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Volumn 97, Issue 4, 2007, Pages 464-471

Gemcitabine with a specific conformal 3D 5FU radiochemotherapy technique is safe and effective in the definitive management of locally advanced pancreatic cancer

Author keywords

Conformal radiation; Gemcitabine; Locally advanced; Pancreas cancer

Indexed keywords

FLUOROURACIL; GEMCITABINE;

EID: 34547907771     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6603900     Document Type: Article
Times cited : (38)

References (35)
  • 1
    • 0036682041 scopus 로고    scopus 로고
    • Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma: Eastern Cooperative Oncology Group Trial E2297
    • Berlin JD, Catalano P, Thomas JP, Jugler JW, Haller DG, Bowen Benson III A (2002) Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma: Eastern Cooperative Oncology Group Trial E2297. J Clin Oncol 20: 3270-3275
    • (2002) J Clin Oncol , vol.20 , pp. 3270-3275
    • Berlin, J.D.1    Catalano, P.2    Thomas, J.P.3    Jugler, J.W.4    Haller, D.G.5    Bowen Benson III, A.6
  • 2
    • 4644239753 scopus 로고    scopus 로고
    • Cancer and leukaemia group B (CALGB) 89805: Phase II chemoradiation trial using gemcitabine in patients with locoregional adenocarcinoma of the pancreas
    • Blackstock AW, Tepper JE, Niedwiecki D, Hollis DR, Mayer RJ, Tempero MA (2003) Cancer and leukaemia group B (CALGB) 89805: phase II chemoradiation trial using gemcitabine in patients with locoregional adenocarcinoma of the pancreas. Int J Gastrointest Cancer 34: 107-116
    • (2003) Int J Gastrointest Cancer , vol.34 , pp. 107-116
    • Blackstock, A.W.1    Tepper, J.E.2    Niedwiecki, D.3    Hollis, D.R.4    Mayer, R.J.5    Tempero, M.A.6
  • 5
    • 34547884343 scopus 로고    scopus 로고
    • Chauffert B, Mornex F, Bonnetain F, Triboulet JP, Bouche O, Rougier P, Bosset JF, Aparicio T, Masskouri F, Bedenne L (2006) Phase III trial comparing initial chemoradiotherapy (intermittent cisplatin and infusional 5-FU) followed by gemcitabine vs. gemcitabine alone in patients with locally advanced non metastatic pancreatic cancer: a FFCD-SFRO study. J Clin Oncol 24(18S): 4008; (abstract)
    • Chauffert B, Mornex F, Bonnetain F, Triboulet JP, Bouche O, Rougier P, Bosset JF, Aparicio T, Masskouri F, Bedenne L (2006) Phase III trial comparing initial chemoradiotherapy (intermittent cisplatin and infusional 5-FU) followed by gemcitabine vs. gemcitabine alone in patients with locally advanced non metastatic pancreatic cancer: a FFCD-SFRO study. J Clin Oncol 24(18S): 4008; (abstract)
  • 6
    • 0037083621 scopus 로고    scopus 로고
    • Gemcitabine alone or with cisplatin for the treatment of patients with locally advanced and/or metastatic pancreatic carcinoma: A prospective, randomized phase III study of the Gruppo Oncologico dell'Italia Meridonale
    • Colucci G, Giuliani F, Gebbia V, Biglietto M, Rabitti P, Uomo G, Cigolari S, Testa A, Maiello E, Lopez M (2002) Gemcitabine alone or with cisplatin for the treatment of patients with locally advanced and/or metastatic pancreatic carcinoma: a prospective, randomized phase III study of the Gruppo Oncologico dell'Italia Meridonale. Cancer 94: 902-910
    • (2002) Cancer , vol.94 , pp. 902-910
    • Colucci, G.1    Giuliani, F.2    Gebbia, V.3    Biglietto, M.4    Rabitti, P.5    Uomo, G.6    Cigolari, S.7    Testa, A.8    Maiello, E.9    Lopez, M.10
  • 7
    • 29344476191 scopus 로고    scopus 로고
    • Phase III randomised comparison of gemcitabine (GEM) versus gemcitabine plus capecitabine (GEM-CAP) in patients with advanced pancreatic cancer
    • abstract PS11
    • Cunningham D, Chau I, Stocken D, Davies C, Dunn J, Valle J, Smith D, Steward W, Harper P, Neoptolemos J (2005) Phase III randomised comparison of gemcitabine (GEM) versus gemcitabine plus capecitabine (GEM-CAP) in patients with advanced pancreatic cancer. Eur J Cancer Suppl 3: 12; (abstract PS11)
    • (2005) Eur J Cancer Suppl , vol.3 , pp. 12
    • Cunningham, D.1    Chau, I.2    Stocken, D.3    Davies, C.4    Dunn, J.5    Valle, J.6    Smith, D.7    Steward, W.8    Harper, P.9    Neoptolemos, J.10
  • 8
    • 25444453200 scopus 로고    scopus 로고
    • Radiochemotherapy in the management of pancreatic cancer-Part II: Use in adjuvant and locally unresectable settings
    • Dickler A, Abrams RA (2005) Radiochemotherapy in the management of pancreatic cancer-Part II: use in adjuvant and locally unresectable settings. Semin Rad Oncol 15: 235-244
    • (2005) Semin Rad Oncol , vol.15 , pp. 235-244
    • Dickler, A.1    Abrams, R.A.2
  • 11
    • 0022225610 scopus 로고
    • Radiation therapy combined with adriamycin or 5-fluorouracil for the treatment of locally unresectable pancreatic carcinoma
    • Gastrointestinal Tumor Study Group
    • Gastrointestinal Tumor Study Group (1985) Radiation therapy combined with adriamycin or 5-fluorouracil for the treatment of locally unresectable pancreatic carcinoma. Cancer 56: 2563-2568
    • (1985) Cancer , vol.56 , pp. 2563-2568
  • 14
    • 0003651542 scopus 로고
    • ICRU , Bethesda, MD: International Commission on Radiation Units and Measurements
    • ICRU (1993) Report No. 50, Prescribing, Recording, and Reporting Photon Beam Therapy. Bethesda, MD: International Commission on Radiation Units and Measurements
    • (1993) Prescribing, Recording, and Reporting Photon Beam Therapy
  • 16
    • 19444387950 scopus 로고    scopus 로고
    • Docetaxel in the management of advanced pancreatic cancer
    • Lopes G, Rocha Lima CM (2005) Docetaxel in the management of advanced pancreatic cancer. Semin Oncol 32(Suppl 4): S10-S23
    • (2005) Semin Oncol , vol.32 , Issue.SUPPL. 4
    • Lopes, G.1    Rocha Lima, C.M.2
  • 18
    • 0037099604 scopus 로고    scopus 로고
    • Multicenter randomized phase III trial comparing protracted venous infusion (PVI) fluorouracil (5-FU) with PVI 5-FU plus mitomycin in inoperable pancreatic cancer
    • Maisey N, Chau I, Cunningham D, Norman A, Seymour M, Hickish T, Iveson T, O'Brien M, Tebbutt N, Harrington A, Hill M (2002) Multicenter randomized phase III trial comparing protracted venous infusion (PVI) fluorouracil (5-FU) with PVI 5-FU plus mitomycin in inoperable pancreatic cancer. J Clin Oncol 20: 3130-3136
    • (2002) J Clin Oncol , vol.20 , pp. 3130-3136
    • Maisey, N.1    Chau, I.2    Cunningham, D.3    Norman, A.4    Seymour, M.5    Hickish, T.6    Iveson, T.7    O'Brien, M.8    Tebbutt, N.9    Harrington, A.10    Hill, M.11
  • 19
    • 27144435114 scopus 로고    scopus 로고
    • CA19-9 as a prognostic factor in inoperable pancreatic cancer: The implication for clinical trials
    • Maisey NR, Norman AR, Hill A, Massey A, Oates J, Cunningham D (2005) CA19-9 as a prognostic factor in inoperable pancreatic cancer: the implication for clinical trials. Br J Cancer 93: 740-743
    • (2005) Br J Cancer , vol.93 , pp. 740-743
    • Maisey, N.R.1    Norman, A.R.2    Hill, A.3    Massey, A.4    Oates, J.5    Cunningham, D.6
  • 20
    • 0141688333 scopus 로고    scopus 로고
    • Comparison of gemcitabine versus the matrix metalloproteinase inhibitor BAY 12-9566 in patients with advanced or metastatic adenocarcinoma of the pancreas: A phase III trial of the National Cancer Institute of Canada Clinical Trials Group
    • Moore MJ, Hamm J, Dancey J, Eisenberg PD, Dagenais M, Fields A, Hagan K, Greenberg B, Colwell B, Zee B, Tu D, Ottaway J, Humphrey R, Seymour L (2003) Comparison of gemcitabine versus the matrix metalloproteinase inhibitor BAY 12-9566 in patients with advanced or metastatic adenocarcinoma of the pancreas: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 21: 3296-3302
    • (2003) J Clin Oncol , vol.21 , pp. 3296-3302
    • Moore, M.J.1    Hamm, J.2    Dancey, J.3    Eisenberg, P.D.4    Dagenais, M.5    Fields, A.6    Hagan, K.7    Greenberg, B.8    Colwell, B.9    Zee, B.10    Tu, D.11    Ottaway, J.12    Humphrey, R.13    Seymour, L.14
  • 21
    • 34547856289 scopus 로고    scopus 로고
    • Moureau-Zabotto L, Phélip J, Afchain P, Mineur L, André T, Vendrely V, Lledo G, Dupuis O, Touboul E, Balosso J (2006) Concomitant administration of weekly oxaliplatin, 5FU continuous infusion and radiotherapy in locally advanced pancreatic cancer (LAPC): a GERCOR phase II study. J Clin Oncol 24(18S): 4039
    • Moureau-Zabotto L, Phélip J, Afchain P, Mineur L, André T, Vendrely V, Lledo G, Dupuis O, Touboul E, Balosso J (2006) Concomitant administration of weekly oxaliplatin, 5FU continuous infusion and radiotherapy in locally advanced pancreatic cancer (LAPC): a GERCOR phase II study. J Clin Oncol 24(18S): 4039
  • 23
    • 33748675916 scopus 로고    scopus 로고
    • Comparison of noncoplanar and coplanar irradiation techniques to treat cancer of the pancreas
    • Osborne C, Bydder SA, Ebert MA, Spry NA (2006) Comparison of noncoplanar and coplanar irradiation techniques to treat cancer of the pancreas. Austral Radiol 50: 463-467
    • (2006) Austral Radiol , vol.50 , pp. 463-467
    • Osborne, C.1    Bydder, S.A.2    Ebert, M.A.3    Spry, N.A.4
  • 25
    • 0043202995 scopus 로고    scopus 로고
    • A phase II study of mitomycin C, cisplatin and protracted infusional 5-fluorouracil in advanced pancreatic carcinoma: Efficacy and low toxicity
    • Petty RD, Nicolson MC, Skaria S, Sinclair TS, Samuel LM, Koruth M (2003) A phase II study of mitomycin C, cisplatin and protracted infusional 5-fluorouracil in advanced pancreatic carcinoma: efficacy and low toxicity. Ann Oncol 14: 1100-1105
    • (2003) Ann Oncol , vol.14 , pp. 1100-1105
    • Petty, R.D.1    Nicolson, M.C.2    Skaria, S.3    Sinclair, T.S.4    Samuel, L.M.5    Koruth, M.6
  • 26
    • 34547895529 scopus 로고    scopus 로고
    • Poplin E, Levy DE, Berlin J, Rothenberg M, Cella D, Mitchell E, Alberts S, Benson III A (2006a) Phase III trial of gemcitabine (30-min infusion) versus gemcitabine (fixed-dose-rate infusion [FDR]) versus gemcitabine + oxaliplatin (GEMOX) in patients with advanced pancreatic cancer (E6201). J Clin Oncol 24(18S): LBA4004; (abstract)
    • Poplin E, Levy DE, Berlin J, Rothenberg M, Cella D, Mitchell E, Alberts S, Benson III A (2006a) Phase III trial of gemcitabine (30-min infusion) versus gemcitabine (fixed-dose-rate infusion [FDR]) versus gemcitabine + oxaliplatin (GEMOX) in patients with advanced pancreatic cancer (E6201). J Clin Oncol 24(18S): LBA4004; (abstract)
  • 30
    • 4644327989 scopus 로고    scopus 로고
    • Irinotecan plus gemcitabine results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate
    • Rocha Lima CM, Green MR, Rotche R, Miller Jr WH, Jeffrey GM, Cisar LA, Morganti A, Orlando N, Gruia G, Miller LL (2004) Irinotecan plus gemcitabine results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate. J Clin Oncol 22: 3776-3783
    • (2004) J Clin Oncol , vol.22 , pp. 3776-3783
    • Rocha Lima, C.M.1    Green, M.R.2    Rotche, R.3    Miller Jr, W.H.4    Jeffrey, G.M.5    Cisar, L.A.6    Morganti, A.7    Orlando, N.8    Gruia, G.9    Miller, L.L.10
  • 33
    • 33746129951 scopus 로고    scopus 로고
    • Chemoradiotherapy with gemcitabine and continuous 5-FU in patients with primary inoperable pancreatic cancer
    • Wilkowski R, Thoma M, Bruns C, Wagner A, Heinemann V (2006) Chemoradiotherapy with gemcitabine and continuous 5-FU in patients with primary inoperable pancreatic cancer. J Pancreas 7: 349-360
    • (2006) J Pancreas , vol.7 , pp. 349-360
    • Wilkowski, R.1    Thoma, M.2    Bruns, C.3    Wagner, A.4    Heinemann, V.5
  • 34
    • 27644505137 scopus 로고    scopus 로고
    • Chemoradiation for ductal pancreatic carcinoma: Principles of combining chemotherapy with radiation, definition of target volume and radiation dose
    • Wilkowski R, Thoma M, Weingandt H, Dühmke E, Heinemann V (2005) Chemoradiation for ductal pancreatic carcinoma: principles of combining chemotherapy with radiation, definition of target volume and radiation dose. J Pancreas 6: 216-230
    • (2005) J Pancreas , vol.6 , pp. 216-230
    • Wilkowski, R.1    Thoma, M.2    Weingandt, H.3    Dühmke, E.4    Heinemann, V.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.