Sleep deprivation decreases binding of [11C]raclopride to dopamine D2/D3 receptors in the human brain

Journal of Neuroscience

Volumn 28, Issue 34, 2008, Pages 8454-8461

  Volkow, Nora D ^a,b   Wang, Gene Jack ^c   Telang, Frank ^b   Fowler, Joanna S ^c   Logan, Jean ^c   Wong, Christopher ^c   Ma, Jim ^b   Pradhan, Kith ^c   Tomasi, Dardo ^c   Thanos, Peter K ^b   Ferré, Sergi ^a   Jayne, Millard ^b  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^b NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^c BROOKHAVEN NATIONAL LABORATORY   (United States)

Author keywords

Circadian rhythms; Dopamine transporters; PET; Striatum; Thalamus; Visual attention

Indexed keywords

CARBON 11; COCAINE; DOPAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE TRANSPORTER; RACLOPRIDE C 11; DOPAMINE RECEPTOR BLOCKING AGENT; DOPAMINE UPTAKE INHIBITOR; RACLOPRIDE;

ADULT; ARTICLE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC SYSTEM; DRUG BINDING; ELECTROENCEPHALOGRAM; FATIGUE; HUMAN; HUMAN EXPERIMENT; NEUROTRANSMISSION; NORMAL HUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SLEEP DEPRIVATION; SOMNOLENCE; THALAMUS; VISION; AROUSAL; BRAIN; MALE; METABOLISM; PATHOPHYSIOLOGY; PSYCHOLOGICAL ASPECT; SCINTISCANNING;

ADULT; AROUSAL; BRAIN; COCAINE; COGNITION DISORDERS; CORPUS STRIATUM; DOPAMINE; DOPAMINE ANTAGONISTS; DOPAMINE UPTAKE INHIBITORS; FATIGUE; HUMANS; MALE; POSITRON-EMISSION TOMOGRAPHY; RACLOPRIDE; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D3; SLEEP DEPRIVATION; THALAMUS;

EID: 51649131485     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1443-08.2008     Document Type: Article

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