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Volumn 31, Issue 2, 2007, Pages 151-156

Chemotherapy as initial treatment of locally advanced unresectable pancreatic cancer: A valid option?

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; FLUOROURACIL; FOLINIC ACID; GEMCITABINE; OXALIPLATIN;

EID: 33947134537     PISSN: 03998320     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0399-8320(07)89347-X     Document Type: Article
Times cited : (6)

References (24)
  • 2
    • 14544270277 scopus 로고    scopus 로고
    • Does anyone survive pancreatic ductal adenocarcinoma? A nationwide study re-evaluating the data of the Finnish Cancer Registry
    • Carpelan-Holmstrom M, Nordling S, Pukkala E, Sankila R, Luttges J, Kloppel G, et al. Does anyone survive pancreatic ductal adenocarcinoma? A nationwide study re-evaluating the data of the Finnish Cancer Registry. Gut 2005;54:385-7.
    • (2005) Gut , vol.54 , pp. 385-387
    • Carpelan-Holmstrom, M.1    Nordling, S.2    Pukkala, E.3    Sankila, R.4    Luttges, J.5    Kloppel, G.6
  • 4
    • 0014691062 scopus 로고
    • Combined 5-fluorouracil and supervoltage radiation therapy of locally unresectable gastrointestinal cancer
    • Moertel CG, Childs DS, Reitemeier RJ, Colby MY, Jr., Holbrook MA. Combined 5-fluorouracil and supervoltage radiation therapy of locally unresectable gastrointestinal cancer. Lancet 1969;2:865-7.
    • (1969) Lancet , vol.2 , pp. 865-867
    • Moertel, C.G.1    Childs, D.S.2    Reitemeier, R.J.3    Colby Jr., M.Y.4    Holbrook, M.A.5
  • 5
    • 0019410935 scopus 로고
    • Therapy of locally unresectable pancreatic carcinoma: A randomized comparison of high dose (6 000 rads) radiation alone, moderate dose radiation (4 000 rads + 5-fluorouracil), and high dose radiation + 5-fluorouracil: The Gastrointestinal Tumor Study Group
    • Moertel CG, Frytak S, Hahn RG, O'Connell MJ, Reitemeier RJ, Rubin J, et al. Therapy of locally unresectable pancreatic carcinoma: a randomized comparison of high dose (6 000 rads) radiation alone, moderate dose radiation (4 000 rads + 5-fluorouracil), and high dose radiation + 5-fluorouracil: The Gastrointestinal Tumor Study Group. Cancer 1981;48:1705-10.
    • (1981) Cancer , vol.48 , pp. 1705-1710
    • Moertel, C.G.1    Frytak, S.2    Hahn, R.G.3    O'Connell, M.J.4    Reitemeier, R.J.5    Rubin, J.6
  • 6
    • 0023722682 scopus 로고
    • Treatment of locally unresectable carcinoma of the pancreas: Comparison of combined-modality therapy (chemotherapy plus radiotherapy) to chemotherapy alone. Gastrointestinal Tumor Study Group
    • Treatment of locally unresectable carcinoma of the pancreas: comparison of combined-modality therapy (chemotherapy plus radiotherapy) to chemotherapy alone. Gastrointestinal Tumor Study Group. J Natl Cancer Inst 1988;80:751-5.
    • (1988) J Natl Cancer Inst , vol.80 , pp. 751-755
  • 7
    • 0018570114 scopus 로고
    • Comparative therapeutic trial of radiation with or without chemotherapy in pancreatic carcinoma. Gastrointestinal Tumor Study Group
    • Comparative therapeutic trial of radiation with or without chemotherapy in pancreatic carcinoma. Gastrointestinal Tumor Study Group. Int J Radiat Oncol Biol Phys 1979;5:1643-7.
    • (1979) Int J Radiat Oncol Biol Phys , vol.5 , pp. 1643-1647
  • 8
    • 0022225610 scopus 로고
    • Radiation therapy combined with Adriamycin or 5-fluorouracil for the treatment of locally unresectable pancreatic carcinoma. Gastrointestinal Tumor Study Group
    • Radiation therapy combined with Adriamycin or 5-fluorouracil for the treatment of locally unresectable pancreatic carcinoma. Gastrointestinal Tumor Study Group. Cancer 1985;56:2563-8.
    • (1985) Cancer , vol.56 , pp. 2563-2568
  • 9
    • 0025247936 scopus 로고
    • Hyperfractionated radiation and chemotherapy for unresectable localized adenocarcinoma of the pancreas. The Gastrointestinal Tumor Study Group experience
    • Seydel HG, Stablein DM, Leichman LP, Kinzie JJ, Thomas PR. Hyperfractionated radiation and chemotherapy for unresectable localized adenocarcinoma of the pancreas. The Gastrointestinal Tumor Study Group experience. Cancer 1990;65:1478-82.
    • (1990) Cancer , vol.65 , pp. 1478-1482
    • Seydel, H.G.1    Stablein, D.M.2    Leichman, L.P.3    Kinzie, J.J.4    Thomas, P.R.5
  • 11
    • 8244254377 scopus 로고    scopus 로고
    • Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial
    • Burris HA, III, Moore MJ, Andersen J, Green MR, Rothenberg ML, Modiano MR, et al. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol 1997;15:2403-13.
    • (1997) J Clin Oncol , vol.15 , pp. 2403-2413
    • Burris III, H.A.1    Moore, M.J.2    Andersen, J.3    Green, M.R.4    Rothenberg, M.L.5    Modiano, M.R.6
  • 12
    • 17544403541 scopus 로고    scopus 로고
    • Chimiothérapie des adénocarcinomes du pancréas non résécables par 5-fluorouracile, acide folinique et cisplatine (LV5FU2-P)
    • Taieb J, Lecomte T, Ezenfis J, Artru P, Mitry E, Boige V, et al. Chimiothérapie des adénocarcinomes du pancréas non résécables par 5-fluorouracile, acide folinique et cisplatine (LV5FU2-P). Gastroenterol Clin Biol 2002;26:605-9.
    • (2002) Gastroenterol Clin Biol , vol.26 , pp. 605-609
    • Taieb, J.1    Lecomte, T.2    Ezenfis, J.3    Artru, P.4    Mitry, E.5    Boige, V.6
  • 13
    • 0037083621 scopus 로고    scopus 로고
    • Gemcitabine alone or with cisplatin for the treatment of patients with locally advanced and/or metastatic pancreatic carcinoma: A prospective, randomized phase III study of the Gruppo Oncologia dell'Italia Meridionale
    • Colucci G, Giuliani F, Gebbia V, Biglietto M, Rabitti P, Uomo G, et al. Gemcitabine alone or with cisplatin for the treatment of patients with locally advanced and/or metastatic pancreatic carcinoma: a prospective, randomized phase III study of the Gruppo Oncologia dell'Italia Meridionale. Cancer 2002;94:902-10.
    • (2002) Cancer , vol.94 , pp. 902-910
    • Colucci, G.1    Giuliani, F.2    Gebbia, V.3    Biglietto, M.4    Rabitti, P.5    Uomo, G.6
  • 14
    • 20644464360 scopus 로고    scopus 로고
    • Gemcitabine in combination with oxaliplatin compared with gemcitabine alone in locally advanced or metastatic pancreatic cancer: Results of a GERCOR and GISCAD phase III trial
    • Louvet C, Labianca R, Hammel P, Lledo G, Zampino MG, Andre T, et al. Gemcitabine in combination with oxaliplatin compared with gemcitabine alone in locally advanced or metastatic pancreatic cancer: results of a GERCOR and GISCAD phase III trial. J Clin Oncol 2005;23:3509-16.
    • (2005) J Clin Oncol , vol.23 , pp. 3509-3516
    • Louvet, C.1    Labianca, R.2    Hammel, P.3    Lledo, G.4    Zampino, M.G.5    Andre, T.6
  • 15
    • 33845382806 scopus 로고
    • Nonparametric estimation for incomplete observations
    • Kaplan EL, Meier P. Nonparametric estimation for incomplete observations. J Am Stat Assoc 1958;53:457-481.
    • (1958) J Am Stat Assoc , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 16
    • 0021918519 scopus 로고
    • Treatment of locally unresectable cancer of the stomach and pancreas: A randomized comparison of 5-fluorouracil alone with radiation plus concurrent and maintenance 5-fluorouracil - an Eastern Cooperative Oncology Group study
    • Klaassen DJ, MacIntyre JM, Catton GE, Engstrom PF, Moertel CG. Treatment of locally unresectable cancer of the stomach and pancreas: a randomized comparison of 5-fluorouracil alone with radiation plus concurrent and maintenance 5-fluorouracil - an Eastern Cooperative Oncology Group study. J Clin Oncol 1985;3:373-8.
    • (1985) J Clin Oncol , vol.3 , pp. 373-378
    • Klaassen, D.J.1    MacIntyre, J.M.2    Catton, G.E.3    Engstrom, P.F.4    Moertel, C.G.5
  • 17
    • 0022859675 scopus 로고
    • Phase II studies of drug combinations in advanced pancreatic carcinoma: Fluorouracil plus doxorubicin plus mitomycin C and two regimens of streptozotocin plus mitomycin C plus fluorouracil. The Gastrointestinal Tumor Study Group
    • Phase II studies of drug combinations in advanced pancreatic carcinoma: fluorouracil plus doxorubicin plus mitomycin C and two regimens of streptozotocin plus mitomycin C plus fluorouracil. The Gastrointestinal Tumor Study Group. J Clin Oncol 1986;4:1794-8.
    • (1986) J Clin Oncol , vol.4 , pp. 1794-1798
  • 18
    • 0038048218 scopus 로고    scopus 로고
    • Postoperative adjuvant gemcitabine and concurrent radiation after curative resection of pancreatic head carcinoma: A phase II study
    • Van Laethem JL, Demols A, Gay F, Closon MT, Collette M, Polus M, et al. Postoperative adjuvant gemcitabine and concurrent radiation after curative resection of pancreatic head carcinoma: a phase II study. Int J Radiat Oncol Biol Phys 2003;56:974-80.
    • (2003) Int J Radiat Oncol Biol Phys , vol.56 , pp. 974-980
    • Van Laethem, J.L.1    Demols, A.2    Gay, F.3    Closon, M.T.4    Collette, M.5    Polus, M.6
  • 19
    • 4344626528 scopus 로고    scopus 로고
    • Phase II study of radiotherapy combined with gemcitabine for locally advanced pancreatic cancer
    • Okusaka T, Ito Y, Ueno H, Ikeda M, Takezako Y, Morizane C, et al. Phase II study of radiotherapy combined with gemcitabine for locally advanced pancreatic cancer. Br J Cancer 2004;91:673-7.
    • (2004) Br J Cancer , vol.91 , pp. 673-677
    • Okusaka, T.1    Ito, Y.2    Ueno, H.3    Ikeda, M.4    Takezako, Y.5    Morizane, C.6
  • 21
    • 27644493712 scopus 로고    scopus 로고
    • Randomized phase II - study evaluating EGFR targeting therapy with cetuximab in combination with radiotherapy and chemotherapy for patients with locally advanced pancreatic cancer - PARC: Study protocol [ISRCTN56652283]
    • Krempien R, Muenter MW, Huber PE, Nill S, Friess H, Timke C, et al. Randomized phase II - study evaluating EGFR targeting therapy with cetuximab in combination with radiotherapy and chemotherapy for patients with locally advanced pancreatic cancer - PARC: study protocol [ISRCTN56652283]. BMC Cancer 2005;5:131.
    • (2005) BMC Cancer , vol.5 , pp. 131
    • Krempien, R.1    Muenter, M.W.2    Huber, P.E.3    Nill, S.4    Friess, H.5    Timke, C.6
  • 22
    • 85030515735 scopus 로고    scopus 로고
    • Chemoradiotherapy (CRT) after chemotherapy (CT) improves survival for locally-advanced (LA) pancreatic cancer patients: Retrospective analysis of 181 patients enrolled in prospective phases II and III GERCOR studies
    • Huguet F, Andre T, Hammel P, Artru P, Balosso J, Ruszniewski P, et al. Chemoradiotherapy (CRT) after chemotherapy (CT) improves survival for locally-advanced (LA) pancreatic cancer patients: retrospective analysis of 181 patients enrolled in prospective phases II and III GERCOR studies. Proc Am Soc Clin Oncol 2005;23:16S. A4095.
    • Proc Am Soc Clin Oncol 2005;23:16S. A4095
    • Huguet, F.1    Andre, T.2    Hammel, P.3    Artru, P.4    Balosso, J.5    Ruszniewski, P.6
  • 23
    • 23944459082 scopus 로고    scopus 로고
    • Surgical resection after radiochemotherapy in patients with unresectable adenocarcinoma of the pancreas
    • Sa Cunha A, Rault A, Laurent C, Adhoute X, Vendrely V, Bellannée G, et al. Surgical resection after radiochemotherapy in patients with unresectable adenocarcinoma of the pancreas. J Am Coll Surg 2005;201:359-65.
    • (2005) J Am Coll Surg , vol.201 , pp. 359-365
    • Sa Cunha, A.1    Rault, A.2    Laurent, C.3    Adhoute, X.4    Vendrely, V.5    Bellannée, G.6
  • 24
    • 12144287320 scopus 로고    scopus 로고
    • A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer
    • Neoptolemos JP, Stocken DD, Friess H, Bassi C, Dunn JA, Hickey H, et al. A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer. N Engl J Med 2004;350:1200-10.
    • (2004) N Engl J Med , vol.350 , pp. 1200-1210
    • Neoptolemos, J.P.1    Stocken, D.D.2    Friess, H.3    Bassi, C.4    Dunn, J.A.5    Hickey, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.