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Volumn 201-202, Issue C, 2008, Pages 111-120

Immunosuppression of experimental autoimmune myasthenia gravis by mycophenolate mofetil

Author keywords

Acetylcholine receptor; Immunosuppression; Myasthenia gravis; Mycophenolate mofetil; Neuromuscular junction

Indexed keywords

CHOLINERGIC RECEPTOR; CHOLINERGIC RECEPTOR ANTIBODY; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER;

EID: 51849128170     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2008.05.029     Document Type: Article
Times cited : (17)

References (53)
  • 1
    • 0034045586 scopus 로고    scopus 로고
    • Mycophenolate mofetil and its mechanisms of action
    • Allison A.C., and Eugui E.M. Mycophenolate mofetil and its mechanisms of action. Immunopharmacology 47 (2000) 85-118
    • (2000) Immunopharmacology , vol.47 , pp. 85-118
    • Allison, A.C.1    Eugui, E.M.2
  • 3
    • 0034960370 scopus 로고    scopus 로고
    • Mycophenolate mofetil: a new immunosuppressive approach. Successful treatment in a case of myasthenia gravis associated with incomplete lupus erythematosus syndrome and hepatitis C virus infection
    • Caponnetto C., Rossi E., and Primavera A. Mycophenolate mofetil: a new immunosuppressive approach. Successful treatment in a case of myasthenia gravis associated with incomplete lupus erythematosus syndrome and hepatitis C virus infection. Eur. Neurol. 46 (2001) 53-54
    • (2001) Eur. Neurol. , vol.46 , pp. 53-54
    • Caponnetto, C.1    Rossi, E.2    Primavera, A.3
  • 4
    • 0035830428 scopus 로고    scopus 로고
    • Mycophenolate mofetil: a safe and promising immunosuppressant in neuromuscular diseases
    • Chaudhry V., Cornblath D.R., Griffin J.W., O'Brien R., and Drachman D.B. Mycophenolate mofetil: a safe and promising immunosuppressant in neuromuscular diseases. Neurology 56 (2001) 94-96
    • (2001) Neurology , vol.56 , pp. 94-96
    • Chaudhry, V.1    Cornblath, D.R.2    Griffin, J.W.3    O'Brien, R.4    Drachman, D.B.5
  • 5
    • 16244406556 scopus 로고    scopus 로고
    • Mycophenolate mofetil and myasthenia gravis
    • Ciafaloni E. Mycophenolate mofetil and myasthenia gravis. Lupus 14 Suppl 1 (2005) s46-49
    • (2005) Lupus , vol.14 , Issue.SUPPL. 1
    • Ciafaloni, E.1
  • 6
    • 0035830461 scopus 로고    scopus 로고
    • Mycophenolate mofetil for myasthenia gravis: an open-label pilot study
    • Ciafaloni E., Massey J.M., Tucker-Lipscomb B., and Sanders D.B. Mycophenolate mofetil for myasthenia gravis: an open-label pilot study. Neurology 56 (2001) 97-99
    • (2001) Neurology , vol.56 , pp. 97-99
    • Ciafaloni, E.1    Massey, J.M.2    Tucker-Lipscomb, B.3    Sanders, D.B.4
  • 7
    • 0033567353 scopus 로고    scopus 로고
    • Mycophenolic acid increases apoptosis, lysosomes and lipid droplets in human lymphoid and monocytic cell lines
    • Cohn R.G., Mirkovich A., Dunlap B., Burton P., Chiu S.H., Eugui E., and Caulfield J.P. Mycophenolic acid increases apoptosis, lysosomes and lipid droplets in human lymphoid and monocytic cell lines. Transplantation 68 (1999) 411-418
    • (1999) Transplantation , vol.68 , pp. 411-418
    • Cohn, R.G.1    Mirkovich, A.2    Dunlap, B.3    Burton, P.4    Chiu, S.H.5    Eugui, E.6    Caulfield, J.P.7
  • 8
    • 0037110423 scopus 로고    scopus 로고
    • The role of antibodies in myasthenia gravis
    • De Baets M., and Stassen M.H. The role of antibodies in myasthenia gravis. Ann. N.Y. Acad. Sci. 202 (2002) 5-11
    • (2002) Ann. N.Y. Acad. Sci. , vol.202 , pp. 5-11
    • De Baets, M.1    Stassen, M.H.2
  • 9
    • 0141615841 scopus 로고    scopus 로고
    • Immunoregulation in experimental autoimmune myasthenia gravis-about T cells, antibodies, and endplates
    • De Baets M., Stassen M., Losen M., Zhang X., and Machiels B. Immunoregulation in experimental autoimmune myasthenia gravis-about T cells, antibodies, and endplates. Ann. N.Y. Acad. Sci. 998 (2003) 308-317
    • (2003) Ann. N.Y. Acad. Sci. , vol.998 , pp. 308-317
    • De Baets, M.1    Stassen, M.2    Losen, M.3    Zhang, X.4    Machiels, B.5
  • 11
    • 0028779203 scopus 로고
    • Myasthenia gravis
    • Drachman D.B. Myasthenia gravis. N. Engl. J. Med. 330 (1994) 1797-1810
    • (1994) N. Engl. J. Med. , vol.330 , pp. 1797-1810
    • Drachman, D.B.1
  • 12
    • 0032838201 scopus 로고    scopus 로고
    • Antiinflammatory properties of mycophenolate mofetil in murine endotoxemia: inhibition of TNF-alpha and upregulation of IL-10 release
    • Durez P., Appelboom T., Pira C., Stordeur P., Vray B., and Goldman M. Antiinflammatory properties of mycophenolate mofetil in murine endotoxemia: inhibition of TNF-alpha and upregulation of IL-10 release. Int. J. Immunopharmacol. 21 (1999) 581-587
    • (1999) Int. J. Immunopharmacol. , vol.21 , pp. 581-587
    • Durez, P.1    Appelboom, T.2    Pira, C.3    Stordeur, P.4    Vray, B.5    Goldman, M.6
  • 13
    • 0030796024 scopus 로고    scopus 로고
    • Treatment of pemphigus vulgaris with mycophenolate mofetil
    • Enk A.H., and Knop J. Treatment of pemphigus vulgaris with mycophenolate mofetil. Lancet 350 (1997) 494
    • (1997) Lancet , vol.350 , pp. 494
    • Enk, A.H.1    Knop, J.2
  • 14
    • 0025760659 scopus 로고
    • Lymphocyte-selective antiproliferative and immunosuppressive activity of mycophenolic acid and its morpholinoethyl ester (RS-61443) in rodents
    • Eugui E.M., Mirkovich A., and Allison A.C. Lymphocyte-selective antiproliferative and immunosuppressive activity of mycophenolic acid and its morpholinoethyl ester (RS-61443) in rodents. Transplant. Proc. 23 (1991) 15-18
    • (1991) Transplant. Proc. , vol.23 , pp. 15-18
    • Eugui, E.M.1    Mirkovich, A.2    Allison, A.C.3
  • 15
    • 0029006409 scopus 로고
    • Placebo-controlled study of mycophenolate mofetil combined with cyclosporin and corticosteroids for prevention of acute rejection
    • European Mycophenolate Mofetil Cooperative Study Group. Placebo-controlled study of mycophenolate mofetil combined with cyclosporin and corticosteroids for prevention of acute rejection. Lancet 345 (1995) 1321-1325
    • (1995) Lancet , vol.345 , pp. 1321-1325
    • European Mycophenolate Mofetil Cooperative Study Group1
  • 18
    • 35748963843 scopus 로고    scopus 로고
    • Mycophenolate mofetil and atherosclerosis: results of animal and human studies
    • Gibson W.T., and Hayden M.R. Mycophenolate mofetil and atherosclerosis: results of animal and human studies. Ann. N. Y. Acad. Sci. 1110 (2007) 209-221
    • (2007) Ann. N. Y. Acad. Sci. , vol.1110 , pp. 209-221
    • Gibson, W.T.1    Hayden, M.R.2
  • 20
    • 0027156705 scopus 로고
    • Therapy of rheumatoid arthritis with mycophenolate mofetil
    • Goldblum R. Therapy of rheumatoid arthritis with mycophenolate mofetil. Clin. Exp. Rheumatol. 11 Suppl 8 (1993) S117-119
    • (1993) Clin. Exp. Rheumatol. , vol.11 , Issue.SUPPL. 8
    • Goldblum, R.1
  • 21
    • 0034641233 scopus 로고    scopus 로고
    • Practice parameter: thymectomy for autoimmune myasthenia gravis (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology
    • Gronseth G.S., and Barohn R.J. Practice parameter: thymectomy for autoimmune myasthenia gravis (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 55 (2000) 7-15
    • (2000) Neurology , vol.55 , pp. 7-15
    • Gronseth, G.S.1    Barohn, R.J.2
  • 22
    • 0032797568 scopus 로고    scopus 로고
    • Glutathione-dependent metabolism of cis-3-(9H-purin-6-ylthio)acrylic acid to yield the chemotherapeutic drug 6-mercaptopurine: evidence for two distinct mechanisms in rats
    • Gunnarsdottir S., and Elfarra A.A. Glutathione-dependent metabolism of cis-3-(9H-purin-6-ylthio)acrylic acid to yield the chemotherapeutic drug 6-mercaptopurine: evidence for two distinct mechanisms in rats. J. Pharmacol. Exp. Ther. 290 (1999) 950-957
    • (1999) J. Pharmacol. Exp. Ther. , vol.290 , pp. 950-957
    • Gunnarsdottir, S.1    Elfarra, A.A.2
  • 23
    • 0023726069 scopus 로고
    • Comparison of cyclosporin A and G with and without azathioprine regarding immunosuppressive efficacy, toxicity, and pharmacokinetics in Lewis rats
    • Hagberg R.C., Hoyt E.G., Billingham M.E., Sibley R.K., Starnes V.A., and Baldwin J.C. Comparison of cyclosporin A and G with and without azathioprine regarding immunosuppressive efficacy, toxicity, and pharmacokinetics in Lewis rats. J. Heart. Transplant. 7 (1988) 359-369
    • (1988) J. Heart. Transplant. , vol.7 , pp. 359-369
    • Hagberg, R.C.1    Hoyt, E.G.2    Billingham, M.E.3    Sibley, R.K.4    Starnes, V.A.5    Baldwin, J.C.6
  • 24
    • 34347403042 scopus 로고    scopus 로고
    • Trials assess myasthenia gravis therapies
    • Hampton T. Trials assess myasthenia gravis therapies. Jama 298 (2007) 29-30
    • (2007) Jama , vol.298 , pp. 29-30
    • Hampton, T.1
  • 25
    • 0031752263 scopus 로고    scopus 로고
    • Successful treatment of a patient with severe refractory myasthenia gravis using mycophenolate mofetil
    • Hauser R.A., Malek A.R., and Rosen R. Successful treatment of a patient with severe refractory myasthenia gravis using mycophenolate mofetil. Neurology 51 (1998) 912-913
    • (1998) Neurology , vol.51 , pp. 912-913
    • Hauser, R.A.1    Malek, A.R.2    Rosen, R.3
  • 26
    • 0035105784 scopus 로고    scopus 로고
    • Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies
    • Hoch W., McConville J., Helms S., Newsom-Davis J., Melms A., and Vincent A. Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies. Nat. Med. 7 (2001) 365-368
    • (2001) Nat. Med. , vol.7 , pp. 365-368
    • Hoch, W.1    McConville, J.2    Helms, S.3    Newsom-Davis, J.4    Melms, A.5    Vincent, A.6
  • 27
    • 0031014572 scopus 로고    scopus 로고
    • Age- and sex-related resistance to chronic experimental autoimmune myasthenia gravis (EAMG) in Brown Norway rats
    • Hoedemaekers A., Graus Y., van Breda Vriesman P., and de Baets M. Age- and sex-related resistance to chronic experimental autoimmune myasthenia gravis (EAMG) in Brown Norway rats. Clin. Exp. Immunol. 107 (1997) 189-197
    • (1997) Clin. Exp. Immunol. , vol.107 , pp. 189-197
    • Hoedemaekers, A.1    Graus, Y.2    van Breda Vriesman, P.3    de Baets, M.4
  • 29
    • 0033506431 scopus 로고    scopus 로고
    • Mycophenolate mofetil. A useful immunosuppressive in inflammatory eye disease
    • Larkin G., and Lightman S. Mycophenolate mofetil. A useful immunosuppressive in inflammatory eye disease. Ophthalmology 106 (1999) 370-374
    • (1999) Ophthalmology , vol.106 , pp. 370-374
    • Larkin, G.1    Lightman, S.2
  • 30
    • 33747157912 scopus 로고    scopus 로고
    • Plasma exchange in neuroimmunological disorders: part 2. Treatment of neuromuscular disorders
    • Lehmann H.C., Hartung H.P., Hetzel G.R., Stuve O., and Kieseier B.C. Plasma exchange in neuroimmunological disorders: part 2. Treatment of neuromuscular disorders. Arch. Neurol. 63 (2006) 1066-1071
    • (2006) Arch. Neurol. , vol.63 , pp. 1066-1071
    • Lehmann, H.C.1    Hartung, H.P.2    Hetzel, G.R.3    Stuve, O.4    Kieseier, B.C.5
  • 31
    • 0016796265 scopus 로고
    • Experimental autoimmune myasthenia: a model of myasthenia gravis in rats and guinea pigs
    • Lennon V.A., Lindstrom J.M., and Seybold M.E. Experimental autoimmune myasthenia: a model of myasthenia gravis in rats and guinea pigs. J. Exp. Med. 141 (1975) 1365-1375
    • (1975) J. Exp. Med. , vol.141 , pp. 1365-1375
    • Lennon, V.A.1    Lindstrom, J.M.2    Seybold, M.E.3
  • 32
    • 33845515282 scopus 로고    scopus 로고
    • Mycophenolate mofetil substitution for cyclosporine-dependent myasthenia gravis and nephrotoxicity
    • Lim A.K., Donnan G., Chambers B., and Ierino F.L. Mycophenolate mofetil substitution for cyclosporine-dependent myasthenia gravis and nephrotoxicity. Intern. Med. J. 37 (2007) 55-59
    • (2007) Intern. Med. J. , vol.37 , pp. 55-59
    • Lim, A.K.1    Donnan, G.2    Chambers, B.3    Ierino, F.L.4
  • 33
    • 0017171683 scopus 로고
    • Antibody to acetylcholine receptor in myasthenia gravis. Prevalence, clinical correlates, and diagnostic value
    • Lindstrom J.M., Seybold M.E., Lennon V.A., Whittingham S., and Duane D.D. Antibody to acetylcholine receptor in myasthenia gravis. Prevalence, clinical correlates, and diagnostic value. Neurology 26 (1976) 1054-1059
    • (1976) Neurology , vol.26 , pp. 1054-1059
    • Lindstrom, J.M.1    Seybold, M.E.2    Lennon, V.A.3    Whittingham, S.4    Duane, D.D.5
  • 36
    • 33947543878 scopus 로고    scopus 로고
    • Overexpression of rapsyn in rat muscle increases acetylcholine receptor levels in chronic experimental autoimmune myasthenia gravis
    • Martinez-Martinez P., Losen M., Duimel H., Frederik P., Spaans F., Molenaar P., Vincent A., and De Baets M.H. Overexpression of rapsyn in rat muscle increases acetylcholine receptor levels in chronic experimental autoimmune myasthenia gravis. Am. J. Pathol. 170 (2007) 644-657
    • (2007) Am. J. Pathol. , vol.170 , pp. 644-657
    • Martinez-Martinez, P.1    Losen, M.2    Duimel, H.3    Frederik, P.4    Spaans, F.5    Molenaar, P.6    Vincent, A.7    De Baets, M.H.8
  • 38
    • 0141615801 scopus 로고    scopus 로고
    • Mycophenolate mofetil for myasthenia gravis: a double-blind, placebo-controlled pilot study
    • Meriggioli M.N., Rowin J., Richman J.G., and Leurgans S. Mycophenolate mofetil for myasthenia gravis: a double-blind, placebo-controlled pilot study. Ann. N. Y. Acad. Sci. 998 (2003) 494-499
    • (2003) Ann. N. Y. Acad. Sci. , vol.998 , pp. 494-499
    • Meriggioli, M.N.1    Rowin, J.2    Richman, J.G.3    Leurgans, S.4
  • 39
    • 0035310730 scopus 로고    scopus 로고
    • Mycophenolate (CellCept) treatment of myasthenia gravis, chronic inflammatory polyneuropathy and inclusion body myositis
    • Mowzoon N., Sussman A., and Bradley W.G. Mycophenolate (CellCept) treatment of myasthenia gravis, chronic inflammatory polyneuropathy and inclusion body myositis. J. Neurol. Sci. 185 (2001) 119-122
    • (2001) J. Neurol. Sci. , vol.185 , pp. 119-122
    • Mowzoon, N.1    Sussman, A.2    Bradley, W.G.3
  • 40
    • 0033003888 scopus 로고    scopus 로고
    • Randomised trial of mycophenolate mofetil versus azathioprine for treatment of chronic active Crohn's disease
    • Neurath M.F., Wanitschke R., Peters M., Krummenauer F., Meyer zum Buschenfelde K.H., and Schlaak J.F. Randomised trial of mycophenolate mofetil versus azathioprine for treatment of chronic active Crohn's disease. Gut 44 (1999) 625-628
    • (1999) Gut , vol.44 , pp. 625-628
    • Neurath, M.F.1    Wanitschke, R.2    Peters, M.3    Krummenauer, F.4    Meyer zum Buschenfelde, K.H.5    Schlaak, J.F.6
  • 41
    • 0344549857 scopus 로고    scopus 로고
    • Mycophenolate mofetil for maintenance therapy of Wegener's granulomatosis and microscopic polyangiitis: a pilot study in 11 patients with renal involvement
    • Nowack R., Gobel U., Klooker P., Hergesell O., Andrassy K., and van der Woude F.J. Mycophenolate mofetil for maintenance therapy of Wegener's granulomatosis and microscopic polyangiitis: a pilot study in 11 patients with renal involvement. J. Am. Soc. Nephrol. 10 (1999) 1965-1971
    • (1999) J. Am. Soc. Nephrol. , vol.10 , pp. 1965-1971
    • Nowack, R.1    Gobel, U.2    Klooker, P.3    Hergesell, O.4    Andrassy, K.5    van der Woude, F.J.6
  • 42
    • 0031747483 scopus 로고    scopus 로고
    • A randomized double-blind trial of prednisolone alone or with azathioprine in myasthenia gravis. Myasthenia Gravis Study Group
    • Palace J., Newsom-Davis J., and Lecky B. A randomized double-blind trial of prednisolone alone or with azathioprine in myasthenia gravis. Myasthenia Gravis Study Group. Neurology 50 (1998) 1778-1783
    • (1998) Neurology , vol.50 , pp. 1778-1783
    • Palace, J.1    Newsom-Davis, J.2    Lecky, B.3
  • 43
    • 33746866362 scopus 로고    scopus 로고
    • Azathioprine in dermatology: the past, the present, and the future
    • Patel A.A., Swerlick R.A., and McCall C.O. Azathioprine in dermatology: the past, the present, and the future. J. Am. Acad. Dermatol. 55 (2006) 369-389
    • (2006) J. Am. Acad. Dermatol. , vol.55 , pp. 369-389
    • Patel, A.A.1    Swerlick, R.A.2    McCall, C.O.3
  • 44
    • 33846365961 scopus 로고    scopus 로고
    • Mycophenolate mofetil - as an adjunctive immunosuppressive therapy in refractory myasthenia gravis: the Singapore experience
    • Prakash K.M., Ratnagopal P., Puvanendran K., and Lo Y.L. Mycophenolate mofetil - as an adjunctive immunosuppressive therapy in refractory myasthenia gravis: the Singapore experience. J. Clin. Neurosci. 14 (2007) 278-281
    • (2007) J. Clin. Neurosci. , vol.14 , pp. 278-281
    • Prakash, K.M.1    Ratnagopal, P.2    Puvanendran, K.3    Lo, Y.L.4
  • 45
    • 0347994922 scopus 로고    scopus 로고
    • Treatment of autoimmune myasthenia gravis
    • Richman D.P., and Agius M.A. Treatment of autoimmune myasthenia gravis. Neurology 61 (2003) 1652-1661
    • (2003) Neurology , vol.61 , pp. 1652-1661
    • Richman, D.P.1    Agius, M.A.2
  • 47
    • 33748030791 scopus 로고    scopus 로고
    • Mycophenolate mofetil and tacrolimus: new therapeutic options in neuroimmunological diseases
    • Schneider-Gold C., Hartung H.P., and Gold R. Mycophenolate mofetil and tacrolimus: new therapeutic options in neuroimmunological diseases. Muscle. Nerve. 34 (2006) 284-291
    • (2006) Muscle. Nerve. , vol.34 , pp. 284-291
    • Schneider-Gold, C.1    Hartung, H.P.2    Gold, R.3
  • 48
    • 0034860169 scopus 로고    scopus 로고
    • Mycophenolate mofetil in the therapy of severe myasthenia gravis
    • Schneider C., Gold R., Reiners K., and Toyka K.V. Mycophenolate mofetil in the therapy of severe myasthenia gravis. Eur. Neurol. 46 (2001) 79-82
    • (2001) Eur. Neurol. , vol.46 , pp. 79-82
    • Schneider, C.1    Gold, R.2    Reiners, K.3    Toyka, K.V.4
  • 49
    • 0016909457 scopus 로고
    • Experimental autoimmune myasthenia: clinical, neurophysiologic, and pharmacologic aspects
    • Seybold M.E., Lambert E.H., Lennon V.A., and Lindstrom J.M. Experimental autoimmune myasthenia: clinical, neurophysiologic, and pharmacologic aspects. Ann. N. Y. Acad. Sci. 274 (1976) 275-282
    • (1976) Ann. N. Y. Acad. Sci. , vol.274 , pp. 275-282
    • Seybold, M.E.1    Lambert, E.H.2    Lennon, V.A.3    Lindstrom, J.M.4
  • 50
    • 18744405455 scopus 로고    scopus 로고
    • Myasthenia gravis: emerging new therapy options
    • Sieb J.P. Myasthenia gravis: emerging new therapy options. Curr. Opin. Pharmacol. 5 (2005) 303-307
    • (2005) Curr. Opin. Pharmacol. , vol.5 , pp. 303-307
    • Sieb, J.P.1
  • 51
    • 49049115186 scopus 로고    scopus 로고
    • A trial of mycophenolate mofetil with prednisone as initial immunotherapy in myasthenia gravis
    • 10.1212/01.wnl.0000312374.95186.cc
    • The Muscle Study Group. A trial of mycophenolate mofetil with prednisone as initial immunotherapy in myasthenia gravis. Neurology (2008) 10.1212/01.wnl.0000312374.95186.cc
    • (2008) Neurology
    • The Muscle Study Group1
  • 52
    • 0034887124 scopus 로고    scopus 로고
    • Mycophenolate mofetil treatment accelerates recovery from experimental allergic encephalomyelitis
    • Tran G.T., Carter N., and Hodgkinson S.J. Mycophenolate mofetil treatment accelerates recovery from experimental allergic encephalomyelitis. Int. Immunopharmacol. 1 (2001) 1709-1723
    • (2001) Int. Immunopharmacol. , vol.1 , pp. 1709-1723
    • Tran, G.T.1    Carter, N.2    Hodgkinson, S.J.3
  • 53
    • 16244398658 scopus 로고    scopus 로고
    • Mycophenolate mofetil in animal models of autoimmune disease
    • Zandman-Goddard G., and Shoenfeld Y. Mycophenolate mofetil in animal models of autoimmune disease. Lupus 14 Suppl 1 (2005) s12-16
    • (2005) Lupus , vol.14 , Issue.SUPPL. 1
    • Zandman-Goddard, G.1    Shoenfeld, Y.2


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