3-Bromopyrazolo[3,4-d]pyrimidine 2′-deoxy-2′-fluoro-β-D-arabinonucleosides: Modified DNA constituents with an unusually rigid sugar N-conformation

Journal of Organic Chemistry

Volumn 68, Issue 14, 2003, Pages 5519-5524

  He, Junlin ^a   Mikhailopulo, Igor ^a,b   Seela, Frank ^a  

^a UNIVERSITY OF OSNABRÜCK   (Germany)

^b INSTITUTE OF BIOORGANIC CHEMISTRY   (Belarus)

Author keywords

[No Author keywords available]

Indexed keywords

DERIVATIVES; DNA; SINGLE CRYSTALS; SOLUTIONS; X RAY ANALYSIS;

NUCLEOSIDES;

AROMATIC HYDROCARBONS;

3 BROMO 1 (2 DEOXY 2 FLUORO BETA DEXTRO ARABINOFURANOSYL) 1H PYRAZOLO[3,4 D]PYRIMIDIN 4,6 DIAMINE; 3 BROMO 4 ISOPROPOXY 1H PYRAZOLO[3,4 D]PYRIMIDIN 6 AMINE; 3 BROMOPYRAZOLO[3,4 D]PYRIMIDINE 2' DEOXY 2' FLUORO BETA DEXTRO ARABINONUCLEOSIDE; 6 AMINO 3 BROMO 1 (2 DEOXY 2 FLUORO BETA DEXTRO ARABINOFURANOSYL) 1H PYRAZOLO[3,4 D]PYRIMIDIN 4 ONE; BROMINE DERIVATIVE; DEOXYGUANOSINE DERIVATIVE; NUCLEIC ACID BASE; NUCLEOSIDE; PURINE 2' DEOXY 2' FLUORO BETA DEXTRO ARABINONUCLEOSIDE; PURINE 2,6 DIAMINE DERIVATIVE; PURINE DERIVATIVE; PYRAZOLO[3,4 D]PYRIMIDINE 2' DEOXY 2' FLUORO BETA DEXTRO ARABINONUCLEOSIDE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATION; CRYSTAL; DNA CONFORMATION; GLYCOSYLATION; ISOMER; SOLID STATE; X RAY CRYSTALLOGRAPHY;

ARABINONUCLEOSIDES; CRYSTALLOGRAPHY, X-RAY; MOLECULAR CONFORMATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PYRIMIDINE NUCLEOSIDES; SOLUTIONS;

EID: 0037999867     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo030051p     Document Type: Article

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