DNA hypermethylation of PITX2 is a marker of poor prognosis in untreated lymph node-negative hormone receptor-positive breast cancer patients

Breast Cancer Research and Treatment

Volumn 111, Issue 3, 2008, Pages 429-437

  Nimmrich, Inko ^a   Sieuwerts, Anieta M ^b   Meijer Van Gelder, Marion E ^b   Schwope, Ina ^a   Bolt De Vries, Joan ^b   Harbeck, Nadia ^c   Koenig, Thomas ^a   Hartmann, Oliver ^a   Kluth, Antje ^a   Dietrich, Dimo ^a   Magdolen, Viktor ^c   Portengen, Henk ^b   Look, Maxime P ^b   Klijn, Jan G M ^b   Lesche, Ralf ^a   Schmitt, Manfred ^c   Maier, Sabine ^a   Foekens, John A ^b   Martens, John W M ^b  

^a EPIGENOMICS AG   (Germany)

^b JOSEPHINE NEFKENS INSTITUTE   (Netherlands)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Breast cancer; DNA methylation; Estrogen receptor; PITX2; Prognosis

Indexed keywords

MESSENGER RNA; STEROID RECEPTOR; TRANSCRIPTION FACTOR PITX2;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER GRADING; CANCER GROWTH; CANCER RECURRENCE; DISTANT METASTASIS; DNA METHYLATION; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; TUMOR VOLUME;

ADULT; AGED; BREAST NEOPLASMS; CELL LINE, TUMOR; DNA METHYLATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HOMEODOMAIN PROTEINS; HUMANS; LYMPH NODES; MIDDLE AGED; NEOPLASM METASTASIS; PROGNOSIS; RECEPTORS, STEROID; RETROSPECTIVE STUDIES; RNA, MESSENGER; SURVIVAL ANALYSIS; TIME FACTORS; TRANSCRIPTION FACTORS; TUMOR MARKERS, BIOLOGICAL;

EID: 51649095103     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10549-007-9800-8     Document Type: Article

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