Neospora caninum: Antibodies directed against tachyzoite surface protein NcSRS2 inhibit parasite attachment and invasion of placental trophoblasts in vitro

Experimental Parasitology

Volumn 112, Issue 3, 2006, Pages 172-178

  Haldorson, Gary J ^a   Stanton, James B ^a   Mathison, Bruce A ^a   Suarez, Carlos E ^a   Baszler, Tim V ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Adhesion invasion assays; DMEM, Dulbecco's modified Eagle's medium; DNA, deoxyribonucleic acid; HBSS, Hanks' balanced salt solution; mAb, monoclonal antibody; Monoclonal antibodies; NcSRS2; Neospora caninum; SV40, Simian virus 40

Indexed keywords

INTERFERON; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 100 2 4 4; MONOCLONAL ANTIBODY 119 14 11 14; MONOCLONAL ANTIBODY 119 16 13 37; MONOCLONAL ANTIBODY 119 20 14 22; MONOCLONAL ANTIBODY 119 3 13 1; MONOCLONAL ANTIBODY 119 4 9 10; POLYCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; FETUS; HOST CELL; IMMUNIZATION; IN VITRO STUDY; MOLECULAR CLONING; MOUSE; NEOSPORA CANINUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TROPHOBLAST;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, PROTOZOAN; ANTIGENS, SURFACE; BLOTTING, WESTERN; CELL LINE; CERCOPITHECUS AETHIOPS; COCCIDIOSIS; DISEASE TRANSMISSION, VERTICAL; FEMALE; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; INTERFERON TYPE I; MICE; MICE, INBRED BALB C; NEOSPORA; PLACENTA; PREGNANCY; PREGNANCY PROTEINS; PROTOZOAN PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SHEEP; TRANSFECTION; TROPHOBLASTS; VERO CELLS;

ANIMALIA; NEOSPORA CANINUM; OVIS; SIMIAN VIRUS 40;

EID: 32644484729     PISSN: 00144894     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exppara.2005.11.004     Document Type: Article

References (23)

1. T.V. Baszler, W.G. Harwood, K.L. Lester, W.C. Davis, and D.P. Knowles Characterization of primary caprine microglial cells and infection with caprine arthritis-encephalitis virus Laboratory Investigation 70 1994 933 943
2. T.V. Baszler, D.P. Knowles, J.P. Dubey, J.M. Gay, B.A. Mathison, and T.F. McElwain Serological diagnosis of bovine neosporosis by Neospora caninum monoclonal antibody-based competitive inhibition enzyme-linked immunosorbent assay Journal of Clinical Microbiology 34 1996 1423 1428
3. J.C. Boothroyd, A. Hehl, L.J. Knoll, and I.D. Manger The surface of Toxoplasma: more and less International Journal for Parasitology 28 1998 3 9
4. J.P. Dubey Review of Neospora caninum and neosporosis in animals Korean Journal of Parasitology 41 2003 1 16
5. J.P. Dubey, J.L. Carpenter, C.A. Speer, M.J. Topper, and A. Uggla Newly recognized fatal protozoan disease of dogs Journal of the American Veterinary Medical Association 192 1988 1269 1285
6. E.A. Ferro, E. Bevilacqua, S. Favoreto-Junior, D.A. Silva, R.A. Mortara, and J.R. Mineo Calomys callosus (Rodentia: Cricetidae) trophoblast cells as host cells to Toxoplasma gondii in early pregnancy Parasitology Research 85 1999 647 654
7. E. Gootwine Placental hormones and fetal-placental development Animal Reproductive Science 82-83 2004 551 566
8. G.J. Haldorson, B.A. Mathison, K. Wenberg, P.A. Conrad, J.P. Dubey, A.J. Trees, I. Yamane, and T.V. Baszler Immunization with native surface protein NcSRS2 induces a Th2 immune response and reduces congenital Neospora caninum transmission in mice International Journal for Parasitology 35 2005 1407 1415
9. D.K. Howe, A.C. Crawford, D. Lindsay, and L.D. Sibley The p29 and p35 immunodominant antigens of Neospora caninum tachyzoites are homologous to the family of surface antigens of Toxoplasma gondii Infection and Immunity 66 1998 5322 5328
10. A. Jacquet, L. Coulon, J. De Neve, V. Daminet, M. Haumont, L. Garcia, A. Bollen, M. Jurado, and R. Biemans The surface antigen SAG3 mediates the attachment of Toxoplasma gondii to cell-surface proteoglycans Molecular and Biochemical Parasitology 116 2001 35 44
11. C. Jung, C.Y. Lee, and M.E. Grigg The SRS superfamily of Toxoplasma surface proteins International Journal for Parasitology 34 2004 285 296
12. C. Lekutis, D.J. Ferguson, M.E. Grigg, M. Camps, and J.C. Boothroyd Surface antigens of Toxoplasma gondii: variations on a theme International Journal for Parasitology 31 2001 1285 1292
13. M.T. Long, and T.V. Baszler Fetal loss in BALB/C mice infected with Neospora caninum Journal of Parasitology 82 1996 608 611
14. A. Lunden, S. Wright, J.E. Allen, and D. Buxton Immunisation of mice against neosporosis International Journal for Parasitology 32 2002 867 876
15. H. Miyazaki, M. Imai, T. Hirayama, S. Saburi, M. Tanaka, M. Maruyama, C. Matsuo, H. Meguro, K. Nishibashi, F. Inoue, J. Djiane, A. Gertler, S. Tachi, K. Imakawa, and C. Tachi Establishment of feeder-independent cloned caprine trophoblast cell line which expresses placental lactogen and interferon tau Placenta 23 2002 613 630
16. H. Nakano, A. Shimada, K. Imai, T. Takezawa, T. Takahashi, and K. Hashizume Bovine trophoblastic cell differentiation on collagen substrata: formation of binucleate cells expressing placental lactogen Cell and Tissue Research 307 2002 225 235
17. Y. Nishikawa, N. Inoue, X. Xuan, H. Nagasawa, I. Igarashi, K. Fujisaki, H. Otsuka, and T. Mikami Protective efficacy of vaccination by recombinant vaccinia virus against Neospora caninum infection Vaccine 19 2001 1381 1390
18. Y. Nishikawa, X. Xuan, H. Nagasawa, I. Igarashi, K. Fujisaki, H. Otsuka, and T. Mikami Prevention of vertical transmission of Neospora caninum in BALB/c mice by recombinant vaccinia virus carrying NcSRS2 gene Vaccine 19 2001 1710 1716
19. Y. Nishikawa, X. Xuan, H. Nagasawa, I. Igarashi, K. Fujisaki, H. Otsuka, and T. Mikami Monoclonal antibody inhibition of Neospora caninum tachyzoite invasion into host cells International Journal for Parasitology 30 2000 51 58
20. A. Shimada, H. Nakano, T. Takahashi, K. Imai, and K. Hashizume Isolation and characterization of a bovine blastocyst-derived trophoblastic cell line, BT-1: development of a culture system in the absence of feeder cell Placenta 22 2001 652 662
21. T. Sulimenko, and P. Draber A fast and simple dot-immunobinding assay for quantification of mouse immunoglobulins in hybridoma culture supernatants Journal of Immunological Methods 289 2004 89 95
22. Y. Uchida, K. Ike, T. Kurotaki, A. Ito, and S. Imai Monoclonal antibodies preventing invasion of Neospora caninum tachyzoites into host cells Journal of Veterinary Medical Science 66 2004 1355 1358
23. Yokoyama, W.M., 1994. Production of monoclonal antibodies. In: Coligan, J.E. (Ed.), Current Protocols in Immunology. New York, Wiley Interscience: 2.2.1-2.5.17.