메뉴 건너뛰기




Volumn 60, Issue 8, 2008, Pages 923-929

Parkin and mitochondria

Author keywords

Function; Mitochondria; Pakinson disease; PARK; Parkin

Indexed keywords

DJ 1 PROTEIN; PARKIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEASOME; UBIQUITIN;

EID: 51149106952     PISSN: 18816096     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (8)

References (43)
  • 1
    • 33644543761 scopus 로고    scopus 로고
    • Expanding insights of mitochondrial dysfunction in Parkinson's disease
    • Abou-Sleiman PM, Muqit MM, Wood NW: Expanding insights of mitochondrial dysfunction in Parkinson's disease. Nat Rev Neurosci 7: 207-219, 2006
    • (2006) Nat Rev Neurosci , vol.7 , pp. 207-219
    • Abou-Sleiman, P.M.1    Muqit, M.M.2    Wood, N.W.3
  • 2
    • 33750370804 scopus 로고    scopus 로고
    • Understanding the molecular causes of Parkinson's disease
    • Wood-Kaczmar A, Gandhi S, Wood NW: Understanding the molecular causes of Parkinson's disease. Trends Mol Med 12: 521-528, 2006
    • (2006) Trends Mol Med , vol.12 , pp. 521-528
    • Wood-Kaczmar, A.1    Gandhi, S.2    Wood, N.W.3
  • 3
    • 0033681149 scopus 로고    scopus 로고
    • Chronic systemic pesticide exposure reproduces features of Parkinson's disease
    • Betarbet R, Sherer TB, MacKenzie G, Garcia-Osuna M, Panov AV, et al: Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat Neurosci 3: 1301-1306, 2000
    • (2000) Nat Neurosci , vol.3 , pp. 1301-1306
    • Betarbet, R.1    Sherer, T.B.2    MacKenzie, G.3    Garcia-Osuna, M.4    Panov, A.V.5
  • 4
    • 0032499264 scopus 로고    scopus 로고
    • Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
    • Kitada T, Asakawa S, Hattori N, Matsumine H, Yamamura Y, et al: Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392: 605-608, 1998
    • (1998) Nature , vol.392 , pp. 605-608
    • Kitada, T.1    Asakawa, S.2    Hattori, N.3    Matsumine, H.4    Yamamura, Y.5
  • 5
    • 0342368772 scopus 로고    scopus 로고
    • Association between early-onset Parkinson's disease and mutations in the parkin gene
    • Lücking CB, Dürr A, Bonifati V, Vaughan J, De Michele G, et al: Association between early-onset Parkinson's disease and mutations in the parkin gene. N Engl J Med 342: 1560-7, 2000
    • (2000) N Engl J Med , vol.342 , pp. 1560-1567
    • Lücking, C.B.1    Dürr, A.2    Bonifati, V.3    Vaughan, J.4    De Michele, G.5
  • 6
    • 0033933048 scopus 로고    scopus 로고
    • Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
    • Shimura H, Hattori N, Kubo S, Mizuno Y, Asakawa S, et al: Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nat Genet 25: 302-305, 2000
    • (2000) Nat Genet , vol.25 , pp. 302-305
    • Shimura, H.1    Hattori, N.2    Kubo, S.3    Mizuno, Y.4    Asakawa, S.5
  • 7
    • 1842455356 scopus 로고    scopus 로고
    • Parkin genetics: One model for Parkinson's disease
    • Mata IF, Lockhart PJ, Farrer MJ: Parkin genetics: one model for Parkinson's disease. Hum Mol Genet 13 (Spec No 1): R127-133, 2004
    • (2004) Hum Mol Genet , vol.13 , Issue.SPEC 1
    • Mata, I.F.1    Lockhart, P.J.2    Farrer, M.J.3
  • 8
    • 0037368598 scopus 로고    scopus 로고
    • Parkin binds the Rpn10 subunit of 26S proteasomes through its ubiquitin-like domain
    • Sakata E, Yamaguchi Y, Kurimoto E, Kikuchi J, Yokoyama S, et al: Parkin binds the Rpn10 subunit of 26S proteasomes through its ubiquitin-like domain. EMBO Rep 4: 301-306, 2003
    • (2003) EMBO Rep , vol.4 , pp. 301-306
    • Sakata, E.1    Yamaguchi, Y.2    Kurimoto, E.3    Kikuchi, J.4    Yokoyama, S.5
  • 9
    • 0034266806 scopus 로고    scopus 로고
    • RING finger proteins: Mediators of ubiquitin ligase activity
    • Joazeiro, CAP, Weissman AM: RING finger proteins: mediators of ubiquitin ligase activity. Cell 102: 549-552, 2000
    • (2000) Cell , vol.102 , pp. 549-552
    • Joazeiro, C.A.P.1    Weissman, A.M.2
  • 10
    • 0034614506 scopus 로고    scopus 로고
    • Coregulator small nuclear RING finger protein (SNURF) enhances Sp1- and steroid receptor-mediated transcription by different mechanisms
    • Poukka H, Aarnisalo P, Santti H, Jänne OA, Palvimo JJ: Coregulator small nuclear RING finger protein (SNURF) enhances Sp1- and steroid receptor-mediated transcription by different mechanisms. J Biol Chem 275: 571-579, 2000
    • (2000) J Biol Chem , vol.275 , pp. 571-579
    • Poukka, H.1    Aarnisalo, P.2    Santti, H.3    Jänne, O.A.4    Palvimo, J.J.5
  • 11
    • 33644778845 scopus 로고    scopus 로고
    • Parkin enhances mitochondrial biogenesis in proliferating cells
    • Kuroda Y, Mitsui T, Kunishige M, Shono M, Akaike M, et al: Parkin enhances mitochondrial biogenesis in proliferating cells. Hum Mol Genet 15: 883-895, 2006
    • (2006) Hum Mol Genet , vol.15 , pp. 883-895
    • Kuroda, Y.1    Mitsui, T.2    Kunishige, M.3    Shono, M.4    Akaike, M.5
  • 12
    • 0035795205 scopus 로고    scopus 로고
    • Parkin immunoreactivity in the brain of human and non-human primates: An immunohistochemical analysis in normal conditions and in parkinsonian syndromes
    • Zarate-Lagunes M, Gu WJ, Blanchard V, Francois C, Muriel MP, et al: Parkin immunoreactivity in the brain of human and non-human primates: an immunohistochemical analysis in normal conditions and in parkinsonian syndromes. J Comp Neurol 432: 184-196, 2001
    • (2001) J Comp Neurol , vol.432 , pp. 184-196
    • Zarate-Lagunes, M.1    Gu, W.J.2    Blanchard, V.3    Francois, C.4    Muriel, M.P.5
  • 14
    • 0032957883 scopus 로고    scopus 로고
    • Immunohistochemical and subcellular localization of parkin protein: Absence of protein in autosomal recessive juvenile parkinsonism patient
    • Shimura H, Hattori N, Kubo S, Yoshikawa M, Kitada T, et al: Immunohistochemical and subcellular localization of parkin protein: absence of protein in autosomal recessive juvenile parkinsonism patient. Ann Neurol 45: 668-672, 1999
    • (1999) Ann Neurol , vol.45 , pp. 668-672
    • Shimura, H.1    Hattori, N.2    Kubo, S.3    Yoshikawa, M.4    Kitada, T.5
  • 16
    • 0037338634 scopus 로고    scopus 로고
    • Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death
    • Darios F, Corti O, Lucking CB, Hampe C, Muriel MP, et al: Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death. Hum Mol Genet 12: 517-526, 2003
    • (2003) Hum Mol Genet , vol.12 , pp. 517-526
    • Darios, F.1    Corti, O.2    Lucking, C.B.3    Hampe, C.4    Muriel, M.P.5
  • 17
    • 33747179913 scopus 로고    scopus 로고
    • Parkin affects mitochondrial function and apoptosis in neuronal and myogenic cells
    • Kuroda Y, Mitsui T, Kunishige M, Matsumoto T: Parkin affects mitochondrial function and apoptosis in neuronal and myogenic cells. Biochem Biophys Res Commun 348: 787-793, 2006
    • (2006) Biochem Biophys Res Commun , vol.348 , pp. 787-793
    • Kuroda, Y.1    Mitsui, T.2    Kunishige, M.3    Matsumoto, T.4
  • 18
    • 2442481789 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative damage in parkin-deficient mice
    • Palacino JJ, Sagi D, Goldberg MS, Krauss S, Motz C, et al: Mitochondrial dysfunction and oxidative damage in parkin-deficient mice. J Biol Chem 279: 18614-18622, 2004
    • (2004) J Biol Chem , vol.279 , pp. 18614-18622
    • Palacino, J.J.1    Sagi, D.2    Goldberg, M.S.3    Krauss, S.4    Motz, C.5
  • 19
    • 33744963796 scopus 로고    scopus 로고
    • Parkin protects against mitochondrial toxins and beta-amyloid accumulation in skeletal muscle cells
    • Rosen KM, Veereshwarayya V, Moussa CE, Fu Q, Goldberg MS, et al: Parkin protects against mitochondrial toxins and beta-amyloid accumulation in skeletal muscle cells. J Biol Chem 281: 12809-12816, 2006
    • (2006) J Biol Chem , vol.281 , pp. 12809-12816
    • Rosen, K.M.1    Veereshwarayya, V.2    Moussa, C.E.3    Fu, Q.4    Goldberg, M.S.5
  • 20
    • 0141891953 scopus 로고    scopus 로고
    • Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons
    • Goldberg MS, Fleming SM, Palacino JJ, Cepeda C, Lam HA, et al: Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons. J Biol Chem 278: 43628-34365, 2003
    • (2003) J Biol Chem , vol.278 , pp. 43628-34365
    • Goldberg, M.S.1    Fleming, S.M.2    Palacino, J.J.3    Cepeda, C.4    Lam, H.A.5
  • 21
    • 13844313915 scopus 로고    scopus 로고
    • Parkin-deficient mice are not a robust model of parkinsonism
    • Perez FA, Palmiter RD: Parkin-deficient mice are not a robust model of parkinsonism. Proc Natl Acad Sci U S A 102: 2174-2179, 2005
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 2174-2179
    • Perez, F.A.1    Palmiter, R.D.2
  • 23
    • 33846898753 scopus 로고    scopus 로고
    • The Drosophila parkin homologue is required for normal mitochondrial dynamics during spermiogenesis
    • Riparbelli MG, Callaini G: The Drosophila parkin homologue is required for normal mitochondrial dynamics during spermiogenesis. Dev Biol 303: 108-120, 2007
    • (2007) Dev Biol , vol.303 , pp. 108-120
    • Riparbelli, M.G.1    Callaini, G.2
  • 24
    • 0037386532 scopus 로고    scopus 로고
    • Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants
    • Greene JC, Whitworth AJ, Kuo I, Andrews LA, Feany MB, et al: Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants. Proc Natl Acad Sci U S A 100: 4078-4083, 2003
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 4078-4083
    • Greene, J.C.1    Whitworth, A.J.2    Kuo, I.3    Andrews, L.A.4    Feany, M.B.5
  • 25
    • 15544380902 scopus 로고    scopus 로고
    • Genetic and genomic studies of Drosophila parkin mutants implicate oxidative stress and innate immune responses in pathogenesis
    • Greene JC, Whitworth AJ, Andrews LA, Parker TJ, Pallanck LJ: Genetic and genomic studies of Drosophila parkin mutants implicate oxidative stress and innate immune responses in pathogenesis. Hum Mol Genet 14: 799-811, 2005
    • (2005) Hum Mol Genet , vol.14 , pp. 799-811
    • Greene, J.C.1    Whitworth, A.J.2    Andrews, L.A.3    Parker, T.J.4    Pallanck, L.J.5
  • 26
  • 27
    • 27944444154 scopus 로고    scopus 로고
    • Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism
    • Silvestri L, Caputo V, Bellacchio E, Atorino L, Dallapiccola B, et al: Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism. Hum Mol Genet 14: 3477-3492, 2005
    • (2005) Hum Mol Genet , vol.14 , pp. 3477-3492
    • Silvestri, L.1    Caputo, V.2    Bellacchio, E.3    Atorino, L.4    Dallapiccola, B.5
  • 28
    • 33750220194 scopus 로고    scopus 로고
    • C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1
    • Sim CH, Lio DS, Mok SS, Masters CL, Hill AF, et al: C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1. Hum Mol Genet 15: 3251-3262, 2006
    • (2006) Hum Mol Genet , vol.15 , pp. 3251-3262
    • Sim, C.H.1    Lio, D.S.2    Mok, S.S.3    Masters, C.L.4    Hill, A.F.5
  • 29
    • 33746080412 scopus 로고    scopus 로고
    • Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin
    • Yang Y, Gehrke S, Imai Y, Huang Z, Ouyang Y, et al: Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin. Proc Natl Acad Sci U S A 103: 10793-10798, 2006
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 10793-10798
    • Yang, Y.1    Gehrke, S.2    Imai, Y.3    Huang, Z.4    Ouyang, Y.5
  • 30
    • 33745589773 scopus 로고    scopus 로고
    • Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
    • Clark IE, Dodson MW, Jiang C, Cao JH, Huh JR, et al: Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature 441: 1162-1166, 2006
    • (2006) Nature , vol.441 , pp. 1162-1166
    • Clark, I.E.1    Dodson, M.W.2    Jiang, C.3    Cao, J.H.4    Huh, J.R.5
  • 31
    • 33745602748 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
    • Park J, Lee SB, Lee S, Kim Y, Song S, et al: Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature 441: 1157-1161, 2006
    • (2006) Nature , vol.441 , pp. 1157-1161
    • Park, J.1    Lee, S.B.2    Lee, S.3    Kim, Y.4    Song, S.5
  • 32
    • 33751267701 scopus 로고    scopus 로고
    • Parkin: A multifaceted ubiquitin ligase
    • Moore DJ: Parkin: a multifaceted ubiquitin ligase. Biochem Soc Trans 34(Pt 5): 749-753, 2006
    • (2006) Biochem Soc Trans , vol.34 , Issue.PART 5 , pp. 749-753
    • Moore, D.J.1
  • 33
    • 24944534660 scopus 로고    scopus 로고
    • Mitochondrial localization of the Parkinson's disease related protein DJ-1: Implications for pathogenesis
    • Zhang L, Shimoji M, Thomas B, Moore DJ, Yu SW, et al: Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis. Hum Mol Genet 14: 2063-2073, 2005
    • (2005) Hum Mol Genet , vol.14 , pp. 2063-2073
    • Zhang, L.1    Shimoji, M.2    Thomas, B.3    Moore, D.J.4    Yu, S.W.5
  • 34
    • 20944437573 scopus 로고    scopus 로고
    • The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis
    • Xu J, Zhong N, Wang H, Elias JE, Kim CY, et al: The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis. Hum Mol Genet. 14: 1231-1241, 2005
    • (2005) Hum Mol Genet , vol.14 , pp. 1231-1241
    • Xu, J.1    Zhong, N.2    Wang, H.3    Elias, J.E.4    Kim, C.Y.5
  • 35
    • 33750052885 scopus 로고    scopus 로고
    • DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2
    • Clements CM, McNally RS, Conti BJ, Mak TW, Ting JP: DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2. Proc Natl Acad Sci U S A 103: 15091-15096, 2006
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 15091-15096
    • Clements, C.M.1    McNally, R.S.2    Conti, B.J.3    Mak, T.W.4    Ting, J.P.5
  • 36
    • 12344251678 scopus 로고    scopus 로고
    • Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress
    • Moore DJ, Zhang L, Troncoso J, Lee MK, Hattori N, et al: Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress. Hum Mol Genet 14: 71-84, 2005
    • (2005) Hum Mol Genet , vol.14 , pp. 71-84
    • Moore, D.J.1    Zhang, L.2    Troncoso, J.3    Lee, M.K.4    Hattori, N.5
  • 37
    • 33744760852 scopus 로고    scopus 로고
    • Association of PINK1 and DJ-1 confers digenic inheritance of early-onset Parkinson's disease
    • Tang B, Xiong H, Sun P, Zhang Y, Wang D, et al: Association of PINK1 and DJ-1 confers digenic inheritance of early-onset Parkinson's disease. Hum Mol Genet 15: 1816-1825, 2006
    • (2006) Hum Mol Genet , vol.15 , pp. 1816-1825
    • Tang, B.1    Xiong, H.2    Sun, P.3    Zhang, Y.4    Wang, D.5
  • 38
    • 37049004489 scopus 로고    scopus 로고
    • Mitochondria in the aetiology and pathogenesis of Parkinson's disease
    • Schapira AH: Mitochondria in the aetiology and pathogenesis of Parkinson's disease. Lancet Neurol 7: 97-109, 2008
    • (2008) Lancet Neurol , vol.7 , pp. 97-109
    • Schapira, A.H.1
  • 39
    • 34249937901 scopus 로고    scopus 로고
    • Pink1, Parkin, DJ-1 and mitochondrial dysfunction in Parkinson's disease
    • Dodson MW, Guo M: Pink1, Parkin, DJ-1 and mitochondrial dysfunction in Parkinson's disease. Curr Opin Neurobiol 17: 331-337, 2007
    • (2007) Curr Opin Neurobiol , vol.17 , pp. 331-337
    • Dodson, M.W.1    Guo, M.2
  • 40
    • 29444437871 scopus 로고    scopus 로고
    • Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration
    • Smith WW, Pei Z, Jiang H, Moore DJ, Liang Y, et al: Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration. Proc Natl Acad Sci U S A 102: 18676-18681, 2005
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 18676-18681
    • Smith, W.W.1    Pei, Z.2    Jiang, H.3    Moore, D.J.4    Liang, Y.5
  • 41
    • 33747477123 scopus 로고    scopus 로고
    • Parkin and its association with alpha-synuclein and AbetaPP in inclusion-body myositis and AbetaPP-overexpressing cultured human muscle fibers
    • Paciello O, Wójcik S, Engel WK, McFerrin J, Askanas V: Parkin and its association with alpha-synuclein and AbetaPP in inclusion-body myositis and AbetaPP-overexpressing cultured human muscle fibers. Acta Myol 25: 13-22, 2006
    • (2006) Acta Myol , vol.25 , pp. 13-22
    • Paciello, O.1    Wójcik, S.2    Engel, W.K.3    McFerrin, J.4    Askanas, V.5
  • 42
    • 10644281090 scopus 로고    scopus 로고
    • Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an alpha-synuclein rat model of Parkinson's disease
    • Lo Bianco C, Schneider BL, Bauer M, Sajadi A, Brice A, et al: Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an alpha-synuclein rat model of Parkinson's disease. Proc Natl Acad Sci U S A 101: 17510-17515, 2004
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 17510-17515
    • Lo Bianco, C.1    Schneider, B.L.2    Bauer, M.3    Sajadi, A.4    Brice, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.