Dysfunction of pulmonary vascular endothelium in chronic obstructive pulmonary disease: Basic considerations for future drug development

Current Drug Metabolism

Volumn 9, Issue 7, 2008, Pages 661-667

  Yang, Qin ^a   Underwood, Malcolm J ^a   Hsin, Michael K Y ^a   Liu, Xiao Cheng ^b   He, Guo Wei ^a,b,c,d  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b NANKAI UNIVERSITY   (China)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Adhesion molecules; Chronic obstructive pulmonary disease; Endothelium derived relaxing factors; Pulmonary endothelium; Vascular progenitor cells; VEGF

Indexed keywords

AZITHROMYCIN; CELL ADHESION MOLECULE; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; ENDOTHELIUM DERIVED RELAXING FACTOR; GROWTH FACTOR; NITRIC OXIDE; PROSTACYCLIN; SELECTIN; THROMBOMODULIN; TISSUE FACTOR PATHWAY INHIBITOR; VASCULOTROPIN; XENOBIOTIC AGENT;

ANTICOAGULATION; APOPTOSIS; CELL STRUCTURE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CIGARETTE SMOKING; DISEASE ASSOCIATION; DISEASE COURSE; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENDOTHELIUM INJURY; ERYTHROCYTE; HEMATOPOIETIC STEM CELL; HUMAN; HYPOXIA; INFLAMMATORY CELL; LUNG BLOOD VESSEL; LUNG ENDOTHELIUM; OXIDATIVE STRESS; PATHOGENESIS; PROTEIN EXPRESSION; REVIEW; RISK FACTOR; SMOOTH MUSCLE FIBER; THROMBOCYTE AGGREGATION; TISSUE REGENERATION; TISSUE REPAIR; UPREGULATION; VASOCONSTRICTION; VASODILATATION;

ANIMALS; DRUG DESIGN; ENDOTHELIAL CELLS; HUMANS; LUNG; MYOCYTES, SMOOTH MUSCLE; OXIDATIVE STRESS; PLATELET AGGREGATION; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SMOKING; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASOCONSTRICTION;

EID: 52449133912     PISSN: 13892002     EISSN: None     Source Type: Journal    
DOI: 10.2174/138920008785821684     Document Type: Review

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