Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 295, Issue 2, 2008, Pages

  Dayal, Sanjana ^a   Rodionov, Roman N ^a   Arning, Erland ^b   Bottiglieri, Teodoro ^b   Kimoto, Masumi ^c   Murry, Daryl J ^d   Cooke, John P ^e   Faraci, Frank M ^a   Lentz, Steven R ^a,f  

^a UNIVERSITY OF IOWA   (United States)

^b BAYLOR UNIVERSITY MEDICAL CENTER   (United States)

^c OKAYAMA PREFECTURAL UNIVERSITY   (Japan)

^d UNIVERSITY OF IOWA   (United States)

^e STANFORD UNIVERSITY   (United States)

^f VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Asymmetric dimethylarginine; Endothelium; Homocysteine; Vascular function

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; ACETYLCHOLINE; CYSTATHIONINE BETA SYNTHASE; DIMETHYLARGININASE; FOLIC ACID; HOMOCYSTEINE; MESSENGER RNA; METHIONINE; N(G),N(G) DIMETHYLARGININE; NITRIC OXIDE SYNTHASE INHIBITOR; NITROPRUSSIDE SODIUM; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE; AMIDASE; ARGININE; DRUG DERIVATIVE; N,N DIMETHYLARGININE; N,N' DIMETHYLARGININE; N,N'-DIMETHYLARGININE; N,N-DIMETHYLARGININE; NITRIC OXIDE; VASODILATOR AGENT;

ANIMAL CELL; ARTICLE; CAROTID ARTERY; CONTROLLED STUDY; DDAH1 GENE; DDAH2 GENE; DIETARY INTAKE; ENDOTHELIUM CELL; ENDOTHELIUM LESION; ENZYME REGULATION; GENE; GENE EXPRESSION REGULATION; HYPERHOMOCYSTEINEMIA; IN VITRO STUDY; IN VIVO STUDY; KIDNEY PARENCHYMA; LIVER PARENCHYMA; LUNG PARENCHYMA; METHYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE SPECIFICITY; VASCULAR DISEASE; VASODILATATION; ANIMAL; BLOOD; C57BL MOUSE; CELL LINE; DISEASE MODEL; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECT; ENZYMOLOGY; GENETICS; LIVER; METABOLISM; MOUSE MUTANT; PATHOPHYSIOLOGY; VASCULAR ENDOTHELIUM;

AMIDOHYDROLASES; ANIMALS; ARGININE; CAROTID ARTERIES; CELL LINE; CYSTATHIONINE BETA-SYNTHASE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; FOLIC ACID; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HOMOCYSTEINE; HYPERHOMOCYSTEINEMIA; LIVER; METHIONINE; METHYLATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NITRIC OXIDE; RNA, MESSENGER; VASODILATION; VASODILATOR AGENTS;

EID: 52449130126     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01348.2007     Document Type: Article

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