Efficient synthesis of antifungal pyrimidines via palladium catalyzed Suzuki/Sonogashira cross-coupling reaction from Biginelli 3,4-dihydropyrimidin-2(1H)-ones

Tetrahedron

Volumn 64, Issue 44, 2008, Pages 10214-10223

  Gholap, Atul R ^a   Toti, Kiran S ^a   Shirazi, Fazal ^a   Deshpande, Mukund V ^a   Srinivasan, Kumar V ^a  

^a NATIONAL CHEMICAL LABORATORY   (India)

Author keywords

Antifungal activities; Biginelli compounds; Chlorination; Oxidation; Pyrimidines; Suzuki coupling

Indexed keywords

[4 (2,5 DIMETHOXYPHENYL) 6 METHYL 2 (NAPHTHALEN 1 YL)PYRIMIDIN 5 YL](PHENYL)METHANONE; AMPHOTERICIN B; ANTIFUNGAL AGENT; ERYTHROMYCIN; ETHYL 2 [4 (DIMETHYLAMINO)PHENYL] 4 (2,5 DIMETHOXYPHENYL) 6 METHYLPYRIMIDINE 5 CARBOXYLATE; ETHYL 2 [4 (DIMETHYLAMINO)PHENYL] 4 (3,4,5 TRIMETHOXYPHENYL) 6 METHYLPYRIMIDINE 5 CARBOXYLATE; ETHYL 2 [4 (DIMETHYLAMINO)PHENYL] 4 (4 METHOXYPHENYL) 6 METHYLPYRIMIDINE 5 CARBOXYLATE; ETHYL 2 [4 (DIMETHYLAMINO)PHENYL] 4 METHYL 6 (3 NITROPHENYL)PYRIMIDINE 5 CARBOXYLATE; ETHYL 2 [4 (DIMETHYLAMINO)PHENYL] 4 METHYL 6 (4 TOLYLPYRIMIDINE) 5 CARBOXYLATE; ETHYL 2 [4 (DIMETHYLAMINO)PHENYL] 4 METHYL 6 PHENYLPYRIMIDINE 5 CARBOXYLATE; ETHYL 4 (3 CHLOROPHENYL) 2 [4 (DIMETHYLAMINO)PHENYL] 6 METHYLPYRIMIDINE 5 CARBOXYLATE; ETHYL 4 (3,4,5 TRIMETHOXYPHENYL) 2 [2 (4 METHOXYPHENYL)ETHYNYL] 6 METHYLPYRIMIDINE 5 CARBOXYLATE; ETHYL 4 (3,4,5 TRIMETHOXYPHENYL) 6 METHYL 2 (2 PHENYLETHYNYL)PYRIMIDINE 5 CARBOXYLATE; FLUCONAZOLE; PALLADIUM; PYRIMIDINE DERIVATIVE; PYRIMIDINONE DERIVATIVE; TETRACYCLINE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BENJAMINIELLA POITRASII; BIGINELLI REACTION; CANDIDA ALBICANS; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CATALYST; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; DEHYDROGENATION; DRUG SYNTHESIS; ESCHERICHIA COLI; FUSARIUM OXYSPORUM; HALOGENATION; INFRARED SPECTROSCOPY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SONOGASHIRA REACTION; STAPHYLOCOCCUS AUREUS; SUZUKI REACTION; YARROWIA LIPOLYTICA;

BENJAMINIELLA POITRASII; CANDIDA ALBICANS; ESCHERICHIA COLI; FILOBASIDIELLA NEOFORMANS; FUSARIUM OXYSPORUM; NEGIBACTERIA; POSIBACTERIA; STAPHYLOCOCCUS AUREUS; YARROWIA LIPOLYTICA;

EID: 51349108165     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2008.08.033     Document Type: Article

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