Mechanism of dietary salt-mediated increase in intravascular production of TGF-β1

American Journal of Physiology - Renal Physiology

Volumn 295, Issue 2, 2008, Pages

  Ying, Wei Zhong ^a   Aaron, Kristal ^a   Sanders, Paul W ^a,b,c  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c BIRMINGHAM VA MEDICAL CENTER   (United States)

Author keywords

Aorta; C Src; Endothelium; Glomerulus; Proline rich tyrosine kinase 2

Indexed keywords

FOCAL ADHESION KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE P60; TRANSFORMING GROWTH FACTOR BETA1; TYRPHOSTIN; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE C SRC; PROTEIN-TYROSINE KINASE C-SRC;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; GLOMERULUS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RAT; SALT INTAKE; VASCULAR RING; VASCULARIZATION; ANIMAL; AORTA; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; SODIUM INTAKE; SPRAGUE DAWLEY RAT; VASCULAR ENDOTHELIUM;

ANIMALS; AORTA; ENDOTHELIUM, VASCULAR; FOCAL ADHESION KINASE 2; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN-TYROSINE KINASES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SODIUM, DIETARY; TRANSFORMING GROWTH FACTOR BETA1;

EID: 52449128009     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.90294.2008     Document Type: Article

References (45)

1. Abe M, Harpel JG, Metz CN, Nunes I, Loskutoff DJ, Rifkin DB. An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct. Anal Biochem 216: 276-284, 1994.
2. Avraham H, Park SY, Schinkmann K, Avraham S. RAFTK/Pyk2-mediated cellular signalling. Cell Signal 12: 123-133, 2000.
3. Avraham S, London R, Fu Y, Ota S, Hiregowdara D, Li J, Jiang S, Pasztor LM, White RA, Groopman JE, Avraham H. Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain. J Biol Chem 270: 27742-27751, 1995.
4. Becker-Hapak M, McAllister SS, Dowdy SF. TAT-mediated protein transduction into mammalian cells. Methods 24: 247-256, 2001.
5. Benstein JA, Feiner HD, Parker M, Dworkin LD. Superiority of salt restriction over diuretics in reducing renal hypertrophy and injury in uninephrectomized SHR. Am J Physiol Renal Fluid Electrolyte Physiol 258: F1675-F1681, 1990.
6. Blaukat A, Ivankovic-Dikic I, Gronroos E, Dolfi F, Tokiwa G, Vuori K, Dikic I. Adaptor proteins Grb2 and Crk couple Pyk2 with activation of specific mitogen-activated protein kinase cascades. J Biol Chem 274: 14893-14901, 1999.
7. Border WA, Okuda S, Languino LR, Sporn MB, Ruoslahti E. Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1. Nature 346: 371-374, 1990.
8. Chen S, Sega M, Agarwal A. "Lumen digestion" technique for isolation of aortic endothelial cells from heme oxygenase-1 knockout mice. Biotechniques 37: 84-86, 88-89, 2004.
9. Cianciaruso B, Bellizzi V, Minutolo R, Tavera A, Capuano A, Conte G, De Nicola L. Salt intake and renal outcome in patients with progressive renal disease. Miner Electrolyte Metab 24: 296-301, 1998.
10. Cook NR, Cutler JA, Obarzanek E, Buring JE, Rexrode KM, Kumanyika SK, Appel LJ, Whelton PK. Long term effects of dietary sodium reduction on cardiovascular disease outcomes: observational follow-up of the trials of hypertension prevention (TOHP). BMJ 334: 885, 2007.
11. Davies PF. Multiple signaling pathways in flow-mediated endothelial mechanotransduction: PYK-ing the right location. Arterioscler Thromb Vasc Biol 22: 1755-1757, 2002.
12. Dikic I, Tokiwa G, Lev S, Courtneidge SA, Schlessinger J. A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation. Nature 383: 547-550, 1996.
13. Fesler P, Safar ME, du Cailar G, Ribstein J, Mimran A. Pulse pressure is an independent determinant of renal function decline during treatment of essential hypertension. J Hypertens 25: 1915-1920, 2007.
14. Fuortes M, Melchior M, Han H, Lyon GJ, Nathan C. Role of the tyrosine kinase pyk2 in the integrin-dependent activation of human neutrophils by TNF. J Clin Invest 104: 327-335, 1999.
15. Gates PE, Tanaka H, Hiatt WR, Seals DR. Dietary sodium restriction rapidly improves large elastic artery compliance in older adults with systolic hypertension. Hypertension 44: 35-41, 2004.
16. Gibbons GH, Pratt RE, Dzau VJ. Vascular smooth muscle cell hypertrophy vs. hyperplasia Autocrine transforming growth factor-β1 expression determines growth response to angiotensin II. J Clin Invest 90: 456-461, 1992.
17. Han H, Fuortes M, Nathan C. Critical role of the carboxyl terminus of proline-rich tyrosine kinase (Pyk2) in the activation of human neutrophils by tumor necrosis factor: separation of signals for the respiratory burst and degranulation. J Exp Med 197: 63-75, 2003.
18. Hanke JH, Gardner JP, Dow RL, Changelian PS, Brissette WH, Weringer EJ, Pollok BA, Connelly PA. Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation. J Biol Chem 271: 695-701, 1996.
19. Hunter T. Treatment for chronic myelogenous leukemia: the long road to imatinib. J Clin Invest 117: 2036-2043, 2007.
20. Klag MJ, Whelton PK, Randall BL, Neaton JD, Brancati FL, Ford CE, Shulman NB, Stamler J. Blood pressure and end-stage renal disease in men. N Engl J Med 334: 13-18, 1996.
21. 2+/calmodulin to FERM F2 alpha2 helix and thus forming its dimer. Biochem J 410: 513-523, 2008.
22. 2+-induced regulation of ion channel and MAP kinase functions. Nature 376: 737-745, 1995.
23. Li X, Dy RC, Cance WG, Graves LM, Earp HS. Interactions between two cytoskeleton-associated tyrosine kinases: calcium-dependent tyrosine kinase and focal adhesion tyrosine kinase. J Biol Chem 274: 8917-8924, 1999.
24. McMullen M, Keller R, Sussman M, Pumiglia K. Vascular endothelial growth factor-mediated activation of p38 is dependent upon Src and RAFTK/Pyk2. Oncogene 23: 1275-1282, 2004.
25. Meneely GR, Ball CO. Experimental epidemiology of chronic sodium chloride toxicity and the protective effect of potassium chloride. Am J Med 25: 713-725, 1958.
26. Meneely GR, Tucker RG, Darby WJ, Auerbach SH. Chronic sodium chloride toxicity: hypertension, renal failure and vascular lesions. Ann Intern Med 39: 991-998, 1953.
27. Mozes MM, Bottinger EP, Jacot TA, Kopp JB. Renal expression of fibrotic matrix proteins and of transforming growth factor-beta (TGF-beta) isoforms in TGF-beta transgenic mice. J Am Soc Nephrol 10: 271-280, 1999.
28. Nagahara H, Vocero-Akbani AM, Snyder EL, Ho A, Latham DG, Lissy NA, Becker-Hapak M, Ezhevsky SA, Dowdy SF. Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration. Nat Med 4: 1449-1452, 1998.
29. Pandey P, Avraham S, Kumar S, Nakazawa A, Place A, Ghanem L, Rana A, Kumar V, Majumder PK, Avraham H, Davis RJ, Kharbanda S. Activation of p38 mitogen-activated protein kinase by PYK2/related adhesion focal tyrosine kinase-dependent mechanism. J Biol Chem 274: 10140-10144, 1999.
30. Ruiz-Ortega M, Rodriguez-Vita J, Sanchez-Lopez E, Carvajal G, Egido J. TGF-beta signaling in vascular fibrosis. Cardiovasc Res 74: 196-206, 2007.
31. Sanders PW, Gibbs CL, Akhi KM, MacMillan-Crow LA, Zinn KR, Chen YF, Young CJ, Thompson JA. Increased dietary salt accelerates chronic allograft nephropathy in rats. Kidney Int 59: 1149-1157, 2001.
32. Schiffrin EL. Vascular stiffening and arterial compliance. Implications for systolic blood pressure. Am J Hypertens 17: 39S-48S, 2004.
33. Tahara S, Fukuda K, Kodama H, Kato T, Miyoshi S, Ogawa S. Potassium channel blocker activates extracellular signal-regulated kinases through Pyk2 and epidermal growth factor receptor in rat cardiomyocytes. J Am Coll Cardiol 38: 1554-1563, 2001.
34. Tai LK, Okuda M, Abe J, Yan C, Berk BC. Fluid shear stress activates proline-rich tyrosine kinase via reactive oxygen species-dependent pathway. Arterioscler Thromb Vasc Biol 22: 1790-1796, 2002.
35. Weir MR, Dworkin LD. Antihypertensive drugs, dietary salt, and renal protection: how low should you go and with which therapy? Am J Kidney Dis 32: 1-22, 1998.
36. Wynn TA. Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases. J Clin Invest 117: 524-529, 2007.
37. Ying WZ, Sanders PW. Dietary salt enhances glomerular endothelial nitric oxide synthase through TGF-β1. Am J Physiol Renal Physiol 275: F18-F24, 1998.
38. Ying WZ, Sanders PW. Dietary salt increases endothelial nitric oxide synthase and TGF-β1 in rat aortic endothelium. Am J Physiol Heart Circ Physiol 277: H1293-H1298, 1999.
39. Ying WZ, Sanders PW. Dietary salt intake activates MAP kinases in the rat kidney. FASEB J 16: 1683-1684, 2002.
40. Ying WZ, Sanders PW. Dietary salt modulates renal production of transforming growth factor-β in rats. Am J Physiol Renal Physiol 274: F635-F641, 1998.
41. Ying WZ, Sanders PW. Increased dietary salt activates rat aortic endothelium. Hypertension 39: 239-244, 2002.
42. Ying WZ, Sanders PW. The interrelationship between TGF-β1 and nitric oxide is altered in salt-sensitive hypertension. Am J Physiol Renal Physiol 285: F902-F908, 2003.
43. Yu H, Li X, Marchetto GS, Dy R, Hunter D, Calvo B, Dawson TL, Wilm M, Anderegg RJ, Graves LM, Earp HS. Activation of a novel calcium-dependent protein-tyrosine kinase. Correlation with c-Jun N-terminal kinase but not mitogen-activated protein kinase activation. J Biol Chem 271: 29993-29998, 1996.
44. Yu HCM, Burrell LM, Black MJ, Wu LL, Dilley RJ, Cooper ME, Johnston CI. Salt induces myocardial and renal fibrosis in normotensive and hypertensive rats. Circulation 98: 2621-2628, 1998.
45. Zacchigna L, Vecchione C, Notte A, Cordenonsi M, Dupont S, Maretto S, Cifelli G, Ferrari A, Maffei A, Fabbro C, Braghetta P, Marino G, Selvetella G, Aretini A, Colonnese C, Bettarini U, Russo G, Soligo S, Adorno M, Bonaldo P, Volpin D, Piccolo S, Lembo G, Bressan GM. Emilin1 links TGF-beta maturation to blood pressure homeostasis. Cell 124: 929 -942, 2006.