Inhibitors of GSK-3 prevent corticosterone from inducing COX-1 expression in cardiomyocytes

Cardiovascular Toxicology

Volumn 8, Issue 2, 2008, Pages 93-100

  Sun, Haipeng ^a,b   Chen, Qin M ^c  

^a UNIVERSITY OF ARIZONA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

Corticosteroids; Cyclooxygenase; Glycogen synthase kinases; Pharmacological inhibitors; Transcription

Indexed keywords

2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; 6 BROMOINDIRUBIN 3'OXIME; CORTICOSTERONE; CYCLOOXYGENASE 1; GLUCOCORTICOID RECEPTOR; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; LITHIUM CHLORIDE; OXIME DERIVATIVE; UNCLASSIFIED DRUG; 6 BROMOINDIRUBIN 3' OXIME; 6-BROMOINDIRUBIN-3'-OXIME; CYCLOOXYGENASE 2; INDOLE DERIVATIVE; MALEIMIDE DERIVATIVE; MEMBRANE PROTEIN; OXIME; PROTEIN KINASE INHIBITOR; PTGS1 PROTEIN, RAT; PTGS2 PROTEIN, RAT; SP3 PROTEIN, RAT; TRANSCRIPTION FACTOR SP3;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENETIC TRANSCRIPTION; HEART MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; RAT; ANIMAL; BIOSYNTHESIS; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; ENZYME INDUCTION; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; METABOLISM; NEWBORN; PHOSPHORYLATION; PROMOTER REGION; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; CORTICOSTERONE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; ENZYME INDUCTION; GLYCOGEN SYNTHASE KINASE 3; INDOLES; LITHIUM CHLORIDE; MALEIMIDES; MEMBRANE PROTEINS; MYOCYTES, CARDIAC; OXIMES; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PROTEIN KINASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GLUCOCORTICOID; SP3 TRANSCRIPTION FACTOR; TRANSFECTION;

EID: 51449088620     PISSN: 15307905     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12012-008-9018-y     Document Type: Article

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