Inhibition of stearoyl CoA desaturase activity induces hypercholesterolemia in the cholesterol-fed hamster

Journal of Lipid Research

Volumn 49, Issue 7, 2008, Pages 1456-1465

  Major, Catherine A ^a   Ryan, Kevin ^a   Bennett, Andrew J ^a   Lock, Adam L ^b,c   Bauman, Dale E ^b   Salter, Andrew M ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b Department of Obstetrics Gynecology   (United States)

^c UNIVERSITY OF VERMONT   (United States)

Author keywords

Gene expression; Hamsters; Lipoproteins; Sterculic oil

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ACYL COENZYME A DESATURASE; ALANINE AMINOTRANSFERASE; CHOLESTEROL; FATTY ACID SYNTHASE; LIPOPROTEIN; LIPOPROTEIN LIPASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; STERCULIC OIL; STEROL REGULATORY ELEMENT BINDING PROTEIN 1A; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; UNCLASSIFIED DRUG; FATTY ACID;

ADIPOSE TISSUE; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL ESTERIFICATION; CHOLESTEROL INTAKE; CONTROLLED STUDY; ENZYME INHIBITION; HYPERCHOLESTEROLEMIA; LIPID DIET; LIPID STORAGE; LIPOPROTEIN BLOOD LEVEL; LIVER INJURY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; SYRIAN HAMSTER; WEIGHT REDUCTION; ANIMAL; ANIMAL FOOD; BLOOD; BODY WEIGHT; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; HAMSTER; LIVER; METABOLISM; ORGAN SIZE;

ALANINE TRANSAMINASE; ANIMAL FEED; ANIMALS; BODY WEIGHT; CHOLESTEROL; CRICETINAE; FATTY ACIDS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HYPERCHOLESTEROLEMIA; LIPOPROTEINS; LIVER; ORGAN SIZE; RNA, MESSENGER; STEAROYL-COA DESATURASE;

EID: 50949098867     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M700596-JLR200     Document Type: Article

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