell) and its contributions to alveolar development
4. Vitamin A storage in lungs during perinatal development in the rat
5. Retinoids in lung development
6. Peroxisome proliferators alter lipid acquisition and elastin gene expression in neonatal rat lung fibroblasts
7. Retinoic acid increases elastin in neonatal rat lung fibroblast cultures
8. Endogenous retinoids increase perinatal elastin gene expression in rat lung fibroblasts and fetal explants
9. Retinoids, retinoic acid receptors, and cytoplasmic retinoid binding proteins in perinatal rat lung fibroblasts
10. Mice bearing deletions of retinoic acid receptors demonstrate reduced lung elastin and alveolar numbers
11. Retinoic acid treatment partially rescues failed septation in rats and in mice