Kinetics of anti-carcinoembryonic antigen antibody internalization: Effects of affinity, bivalency, and stability

Cancer Immunology, Immunotherapy

Volumn 57, Issue 12, 2008, Pages 1879-1890

  Schmidt, Michael M ^a   Thurber, Greg M ^a   Wittrup, K Dane ^a  

^a Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

Affinity; Antibody fragments; CEA; Endocytosis; Tumor targeting

Indexed keywords

CARCINOEMBRYONIC ANTIBODY; CARCINOEMBRYONIC ANTIGEN; PROTEINASE;

ANTIBODY AFFINITY; ANTIGEN BINDING; ARTICLE; ENDOCYTOSIS; ENZYME METABOLISM; HALF LIFE TIME; HUMAN; HUMAN CELL; INTERNALIZATION; METABOLIC RATE; PRIORITY JOURNAL; TUMOR SPHEROID;

ANTIBODIES; ANTIBODY AFFINITY; CARCINOEMBRYONIC ANTIGEN; CELL LINE; HUMANS; IMMUNOGLOBULIN FRAGMENTS;

EID: 52549121490     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00262-008-0518-1     Document Type: Article

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