메뉴 건너뛰기




Volumn 74, Issue 7, 2008, Pages 937-945

Effects of uremia and inflammation on growth hormone resistance in patients with chronic kidney diseases

Author keywords

Amino acid; Chronic renal failure; Growth hormone; Inflammation; K+; Malnutrition

Indexed keywords

BRANCHED CHAIN AMINO ACID; C REACTIVE PROTEIN; HORMONE RECEPTOR; HUMAN GROWTH HORMONE; INTERLEUKIN 6; POTASSIUM;

EID: 51849106367     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2008.345     Document Type: Article
Times cited : (30)

References (49)
  • 1
    • 33745664778 scopus 로고    scopus 로고
    • Proteolytic mechanisms, not malnutrition, cause loss of muscle mass in kidney failure
    • Mitch WE. Proteolytic mechanisms, not malnutrition, cause loss of muscle mass in kidney failure. J Ren Nutr 2006; 16: 208-211.
    • (2006) J Ren Nutr , vol.16 , pp. 208-211
    • Mitch, W.E.1
  • 2
    • 0031737649 scopus 로고    scopus 로고
    • Malnutrition, cardiac disease, and mortality: An integrated point of view
    • Bergstrom J, Lindholm B. Malnutrition, cardiac disease, and mortality: an integrated point of view. Am J Kidney Dis 1998; 32: 834-841.
    • (1998) Am J Kidney Dis , vol.32 , pp. 834-841
    • Bergstrom, J.1    Lindholm, B.2
  • 3
    • 0035720091 scopus 로고    scopus 로고
    • A malnutrition- inflammation score is correlated with morbidity and mortality in maintenance hemodialysis patients
    • Kalantar-Zadeh K, Kopple JD, Block G et al. A malnutrition- inflammation score is correlated with morbidity and mortality in maintenance hemodialysis patients. Am J Kidney Dis 2001; 38: 1251-1263.
    • (2001) Am J Kidney Dis , vol.38 , pp. 1251-1263
    • Kalantar-Zadeh, K.1    Kopple, J.D.2    Block, G.3
  • 4
    • 0034076113 scopus 로고    scopus 로고
    • Relationship between nutritional status and the glomerular filtration rate: Results from the MDRD study
    • Kopple JD, Greene T, Chumlea WC et al. Relationship between nutritional status and the glomerular filtration rate: Results from the MDRD study. Kidney Int 2000; 57: 1688-1703.
    • (2000) Kidney Int , vol.57 , pp. 1688-1703
    • Kopple, J.D.1    Greene, T.2    Chumlea, W.C.3
  • 5
    • 0029616430 scopus 로고
    • Uremic acidosis and protein metabolism
    • Mitch WE. Uremic acidosis and protein metabolism. Curr Opin Nephrol Hypertens 1995; 4: 488-492.
    • (1995) Curr Opin Nephrol Hypertens , vol.4 , pp. 488-492
    • Mitch, W.E.1
  • 6
    • 0026654408 scopus 로고
    • Growth hormone stimulates skeletal muscle protein synthesis and antagonizes insulin's antiproteolytic action in humans
    • Fryburg DA, Louard RJ, Gerow KE. Growth hormone stimulates skeletal muscle protein synthesis and antagonizes insulin's antiproteolytic action in humans. Diabetes 1992; 41: 424-429.
    • (1992) Diabetes , vol.41 , pp. 424-429
    • Fryburg, D.A.1    Louard, R.J.2    Gerow, K.E.3
  • 8
    • 0041429430 scopus 로고    scopus 로고
    • Chronic renal disease: A growing problem
    • Kaskel F. Chronic renal disease: a growing problem. Kidney Int 2003; 64: 1141-1151.
    • (2003) Kidney Int , vol.64 , pp. 1141-1151
    • Kaskel, F.1
  • 9
    • 0035315915 scopus 로고    scopus 로고
    • Growth factors in the treatment of wasting in kidney failure
    • Chen Y, Fervenza FC, Rabkin R. Growth factors in the treatment of wasting in kidney failure. J Ren Nutr 2001; 11: 62-66.
    • (2001) J Ren Nutr , vol.11 , pp. 62-66
    • Chen, Y.1    Fervenza, F.C.2    Rabkin, R.3
  • 10
    • 0032957675 scopus 로고    scopus 로고
    • Elevated myocardial cytosolic calcium impairs insulin-like growth factor-1-stimulated protein synthesis in chronic renal failure
    • Qing Peiyuan D, Ding HU, Vadgama J et al. Elevated myocardial cytosolic calcium impairs insulin-like growth factor-1-stimulated protein synthesis in chronic renal failure. J Am Soc Nephrol 1999; 10: 84-92.
    • (1999) J Am Soc Nephrol , vol.10 , pp. 84-92
    • Qing Peiyuan, D.1    Ding, H.U.2    Vadgama, J.3
  • 11
    • 8044234956 scopus 로고    scopus 로고
    • Decreased hepatic insulin-like growth factor (IGF)-I and increased IGF binding protein-1 and -2 gene expression in experimental uremia
    • Powell DR, Zhao D, Durham SK et al. Decreased hepatic insulin-like growth factor (IGF)-I and increased IGF binding protein-1 and -2 gene expression in experimental uremia. Endocrinology 1997; 138: 938-946.
    • (1997) Endocrinology , vol.138 , pp. 938-946
    • Powell, D.R.1    Zhao, D.2    Durham, S.K.3
  • 12
    • 0025900723 scopus 로고
    • Growth hormone resistance and inhibition of somatomedin activity by excess of insulin-like growth factor binding protein in uremia
    • Blum WF, Ranke MB, Kietzmann K et al. Growth hormone resistance and inhibition of somatomedin activity by excess of insulin-like growth factor binding protein in uremia. Pediatr Nephrol 1991; 5: 539-544.
    • (1991) Pediatr Nephrol , vol.5 , pp. 539-544
    • Blum, W.F.1    Ranke, M.B.2    Kietzmann, K.3
  • 13
    • 14644399472 scopus 로고    scopus 로고
    • Chronic uremia attenuates growth hormone-induced signal transduction in skeletal muscle
    • Sun DF, Zheng Z, Tummala P et al. Chronic uremia attenuates growth hormone-induced signal transduction in skeletal muscle. J Am Soc Nephrol 2004; 15: 2630-2646.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2630-2646
    • Sun, D.F.1    Zheng, Z.2    Tummala, P.3
  • 14
    • 0028899137 scopus 로고
    • Impaired metabolic response to recombinant insulin-like growth factor-1 in dialysis patients
    • Fouque D, Peng SC, Kopple JD. Impaired metabolic response to recombinant insulin-like growth factor-1 in dialysis patients. Kidney Int 1995; 47: 876-883.
    • (1995) Kidney Int , vol.47 , pp. 876-883
    • Fouque, D.1    Peng, S.C.2    Kopple, J.D.3
  • 15
    • 0033946859 scopus 로고    scopus 로고
    • Recombinant human insulin-like growth factor-1 induces an anabolic response in malnourished CAPD patients
    • Fouque D, Peng SC, Shamir E et al. Recombinant human insulin-like growth factor-1 induces an anabolic response in malnourished CAPD patients. Kidney Int 2000; 57: 646-654.
    • (2000) Kidney Int , vol.57 , pp. 646-654
    • Fouque, D.1    Peng, S.C.2    Shamir, E.3
  • 16
    • 0029811744 scopus 로고    scopus 로고
    • Effects of recombinant human growth hormone on plasma and dialysate amino acid profiles in CAPD patients
    • Ikizler TA, Wingard RL, Flakoll PJ et al. Effects of recombinant human growth hormone on plasma and dialysate amino acid profiles in CAPD patients. Kidney Int 1996; 50: 229-234.
    • (1996) Kidney Int , vol.50 , pp. 229-234
    • Ikizler, T.A.1    Wingard, R.L.2    Flakoll, P.J.3
  • 17
    • 0031036914 scopus 로고    scopus 로고
    • Effects of recombinant human growth hormone on muscle protein turnover in malnourished hemodialysis patients
    • Garibotto G, Barreca A, Russo R et al. Effects of recombinant human growth hormone on muscle protein turnover in malnourished hemodialysis patients. J Clin Invest 1997; 99: 97-105.
    • (1997) J Clin Invest , vol.99 , pp. 97-105
    • Garibotto, G.1    Barreca, A.2    Russo, R.3
  • 18
    • 33644692485 scopus 로고    scopus 로고
    • Pupim LB, Flakoll PJ, Yu C et al. Recombinant human growth hormone improves muscle amino acid uptake and whole-body protein metabolism in chronic hemodialysis patients. Am J Clin Nutr 20055; 82: 1235-1243.
    • Pupim LB, Flakoll PJ, Yu C et al. Recombinant human growth hormone improves muscle amino acid uptake and whole-body protein metabolism in chronic hemodialysis patients. Am J Clin Nutr 20055; 82: 1235-1243.
  • 19
    • 0034791529 scopus 로고    scopus 로고
    • Differential effects of growth hormone therapy in malnourished hemodialysis patients
    • Kotzmann H, Yilmaz N, Lercher P et al. Differential effects of growth hormone therapy in malnourished hemodialysis patients. Kidney Int 2001; 60: 1578-1585.
    • (2001) Kidney Int , vol.60 , pp. 1578-1585
    • Kotzmann, H.1    Yilmaz, N.2    Lercher, P.3
  • 20
    • 18944392703 scopus 로고    scopus 로고
    • Growth hormone induces anabolism in malnourished maintenance haemodialysis patients
    • Kopple JD, Brunori G, Leiserowitz M et al. Growth hormone induces anabolism in malnourished maintenance haemodialysis patients. Nephrol Dial Transplant 2005; 20: 952-958.
    • (2005) Nephrol Dial Transplant , vol.20 , pp. 952-958
    • Kopple, J.D.1    Brunori, G.2    Leiserowitz, M.3
  • 21
    • 34447293565 scopus 로고    scopus 로고
    • Growth hormone treatment during hemodialysis in a randomized trial improves nutrition, quality of life, and cardiovascular risk
    • Feldt-Rasmussen B, Lange M, Sulowicz W et al. Growth hormone treatment during hemodialysis in a randomized trial improves nutrition, quality of life, and cardiovascular risk. J Am Soc Nephrol 2007; 18: 2161-2171.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 2161-2171
    • Feldt-Rasmussen, B.1    Lange, M.2    Sulowicz, W.3
  • 22
    • 0025973547 scopus 로고
    • Growth hormone treatment in growth hormone-deficient adults. I. Effects on muscle mass and strength
    • Cuneo RC, Salomon F, Wiles CM et al. Growth hormone treatment in growth hormone-deficient adults. I. Effects on muscle mass and strength. J Appl Physiol 1991; 70: 688-694.
    • (1991) J Appl Physiol , vol.70 , pp. 688-694
    • Cuneo, R.C.1    Salomon, F.2    Wiles, C.M.3
  • 23
    • 33947726760 scopus 로고    scopus 로고
    • The inhibitory effects of interleukin-1 on growth hormone action during catabolic illness
    • Cooney RN, Shumate M. The inhibitory effects of interleukin-1 on growth hormone action during catabolic illness. Vitam Horm 2006; 74: 317-340.
    • (2006) Vitam Horm , vol.74 , pp. 317-340
    • Cooney, R.N.1    Shumate, M.2
  • 24
    • 0031047919 scopus 로고    scopus 로고
    • Effect of chronic metabolic acidosis on the growth hormone/IGF-1 endocrine axis: New cause of growth hormone insensitivity in humans
    • Brungger M, Hulter HN, Krapf R. Effect of chronic metabolic acidosis on the growth hormone/IGF-1 endocrine axis: new cause of growth hormone insensitivity in humans. Kidney Int 1997; 51: 216-221.
    • (1997) Kidney Int , vol.51 , pp. 216-221
    • Brungger, M.1    Hulter, H.N.2    Krapf, R.3
  • 25
    • 33846492998 scopus 로고    scopus 로고
    • Visualizing and manipulating growth hormone (GH) responses in muscle and other GH target tissues
    • Robinson IC, Gevers E. Visualizing and manipulating growth hormone (GH) responses in muscle and other GH target tissues. Horm Res 2006; 66S1: 35-41.
    • (2006) Horm Res , vol.66 S1 , pp. 35-41
    • Robinson, I.C.1    Gevers, E.2
  • 26
    • 34047112782 scopus 로고    scopus 로고
    • Importance of PPAR alpha for the effects of growth hormone on hepatic lipid and lipoprotein metabolism
    • Ljungberg A, Linden D, Ameen C et al. Importance of PPAR alpha for the effects of growth hormone on hepatic lipid and lipoprotein metabolism. Growth Horm IGF Res 2007; 17: 154-164.
    • (2007) Growth Horm IGF Res , vol.17 , pp. 154-164
    • Ljungberg, A.1    Linden, D.2    Ameen, C.3
  • 27
    • 34447578825 scopus 로고    scopus 로고
    • The rapid activation of protein synthesis by growth hormone requires signaling through the mammalian target of rapamycin, mTOR
    • Hayashi AA, Proud CG. The rapid activation of protein synthesis by growth hormone requires signaling through the mammalian target of rapamycin, mTOR. Am J Physiol Endocrinol Metab 2007; 292: E1647-E1655.
    • (2007) Am J Physiol Endocrinol Metab , vol.292
    • Hayashi, A.A.1    Proud, C.G.2
  • 28
    • 0026667542 scopus 로고
    • Basal metabolic rate in adults with growth hormone deficiency and in patients with acromegaly: Relationship with lean body mass, plasma insulin level and leucocyte sodium pump activity
    • Salomon F, Cuneo RC, Hesp R et al. Basal metabolic rate in adults with growth hormone deficiency and in patients with acromegaly: relationship with lean body mass, plasma insulin level and leucocyte sodium pump activity. Clin Sci 1992; 83: 325-330.
    • (1992) Clin Sci , vol.83 , pp. 325-330
    • Salomon, F.1    Cuneo, R.C.2    Hesp, R.3
  • 29
    • 0032977145 scopus 로고    scopus 로고
    • Acute and short-term effects of growth hormone on insulin-like growth factors and their binding proteins: Serum levels and hepatic messenger ribonucleic acid responses in humans
    • Olivecrona H, Hilding A, Ekstrom C et al. Acute and short-term effects of growth hormone on insulin-like growth factors and their binding proteins: serum levels and hepatic messenger ribonucleic acid responses in humans. J Clin Endocrinol Metab 1999; 84: 553-560.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 553-560
    • Olivecrona, H.1    Hilding, A.2    Ekstrom, C.3
  • 30
    • 0027445831 scopus 로고
    • Growth hormone acutely stimulates skeletal muscle but not whole-body protein synthesis in humans
    • Fryburg D, Gelfand G. Growth hormone acutely stimulates skeletal muscle but not whole-body protein synthesis in humans. Metabolism 1993; 42: 1223-1227.
    • (1993) Metabolism , vol.42 , pp. 1223-1227
    • Fryburg, D.1    Gelfand, G.2
  • 31
  • 32
    • 0018563838 scopus 로고
    • Serum electrolyte and acid base composition. The influence of graded degrees of chronic renal failure
    • Widmer B, Gerhardt RE, Harrington JT et al. Serum electrolyte and acid base composition. The influence of graded degrees of chronic renal failure. Arch Intern Med 1979; 139: 1099-1102.
    • (1979) Arch Intern Med , vol.139 , pp. 1099-1102
    • Widmer, B.1    Gerhardt, R.E.2    Harrington, J.T.3
  • 33
    • 0036311146 scopus 로고    scopus 로고
    • Hyperkalemia: An adaptive response in chronic renal insufficiency
    • Gennari FJ, Segal AS. Hyperkalemia: an adaptive response in chronic renal insufficiency. Kidney Int 2002; 62: 1-9.
    • (2002) Kidney Int , vol.62 , pp. 1-9
    • Gennari, F.J.1    Segal, A.S.2
  • 34
    • 0025000703 scopus 로고
    • Albuterol and insulin for treatment of hyperkalemia in hemodialysis patients
    • Allon M, Copckney C. Albuterol and insulin for treatment of hyperkalemia in hemodialysis patients. Kidney Int 1990; 38: 869-872.
    • (1990) Kidney Int , vol.38 , pp. 869-872
    • Allon, M.1    Copckney, C.2
  • 35
    • 0030663542 scopus 로고    scopus 로고
    • Metabolic effects and pharmacokinetics of a growth hormone pulse in healthy adults: Relation to age, sex, and body composition
    • Vahl N, Moller N, Lauritzen T et al. Metabolic effects and pharmacokinetics of a growth hormone pulse in healthy adults: relation to age, sex, and body composition. J Clin Endocrinol Metab 1997; 82: 3612-3618.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 3612-3618
    • Vahl, N.1    Moller, N.2    Lauritzen, T.3
  • 36
    • 0036775478 scopus 로고    scopus 로고
    • Dose dependency of the pharmacokinetics and acute lipolytic actions of growth hormone
    • Hansen TK, Gravholt CH, ØRskov H et al. Dose dependency of the pharmacokinetics and acute lipolytic actions of growth hormone. J Clin Endocrinol Metab 2002; 87: 4691-4698.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 4691-4698
    • Hansen, T.K.1    Gravholt, C.H.2    ØRskov, H.3
  • 37
    • 0023930989 scopus 로고
    • The circulating growth hormone (GH)-binding protein complex: A major constituent of plasma GH in man
    • Baumann G, Amburn K, Shaw MA. The circulating growth hormone (GH)-binding protein complex: a major constituent of plasma GH in man. Endocrinology 1988; 122: 976-984.
    • (1988) Endocrinology , vol.122 , pp. 976-984
    • Baumann, G.1    Amburn, K.2    Shaw, M.A.3
  • 38
    • 33645303213 scopus 로고    scopus 로고
    • Circulating growth hormone binding protein levels and mononuclear cell growth hormone receptor expression in uremia
    • Greenstein J, Guest S, Tan JC et al. Circulating growth hormone binding protein levels and mononuclear cell growth hormone receptor expression in uremia. J Ren Nutr 2006; 16: 141-149.
    • (2006) J Ren Nutr , vol.16 , pp. 141-149
    • Greenstein, J.1    Guest, S.2    Tan, J.C.3
  • 40
    • 34447572787 scopus 로고    scopus 로고
    • Endotoxin attenuates growth hormone induced hepatic insulin-like growth factor-1 expresion by inhibiting Jak2/Stat5 signal transduction and Stat5b DNA binding
    • Chen Y, Sun D, Krishnamurthy VM et al. Endotoxin attenuates growth hormone induced hepatic insulin-like growth factor-1 expresion by inhibiting Jak2/Stat5 signal transduction and Stat5b DNA binding. Am J Physiol Endocrinol Metab 2007; 292: E1856-E1862.
    • (2007) Am J Physiol Endocrinol Metab , vol.292
    • Chen, Y.1    Sun, D.2    Krishnamurthy, V.M.3
  • 41
    • 29244475380 scopus 로고    scopus 로고
    • Serum albumin, C-reactive protein, interleukin-6, and fetuin a as predictors of malnutrition, cardiovascular disease, and mortality in patients with ESRD
    • Honda H, Qureshi AR, Heimburger O et al. Serum albumin, C-reactive protein, interleukin-6, and fetuin a as predictors of malnutrition, cardiovascular disease, and mortality in patients with ESRD. Am J Kidney Dis 2006; 47: 139-148.
    • (2006) Am J Kidney Dis , vol.47 , pp. 139-148
    • Honda, H.1    Qureshi, A.R.2    Heimburger, O.3
  • 42
    • 17444418617 scopus 로고    scopus 로고
    • Age-related differences in skeletal muscle protein synthesis: Relation to markers of immune activation
    • Toth MJ, Matthews DE, Tracy RP et al. Age-related differences in skeletal muscle protein synthesis: relation to markers of immune activation. Am J Physiol Endocrinol Metab 2005; 288: E883-E891.
    • (2005) Am J Physiol Endocrinol Metab , vol.288
    • Toth, M.J.1    Matthews, D.E.2    Tracy, R.P.3
  • 43
    • 0036087765 scopus 로고    scopus 로고
    • TNF-a impairs heart and skeletal muscle protein synthesis by altering translation initiation
    • Lang CH, Frost RA, Nairn AC et al. TNF-a impairs heart and skeletal muscle protein synthesis by altering translation initiation. Am J Physiol Endocrinol Metab 2002; 282: E336-E347.
    • (2002) Am J Physiol Endocrinol Metab , vol.282
    • Lang, C.H.1    Frost, R.A.2    Nairn, A.C.3
  • 44
    • 0035127960 scopus 로고    scopus 로고
    • Resistance exercise decreases skeletal muscle tumor necrosis factor in frail elderly humans
    • Greiwe JS, Cheng B, Rubin DC et al. Resistance exercise decreases skeletal muscle tumor necrosis factor in frail elderly humans. FASEB J 2001; 15: 475-482.
    • (2001) FASEB J , vol.15 , pp. 475-482
    • Greiwe, J.S.1    Cheng, B.2    Rubin, D.C.3
  • 45
    • 33746106471 scopus 로고    scopus 로고
    • Peripheral tissue release of Interleukin-6 in patients with chronic kidney diseases: Effects of end-stage renal disease and microinflammatory state
    • Garibotto G, Sofia A, Procopio V et al. Peripheral tissue release of Interleukin-6 in patients with chronic kidney diseases: effects of end-stage renal disease and microinflammatory state. Kidney Int 2006; 70: 384-390.
    • (2006) Kidney Int , vol.70 , pp. 384-390
    • Garibotto, G.1    Sofia, A.2    Procopio, V.3
  • 46
    • 0015256850 scopus 로고
    • Estimation of arterial PO2, PCO2, pH and lactate from arterialized venous blood
    • Forster HV, Dempsey JA, Thomson J et al. Estimation of arterial PO2, PCO2, pH and lactate from arterialized venous blood. J Appl Physiol 1971; 32: 134-137.
    • (1971) J Appl Physiol , vol.32 , pp. 134-137
    • Forster, H.V.1    Dempsey, J.A.2    Thomson, J.3
  • 48
    • 0033574249 scopus 로고    scopus 로고
    • A more accurate method to estimate glomerular filtration rate from serum creatinine: A new prediction equation. Modification of Diet in Renal Disease Study Group
    • Levey AS, Bosch JP, Lewis JB et al. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med 1999; 130: 461-470.
    • (1999) Ann Intern Med , vol.130 , pp. 461-470
    • Levey, A.S.1    Bosch, J.P.2    Lewis, J.B.3
  • 49
    • 0020404745 scopus 로고
    • Anthropometric measurement of muscle mass: Revised equations for calculating bone-free arm muscle area
    • Heymsfield SB, Mc Manus C, Smith J et al. Anthropometric measurement of muscle mass: revised equations for calculating bone-free arm muscle area. Am J Clin Nutr 1982; 36: 680-690.
    • (1982) Am J Clin Nutr , vol.36 , pp. 680-690
    • Heymsfield, S.B.1    Mc Manus, C.2    Smith, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.