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Volumn 14, Issue 1, 1999, Pages 37-47

Carcinoembryonic antigen as a target for radioimmunotherapy of human medullary thyroid carcinoma: Antibody processing, targeting, and experimental therapy with 131I and 90Y labeled MAbs

Author keywords

Animal model; Carcinoembryonic antigen; Medullary thyroid carcinoma; Monoclonal antibodies; Radioimmunotherapy

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; IODINE 131; MONOCLONAL ANTIBODY; YTTRIUM 90;

EID: 0032930201     PISSN: 10849785     EISSN: None     Source Type: Journal    
DOI: 10.1089/cbr.1999.14.37     Document Type: Article
Times cited : (38)

References (37)
  • 1
    • 0003150515 scopus 로고
    • Cancer of the endocrine system
    • DeVita VT, Hellman S, Rosenberg SA, eds. New York: J.B. Lippincott Co.
    • Norton JA, Levin B, Jensen R. Cancer of the endocrine system. In: DeVita VT, Hellman S, Rosenberg SA, eds. Cancer: Principles and practice of oncology. New York: J.B. Lippincott Co., 1989:1333-1435.
    • (1989) Cancer: Principles and Practice of Oncology , pp. 1333-1435
    • Norton, J.A.1    Levin, B.2    Jensen, R.3
  • 2
    • 0022054926 scopus 로고
    • Multiple endocrine neoplasia type IIa
    • Cance WG, Wells SAJ. Multiple endocrine neoplasia type IIa. Curr Prob Surg 1985; 22:1-56.
    • (1985) Curr Prob Surg , vol.22 , pp. 1-56
    • Cance, W.G.1    Wells, S.A.J.2
  • 4
    • 0023814245 scopus 로고
    • Medullary thyroid carcinoma: Prognosis of familial versus sporadic disease and the role of radiotherapy
    • Samaan NA, Schultz PN, Hickey RC. Medullary thyroid carcinoma: prognosis of familial versus sporadic disease and the role of radiotherapy. J Clin Endocrin Metab 1988; 67:801-808.
    • (1988) J Clin Endocrin Metab , vol.67 , pp. 801-808
    • Samaan, N.A.1    Schultz, P.N.2    Hickey, R.C.3
  • 5
    • 0023860752 scopus 로고
    • Prognostic factors in medullary thyroid carcinomas. Survival in relation to age, sex, stage, histology, immunocytochemistry and DNA content
    • Schröder S, Böcker W, Baisch H, et al. Prognostic factors in medullary thyroid carcinomas. Survival in relation to age, sex, stage, histology, immunocytochemistry and DNA content. Cancer 1988; 61:806-816.
    • (1988) Cancer , vol.61 , pp. 806-816
    • Schröder, S.1    Böcker, W.2    Baisch, H.3
  • 6
    • 0018875062 scopus 로고
    • External irradiation for malignant thyroid tumors
    • Chung CT, Sagerman RH, Ryoo MC, et al. External irradiation for malignant thyroid tumors. Radiol 1980; 136:753-756.
    • (1980) Radiol , vol.136 , pp. 753-756
    • Chung, C.T.1    Sagerman, R.H.2    Ryoo, M.C.3
  • 8
    • 0029892932 scopus 로고    scopus 로고
    • Clinical evaluation of tumor targeting with the anti-CEA murine monoclonal antibody fragment I-MN-14 F(ab)2
    • Juweid M, Sharkey RM, Behr T, et al. Clinical evaluation of tumor targeting with the anti-CEA murine monoclonal antibody fragment I-MN-14 F(ab)2. Cancer 1996; 78:157-168.
    • (1996) Cancer , vol.78 , pp. 157-168
    • Juweid, M.1    Sharkey, R.M.2    Behr, T.3
  • 9
    • 0030163020 scopus 로고    scopus 로고
    • Radioimmuno-therapy of medullary thyroid carcinoma with I-131-labeled anti-CEA antibodies
    • Juweid M, Sharkey RM, Behr T, et al. Radioimmuno-therapy of medullary thyroid carcinoma with I-131-labeled anti-CEA antibodies. J Nucl Med 1996; 37:905-911.
    • (1996) J Nucl Med , vol.37 , pp. 905-911
    • Juweid, M.1    Sharkey, R.M.2    Behr, T.3
  • 10
    • 12344315241 scopus 로고
    • Targeting and initial radioimmunotherapy of medullary thyroid carcinoma with I-131-labeled monoclonal antibodies to carcinoembryonic antigen
    • Juweid M, Sharkey RM, Behr T, et al. Targeting and initial radioimmunotherapy of medullary thyroid carcinoma with I-131-labeled monoclonal antibodies to carcinoembryonic antigen. Cancer Res 1995; 55:5946s-5951s.
    • (1995) Cancer Res , vol.55
    • Juweid, M.1    Sharkey, R.M.2    Behr, T.3
  • 11
    • 9244257274 scopus 로고    scopus 로고
    • Improved detection of medullary thyroid carcinoma with radio-labeled antibodies to carcinoembryonic antigen
    • Juweid M, Sharkey RM, Behr T, et al. Improved detection of medullary thyroid carcinoma with radio-labeled antibodies to carcinoembryonic antigen. J Clin Oncol 1996; 14:1209-1217.
    • (1996) J Clin Oncol , vol.14 , pp. 1209-1217
    • Juweid, M.1    Sharkey, R.M.2    Behr, T.3
  • 12
    • 0027166186 scopus 로고
    • Radioimmuno-detection of medullary thyroid cancer using a bispecific anti-CEA/anti-indium-DTPA antibody and an indium-111-labeled DTPA dimer
    • Peltier P, Curtet C, Chatal JF, et al. Radioimmuno-detection of medullary thyroid cancer using a bispecific anti-CEA/anti-indium-DTPA antibody and an indium-111-labeled DTPA dimer. J Nucl Med 1993; 34:1267-1273.
    • (1993) J Nucl Med , vol.34 , pp. 1267-1273
    • Peltier, P.1    Curtet, C.2    Chatal, J.F.3
  • 15
    • 0003405336 scopus 로고
    • Rockville, MD: American Type Culture Collection
    • American Type Culture Collection. ATCC Cell Lines and Hybridomas. Rockville, MD: American Type Culture Collection, 1994:p. 174.
    • (1994) ATCC Cell Lines and Hybridomas , pp. 174
  • 16
    • 0027198722 scopus 로고
    • Characterization of second-generation monoclonal antibodies against carcinoembryonic antigen
    • Hansen HJ, Goldenberg DM, Newman ES, Grebenau R, Sharkey RM. Characterization of second-generation monoclonal antibodies against carcinoembryonic antigen. Cancer 1993; 71:3478-3485.
    • (1993) Cancer , vol.71 , pp. 3478-3485
    • Hansen, H.J.1    Goldenberg, D.M.2    Newman, E.S.3    Grebenau, R.4    Sharkey, R.M.5
  • 18
    • 0025022478 scopus 로고
    • Murine monoclonal antibodies raised: Against human non-small cell carcinoma of the lung: Specificity and tumor targeting
    • Stein R, Chen S, Sharkey RM, Goldenberg DM. Murine monoclonal antibodies raised: against human non-small cell carcinoma of the lung: specificity and tumor targeting. Cancer Res 1990; 50:1330-1336.
    • (1990) Cancer Res , vol.50 , pp. 1330-1336
    • Stein, R.1    Chen, S.2    Sharkey, R.M.3    Goldenberg, D.M.4
  • 19
    • 0028012632 scopus 로고
    • Phase I clinical evaluation of a new murine monoclonal antibody (Mu-9) against colon-specific antigen-p for targeting gastrointestinal carcinomas
    • Sharkey RM, Goldenberg DM, Vagg R, et al. Phase I clinical evaluation of a new murine monoclonal antibody (Mu-9) against colon-specific antigen-p for targeting gastrointestinal carcinomas. Cancer 1994; 73:864-877.
    • (1994) Cancer , vol.73 , pp. 864-877
    • Sharkey, R.M.1    Goldenberg, D.M.2    Vagg, R.3
  • 20
    • 0013867981 scopus 로고
    • A method of trace iodination of proteins for immunologie studies
    • McConahey PJ, Dixon FJ. A method of trace iodination of proteins for immunologie studies. Int Arch Allergy 1966; 29:185-189.
    • (1966) Int Arch Allergy , vol.29 , pp. 185-189
    • McConahey, P.J.1    Dixon, F.J.2
  • 21
    • 0025109434 scopus 로고
    • Metabolism of indium-111-labeled murine monoclonal antibody in tumor and normal tissue of the athymic mouse
    • Motta-Hennessy C, Sharkey RM, Goldenberg DM. Metabolism of indium-111-labeled murine monoclonal antibody in tumor and normal tissue of the athymic mouse. J Nucl Med 1990; 31:1510-1519.
    • (1990) J Nucl Med , vol.31 , pp. 1510-1519
    • Motta-Hennessy, C.1    Sharkey, R.M.2    Goldenberg, D.M.3
  • 22
    • 0026161977 scopus 로고
    • A convenient synthesis of bifunctional chelating agents based on diethylenetriaminepentaacetic acid and their coordination chemistry with yttrium (III)
    • Cummins CH, Rutter EWJ, Fordyce WA. A convenient synthesis of bifunctional chelating agents based on diethylenetriaminepentaacetic acid and their coordination chemistry with yttrium (III). Bioconj Chem 1991; 2:180-186.
    • (1991) Bioconj Chem , vol.2 , pp. 180-186
    • Cummins, C.H.1    Rutter, E.W.J.2    Fordyce, W.A.3
  • 23
    • 0022968394 scopus 로고
    • Synthesis of 1-(p-isothiocyanatobenzyl) derivatives of DTPA and EDTA; antibody labeling and tumor-imaging studies
    • Brechbiel MW, Gansow OA, Atcher RW, et al. Synthesis of 1-(p-isothiocyanatobenzyl) derivatives of DTPA and EDTA; antibody labeling and tumor-imaging studies. Inorg Chem 1986; 25:2772-2781.
    • (1986) Inorg Chem , vol.25 , pp. 2772-2781
    • Brechbiel, M.W.1    Gansow, O.A.2    Atcher, R.W.3
  • 24
    • 0021512252 scopus 로고
    • Conjugation of antibodies with bifunctional chelating agents: Isothiocyanate and bromoacetamide reagents, methods of analysis, and subsequent addition of metal ions
    • Meares CF, McCall MJ, Reardan DT, Goodwin DA, Diamanti CI, McTigue M. Conjugation of antibodies with bifunctional chelating agents: isothiocyanate and bromoacetamide reagents, methods of analysis, and subsequent addition of metal ions. Anal Biochem 1984; 142:68-78.
    • (1984) Anal Biochem , vol.142 , pp. 68-78
    • Meares, C.F.1    McCall, M.J.2    Reardan, D.T.3    Goodwin, D.A.4    Diamanti, C.I.5    McTigue, M.6
  • 25
    • 0024528006 scopus 로고
    • Human lung carcinoma monoclonal antibody specific for the Thomsen-Friedenreich antigen
    • Stein R, Chen S, Grossman W, Goldenberg DM. Human lung carcinoma monoclonal antibody specific for the Thomsen-Friedenreich antigen. Cancer Res 1989; 49:32-37.
    • (1989) Cancer Res , vol.49 , pp. 32-37
    • Stein, R.1    Chen, S.2    Grossman, W.3    Goldenberg, D.M.4
  • 26
    • 0024311902 scopus 로고
    • Penetration and binding of antibodies in experimental and solid tumors
    • Ong GL, Mattes MJ. Penetration and binding of antibodies in experimental and solid tumors. Cancer Res 1989; 49:4264-4273.
    • (1989) Cancer Res , vol.49 , pp. 4264-4273
    • Ong, G.L.1    Mattes, M.J.2
  • 27
    • 0029058307 scopus 로고
    • Effects of radiolabeling monoclonal antibodies with a residualizing iodine radiolabel on the accretion of radioisotope in tumors
    • Stein R, Goldenberg DM, Thorpe SR, Mattes MJ. Effects of radiolabeling monoclonal antibodies with a residualizing iodine radiolabel on the accretion of radioisotope in tumors. Cancer Res 1995; 55:3132-3193.
    • (1995) Cancer Res , vol.55 , pp. 3132-3193
    • Stein, R.1    Goldenberg, D.M.2    Thorpe, S.R.3    Mattes, M.J.4
  • 28
    • 0028117154 scopus 로고
    • Processing of antibody-radioisotope conjugates after binding to the surface of tumor cells
    • Mattes MJ, Griffiths GL, Diril H, Goldenberg DM, Ong GL, Shih LB. Processing of antibody-radioisotope conjugates after binding to the surface of tumor cells. Cancer 1994; 73:787-793.
    • (1994) Cancer , vol.73 , pp. 787-793
    • Mattes, M.J.1    Griffiths, G.L.2    Diril, H.3    Goldenberg, D.M.4    Ong, G.L.5    Shih, L.B.6
  • 29
    • 8944262198 scopus 로고    scopus 로고
    • Processing of antibodies bound to B-cell lymphomas and other hematologic malignancies
    • Hanna R, Ong GL, Mattes MJ. Processing of antibodies bound to B-cell lymphomas and other hematologic malignancies. Cancer Res 1996; 56:3062-3068.
    • (1996) Cancer Res , vol.56 , pp. 3062-3068
    • Hanna, R.1    Ong, G.L.2    Mattes, M.J.3
  • 30
    • 0030883054 scopus 로고    scopus 로고
    • Advantage of a residualizing iodine radiolabel for radioimmunotherapy of xenografts of human non-small cell carcinoma of the lung
    • Stein R, Goldenberg DM, Thorpe SR, Mattes MJ. Advantage of a residualizing iodine radiolabel for radioimmunotherapy of xenografts of human non-small cell carcinoma of the lung. J Nucl Med 1997; 38:391-395.
    • (1997) J Nucl Med , vol.38 , pp. 391-395
    • Stein, R.1    Goldenberg, D.M.2    Thorpe, S.R.3    Mattes, M.J.4
  • 32
    • 0024414831 scopus 로고
    • Comparison of therapeutic efficacy and host toxicity of two different 131I-labelled antibodies and their fragments in the GW-39 colonic cancer xenograft model
    • Blumenthal RD, Sharkey RM, Kashi R, Goldenberg DM. Comparison of therapeutic efficacy and host toxicity of two different 131I-labelled antibodies and their fragments in the GW-39 colonic cancer xenograft model. Int J Cancer 1989; 44:292-300.
    • (1989) Int J Cancer , vol.44 , pp. 292-300
    • Blumenthal, R.D.1    Sharkey, R.M.2    Kashi, R.3    Goldenberg, D.M.4
  • 33
    • 0028786364 scopus 로고
    • Evaluation of a CDR-grafted (humanized) anti-carcinoembryonic antigen (CEA) monoclonal antibody in preclinical and clinical studies
    • Sharkey RM, Juweid M, Shevitz J, et al. Evaluation of a CDR-grafted (humanized) anti-carcinoembryonic antigen (CEA) monoclonal antibody in preclinical and clinical studies. Cancer Res 1995; 55:5935s-5945s.
    • (1995) Cancer Res , vol.55
    • Sharkey, R.M.1    Juweid, M.2    Shevitz, J.3
  • 34
    • 14444275786 scopus 로고    scopus 로고
    • Improved treatment of medullary thyroid cancer in a nude mouse model by combined radioimmunochemotherapy: Doxorubicin potentiates the therapeutic efficacy of radiolabeled antibodies in a radioresistant tumor type
    • Behr TM, Wulst E, Radetzky S, et al. Improved treatment of medullary thyroid cancer in a nude mouse model by combined radioimmunochemotherapy: doxorubicin potentiates the therapeutic efficacy of radiolabeled antibodies in a radioresistant tumor type. Cancer Res 1997; 57:5309-5319.
    • (1997) Cancer Res , vol.57 , pp. 5309-5319
    • Behr, T.M.1    Wulst, E.2    Radetzky, S.3
  • 35
    • 0025234357 scopus 로고
    • Biodistribution and radiation dose estimates for yttrium-and iodine-labeled monoclonal antibody IgG and fragments in nude mice bearing human colonic tumor xenografts
    • Sharkey RM, Motta-Hennessy C, Pawlyk D, Siegal JA, Goldenberg DM. Biodistribution and radiation dose estimates for yttrium-and iodine-labeled monoclonal antibody IgG and fragments in nude mice bearing human colonic tumor xenografts. Cancer Res 1990; 50:2330-2336.
    • (1990) Cancer Res , vol.50 , pp. 2330-2336
    • Sharkey, R.M.1    Motta-Hennessy, C.2    Pawlyk, D.3    Siegal, J.A.4    Goldenberg, D.M.5
  • 36
    • 0031457988 scopus 로고    scopus 로고
    • Advantage of 90Y-over 131I-labeled monoclonal antibodies in the therapy of a human lung cancer xenograft
    • Stein R, Chen S, Haim S, Goldenberg DM. Advantage of 90Y-over 131I-labeled monoclonal antibodies in the therapy of a human lung cancer xenograft. Cancer 1997; 80:2636-2641.
    • (1997) Cancer , vol.80 , pp. 2636-2641
    • Stein, R.1    Chen, S.2    Haim, S.3    Goldenberg, D.M.4
  • 37
    • 0030739164 scopus 로고    scopus 로고
    • Selection of radioimmunoconjugates for the therapy of well-established or micrometastatic colon cancer
    • Sharkey RM, Blumenthal RD, Behr TM, et al. Selection of radioimmunoconjugates for the therapy of well-established or micrometastatic colon cancer. Int J Cancer 1997; 73:477-485.
    • (1997) Int J Cancer , vol.73 , pp. 477-485
    • Sharkey, R.M.1    Blumenthal, R.D.2    Behr, T.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.