Transcriptional regulation of endothelial constitutive PGHS-1 expression by phorbol ester

American Journal of Physiology - Cell Physiology

Volumn 270, Issue 1 39-1, 1996, Pages

  Xu, Xiao Ming ^a   Tang, Jih Luh ^a   Hajibeigi, Asghar ^a   Loose Mitchell, David S ^a   Wu, Kenneth K ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

cyclooxygenase; human endothelial cells; prostacyclin biosynthesis; type 1 prostaglandin H synthase induction

Indexed keywords

ISOENZYME; MESSENGER RNA; PHORBOL ESTER; PROSTAGLANDIN SYNTHASE;

ARTICLE; ENDOTHELIUM CELL; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RNA ANALYSIS; TRANSCRIPTION REGULATION;

EID: 0030039894     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1996.270.1.c259     Document Type: Article

References (29)

1. Chirgwin, J. M., A. E. Przybyla, R. J. McDonald, and W. J. Rutler. Isolation of biologically active RNA from sources enriched in ribonucleases. Biochemistry 18: 5294-5299, 1979.
2. DeWitt, D. L., and E. A. Meade. Serum and glucocorticoid regulation of gene transcription and expression of the prostaglandin H synthase-1 and -2 isozymes. Arch. Biochem. Biophys. 306: 94-102, 1993.
3. DeWitt, D. L., and W. L. Smith. Primary structure of prostaglandin G/H synthase from the sheep seminal vesicular gland determined from the complementary DNA sequence. Proc. Natl. Acad. Sci. USA 85: 1412-1416, 1988.
4. Funk, C. D., L. B. Funk, M. E. Kennedy, A. S. Pong, and G.A. Fitzgerald. Human platelet/erythroleukemia cell prostaglandin G/H synthase: cDNA cloning, expression and gene chromosome assignment. FASEB J. 5: 2304-2312, 1991.
5. Hemler, M., and W. E. M. Lands. Purification of the cyclooxygenase that forms prostaglandins. J. Biol. Chem. 251: 5575-5579, 1976.
6. Hla, T., and K. Nielsen. Human cyclooxygenase-2 cDNA. Proc. Natl. Acad. Sci. USA 89: 7384-7358, 1992.
7. Jaffe, E. A., R. L. Nachman, C. G. Becker, and C. R. Minick. Culture of human endothelial cells derived from umbilical veins. J. Clin. Invest. 52: 2745-2756, 1973.
8. Jones, D. A., D. P. Carlton, T. M. Mclntire, G. A. Zimmerman, and S. M. Prescott. Molecular cloning of human PGHS-2 and demonstration of expression in response to cytokines. J. Biol. Chem. 268: 9049-9054, 1993.
9. Kujubu, D. A., B. S. Fletcher, B. C. Varnum, R. W. Lim, and H. R. Herschman. TIS 10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells encodes a novel prostaglandin synthase homologue. J. Biol. Chem. 266: 12866-12872, 1991.
10. Kujubu, D. A., and H. R. Herschman. Dexamethasone inhibits mitogen induction of the TIS 10 prostaglandin synthase/ cyclooxygenase gene. J. Biol. Chem. 267: 7991-7994, 1992.
11. Merlie, J. P., D. Fagan, J. Mudd, and P. Needleman. Isolation and characterization of the complementary DNA for sheep seminal vesicle prostaglandin endoperoxide synthase. J. Biol. Chem. 263: 3550-3553, 1988.
12. Miyamoto, T., N. Ogino, S. Yamamoto, and O. Hayaishi. Purification of prostaglandin endoperoxide synthetase from bovine vesicular gland microsomes. J. Biol. Chem. 251: 2629-2636, 1976.
13. Nordeen, S. K. Luciferase reporter gene vectors for analysis. Biotechnology 6: 454-458, 1988.
14. O'Banion, M. K., V. D. Winn, and D. A. Yonng. cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase. Proc. Natl. Acad. Sci. USA 89: 4888-4892, 1992.
15. O'Sullivan, M. G., F. H. Chilton, E. M. Huggins, and C. E. McCall. Lipopolysaccharide priming of alveolar macrophages for enhanced synthesis of prostaglandins involves induction of a novel PGH synthase. J. Biol. Chem. 267: 14547-14550, 1992.
16. Sambrook, J., E. F. Fritsch, and T. Maniatis. Mapping of RNA With Ribonuclease and Radiolabeled RNA Probes. Cold Spring Harbor, NY: Cold Spring Harbor, 1989, p. 7.71-7.74.
17. Sanduja, S. K., A.-L. Tsai, N. Matijevic-Aleksic, and K. K. Wu. Kinetics of prostacyclin synthesis in PGHS-1 overexpressed endothelial cells. Am. J. Physiol. 267 (Cell Physiol. 36): C1459-C1466, 1994.
18. Sirois, J., D. L. Simmon, and J. S. Richards. Hormonal regulation of messenger RNA encoding a novel isoform of prostaglandin endoperoxide synthase in rat preovulatory follicles. J. Biol. Chem. 267: 11586-11592, 1992.
19. Smith, W. L., L. J. Marnett, and D. L. DeWitt. Prostaglandin and thromboxane biosynthesis. Pharmacol. Ther. 49: 153-179, 1991.
20. Strauss, W. L. Complexities and sequence similarities of mRNA populations of cholinergic (NS20-Y) and adrenergic (N1E-115) murine neuroblastoma cell lines. Differentiation 44: 56-61, 1991.
21. Tazawa, R., X.-M. Xu, K. K. Wu, and L.-H. Wang. Characterization of the genomic structure, chromosomal location and promoter of human PGHS-2 gene. Biochem. Biophys. Res. Commun. 203: 190-199, 1994.
22. Wang, L.-H., A. Hajibeigi, X.-M. Xu, D. Loose-Mitchell, and K. K. Wu. Characterization of the promoter of human prostaglandin H synthase-1 gene. Biochem. Biophys. Res. Commun. 190: 406-411, 1993.
23. Wasylyk, C., P. Flores, A. Gutman, and B. Wasylyk. PEA3 is a nuclear target for transcription activation by non-nuclear oncogenes. EMBO J. 8: 3371-3378, 1989.
24. Wu, K. K., H. Hazakis, S. S. Lo, D. C. Seong, S. K. Sanduja, and H. H. Tai. Stimulation of de novo synthesis of prostaglandin G/H synthase in human endothelial cells by phorbol ester. J. Biol. Chem. 263: 19043-19047, 1988.
25. Wu, K. K., A. C. Papp, C. E. Manner, and E. R. Hall. Interaction between lymphocytes and platelets in the synthesis of prostacyclin. J. Clin. Invest. 79: 1601-1606, 1987.
26. Wu, K. K., R. Sanduja, A.-L. Tsai, B. Ferhanoglu, and D. S. Loose-Mitchell. Aspirin inhibits interleukin-1 induced prostaglandin H synthase expression in cultured endothelial cells. Proc. Natl. Acad. Sci. USA 88: 2384-2387, 1991.
27. Xie, W., J. G. Chipman, D. L. Robertson, R. L. Erikson, and D. L. Simmons. Expression of a mitogen-repressive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc. Natl. Acad. Sci. USA 88: 2692-2696, 1991.
28. Yokoyama, C., T. Takai, and T. Tanabe. Primary structure of sheep prostaglandin endoperoxide synthase deduced from cDNA sequence. FEBS Lett. 231: 347-351, 1988.
29. Zyglewska, T., L.-C. Wu, X.-M. Xu, M. G. Conlan, L.-H. Wang, and K. K. Wu, Quantitative analysis of vascular PGHS mRNA levels by competitive polymerase chain reaction. J. Lab. Clin. Med. 122: 542-548, 1993.