Methoxy-substituted 9-aminomethyl-9,10-dihydroanthracene (AMDA) derivatives exhibit differential binding affinities at the 5-HT2A receptor

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 19, 2008, Pages 5268-5271

  Dewkar, Gajanan K ^a   Peddi, Srinivas ^a   Mosier, Philip D ^a   Roth, Bryan L ^b   Westkaemper, Richard B ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

5 HT2A; AMDA; Homology model

Indexed keywords

9 AMINOMETHYL 9,10 DIHYDROANTHRACENE; SEROTONIN 2A RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG BINDING SITE; DRUG CONFORMATION; DRUG RECEPTOR BINDING; HYDROGEN BOND; ISOMER; MOLECULAR MODEL; RECEPTOR AFFINITY; STEREOCHEMISTRY;

ANTHRACENES; COMBINATORIAL CHEMISTRY TECHNIQUES; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; RECEPTOR, SEROTONIN, 5-HT2A; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 52249112061     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.08.059     Document Type: Article

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