Type 2 diabetes, the thrifty phenotype - An overview

British Medical Bulletin

Volumn 60, Issue , 2001, Pages 21-32

  Lindsay, Robert S ^a   Bennett, Peter H ^a  

^a Digestive and Kidney Diseases   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIRTH WEIGHT; DIABETES MELLITUS; ENVIRONMENTAL FACTOR; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PHENOTYPE; PRIORITY JOURNAL; REVIEW; RISK FACTOR;

DIABETES MELLITUS, TYPE 2; ENVIRONMENT; GENOTYPE; HUMANS; PHENOTYPE;

EID: 0035706020     PISSN: 00071420     EISSN: None     Source Type: Journal    
DOI: 10.1093/bmb/60.1.21     Document Type: Review

References (45)

1. Diabetes mellitus. Report of a WHO study group
2. The rising global burden of diabetes and its complications: Estimates and projections to the year 2010
3. Glucose transporters and insulin action - Implications for insulin resistance and diabetes mellitus
4. Leptin and the regulation of body weight in mammals
5. Maturity-onset diabetes of the young: Clinical heterogeneity explained by genetic heterogeneity
6. Congenital leptin deficiency is associated with severe early-onset obesity in humans
7. A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
8. Obesity: Preventing and managing the global epidemic. Report of a WHO consultation
9. Type 2 (non-insulin-dependent) diabetes mellitus: The thrifty phenotype hypothesis
10. Review: Rise and fall of western diseases
11. Fetal and infant growth and impaired glucose tolerance at age 64
12. The thrifty phenotype hypothesis: How does it look after 5 years?
13. Association of low birth weight with beta cell function in the adult first degree relatives of non-insulin dependent diabetic subjects
14. Thinness at birth and insulin resistance in adult life
15. Diabetes mellitus: A thrifty genotype rendered detrimental by 'progress'
16. The 'thrifty genotype' in 1998
17. Diabetes mellitus in the Pima Indians: Incidence, risk factors and pathogenesis
18. Programming by early nutrition in man
19. Childhood diabetes: Its course and influence in the second and third generations
20. Weight and length at birth in infants of diabetic mothers
21. Banting lecture 1980. Of pregnancy and progeny
22. Excessive obesity in offspring of Pima Indian women with diabetes during pregnancy
23. Congenital susceptibility to NIDDM. Role of intrauterine environment
24. Evidence for a sensitive period in adipose-cell replication in man
25. Obesity in young men after famine exposure in utero and early infancy
26. Effects of low dosages of androgens on the differentiation of hypothalamic regulatory control of ovulation in the rat
27. Sex hormones, brain development and brain function
28. Breastfeeding and incidence of non-insulin-dependent diabetes mellitus in Pima Indians
29. Breast feeding and obesity: Cross sectional study
30. The fetal insulin hypothesis: An alternative explanation of the association of low birthweight with diabetes and vascular disease
31. The various faces of diabetes in the young: Changing concepts
32. Mutations in the glucokinase gene of the fetus result in reduced birth weight
33. Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1
34. Variability of the insulin receptor substrate-1, hepatocyte nuclear factor-1alpha (HNF-1alpha), HNF-4alpha, and HNF-6 genes and size at birth in a population-based sample of young Danish subjects
35. Birth weight and non-insulin dependent diabetes: Thrifty genotype, thrifty phenotype, or surviving small baby genotype?
36. Obesity in offspring of diabetic Pima Indian women despite normal birth weight
37. Type 2 diabetes and low birth weight: The role of paternal inheritance in the association of low birth weight and diabetes
38. Genomic imprinting: Implications for human disease
39. A catalogue of imprinted genes and parent-of-origin effects in humans and animals
40. Analysis of parent-offspring trios provides evidence for linkage and association between the insulin gene and type 2 diabetes mediated exclusively through paternally transmitted class III variable number tandem repeat alleles
41. Low birth weight is associated with NIDDM in discordant monozygotic and dizygotic twin pairs
42. Testing the fetal origins hypothesis in twins: The Birmingham twin study
43. Glucose tolerance in adults after prenatal exposure to famine
44. Prenatal glucocorticoid exposure leads to offspring hyperglycaemia in the rat: Studies with the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone