AP-1 DNA binding activity regulates the cartilage tissue remodeling process following cyclic compression in vitro

Biorheology

Volumn 45, Issue 3-4, 2008, Pages 459-469

  De Croos, J N A ^a   Pilliar, R M ^a,b   Kandel, R A ^a,b  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Chondrocytes; Decoy oligodeoxynucleotides; Mechanical stimulation; Tissue engineering

Indexed keywords

BINDING PROTEIN; COLLAGENASE 3; OLIGODEOXYNUCLEOTIDE DERIVATIVE; PROTEIN AP 1; PROTEOGLYCAN; STROMELYSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; BINDING AFFINITY; BIOACCUMULATION; BIOSYNTHESIS; CARTILAGE CELL; CATABOLISM; CONFERENCE PAPER; CONTROLLED STUDY; DNA BINDING; EXTRACELLULAR MATRIX; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; MECHANICAL STIMULATION; NONHUMAN; TISSUE ENGINEERING;

ANIMALS; BINDING SITES; CARTILAGE; CATTLE; CHONDROCYTES; COLLAGEN; COMPRESSIVE STRENGTH; DNA; EXTRACELLULAR MATRIX; MATRIX METALLOPROTEINASE 13; MATRIX METALLOPROTEINASE 3; OLIGODEOXYRIBONUCLEOTIDES; PROTEOGLYCANS; TISSUE ENGINEERING; TRANSCRIPTION FACTOR AP-1;

EID: 52449113790     PISSN: 0006355X     EISSN: None     Source Type: Journal    
DOI: 10.3233/BIR-2008-0488     Document Type: Conference Paper

References (40)

1. U. Benbow and C.E. Brinckerhoff, The AP-1 site and MMP gene regulation: what is all the fuss about?, Matrix Biol. 15 (1997), 519-526.
2. B.L. Bennett, D.T. Sasaki, B.W. Murray, E.C. O'Leary, S.T. Sakata, W. Xu, J.C. Leisten, A. Motiwala, S. Pierce, Y. Satoh, S.S. Bhagwat, A.M. Manning and D.W. Anderson, SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase, Proc. Natl. Acad. Sci. USA 98 (2001), 13681-13686.
3. A. Bielinska, R.A. Shivdasani, L.Q. Zhang and G.J. Nabel, Regulation of gene expression with double-stranded phosphorothioate oligonucleotides, Science 250 (1990), 997-1000.
4. R.C. Borghaei, P.L. Rawlings Jr., M. Javadi and J. Woloshin, NF-kappaB binds to a polymorphic repressor element in the MMP-3 promoter, Biochem. Biophys. Res. Commun. 316 (2004), 182-188.
5. J. Boyle, B. Luan, T.F. Cruz and R.A. Kandel, Characterization of proteoglycan accumulation during formation of cartilagenous tissue in vitro, Osteoarthr. Cartilage 3 (1995), 117-125.
6. M.D. Buschmann, Y.A. Gluzband, A.J. Grodzinsky and E.B. Hunziker, Mechanical compression modulates matrix biosynthesis in chondrocyte/agarose culture, J. Cell Sci. 108(Pt 4) (1995), 1497-1508.
7. M.D. Buschmann, Y.A. Gluzband, A.J. Grodzinsky, J.H. Kimura and E.B. Hunziker, Chondrocytes in agarose culture synthesize a mechanically functional extracellular matrix, J. Orthop. Res. 10 (1992), 745-758.
8. S. Chakraborti, M. Mandal, S. Das, A. Mandal and T. Chakraborti, Regulation of matrix metalloproteinases: an overview, Mol. Cell. Biochem. 253 (2003), 269-285.
9. P. Chomczynki, A reagent for the single-step simultaneous isolation of RNA, DNA, and proteins from cell and tissue samples, BioTechniques 15 (1993), 532-537.
10. H.C. Crawford and L.M. Matrisian, Mechanisms controlling the transcription of matrix metalloproteinase genes in normal and neoplastic cells, Enzyme Protein 49 (1996), 20-37.
11. J.N. De Croos, S.S. Dhaliwal, M.D. Grynpas, R.M. Pilliar and R.A. Kandel, Cyclic compressive mechanical stimulation induces sequential catabolic and anabolic gene changes in chondrocytes resulting in increased extracellular matrix accumulation, Matrix Biol. 25 (2006), 323-331.
12. P.J. Fanning, G. Emkey, R.J. Smith, A.J. Grodzinsky, N. Szasz and S.B. Trippel, Mechanical regulation of mitogen-activated protein kinase signaling in articular cartilage, J. Biol. Chem. 278 (2003), 50940-50948.
13. A. Fehrenbacher, E. Steck, M. Rickert, W. Roth and W. Richter, Rapid regulation of collagen but not metalloproteinase 1, 3, 13, 14 and tissue inhibitor of metalloproteinase 1, 2, 3 expression in response to mechanical loading of cartilage explants in vitro, Arch. Biochem. Biophys. 410 (2003), 39-47.
14. M.J. Filiaggi, J.D. Wells, S.A.F. Peel, R.M. Pilliar, M.D. Grynpas and R.A. Kandel, Condensed calcium phosphates for soft tissue and bone repair/regeneration, Bioceramics 11 (1998), 341-344.
15. J.B. Fitzgerald, M. Jin, D. Dean, D.J. Wood, M.H. Zheng and A.J. Grodzinsky, Mechanical compression of cartilage explants induces multiple time-dependent gene expression patterns and involves intracellular calcium and cyclic AMP, J. Biol. Chem. 279 (2004), 19502-19511.
16. C. Gendron, M. Kashiwagi, N.H. Lim, J.J. Enghild, I.B. Thogersen, C. Hughes, B. Caterson and H. Nagase, Proteolytic activities of human ADAMTS-5: Comparative studies with human ADAMTS-4, J. Biol. Chem. 282 (2007), 18294-18306.
17. H. Hacker, H. Mischak, T. Miethke, S. Liptay, R. Schmid, T. Sparwasser, K. Heeg, G.B. Lipford and H. Wagner, CpGDNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation, EMBO J. 17 (1998), 6230-6240.
18. T. Hai and T. Curran, Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity, Proc. Natl. Acad. Sci. USA 88 (1991), 3720-3724.
19. Y.J. Kim, R.L. Sah, J.Y. Doong and A.J. Grodzinsky, Fluorometric assay of DNA in cartilage explants using Hoechst 33258, Anal. Biochem. 174 (1988), 168-176.
20. A. Kumar, A.J. Knox and A.M. Boriek, CCAAT/enhancer-binding protein and activator protein-1 transcription factors regulate the expression of interleukin-8 through the mitogen-activated protein kinase pathways in response to mechanical stretch of human airway smooth muscle cells, J. Biol. Chem. 278 (2003), 18868-18876.
21. R.L. Mauck, S.B. Nicoll, S.L. Seyhan, G.A. Ateshian and C.T. Hung, Synergistic action of growth factors and dynamic loading for articular cartilage tissue engineering, Tissue Eng. 9 (2003), 597-611.
22. J.A. Mengshol, M.P. Vincenti, C.I. Coon, A. Barchowsky and C.E. Brinckerhoff, Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-Jun N-terminal kinase, and nuclear factor kappaB: differential regulation of collagenase 1 and collagenase 3, Arthrit. Rheum. 43 (2000), 801-811.
23. R. Morishita, M. Aoki and Y. Kaneda, Decoy oligodeoxynucleotides as novel cardiovascular drugs for cardiovascular disease, Ann. N. Y. Acad. Sci. 947 (2001), 294-301.
24. M.A. Peake and A.J. El Haj, Preliminary characterisation of mechanoresponsive regions of the c-fos promoter in bone cells, FEBS Lett. 537 (2003), 117-120.
25. F.A. Peverali, E.K. Basdra and A.G. Papavassiliou, Stretch-mediated activation of selective MAPK subtypes and potentiation of AP-1 binding in human osteoblastic cells, Mol. Med. 7 (2001), 68-78.
26. R.M. Pilliar, M.J. Filiaggi, J.D. Wells, M.D. Grynpas and R.A. Kandel, Porous calcium polyphosphate scaffolds for bone substitute applications - in vitro characterization, Biomaterials 22 (2001), 963-972.
27. A. Ray, K. Kuroki, J.L. Cook, B.S. Bal, K. Kenter, G. Aust and B.K. Ray, Induction of matrix metalloproteinase 1 gene expression is regulated by inflammation-responsive transcription factor SAF-1 in osteoarthritis, Arthrit. Rheum. 48 (2003), 134-145.
28. J.D. Sandy, A contentious issue finds some clarity: on the independent and complementary roles of aggrecanase activity and MMP activity in human joint aggrecanolysis, Osteoarthr. Cartilage 14 (2006), 95-100.
29. T. Smeal, P. Angel, J. Meek and M. Karin, Different requirements for formation of Jun: Jun and Jun: Fos complexes, Genes Dev. 3 (1989), 2091-2100.
30. M. Thibault, A.R. Poole and M.D. Buschmann, Cyclic compression of cartilage/bone explants in vitro leads to physical weakening, mechanical breakdown of collagen and release of matrix fragments, J. Orthop. Res. 20 (2002), 1265-1273.
31. K. Thirunavukkarasu, Y. Pei and T.Wei, Characterization of the human ADAMTS-5 (aggrecanase-2) gene promoter, Mol. Biol. Rep. 34 (2007), 224-231.
32. W.B. Valhmu, G.D. Palmer, J. Dobson, S.G. Fischer and A. Ratcliffe, Regulatory activities of the 5′- and 3′-untranslated regions and promoter of the human aggrecan gene, J. Biol. Chem. 273 (1998), 6196-6202.
33. M. Vikkula, M. Metsaranta, A.C. Syvanen, L. Ala-Kokko, E. Vuorio and L. Peltonen, Structural analysis of the regulatory elements of the type-II procollagen gene. Conservation of promoter and first intron sequences between human and mouse, Biochem. J. 285(Pt 1) (1992), 287-294.
34. M.P. Vincenti and C.E. Brinckerhoff, Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: integration of complex signaling pathways for the recruitment of gene-specific transcription factors, Arthrit. Res. 4 (2002), 157-164.
35. S.D. Waldman, D.C. Couto, M.D. Grynpas, R.M. Pilliar and R.A. Kandel, A single application of cyclic loading can accelerate matrix deposition and enhance the properties of tissue-engineered cartilage, Osteoarthr. Cartilage 14 (2006), 323-330.
36. S.D. Waldman, M.D. Grynpas, R.M. Pilliar and R.A. Kandel, Characterization of cartilagenous tissue formed on calcium polyphosphate substrates in vitro, J. Biomed. Mater. Res. 62 (2002), 323-330.
37. S.D. Waldman, C.G. Spiteri, M.D. Grynpas, R.M. Pilliar, J. Hong and R.A. Kandel, Effect of biomechanical conditioning on cartilaginous tissue formation in vitro, J. Bone Joint Surg. Am. 85-A(Suppl. 2) (2003), 101-105.
38. S.D. Waldman, C.G. Spiteri, M.D. Grynpas, R.M. Pilliar and R.A. Kandel, Long-term intermittent shear deformation improves the quality of cartilaginous tissue formed in vitro, J. Orthop. Res. 21 (2003), 590-596.
39. Z.Werb and J.R. Chin, Extracellular matrix remodeling during morphogenesis, Ann. N. Y. Acad. Sci. 857 (1998), 110-118.
40. J. Westermarck and V.M. Kahari, Regulation of matrix metalloproteinase expression in tumor invasion, FASEB J. 13 (1999), 781-792.