DNA with stable fluorinated da and dG substitutes: Syntheses, base pairing and 19F-NMR spectra of 7-fluoro-7-deaza-2′-deoxyadenosine and 7-fluoro-7-deaza-2′-deoxyguanosine

Organic and Biomolecular Chemistry

Volumn 6, Issue 19, 2008, Pages 3552-3560

  Seela, Frank ^a,b   Xu, Kuiying ^a,b  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY OF OSNABRÜCK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; FLUORINE; NUCLEIC ACIDS; NUCLEOTIDES; OLIGONUCLEOTIDES; ORGANIC ACIDS;

BASE PAIRINGS; DEOXYADENOSINE; DEOXYGUANOSINE; DUPLEX STABILITY; FLUORINE SUBSTITUENTS; FLUORO-SUBSTITUTION; FUNCTIONALIZED; PHOSPHORAMIDITES;

GENES;

7 FLUORO 7 DEAZA 2' DEOXYADENOSINE; 7 FLUORO 7 DEAZA 2' DEOXYGUANOSINE; 7-FLUORO-7-DEAZA-2'-DEOXYADENOSINE; 7-FLUORO-7-DEAZA-2'-DEOXYGUANOSINE; DEOXYADENOSINE DERIVATIVE; DEOXYGUANOSINE; DNA; DRUG DERIVATIVE; OLIGODEOXYRIBONUCLEOTIDE;

ARTICLE; BASE PAIRING; CHEMICAL STRUCTURE; CHEMISTRY; DNA DENATURATION; GENETICS; HALOGENATION; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; SYNTHESIS; TRANSITION TEMPERATURE; X RAY CRYSTALLOGRAPHY;

BASE PAIRING; BASE SEQUENCE; CRYSTALLOGRAPHY, X-RAY; DEOXYADENOSINES; DEOXYGUANOSINE; DNA; HALOGENATION; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; NUCLEIC ACID DENATURATION; OLIGODEOXYRIBONUCLEOTIDES; TRANSITION TEMPERATURE;

EID: 52149122334     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b806145a     Document Type: Article

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