Epigenetic mechanisms

Developmental Origins of Health and Disease

Volumn , Issue , 2006, Pages 62-74

  Whitelaw, Emma ^a,b   Garrick, David ^c  

^a UNIVERSITY OF SYDNEY   (Australia)

^b QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84857783016     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1017/CBO9780511544699.006     Document Type: Chapter

References (68)

1. Amir, R.E., Van denVeyver, I. B., Wan, M., Tran, C.Q., Francke, U. and Zoghbi, H. Y. (1999). Rett syndrome iscausedbymuta- tions in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat. Genet., 23, 185-8.
2. Bachman, K. E., Park, B. H., Rhee, I. et al. (2003). Histonemodifi- cations and silencing prior to DNA methylation of a tumor suppressor gene. Cancer Cell, 3, 89-95.
3. Ballestar, E. and Wolffe, A. P (2001). Methyl-CpG-binding proteins: targeting specific gene repression. Eur. J. Biochem., 268, 1-6.
4. Belyaev, N., Keohane, A. M. and Turner, B. M. (1996).Differential underacetylation of histones H2A, H3 and H4 on the inac- tiveXchromosome in human female cells. Hum. Genet., 97, 573-8.
5. Boggs, B.A., Cheung, P, Heard, E., Spector, D. L., Chinault, A. C. and Allis, C. D. (2002). Differentially methylated forms of histone H3 show unique association patterns with inactive human X chromosomes. Nat. Genet., 30, 73-6.
6. Cooney, C. A., Dave, A. A. and Wolff, G. L. (2002). Maternal methyl supplements in mice affect epigenetic variation and DNA methylation of offspring. J. Nutr., 132, 2393S-400S.
7. Engel, J. R., Smallwood, A., Harper, A. et al. (2000). Epigenotype- phenotype correlations in Beckwith-Wiedemann syndrome. J. Med. Genet., 37, 921-6.
8. Gama-Sosa, M. A., Slagel, V. A., Trewyn, R. W. et al. (1983). The 5-methylcytosine content of DNA from human tumors. Nucleic Acids Res., 11, 6883-94.
9. Gibbons, R. J. and Higgs, D. R. (2000). Molecular-clinical spectrum of the ATR-X syndrome. Am. J. Med. Genet., 97, 204-12.
10. Grandjean, V., O’Neill, L., Sado, T., Turner, B. and Ferguson- Smith, A. (2001). Relationship between DNA methylation, histone H4 acetylation and gene expression in the mouse imprinted Igf2-H19 domain. FEBSLett., 488, 165-9.
11. Greger, V., Passarge, E., Hopping, W., Messmer, E. and Hors- themke, B. (1989). Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma. Hum. Genet., 83, 155-8.
12. Hajkova, P., Erhardt, S., Lane, N. et al. (2002). Epigenetic reprogramming in mouse primordial germ cells. Mech. Dev., 117, 15-23.
13. Hake, S. B., Xiao, A. and Allis, C. D. (2004). Linking the epigenetic ‘language’ of covalent histone modifications to cancer. Br. J. Cancer, 90, 761-9.
14. Hark, A. T., Schoenherr, C. J., Katz, D. J., Ingram, R. S., Lev- orse, J. M. and Tilghman, S. M. (2000). CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus. Nature, 405, 486-9.
15. Hata, K., Okano, M., Lei, H. and Li, E. (2002). Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice. Development, 129, 1983-93.
16. Holliday, R. and Pugh, J. E. (1975). DNA modification mechanisms and gene activity during development. Science, 187, 226-32.
17. Hong, L., Schroth, G. P., Matthews, H. R., Yau, P. and Brad- bury, E. M. (1993).Studies of the DNA binding properties of histone H4 amino terminus: thermal denaturation studies reveal that acetylation markedly reduces the binding constant of the H4 ‘tail’ to DNA. J. Biol. Chem., 268, 305-14.
18. Huang, C., Sloan, E. A. and Boerkoel, C. F. (2003). Chromatin remodeling and human disease. Curr. Opin. Genet. Dev., 13, 246-52.
19. Issa, J. P, Garcia-Manero, G., Giles, F. J. et al. (2004). Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2’-deoxycytidine (decitabine) in hematopoietic malignancies. Blood, 103, 1635-40.
20. Kaneda, M., Okano, M., Hata, K. et al. (2004). Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting. Nature, 429, 900-3.
21. Kang, Y. K., Koo, D. B., Park, J. S. et al. (2001). Aberrant methyl- ation of donor genome in cloned bovine embryos. Nat. Genet., 28, 173-7.
22. Kelly, W. K., Richon, V M., O’Connor, O. et al. (2003). Phase I clinical trial of histone deacetylase inhibitor: suberoylanilide hydroxamic acid administered intravenously. Clin. Cancer. Res., 9, 3578-88.
23. Kirmizis, A., Bartley, S. M., Kuzmichev, A. et al. (2004). Silencing of human polycomb target genes is associatedwith methyl- ation of histone H3 Lys 27. GenesDev., 18, 1592-1605.
24. Knudson, A. G., Jr. (1971). Mutation and cancer: statistical study of retinoblastoma. Proc. Natl. Acad. Sci. USA, 68, 820-3.
25. Lachner, M. and Jenuwein, T. (2002). The many facesof histone lysine methylation. Curr. Opin. Cell. Biol., 14, 286-98.
26. Li, E., Bestor, T. H. and Jaenisch, R. (1992). Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell, 69, 915-26.
27. Lusser, A. and Kadonaga, J. T. (2003). Chromatin remodeling by ATP-dependent molecular machines. Bioessays, 25, 1192-1200.
28. Mann, M. R., Chung, Y. G., Nolen, L. D., Verona, R. I., Latham, K. E. and Bartolomei, M. S. (2003). Disruption of imprinted gene methylation and expression in cloned preimplantation stage mouse embryos. Biol. Reprod., 69, 902-14.
29. McDowell, T. L., Gibbons, R. J., Sutherland, H. et al. (1999). Localization of a putative transcriptional regulator (ATRX) at pericentromeric heterochromatin and the short arms of acrocentric chromosomes. Proc. Natl. Acad. Sci. USA, 96, 13983-8.
30. McGrath, J. and Solter, D. (1984). Completionofmouseembryo- genesis requires both the maternal and paternal genomes. Cell, 37, 179-83.
31. Meaney, M. J. (2001). Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations. Annu. Rev. Neurosci., 24, 1161-92.
32. Monk, M., Boubelik, M. and Lehnert, S. (1987). Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development. Development, 99, 371-82.
33. Morgan, H. D., Sutherland, H. G., Martin, D. I. and Whitelaw, E. (1999). Epigenetic inheritance at the agouti locus in the mouse. Nat. Genet., 23, 314-18.
34. Morison, I. M. and Reeve, A. E. (1998).A catalogue of imprinted genes and parent-of-origin effects in humans and animals. Hum. Mol. Genet., 7, 1599-1609.
35. Murata, T., Kurokawa, R., Krones, A. et al. (2001). Defect of histone acetyltransferase activityof the nuclear transcriptional coactivator CBP in Rubinstein-Taybi syndrome. Hum. Mol. Genet., 10, 1071-6.
36. Narlikar, G.J., Fan, H. Y. and Kingston, R.E. (2002). Cooperation between complexes that regulate chromatin structure and transcription. Cell, 108, 475-87.
37. Nicholls, R. D., Saitoh, S. and Horsthemke, B. (1998). Imprinting in Prader-Willi and Angelman syndromes. Trends Genet., 14, 194-200.
38. Nowak, S. J. and Corces, V. G. (2004). Phosphorylation of histone H3: a balancing act between chromosome condensation and transcriptional activation. Trends Genet., 20, 214-20.
39. Ogonuki, N., Inoue, K., Yamamoto, Y. et al. (2002). Early death of mice cloned from somatic cells. Nat. Genet., 30, 253-4.
40. Okano, M., Bell, D. W., Haber, D. A. and Li, E. (1999).DNA methyl- transferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell, 99, 24757.
41. Oswald, J., Engemann, S., Lane, N. et al. (2000). Active demethyl- ation of the paternal genome in the mouse zygote. Curr. Biol., 10, 475-8.
42. Plath, K., Fang, J., Mlynarczyk-Evans, S. K. et al. (2003). Role of histone H3 lysine 27 methylation in Xinactivation. Science, 300, 131-5.
43. Pradhan, S., Bacolla, A., Wells, R. D. and Roberts, R. J. (1999). Recombinant human DNA (cytosine-5) methyltransferase. I. Expression, purification, and comparison of de novo and maintenance methylation. J. Biol. Chem., 274, 33002-10.
44. Qu, G. Z., Grundy, P E., Narayan, A. and Ehrlich, M. (1999). Frequent hypomethylation in Wilms tumors of pericen- tromeric DNA in chromosomes 1 and 16. Cancer Genet. Cytogenet., 109, 34-9.
45. Rakyan, V K., Blewitt, M. E., Druker, R., Preis, J. I. and Whitelaw, E. (2002). Metastable epialleles in mammals. Trends Genet., 18, 348-51.
46. Rhind, S. M., Taylor, J. E., De Sousa, P. A., King, T. J., McGarry, M. and Wilmut, I. (2003). Human cloning: can itbe made safe? Nat. Rev. Genet., 4, 855-64.
47. Roberts, C. W. and Orkin, S. H. (2004). The SWI/SNF complex: chromatin and cancer. Nat. Rev. Cancer, 4, 133-42.
48. Sado, T., Fenner, M. H., Tan, S. S., Tam, P., Shioda, T. and Li, E. (2000). X inactivation in the mouse embryo deficient for Dnmt1: distinct effect of hypomethylation on imprinted and random X inactivation. Dev. Biol., 225, 294-303.
49. Santos, F., Hendrich, B., Reik, W. and Dean, W. (2002). Dynamic reprogramming of DNA methylation in the early mouse embryo. Dev. Biol., 241, 172-82.
50. Santos, F., Zakhartchenko, V., Stojkovic, M. et al. (2003). Epigenetic marking correlates with developmental potential in clonedbovine preimplantation embryos. Curr. Biol., 13, 1116-21.
51. Santos-Rosa, H., Schneider, R., Bannister, A. J. et al. (2002). Active genes are tri-methylated at K4 of histone H3. Nature, 419, 407-11.
52. Sassone-Corsi, P, Mizzen, C. A., Cheung, P. et al. (1999). Require- mentof Rsk-2 for epidermal growth factor- activated phosphorylation of histone H3. Science, 285, 886-91.
53. Shaker, S., Bernstein, M., Momparler, L. F. and Momparler, R. L. (2003). Preclinical evaluation of antineoplastic activity of inhibitors of DNA methylation (5-aza-2’-deoxycytidine) and histone deacetylation (trichostatin A, depsipeptide) in combination against myeloid leukemic cells. Leuk. Res., 27, 437-44.
54. Shiio, Y. and Eisenman, R. N. (2003). Histone sumoylation is associated with transcriptional repression. Proc. Natl. Acad. Sci. USA, 100, 13225-30.
55. Silva, J., Mak, W., Zvetkova, I. et al. (2003). Establishmentof his- tone h3 methylation on the inactive Xchromosome requires transient recruitment of Eed-Enx1 polycomb group complexes. Dev. Cell, 4, 481-95.
56. Strahl, B. D. and Allis, C. D. (2000). The language of covalent histone modifications. Nature, 403, 41-5.
57. Tamashiro, K. L., Wakayama, T., Akutsu, H. et al. (2002). Cloned mice have an obese phenotype not transmitted to their offspring. Nat. Med., 8, 262-7.
58. Thorvaldsen, J. L., Duran, K. L. and Bartolomei, M. S. (1998). Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2. GenesDev., 12, 3693-702.
59. Vasques, L. R., Klockner, M. N. and Pereira, L. V (2002). X chromosome inactivation: how human are mice? Cytogenet. Genome Res., 99, 30-5.
60. Walsh, C. P and Bestor, T. H. (1999). Cytosine methylation and mammalian development. Genes Dev., 13, 26-34.
61. Waterland, R.A. and Jirtle, R. L. (2003).Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol. Cell. Biol., 23, 5293-5300.
62. Weaver, I. C., Cervoni, N., Champagne, F. A. et al. (2004). Epigenetic programming by maternal behavior. Nat. Neurosci., 7, 847-54.
63. Wolff, G. L., Kodell, R. L., Moore, S. R. and Cooney, C. A. (1998). Maternal epigenetics and methyl supplements affect agouti gene expression in Avy/a mice. Faseb. J., 12, 949-57.
64. Wrenzycki, C., Lucas-Hahn, A., Herrmann, D., Lemme, E., Kor- sawe, K. and Niemann, H. (2002). In vitro production and nuclear transfer affect dosage compensation of the X-linked gene transcripts G6PD, PGK, and Xist in preimplantation bovine embryos. Biol. Reprod., 66, 127-34.
65. Xu, G. L., Bestor, T. H., Bourc’his, D. et al. (1999). Chromosome instability and immunodeficiency syndrome caused bymutations inaDNAmethyltransferase gene. Nature, 402, 187-91.
66. Xue, Y., Gibbons, R., Yan, Z. et al. (2003). TheATRXsyndromepro- teinformsachromatin-remodeling complex with Daxxand localizes in promyelocytic leukemia nuclear bodies. Proc. Natl. Acad. Sci. USA, 100, 10635-40.
67. Yoder, J. A., Walsh, C. P. and Bestor, T. H. (1997). Cytosine methyl- ation and the ecology of intragenomic parasites. Trends Genet., 13, 335-40.
68. Zhang, Y. (2003). Transcriptional regulation by histone ubiquitination and deubiquitination. Genes Dev., 17, 2733-40.