Site-specific drug delivery to the middle region of the small intestine by application of enteric coating with hypromellose acetate succinate (HPMCAS)

Journal of Pharmaceutical Sciences

Volumn 97, Issue 7, 2008, Pages 2665-2679

  Tanno, Fumié K ^a   Sakuma, Shinji ^b   Masaoka, Yoshie ^b   Kataoka, Makoto ^b   Kozaki, Toshio ^c   Kamaguchi, Ryosei ^c   Ikeda, Yutaka ^a   Kokubo, Hiroyasu ^a   Yamashita, Shinji ^b  

^a SHIN ETSU CHEMICAL CO LTD   (Japan)

^b SETSUNAN UNIVERSITY   (Japan)

^c Morishita Jintan Co Ltd   (Japan)

Author keywords

Dissolution; Enteric coating; Gastrointestinal transit; Hypromellose acetate succinate; In vitro in vivo correlations; Intestinal absorption; pH dependent dissolution; Site specific delivery

Indexed keywords

HYPROMELLOSE ACETATE SUCCINATE; SUCCINIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG STRUCTURE; IN VITRO STUDY; NONHUMAN; PH; RAT; SMALL INTESTINE;

EID: 52449086348     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21172     Document Type: Article

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