Apoptosis and necrosis in the ischemic zone adjacent to third degree burns

Academic Emergency Medicine

Volumn 15, Issue 6, 2008, Pages 549-554

  Singer, Adam J ^a   McClain, Steve A ^a   Taira, Breena R ^a   Guerriero, Jennifer L ^b   Zong, Wexing ^b  

^a STONY BROOK UNIVERSITY   (United States)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

Apoptosis; Burns; Conversion; Necrosis

Indexed keywords

CASPASE 3; HIGH MOBILITY GROUP B1 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BURN; CONTROLLED STUDY; DERMIS; DISEASE SEVERITY; EPIDERMIS; HAIR FOLLICLE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; ISCHEMIA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SEBACEOUS GLAND; SKIN FIBROBLAST; TISSUE NECROSIS; ANIMAL; BIOPSY; DISEASE COURSE; DISEASE MODEL; ENZYME IMMUNOASSAY; NECROSIS; PATHOLOGY; PHYSIOLOGY; PILOT STUDY; PROSPECTIVE STUDY; SKIN; SPRAGUE DAWLEY RAT; VASCULARIZATION;

ANIMALS; APOPTOSIS; BIOPSY; BURNS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; IMMUNOENZYME TECHNIQUES; ISCHEMIA; MALE; NECROSIS; PILOT PROJECTS; PROSPECTIVE STUDIES; RATS; RATS, SPRAGUE-DAWLEY; SKIN;

EID: 52149123734     PISSN: 10696563     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1553-2712.2008.00115.x     Document Type: Article

References (21)

1. Jackson DM. The treatment of burns: an exercise in emergency surgery. Ann R Coll Surg Engl. 1953; 13:236-57.
2. Papp A, Kiraly K, Harma M, Lahtinen T, Uusaro A, Alhava E. The progression of burn depth in experimental burns: a histological and methodological study. Burns. 2004; 30:684-90.
3. Singh V, Devgan L, Bhat S, Milner SM. The pathogenesis of burn wound conversion. Ann Plast Surg. 2007; 59:109-15.
4. Iwasaki K, Izawa M, Mihara M. Thermal injury induces both necrosis and apoptosis in rat skin. Br J Dermatol. 1997; 137:647-8.
5. Contassot E, Gaide O, French LE. Death receptors and apoptosis. Dermatol Clin. 2007; 25:487-501.
6. National Academy of Sciences. Guide for the Care and Use of Laboratory Animals. Washington, DC: National Academy Press, 1996.
7. Regas FC, Ehrlich HP. Elucidating the vascular response to burns with a new rat model. J Trauma. 1992; 32:557-63.
8. Choi M, Ehrlich HP. U75412E, a lazaroid, prevents progressive burn ischemia in a rat burn model. Am J Pathol. 1993; 142:519-28.
9. Sun NK, Chao CC. The cytokine activity of HMGB1-extracellular escape of the nuclear protein. Chang Gung Med J. 2005; 28:673-82.
10. Gravante G, Palmieri MB, Esposito G, et al. Apoptotic cells are present in ischemic zones of deep partial-thickness burns. J Burn Care Res. 2006; 27:688-93.
11. Gravante G, Filingeri V, Delogu D, et al. Apoptotic cell death in deep partial thickness burns by coexpression analysis of TUNEL and Fas. Surgery. 2006; 139:854-5.
12. Gravante G, Palmieri MB, Esposito G, et al. Apoptotic death in deep partial thickness burns vs. normal skin of burned patients. J Surg Res. 2007; 141:141-5.
13. Vernez M, Raffoul W, Gailloud-Matthieu MC, et al. Quantitative assessment of cell viability and apoptosis in cultured epidermal autografts: application to burn therapy. Int J Artif Organs. 2003; 26:793-803.
14. Ipaktchi K, Mattar A, Niederbichler AD, et al. Topical p38MAPK inhibition reduces dermal inflammation and epithelial apoptosis in burn wounds. Shock. 2006; 26:201-9.
15. Wu GS. The functional interactions between the p53 and MAPK signaling pathways. Cancer Biol Ther. 2004; 3:156-61.
16. Dillman JF III, McGary KL, Schlager JJ. An inhibitor of p38 MAP kinase downregulates cytokine release induced by sulfur mustard exposure in human epidermal keratinocytes. Toxicol In Vitro. 2004; 18:593-9.
17. Huang C, Ma WY, Maxiner A, Sun Y, Dong Z. p38 kinase mediates UV-induced phosphorylation of p53 protein at serine 389. J Biol Chem. 1999; 274:12229-35.
18. Bernstam L, Nriagu J. Molecular aspects of arsenic stress. J Toxicol Environ Health. 2000; 3:293-322.
19. Jeschke MG, Bolder U, Finnerty CC, et al. The effect of hepatocyte growth factor on gut mucosal apoptosis and proliferation, and cellular mediators after severe trauma. Surgery. 2005; 138:482-9.
20. Johnson SA, Young C, Olney JW. Isoflurane-induced neuroapoptosis in the developing brain of nonhypoglycemic mice. J Neurosurg Anesthesiol. 2008; 20:21-8.
21. Aravindan N, Cata JP, Hoffman L, et al. Effects of isoflurane, pentobarbital, and urethane on apoptosis and apoptotic signal transduction in rat kidney. Acta Anaesthesiol Scand. 2006; 50:1229-37.