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Volumn 106, Issue 6, 2008, Pages 2502-2514

Neuroactive steroids and GABAA receptor plasticity in the brain of the WAG/Rij rat, a model of absence epilepsy

Author keywords

Absence epilepsy; GABAA receptor; Neuroactive steroid; WAG Rij rat

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 3ALPHA,5ALPHA TETRAHYDRODEOXYCORTICOSTERONE; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA4; 4 AMINOBUTYRIC ACID A RECEPTOR DELTA; STEROID; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID; DEOXYCORTICOSTERONE; DRUG DERIVATIVE; ELTANOLONE; PREGNANE 20 ONE; PREGNANE-20-ONE; PROTEIN SUBUNIT; TETRAHYDRODEOXYCORTICOSTERONE;

EID: 50849103629     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2008.05538.x     Document Type: Article
Times cited : (20)

References (73)
  • 2
    • 0031799363 scopus 로고    scopus 로고
    • International Union of Pharmacology. XV. Subtypes of γ-aminobutyric acid a receptors: Classification on the basis of subunit structure and receptor function
    • Barnard E. A., Skolnick P., Olsen R. W., Mohòer H., Sieghart W., Biggio G., Braestrup C., Bateson A. N. Langer S. Z. (1998) International Union of Pharmacology. XV. Subtypes of γ-aminobutyric acid A receptors: classification on the basis of subunit structure and receptor function. Pharmacol. Rev. 50, 291 313.
    • (1998) Pharmacol. Rev. , vol.50 , pp. 291-313
    • Barnard, E.A.1    Skolnick, P.2    Olsen, R.W.3    Mohòer, H.4    Sieghart, W.5    Biggio, G.6    Braestrup, C.7    Bateson, A.N.8    Langer, S.Z.9
  • 6
    • 32944476501 scopus 로고    scopus 로고
    • Cellular and network mechanism of spike-wave seizures
    • Blumenfeld H. (2005) Cellular and network mechanism of spike-wave seizures. Epilepsia 46, 21 33.
    • (2005) Epilepsia , vol.46 , pp. 21-33
    • Blumenfeld, H.1
  • 9
    • 1242328701 scopus 로고    scopus 로고
    • Chronic intermittent ethanol (CIE) administration in rats decreases levels of neurosteroids in hippocampus, accompanied by altered behavioral responses to neurosteroids and memory function
    • Cagetti E., Pinna G., Guidotti A., Baicy K. Olsen R. W. (2004) Chronic intermittent ethanol (CIE) administration in rats decreases levels of neurosteroids in hippocampus, accompanied by altered behavioral responses to neurosteroids and memory function. Neuropharmacology 46, 570 579.
    • (2004) Neuropharmacology , vol.46 , pp. 570-579
    • Cagetti, E.1    Pinna, G.2    Guidotti, A.3    Baicy, K.4    Olsen, R.W.5
  • 10
    • 33750089730 scopus 로고    scopus 로고
    • A receptor α4 subunits mediate extrasynaptic inhibition in thalamus and dentate gyrus and the action of gaboxadol
    • A receptor α4 subunits mediate extrasynaptic inhibition in thalamus and dentate gyrus and the action of gaboxadol. Proc. Natl Acad. Sci. USA 103, 15230 15235.
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 15230-15235
    • Chandra, D.1    Jia, F.2    Liang, J.3
  • 11
    • 33744549505 scopus 로고    scopus 로고
    • Effects of some neurosteroids injected into some brain areas of WAG/Rij rats, an animal model of generalized absence epilepsy
    • Citraro R., Russo E., Di Paola E., Ibbadu G. F., Gratteri S., Marra R. De Sarro G. (2006) Effects of some neurosteroids injected into some brain areas of WAG/Rij rats, an animal model of generalized absence epilepsy. Neuropharmacology 50, 1059 1071.
    • (2006) Neuropharmacology , vol.50 , pp. 1059-1071
    • Citraro, R.1    Russo, E.2    Di Paola, E.3    Ibbadu, G.F.4    Gratteri, S.5    Marra, R.6    De Sarro, G.7
  • 12
    • 0024502037 scopus 로고
    • Effects of diazepam and two β-carbolines on epileptic activity and on EEG and behavior in rats with absence seizures
    • Coenen A. M. van Luijtelaar G. (1989) Effects of diazepam and two β-carbolines on epileptic activity and on EEG and behavior in rats with absence seizures. Pharmacol. Biochem. Behav. 32, 27 35.
    • (1989) Pharmacol. Biochem. Behav. , vol.32 , pp. 27-35
    • Coenen, A.M.1    Van Luijtelaar, G.2
  • 13
    • 0345256499 scopus 로고    scopus 로고
    • Genetic animal models for absence epilepsy: A review of the WAG/Rij strain of rats
    • Coenen A. M. van Luijtelaar G. (2003) Genetic animal models for absence epilepsy: a review of the WAG/Rij strain of rats. Behav. Genet. 33, 635 655.
    • (2003) Behav. Genet. , vol.33 , pp. 635-655
    • Coenen, A.M.1    Van Luijtelaar, G.2
  • 14
    • 0032573169 scopus 로고    scopus 로고
    • Role of brain allopregnanolone in the plasticity of γ-aminobutyric acid type a receptor in the rat brain during pregnancy and after delivery
    • Concas A., Mostallino M. C., Perra C. et al. (1998) Role of brain allopregnanolone in the plasticity of γ-aminobutyric acid type A receptor in the rat brain during pregnancy and after delivery. Proc. Natl Acad. Sci. USA 95, 13284 13289.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 13284-13289
    • Concas, A.1    Mostallino, M.C.2    Perra, C.3
  • 16
    • 30744441624 scopus 로고    scopus 로고
    • A receptor-mediated tonic inhibition in thalamic neurons
    • A receptor-mediated tonic inhibition in thalamic neurons. J. Neurosci. 25, 11553 11563.
    • (2005) J. Neurosci. , vol.25 , pp. 11553-11563
    • Cope, D.W.1    Hughes, S.W.2    Crunelli, V.3
  • 17
    • 0021273690 scopus 로고
    • Electrophysiology of neurons of lateral thalamic nuclei in cat: Resting properties and burst discharges
    • Deschênes M., Paradis M., Roy J. P. Steriade M. (1984) Electrophysiology of neurons of lateral thalamic nuclei in cat: resting properties and burst discharges. J. Neurophysiol. 51, 1196 1219.
    • (1984) J. Neurophysiol. , vol.51 , pp. 1196-1219
    • Deschênes, M.1    Paradis, M.2    Roy, J.P.3    Steriade, M.4
  • 20
    • 0023133617 scopus 로고
    • The THIP-induced model of bilateral synchronous spike and wave in rodents
    • Fariello R. G. Golden G. T. (1987) The THIP-induced model of bilateral synchronous spike and wave in rodents. Neuropharmacology 26, 161 165.
    • (1987) Neuropharmacology , vol.26 , pp. 161-165
    • Fariello, R.G.1    Golden, G.T.2
  • 24
    • 23244463624 scopus 로고    scopus 로고
    • Distinct patterns of expression and regulation of GABA receptors containing the delta subunit in cerebellar granule and hippocampal neurons
    • Follesa P., Mostallino M. C., Biggio F. et al. (2005) Distinct patterns of expression and regulation of GABA receptors containing the delta subunit in cerebellar granule and hippocampal neurons. J. Neurochem. 94, 659 671.
    • (2005) J. Neurochem. , vol.94 , pp. 659-671
    • Follesa, P.1    Mostallino, M.C.2    Biggio, F.3
  • 25
    • 0026648083 scopus 로고
    • Five subtypes of type a γ-aminobutyric acid receptors identified in neurons by double and triple immunofluorescence staining with subunit-specific antibodies
    • Fritschy J. M., Benke D., Mertens S., Oertel W. H., Bachi T. Möhler H. (1992) Five subtypes of type A γ-aminobutyric acid receptors identified in neurons by double and triple immunofluorescence staining with subunit-specific antibodies. Proc. Natl Acad. Sci. USA 89, 6726 6730.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 6726-6730
    • Fritschy, J.M.1    Benke, D.2    Mertens, S.3    Oertel, W.H.4    Bachi, T.5    Möhler, H.6
  • 26
    • 27744493861 scopus 로고    scopus 로고
    • A receptor subunits: Plasticity of expression during the estrous cycle
    • A receptor subunits: plasticity of expression during the estrous cycle. Neuroscience 36, 457 466.
    • (2005) Neuroscience , vol.36 , pp. 457-466
    • Griffiths, J.L.1    Lovick, T.A.2
  • 27
    • 0035225433 scopus 로고    scopus 로고
    • Physiological roles for the neurosteroid allopregnanolone in the modulation of brain function during pregnancy and parturition
    • Herbison A. E. (2001) Physiological roles for the neurosteroid allopregnanolone in the modulation of brain function during pregnancy and parturition. Prog. Brain Res. 133, 39 47.
    • (2001) Prog. Brain Res. , vol.133 , pp. 39-47
    • Herbison, A.E.1
  • 28
    • 0031024530 scopus 로고    scopus 로고
    • The idiopathic generalized epilepsies of adolescence with childhood and juvenile age of onset
    • Janz D. (1997) The idiopathic generalized epilepsies of adolescence with childhood and juvenile age of onset. Epilepsia 38, 4 11.
    • (1997) Epilepsia , vol.38 , pp. 4-11
    • Janz, D.1
  • 31
    • 0027169922 scopus 로고
    • Cellular mechanisms of a synchronized oscillation in the thalamus
    • von Krosigk M., Bal T. McCormick D. A. (1993) Cellular mechanisms of a synchronized oscillation in the thalamus. Science 261, 361 364.
    • (1993) Science , vol.261 , pp. 361-364
    • Von Krosigk, M.1    Bal, T.2    McCormick, D.A.3
  • 32
    • 0036584661 scopus 로고    scopus 로고
    • Childhood absence epilepsy: Genes, channels, neurons and network
    • Leresche N. Crunelli V. (2002) Childhood absence epilepsy: genes, channels, neurons and network. Nat. Rev. Neurosci. 3, 371 382.
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 371-382
    • Leresche, N.1    Crunelli, V.2
  • 33
    • 34547644482 scopus 로고    scopus 로고
    • Reticular nucleus-specific changes in α3 subunit protein at GABA synapses in genetically epilepsy-prone rats
    • Liu X. B., Coble J., van Luijtelaar G. Jones E. G. (2007) Reticular nucleus-specific changes in α3 subunit protein at GABA synapses in genetically epilepsy-prone rats. Proc. Natl Acad. Sci. USA 104, 12512 12517.
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 12512-12517
    • Liu, X.B.1    Coble, J.2    Van Luijtelaar, G.3    Jones, E.G.4
  • 34
    • 8844256125 scopus 로고    scopus 로고
    • Case-control study and transmission/disequilibrium tests of the genes encoding GABRA5 and GABRB3 in a Chinese population affected by childhood absence epilepsy
    • Lü J. J., Zhang Y. H., Pan H. et al. (2004) Case-control study and transmission/disequilibrium tests of the genes encoding GABRA5 and GABRB3 in a Chinese population affected by childhood absence epilepsy. Chin. Med. J. (Engl.) 117, 1497 1501.
    • (2004) Chin. Med. J. (Engl.) , vol.117 , pp. 1497-1501
    • Lü, J.J.1    Zhang, Y.H.2    Pan, H.3
  • 35
    • 50849143329 scopus 로고    scopus 로고
    • The ovarian hormones and absence epilepsy: A long-term EEG study and pharmacological effects in a genetic absence epilepsy model
    • van Luijtelaar G., Budziszewska B., Jaworska-Feil L., Ellis J., Coenen A. M. Lasón W. (2001) The ovarian hormones and absence epilepsy: a long-term EEG study and pharmacological effects in a genetic absence epilepsy model. Epilepsy Res. 9, 148 153.
    • (2001) Epilepsy Res. , vol.9 , pp. 148-153
    • Van Luijtelaar, G.1    Budziszewska, B.2    Jaworska-Feil, L.3    Ellis, J.4    Coenen, A.M.5    Lasón, W.6
  • 36
    • 0142042971 scopus 로고    scopus 로고
    • Finasteride inhibits the progesterone-induced spike-wave discharges in a genetic model of absence epilepsy
    • van Luijtelaar G., Budziszewska B., Tetich M. Lasón W. (2003) Finasteride inhibits the progesterone-induced spike-wave discharges in a genetic model of absence epilepsy. Pharmacol. Biochem. Behav. 75, 889 894.
    • (2003) Pharmacol. Biochem. Behav. , vol.75 , pp. 889-894
    • Van Luijtelaar, G.1    Budziszewska, B.2    Tetich, M.3    Lasón, W.4
  • 38
    • 0033585890 scopus 로고    scopus 로고
    • Subunit dependent modulation of GABAA receptor function by neuroactive steroids
    • Maitra R. Reynolds J. N. (1999) Subunit dependent modulation of GABAA receptor function by neuroactive steroids. Brain Res. 819, 75 82.
    • (1999) Brain Res. , vol.819 , pp. 75-82
    • Maitra, R.1    Reynolds, J.N.2
  • 39
    • 0022483382 scopus 로고
    • Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor
    • Majewska M. D., Harrison N. L., Schartz R. D., Barker J. L. Paul S. M. (1986) Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor. Science 232, 1004 1007.
    • (1986) Science , vol.232 , pp. 1004-1007
    • Majewska, M.D.1    Harrison, N.L.2    Schartz, R.D.3    Barker, J.L.4    Paul, S.M.5
  • 41
    • 0037083650 scopus 로고    scopus 로고
    • Cortical focus drives widespread corticothalamic networks during spontaneous absence seizures in rats
    • Meeren H. K., Pijn J. P., van Luijtelaar E. L., Coenen A. M. Lopes da Silva F. H. (2002) Cortical focus drives widespread corticothalamic networks during spontaneous absence seizures in rats. J. Neurosci. 22, 1480 1495.
    • (2002) J. Neurosci. , vol.22 , pp. 1480-1495
    • Meeren, H.K.1    Pijn, J.P.2    Van Luijtelaar, E.L.3    Coenen, A.M.4    Lopes Da Silva, F.H.5
  • 42
    • 0036940599 scopus 로고    scopus 로고
    • Synthesis, regulation, and function of neurosteroids
    • Mellon S. H. Griffin L. D. (2002) Synthesis, regulation, and function of neurosteroids. Endocr. Res. 28, 463.
    • (2002) Endocr. Res. , vol.28 , pp. 463
    • Mellon, S.H.1    Griffin, L.D.2
  • 43
    • 0034764735 scopus 로고    scopus 로고
    • A receptors responsible for tonic and phasic conductances
    • A receptors responsible for tonic and phasic conductances. Neurochem. Res. 26, 907 913.
    • (2001) Neurochem. Res. , vol.26 , pp. 907-913
    • Mody, I.1
  • 45
    • 0035577640 scopus 로고    scopus 로고
    • Diminished allopregnanolone enhancement of GABA(A) receptor currents a rat model of chronic temporal epilepsy
    • Mtchedlishvili Z., Bertram E. H. Kapur J. (2001) Diminished allopregnanolone enhancement of GABA(A) receptor currents a rat model of chronic temporal epilepsy. J. Physiol. 537, 453 465.
    • (2001) J. Physiol. , vol.537 , pp. 453-465
    • Mtchedlishvili, Z.1    Bertram, E.H.2    Kapur, J.3
  • 46
    • 0028981679 scopus 로고
    • Modulation of GABAA receptor binding in human brain by neuroactive steroids: Species and brain regional differences
    • Nguyen Q., Sapp D. W., Van Ness P. C. Olsen R. W. (1995) Modulation of GABAA receptor binding in human brain by neuroactive steroids: species and brain regional differences. Synapse 19, 77 87.
    • (1995) Synapse , vol.19 , pp. 77-87
    • Nguyen, Q.1    Sapp, D.W.2    Van Ness, P.C.3    Olsen, R.W.4
  • 47
    • 0036097970 scopus 로고    scopus 로고
    • Selective modulation of tonic and phasic inhibition in dentate gyrus granule cells
    • Nusser Z. Mody I. (2002) Selective modulation of tonic and phasic inhibition in dentate gyrus granule cells. J. Neurophysiol. 87, 2624 2628.
    • (2002) J. Neurophysiol. , vol.87 , pp. 2624-2628
    • Nusser, Z.1    Mody, I.2
  • 48
    • 0032008543 scopus 로고    scopus 로고
    • A receptors to synaptic and extrasynaptic membrane of cerebellar granule cells
    • A receptors to synaptic and extrasynaptic membrane of cerebellar granule cells. J. Neurosci. 18, 1693 1703.
    • (1998) J. Neurosci. , vol.18 , pp. 1693-1703
    • Nusser, Z.1    Sieghart, W.2    Somogyi, P.3
  • 50
    • 0024474236 scopus 로고
    • Effects of GABA-ergic agents on spontaneous non-convulsive epilepsy, EEG and behavior, in the WAG/Rij inbred strain of rats
    • Peeters B. W., van Rijn C. M., Vossen J. M. Coenen A. M. L. (1989) Effects of GABA-ergic agents on spontaneous non-convulsive epilepsy, EEG and behavior, in the WAG/Rij inbred strain of rats. Life Sci. 45, 1171 1176.
    • (1989) Life Sci. , vol.45 , pp. 1171-1176
    • Peeters, B.W.1    Van Rijn, C.M.2    Vossen, J.M.3    Coenen, A.M.L.4
  • 53
    • 0025353194 scopus 로고
    • Synthesis, metabolism and pharmacological activity of 3α-hydroxy-steroids which potentiate GABA-receptor-mediated chloride ion uptake in rat cerebral cortical synaptoneurosomes
    • Purdy R. H., Morrow A. L., Blinn J. R. Paul S. M. (1990) Synthesis, metabolism and pharmacological activity of 3α-hydroxy-steroids which potentiate GABA-receptor-mediated chloride ion uptake in rat cerebral cortical synaptoneurosomes. J. Med. Chem. 33, 1572 1581.
    • (1990) J. Med. Chem. , vol.33 , pp. 1572-1581
    • Purdy, R.H.1    Morrow, A.L.2    Blinn, J.R.3    Paul, S.M.4
  • 54
    • 1642397435 scopus 로고    scopus 로고
    • Nifedipine affects the anticonvulsant activity of topiramate in various animal models of epilepsy
    • Russo E., Constanti A., Ferreri G., Citraro R. De Sarro G. (2004) Nifedipine affects the anticonvulsant activity of topiramate in various animal models of epilepsy. Neuropharmacology 46, 865 878.
    • (2004) Neuropharmacology , vol.46 , pp. 865-878
    • Russo, E.1    Constanti, A.2    Ferreri, G.3    Citraro, R.4    De Sarro, G.5
  • 56
    • 14844313707 scopus 로고    scopus 로고
    • The role of the environment on the development of spike-wave discharges in two strains of rats
    • Schridde U. van Luijtelaar G. (2005) The role of the environment on the development of spike-wave discharges in two strains of rats. Physiol. Behav. 84, 379 386.
    • (2005) Physiol. Behav. , vol.84 , pp. 379-386
    • Schridde, U.1    Van Luijtelaar, G.2
  • 57
    • 23944497525 scopus 로고    scopus 로고
    • Neurosteroids exhibit differential effects on mIPSCs recorded from normal and seizure prone rats
    • Schwabe K., Gabrilovici C., McIntyre D. C. Poulter M. O. (2005) Neurosteroids exhibit differential effects on mIPSCs recorded from normal and seizure prone rats. J. Neurophysiol. 94, 2171 2181.
    • (2005) J. Neurophysiol. , vol.94 , pp. 2171-2181
    • Schwabe, K.1    Gabrilovici, C.2    McIntyre, D.C.3    Poulter, M.O.4
  • 60
    • 33745081530 scopus 로고    scopus 로고
    • Social isolation-induced increase in alpha and delta subunit gene expression is associated with a greater efficacy of ethanol on steroidogenesis and GABA receptor function
    • Serra M., Mostallino M. C., Talani G. et al. (2006) Social isolation-induced increase in alpha and delta subunit gene expression is associated with a greater efficacy of ethanol on steroidogenesis and GABA receptor function. J. Neurochem. 98, 122 133.
    • (2006) J. Neurochem. , vol.98 , pp. 122-133
    • Serra, M.1    Mostallino, M.C.2    Talani, G.3
  • 61
    • 0037088936 scopus 로고    scopus 로고
    • Activity of thalamic reticular neurons during spontaneous genetically determined spike and wave discharges
    • Slaght S. J., Leresche N., Deniau J. M., Crunelli V. Charpier S. (2002) Activity of thalamic reticular neurons during spontaneous genetically determined spike and wave discharges. J. Neurosci. 22, 2323 2334.
    • (2002) J. Neurosci. , vol.22 , pp. 2323-2334
    • Slaght, S.J.1    Leresche, N.2    Deniau, J.M.3    Crunelli, V.4    Charpier, S.5
  • 64
    • 0028896579 scopus 로고
    • Basic mechanisms of generalized absence seizures
    • Snead O. C. (1995) Basic mechanisms of generalized absence seizures. Ann. Neurol. 37, 146 157.
    • (1995) Ann. Neurol. , vol.37 , pp. 146-157
    • Snead, O.C.1
  • 65
    • 20144365152 scopus 로고    scopus 로고
    • Sleep, epilepsy and thalamic reticular inhibitory neurons
    • Steriade M. (2005) Sleep, epilepsy and thalamic reticular inhibitory neurons. Trends Neurosci. 28, 317 324.
    • (2005) Trends Neurosci. , vol.28 , pp. 317-324
    • Steriade, M.1
  • 66
    • 0021715728 scopus 로고
    • The thalamus as a neuronal oscillator
    • Steriade M. Deschênes M. (1984) The thalamus as a neuronal oscillator. Brain Res. Rev. 8, 1 63.
    • (1984) Brain Res. Rev. , vol.8 , pp. 1-63
    • Steriade, M.1    Deschênes, M.2
  • 70
    • 0035033520 scopus 로고    scopus 로고
    • A receptor γ2-subunit in childhood absence epilepsy and febrile seizures
    • A receptor γ2-subunit in childhood absence epilepsy and febrile seizures. Nat. Genet. 28, 49 52.
    • (2001) Nat. Genet. , vol.28 , pp. 49-52
    • Wallace, R.H.1    Marini, C.2    Petrou, S.3
  • 71
    • 0344442662 scopus 로고    scopus 로고
    • A receptors and their activation by GABA spillover in the mouse dentate gyrus
    • A receptors and their activation by GABA spillover in the mouse dentate gyrus. J. Neurosci. 23, 10650 10661.
    • (2003) J. Neurosci. , vol.23 , pp. 10650-10661
    • Wei, W.1    Zhang, N.2    Peng, Z.3    Houser, C.R.4    Mody, I.5
  • 72
    • 0033009936 scopus 로고    scopus 로고
    • Molecular and functional diversity of the expanding GABA-A receptor gene family
    • Whiting P. J., Bonnert T. P., McKernan R. M. et al. (1999) Molecular and functional diversity of the expanding GABA-A receptor gene family. Ann. NY Acad. Sci. 868, 645 653.
    • (1999) Ann. NY Acad. Sci. , vol.868 , pp. 645-653
    • Whiting, P.J.1    Bonnert, T.P.2    McKernan, R.M.3
  • 73
    • 0026612363 scopus 로고
    • A receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon
    • A receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon. J. Neurosci. 12, 1040 1062.
    • (1992) J. Neurosci. , vol.12 , pp. 1040-1062
    • Wisden, W.1    Laurie, D.J.2    Monyer, H.3    Seeburg, P.H.4


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