Products of anti-CD3/anti-CD28 activated lymphocytes induce differentiation and maturation of dendritic cells and have adjuvant-like activity in vitro and in vivo

Clinical Immunology

Volumn 129, Issue 1, 2008, Pages 58-68

  Harris, Kristina M ^a,d   Lenz, Petra ^c,d   Hankey, Kim G ^a,d   MacVittie, Thomas ^b,d   Farese, Ann ^b,d   Nakajima, Kaori ^c,d   Hasumi, Kenichiro ^c,d   Mann, Dean L ^a,d  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MARYLAND   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d Hasumi International Research Foundation   (Japan)

Author keywords

CD3 CD28; ; Conditioned medium; Dendritic cells; Differentiation; Maturation; ; T cell stimulation; ; Vaccine adjuvant

Indexed keywords

ALPHA INTERFERON; CD3 ANTIBODY; CHEMOKINE; CYTOKINE; MONOCLONAL ANTIBODY CD28;

ARTICLE; BIOLOGICAL ACTIVITY; CELL DIFFERENTIATION; CELL MATURATION; CELLULAR IMMUNITY; DENDRITIC CELL; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE CONDITIONED MEDIUM; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SUPERNATANT; T LYMPHOCYTE ACTIVATION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES; ANTIGENS, CD28; ANTIGENS, CD3; CELL DIFFERENTIATION; CULTURE MEDIA, CONDITIONED; CYTOKINES; DENDRITIC CELLS; HUMANS; LYMPHOCYTE ACTIVATION; MACACA MULATTA; MONOCYTES; OLIGODEOXYRIBONUCLEOTIDES; T-LYMPHOCYTES; VACCINES;

EID: 51249090937     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2008.06.003     Document Type: Article

References (44)

1. O'Doherty U., Peng M., Gezelter S., et al. Human blood contains two subsets of dendritic cells, one immunologically mature and the other immature. Immunology 82 (1994) 487-493
2. Robinson S.P., Patterson S., English N., Davies D., Knight S.C., and Reid C.D. Human peripheral blood contains two distinct lineages of dendritic cells. Eur. J. Immunol. 29 (1999) 2769-2778
3. Liu Y.J. Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity. Cell 106 (2001) 259-262
4. Steinman R.M. The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol. 9 (1991) 271-296
5. Banchereau J., and Steinman R.M. Dendritic cells and the control of immunity. Nature 392 (1998) 245-252
6. Banchereau J., Briere F., Caux C., et al. Immunobiology of dendritic cells. Annu. Rev. Immunol 18 (2000) 767-811
7. Inaba K., Metlay J.P., Crowley M.T., and Steinman R.M. Dendritic cells pulsed with protein antigens in vitro can prime antigen-specific, MHC-restricted T cells in situ. J. Exp. Med. 172 (1990) 631-640
8. Toujas L., Delcros J.G., Diez E., et al. Human monocyte-derived macrophages and dendritic cells are comparably effective in vitro in presenting HLA class I-restricted exogenous peptides. Immunology 91 (1997) 635-642
9. Weissman D., Ni H., Scales D., et al. HIV gag mRNA transfection of dendritic cells (DC) delivers encoded antigen to MHC class I and II molecules, causes DC maturation, and induces a potent human in vitro primary immune response. J. Immunol. 165 (2000) 4710-4717
10. Hart D.N., and McKenzie J.L. Interstitial dendritic cells. Int. Rev. Immunol. 6 (1990) 127-138
11. Liu Y.J., Kanzler H., Soumelis V., and Gilliet M. Dendritic cell lineage, plasticity and cross-regulation. Nat. Immunol. 2 (2001) 585-589
12. Gallucci S., Lolkema M., and Matzinger P. Natural adjuvants: endogenous activators of dendritic cells. Nat. Med. 5 (1999) 1249-1255
13. Guermonprez P., Valladeau J., Zitvogel L., Thery C., and Amigorena S. Antigen presentation and T cell stimulation by dendritic cells. Annu. Rev. Immunol. 20 (2002) 621-667
14. Bottomly K. T cells and dendritic cells get intimate. Science 283 (1999) 1124-1125
15. Reid S.D., Penna G., and Adorini L. The control of T cell responses by dendritic cell subsets. Curr. Opin. Immunol. 12 (2000) 114-121
16. Sallusto F., and Lanzavecchia A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J. Exp. Med. 179 (1994) 1109-1118
17. Kiertscher S.M., and Roth M.D. Human CD14+ leukocytes acquire the phenotype and function of antigen-presenting dendritic cells when cultured in GM-CSF and IL-4. J. Leukoc. Biol. 59 (1996) 208-218
18. Pickl W.F., Majdic O., Kohl P., et al. Molecular and functional characteristics of dendritic cells generated from highly purified CD14+ peripheral blood monocytes. J. Immunol. 157 (1996) 3850-3859
19. Zhou L.J., and Tedder T.F. CD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells. Proc. Natl. Acad. Sci. USA 93 (1996) 2588-2592
20. Reddy A., Sapp M., Feldman M., Subklewe M., and Bhardwaj N. A monocyte conditioned medium is more effective than defined cytokines in mediating the terminal maturation of human dendritic cells. Blood 90 (1997) 3640-3646
21. Jonuleit H., Kuhn U., Muller G., et al. Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions. Eur. J. Immunol. 27 (1997) 3135-3142
22. Steinbrink K., Paragnik L., Jonuleit H., Tuting T., Knop J., and Enk A.H. Induction of dendritic cell maturation and modulation of dendritic cell-induced immune responses by prostaglandins. Arch. Dermatol. Res. 292 (2000) 437-445
23. Mailliard R.B., Wankowicz-Kalinska A., Cai Q., et al. Alpha-type-1 polarized dendritic cells: a novel immunization tool with optimized CTL-inducing activity. Cancer Res. 64 (2004) 5934-5937
24. Zobywalski A., Javorovic M., Frankenberger B., et al. Generation of clinical grade dendritic cells with capacity to produce biologically active IL-12p70. J. Transl. Med. 5 (2007) 18
25. Ten Brinke A., Karsten M.L., Dieker M.C., Zwaginga J.J., and van Ham S.M. The clinical grade maturation cocktail monophosphoryl lipid A plus IFNgamma generates monocyte-derived dendritic cells with the capacity to migrate and induce Th1 polarization. Vaccine 25 (2007) 7145-7152
26. Cella M., Salio M., Sakakibara Y., Langen H., Julkunen I., and Lanzavecchia A. Maturation, activation, and protection of dendritic cells induced by double-stranded RNA. J. Exp. Med. 189 (1999) 821-829
27. Verdijk R.M., Mutis T., Esendam B., et al. Polyriboinosinic polyribocytidylic acid (poly(I:C)) induces stable maturation of functionally active human dendritic cells. J. Immunol. 163 (1999) 57-61
28. Dauer M., Obermaier B., Herten J., et al. Mature dendritic cells derived from human monocytes within 48 hours: a novel strategy for dendritic cell differentiation from blood precursors. J. Immunol. 170 (2003) 4069-4076
29. O'Doherty U., Steinman R.M., Peng M., et al. Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium. J. Exp. Med. 178 (1993) 1067-1076
30. Baxevanis C.N., Tsiatas M.L., Cacoullos N.T., et al. Induction of anti-tumour lymphocytes in cancer patients after brief exposure to supernatants from cultures of anti-CD3-stimulated allogeneic lymphocytes. Br. J. Cancer 76 (1997) 1072-1080
31. Tsiatas M.L., Gritzapis A.D., Cacoullos N.T., Papadhimitriou S.I., Baxevanis C.N., and Papamichail M. A novel culture environment for generating mature human dentritic cells from peripheral blood CD14+ cells. Anticancer. Res. 21 (2001) 1199-1206
32. Kato K., Takaue Y., and Wakasugi H. T-cell-conditioned medium efficiently induces the maturation and function of human dendritic cells. J. Leukoc. Biol. 70 (2001) 941-949
33. Krug A., Rothenfusser S., Selinger S., et al. CpG-A oligonucleotides induce a monocyte-derived dendritic cell-like phenotype that preferentially activates CD8 T cells. J. Immunol. 170 (2003) 3468-3477
34. Jego G., Palucka A.K., Blanck J.P., Chalouni C., Pascual V., and Banchereau J. Plasmacytoid dendritic cells induce plasma cell differentiation through type I interferon and interleukin 6. Immunity 19 (2003) 225-234
35. Grouard G., Rissoan M.C., Filgueira L., Durand I., Banchereau J., and Liu Y.J. The enigmatic plasmacytoid T cells develop into dendritic cells with interleukin (IL)-3 and CD40-ligand. J. Exp. Med. 185 (1997) 1101-1111
36. Rothenfusser S., Tuma E., Endres S., and Hartmann G. Plasmacytoid dendritic cells: the key to CpG. Hum. Immunol. 63 (2002) 1111-1119
37. Hartmann G., Weiner G.J., and Krieg A.M. CpG DNA: a potent signal for growth, activation, and maturation of human dendritic cells. Proc. Natl. Acad. Sci. USA 96 (1999) 9305-9310
38. Kadowaki N., and Liu Y.J. Natural type I interferon-producing cells as a link between innate and adaptive immunity. Hum. Immunol. 63 (2002) 1126-1132
39. Gary-Gouy H., Lebon P., and Dalloul A.H. Type I interferon production by plasmacytoid dendritic cells and monocytes is triggered by viruses, but the level of production is controlled by distinct cytokines. J. Interferon. Cytokine Res. 22 (2002) 653-659
40. Appay V., and Rowland-Jones S.L. RANTES: a versatile and controversial chemokine. Trends Immunol. 22 (2001) 83-87
41. O'Garra A. Cytokines induce the development of functionally heterogeneous T helper cell subsets. Immunity 8 (1998) 275-283
42. Zou G.M., and Tam Y.K. Cytokines in the generation and maturation of dendritic cells: recent advances. Eur. Cytokine Netw. 13 (2002) 186-199
43. Chomarat P., Dantin C., Bennett L., Banchereau J., and Palucka A.K. TNF skews monocyte differentiation from macrophages to dendritic cells. J. Immunol. 171 (2003) 2262-2269
44. Luft T., Jefford M., Luetjens P., et al. Functionally distinct dendritic cell (DC) populations induced by physiologic stimuli: prostaglandin E(2) regulates the migratory capacity of specific DC subsets. Blood 100 (2002) 1362-1372