Impact of genetic and epigenetic factors from early life to later disease

Metabolism: Clinical and Experimental

Volumn 57, Issue SUPL.2, 2008, Pages

  Tremblay, Johanne ^a   Hamet, Pavel ^a  

^a Centre Hospitalier   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTATION; ARTICLE; CHILD GROWTH; CHILDHOOD; CHRONIC DISEASE; DISEASE COURSE; ENVIRONMENT; EPIGENETICS; GENETIC SUSCEPTIBILITY; GENOTYPE; HEREDITY; HUMAN; LIFE; MODULATION; MOLECULAR EVOLUTION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ANIMALS; CHILD; CHILD DEVELOPMENT; DIABETES MELLITUS, TYPE 2; EPIGENESIS, GENETIC; FEMALE; FETAL DEVELOPMENT; GENETIC DISEASES, INBORN; GENETIC PREDISPOSITION TO DISEASE; GENOMIC IMPRINTING; HUMANS; INFANT; MODELS, BIOLOGICAL; PREGNANCY;

EID: 51649130688     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.metabol.2008.07.012     Document Type: Article

References (35)

1. The conceptual basis for the developmental origins of health and disease. In: Gluckman P.A., and Hanson M. (Eds). Developmental origins of health and disease (2006), Cambridge University Press 33-50
2. Ridley M. Nature via nurture: genes, experience, and what makes us human (2003)
3. Hales C.N., and Barker D.J.P. Type-2 (non-insulin-dependent) diabetes-mellitus-the thrifty phenotype hypothesis. Diabetologia 35 (1992) 595-601
4. Lindsay R., and Bennett P.H. Type 2 diabetes, the thrifty phenotype-an overview. Br Med Bull 60 (2001) 21-32
5. Lawlor D.A., and Smith G.D. Early life determinants of adult blood pressure. Curr Opin Nephrol Hypertens 14 (2005) 259-264
6. Leeson C.P.M., Kattenhorn M., Morley R., et al. Impact of low birth weight and cardiovascular risk factors on endothelial function in early adult life. Circulation 103 (2001) 1264-1268
7. Lenfant C. Low birth weight and blood pressure. Metabolism (2008) [this issue]
8. McMillen I.C., Adam C.L., and Muhlhausler B.S. Early origins of obesity: programming the appetite regulatory system. J Physiol-London 565 (2005) 9-17
9. Plante G.E. Pre-disease biological markers: early diagnosis and cure of arterial hypertension. Metabolism (2008) [this supplement]
10. Dasgupta K., O'Loughlin J., Chen S.F., et al. Emergence of sex differences in prevalence of high systolic blood pressure-analysis of a longitudinal adolescent cohort. Circulation 114 (2006) 2663-2670
11. Wells J.C.K. The thrifty phenotype as an adaptive maternal effect. Biol Rev 82 (2007) 143-172
12. Sedova L., Seda O., Kazdova L., et al. Sucrose feeding during pregnancy and lactation elicits distinct metabolic response in offspring of an inbred genetic model of metabolic syndrome. Am J Physiol-Endocrinol Metabol 292 (2007) E1318-E1324
13. Dulloo A.G., Jacquet J., Seydoux J., et al. The thrifty 'catch-up fat' phenotype: its impact on insulin sensitivity during growth trajectories to obesity and metabolic syndrome. Int J Obes 30 (2006) S23-S35
14. Khan I., Dekou V., Hanson M., et al. Predictive adaptive responses to maternal high-fat diet prevent endothelial dysfunction but not hypertension in adult rat offspring. Circulation 110 (2004) 1097-1102
15. Hoet J.J., Ozanne S., and Reusens B. Influences of pre- and postnatal nutritional exposures on vascular/endocrine systems in animals. Environ Health Perspect 108 (2000) 563-568
16. Neel J.V. Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"?. Bull World Health Organ 77 (1999) 353-362
17. Sladek R., Rocheleau G., Rung J., et al. A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 445 (2007) 881-885
18. Scott L.J., Mohlke K.L., Bonnycastle L.L., et al. A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 316 (2007) 1341-1345
19. Helgason A., Pálsson S., Thorleifsson G., et al. Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution. Nat Genet 39 (2007) 218-225
20. Pausova Z., Gossard F., Gaudet D., et al. Familial resemblance of obesity measures in hypertensive pedigrees of French-Canadian origin. J Hypertens 18 (2000) S21
21. Buresova M., Zidek V., Musilova A., et al. Genetic relationship between placental and fetal weights and markers of the metabolic syndrome in rat recombinant inbred strains. Physiol Genomics 26 (2006) 226-231
22. Hattersley A.T., Beards F., Ballantyne E., et al. Mutations in the glucokinase gene of the fetus result in reduced birth weight. Nat Genet 19 (1998) 268-270
23. Weedon M.N., Frayling T.M., Shields B., et al. Genetic regulation of birth weight and fasting glucose by a common polymorphism in the islet cell promoter of the glucokinase gene. Diabetes 54 (2005) 576-581
24. Weedon M.N., Clark V.J., Qian Y.D., et al. A common haplotype of the glucokinase gene alters fasting glucose and birth weight: association in six studies and population-genetics analyses. Am J Hum Genet 79 (2006) 991-1001
25. Eriksson J.G., Lindi V., Uusitupa M., et al. The effects of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma 2 gene on insulin sensitivity and insulin metabolism interact with size at birth. Diabetes 51 (2002) 2321-2324
26. Wang L., Wang X.B., Laird N., et al. Polymorphism in maternal LRP8 gene is associated with fetal growth. Am J Hum Genet 78 (2006) 770-777
27. Stoger R. The thrifty epigenotype: an acquired and heritable predisposition for obesity and diabetes?. Bioessays 30 (2008) 156-166
28. Paradies Y.C., Montoya M.J., and Fullerton S.M. Racialized genetics and the study of complex diseases-the thrifty genotype revisited. Perspect Biol Med 50 (2007) 203-227
29. Tost J. Epigenetics (2008)
30. Whitelaw E., and Garrick D. Epigenetic mechanisms. In: Gluckman P.D., and Hanson M.A. (Eds). Developmental origins of health and disease (2006), Cambridge University Press 62-74
31. Noer A., Sorensen A.L., Boquest A.C., et al. Stable CpG hypomethylation of adipogenic promoters in freshly isolated, cultured, and differentiated mesenchymal stem cells from adipose tissue. Mol Biol Cell 17 (2006) 3543-3556
32. Stoger R. In vivo methylation patterns of the Leptin promoter in human and mouse. Epigenetics (2006) 155-162
33. Weaver I.C., Cervoni N., Champagne F.A., et al. Epigenetic programming by maternal behavior. Nat Neurosci 7 (2004) 847-854
34. Weaver I.C. Epigenetic programming by maternal behavior and pharmacological intervention. Nature versus nurture: let's call the whole thing off. Epigenetics 2 (2007) 22-28
35. Enattah N.S., Jensen T.G.K., Nielsen M., et al. Independent introduction of two lactase-persistence alleles into human populations reflects different history of adaptation to milk culture. Am J Hum Genet 82 (2008) 57-72