메뉴 건너뛰기




Volumn 123, Issue 7, 2008, Pages 1516-1525

SV40 large T antigen-transformed human primary normal and cancerous mammary epithelial cells are phenotypically similar but can be distinguished in 3D culture with selection medium

Author keywords

3D culture; Genomic instability; Immortality; Mammary carcinoma; SV40 large T; Telomerase

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; TELOMERASE; VIRUS LARGE T ANTIGEN; CRE RECOMBINASE; INTEGRASE; MICROSATELLITE DNA; SMALL INTERFERING RNA; VIRUS T ANTIGEN;

EID: 50549097195     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.23657     Document Type: Article
Times cited : (4)

References (50)
  • 1
    • 0025729836 scopus 로고
    • Defining the molecular mechanisms of human cell immortalization
    • Shay JW, Wright WE, Werbin H. Defining the molecular mechanisms of human cell immortalization. Biochim Biophys Acta 1991;1072:1-7.
    • (1991) Biochim Biophys Acta , vol.1072 , pp. 1-7
    • Shay, J.W.1    Wright, W.E.2    Werbin, H.3
  • 2
    • 0030038104 scopus 로고    scopus 로고
    • Replicative senescence: Implications for in vivo aging and tumor suppression
    • Smith JR, Pereira-Smith OM. Replicative senescence: implications for in vivo aging and tumor suppression. Science 1996;273:63-7.
    • (1996) Science , vol.273 , pp. 63-67
    • Smith, J.R.1    Pereira-Smith, O.M.2
  • 5
    • 0028322713 scopus 로고
    • SV40-induced immortalization of human cells
    • Bryan TM, Reddel RR. SV40-induced immortalization of human cells. Crit Rev Oncog 1994;5:331-57.
    • (1994) Crit Rev Oncog , vol.5 , pp. 331-357
    • Bryan, T.M.1    Reddel, R.R.2
  • 6
    • 0024366596 scopus 로고
    • Reversible cellular senescence: Implications for immortalization of normal human diploid fibroblasts
    • Wright WE, Pereira-Smith OM, Shay JW. Reversible cellular senescence: implications for immortalization of normal human diploid fibroblasts. Mol Cell Biol 1989;9:3088-92.
    • (1989) Mol Cell Biol , vol.9 , pp. 3088-3092
    • Wright, W.E.1    Pereira-Smith, O.M.2    Shay, J.W.3
  • 8
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 9
    • 0019973132 scopus 로고
    • Induction of immortality is an early event in malignant transformation of mammalian cells by carcinogens
    • Newbold RF, Overell RW, Connell JR. Induction of immortality is an early event in malignant transformation of mammalian cells by carcinogens. Nature 1982;299:633-5.
    • (1982) Nature , vol.299 , pp. 633-635
    • Newbold, R.F.1    Overell, R.W.2    Connell, J.R.3
  • 12
    • 0030937486 scopus 로고    scopus 로고
    • Partial enzymatic degradation of stroma allows enrichment and expansion of primary breast tumor cells
    • Dairkee SH, Paulo EC, Traquina P, Moore DH, Ljung BM, Smith HS. Partial enzymatic degradation of stroma allows enrichment and expansion of primary breast tumor cells. Cancer Res 1997;57:1590-6.
    • (1997) Cancer Res , vol.57 , pp. 1590-1596
    • Dairkee, S.H.1    Paulo, E.C.2    Traquina, P.3    Moore, D.H.4    Ljung, B.M.5    Smith, H.S.6
  • 13
    • 0024512996 scopus 로고
    • Distinctive traits of normal and tumor-derived human mammary epithelial cells expressed in a medium that supports long-term growth of both cell types
    • Band V, Sager R. Distinctive traits of normal and tumor-derived human mammary epithelial cells expressed in a medium that supports long-term growth of both cell types. Proc Natl Acad Sci USA 1989;86:1249-53.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 1249-1253
    • Band, V.1    Sager, R.2
  • 14
    • 17344363706 scopus 로고    scopus 로고
    • Transient expression of SV 40 large T antigen by Cre/LoxP-mediated site-specific deletion in primary human tumor cells
    • Li LP, Schlag PM, Blankenstein T. Transient expression of SV 40 large T antigen by Cre/LoxP-mediated site-specific deletion in primary human tumor cells. Hum Gene Ther 1997;8:1695-700.
    • (1997) Hum Gene Ther , vol.8 , pp. 1695-1700
    • Li, L.P.1    Schlag, P.M.2    Blankenstein, T.3
  • 15
    • 0033968404 scopus 로고    scopus 로고
    • Interleukin-7/B7.1-encoding adenoviruses induce rejection of transplanted but not nontransplanted tumors
    • Willimsky G, Blankenstein T. Interleukin-7/B7.1-encoding adenoviruses induce rejection of transplanted but not nontransplanted tumors. Cancer Res 2000;60:685-92.
    • (2000) Cancer Res , vol.60 , pp. 685-692
    • Willimsky, G.1    Blankenstein, T.2
  • 16
    • 0030697807 scopus 로고    scopus 로고
    • PD153035, a tyrosine kinase inhibitor, prevents epidermal growth factor receptor activation and inhibits growth of cancer cells in a receptor number-dependent manner
    • Bos M, Mendelsohn J, Kim YM, Albanell J, Fry DW, Baselga J. PD153035, a tyrosine kinase inhibitor, prevents epidermal growth factor receptor activation and inhibits growth of cancer cells in a receptor number-dependent manner. Clin Cancer Res 1997;3:2099-106.
    • (1997) Clin Cancer Res , vol.3 , pp. 2099-2106
    • Bos, M.1    Mendelsohn, J.2    Kim, Y.M.3    Albanell, J.4    Fry, D.W.5    Baselga, J.6
  • 17
    • 0025195628 scopus 로고
    • Modulation of a Mr 175,000 c-neu receptor isoform in G8/DHFR cells by serum starvation
    • Epstein RJ, Druker BJ, Roberts TM, Stiles CD. Modulation of a Mr 175,000 c-neu receptor isoform in G8/DHFR cells by serum starvation. J Biol Chem 1990;265:10746-51.
    • (1990) J Biol Chem , vol.265 , pp. 10746-10751
    • Epstein, R.J.1    Druker, B.J.2    Roberts, T.M.3    Stiles, C.D.4
  • 21
    • 0344825125 scopus 로고    scopus 로고
    • Small interfering RNA (siRNA) inhibits the expression of the Her2/neu gene, upregulates HLA class I and induces apoptosis of Her2/neu positive tumor cell lines
    • Choudhury A, Charo J, Parapuram SK, Hunt RC, Hunt DM, Seliger B, Kiessling R. Small interfering RNA (siRNA) inhibits the expression of the Her2/neu gene, upregulates HLA class I and induces apoptosis of Her2/neu positive tumor cell lines. Int J Cancer 2004;108:71-7.
    • (2004) Int J Cancer , vol.108 , pp. 71-77
    • Choudhury, A.1    Charo, J.2    Parapuram, S.K.3    Hunt, R.C.4    Hunt, D.M.5    Seliger, B.6    Kiessling, R.7
  • 22
    • 0030461224 scopus 로고    scopus 로고
    • Loss of heterozygosity in normal tissue adjacent to breast carcinomas
    • Deng G, Lu Y, Zlotnikov G, Thor AD, Smith HS. Loss of heterozygosity in normal tissue adjacent to breast carcinomas. Science 1996;274:2057-9.
    • (1996) Science , vol.274 , pp. 2057-2059
    • Deng, G.1    Lu, Y.2    Zlotnikov, G.3    Thor, A.D.4    Smith, H.S.5
  • 24
    • 0034660866 scopus 로고    scopus 로고
    • A genome-wide map showing common regions of loss of heterozygosity/allelic imbalance in breast cancer
    • Osborne RJ, Hamshere MG. A genome-wide map showing common regions of loss of heterozygosity/allelic imbalance in breast cancer. Cancer Res 2000;60:3706-12.
    • (2000) Cancer Res , vol.60 , pp. 3706-3712
    • Osborne, R.J.1    Hamshere, M.G.2
  • 25
    • 0000943342 scopus 로고
    • Agar suspension culture for the selective assay of cells transformed by polyoma virus
    • Macpherson I, Montagnier L. Agar suspension culture for the selective assay of cells transformed by polyoma virus. Virology 1964;23:291-4.
    • (1964) Virology , vol.23 , pp. 291-294
    • Macpherson, I.1    Montagnier, L.2
  • 26
    • 0030936450 scopus 로고    scopus 로고
    • Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies
    • Weaver VM, Petersen OW, Wang F, Larabell CA, Briand P, Damsky C, Bissell MJ. Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J Cell Biol 1997;137:231-45.
    • (1997) J Cell Biol , vol.137 , pp. 231-245
    • Weaver, V.M.1    Petersen, O.W.2    Wang, F.3    Larabell, C.A.4    Briand, P.5    Damsky, C.6    Bissell, M.J.7
  • 28
    • 0035252089 scopus 로고    scopus 로고
    • Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes
    • Romanov SR, Kozakiewicz BK, Holst CR, Stampfer MR, Haupt LM, Tlsty TD. Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes. Nature 2001;409:633-7.
    • (2001) Nature , vol.409 , pp. 633-637
    • Romanov, S.R.1    Kozakiewicz, B.K.2    Holst, C.R.3    Stampfer, M.R.4    Haupt, L.M.5    Tlsty, T.D.6
  • 30
    • 0029002907 scopus 로고
    • Aberrant function of the Ras signal transduction pathway in human breast cancer
    • Clark GJ, Der CJ. Aberrant function of the Ras signal transduction pathway in human breast cancer. Breast Cancer Res Treat 1995;35:133-44.
    • (1995) Breast Cancer Res Treat , vol.35 , pp. 133-144
    • Clark, G.J.1    CJ, D.2
  • 31
    • 0033992633 scopus 로고    scopus 로고
    • Biochemical and clinical implications of the ErbB/HER signaling network of growth factor receptors
    • Klapper LN, Kirschbaum MH, Sela M, Yarden Y. Biochemical and clinical implications of the ErbB/HER signaling network of growth factor receptors. Adv Cancer Res 2000;77:25-79.
    • (2000) Adv Cancer Res , vol.77 , pp. 25-79
    • Klapper, L.N.1    Kirschbaum, M.H.2    Sela, M.3    Yarden, Y.4
  • 33
    • 0032482434 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitors, emodin and its derivative repress HER-2/neu-induced cellular transformation and metastasis-associated properties
    • Zhang L, Lau YK, Xi L, Hong RL, Kim DS, Chen CF, Hortobagyi GN, Chang C, Hung MC. Tyrosine kinase inhibitors, emodin and its derivative repress HER-2/neu-induced cellular transformation and metastasis-associated properties. Oncogene 1998;16:2855-63.
    • (1998) Oncogene , vol.16 , pp. 2855-2863
    • Zhang, L.1    Lau, Y.K.2    Xi, L.3    Hong, R.L.4    Kim, D.S.5    Chen, C.F.6    Hortobagyi, G.N.7    Chang, C.8    Hung, M.C.9
  • 35
    • 0026738947 scopus 로고
    • Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells
    • Petersen OW, Ronnov-Jessen L, Howlett AR, Bissell MJ. Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells. Proc Natl Acad Sci USA 1992;89:9064-8.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 9064-9068
    • Petersen, O.W.1    Ronnov-Jessen, L.2    Howlett, A.R.3    Bissell, M.J.4
  • 36
    • 0034458531 scopus 로고    scopus 로고
    • Culture models of human mammary epithelial cell transformation
    • Stampfer MR, Yaswen P. Culture models of human mammary epithelial cell transformation. J Mammary Gland Biol Neoplasia 2000;5:365-78.
    • (2000) J Mammary Gland Biol Neoplasia , vol.5 , pp. 365-378
    • Stampfer, M.R.1    Yaswen, P.2
  • 37
    • 0027510686 scopus 로고
    • Differential isolation of normal luminal mammary epithelial cells and breast cancer cells from primary and metastatic sites using selective media
    • Ethier SP, Mahacek ML, Gullick WJ, Frank TS, Weber BL. Differential isolation of normal luminal mammary epithelial cells and breast cancer cells from primary and metastatic sites using selective media. Cancer Res 1993;53:627-35.
    • (1993) Cancer Res , vol.53 , pp. 627-635
    • Ethier, S.P.1    Mahacek, M.L.2    Gullick, W.J.3    Frank, T.S.4    Weber, B.L.5
  • 38
    • 0035232203 scopus 로고    scopus 로고
    • Myc and mammary cancer: Myc is a downstream effector of the ErbB2 receptor tyrosine kinase
    • Hynes NE, Lane HA. Myc and mammary cancer: Myc is a downstream effector of the ErbB2 receptor tyrosine kinase. J Mammary Gland Biol Neoplasia 2001;6:141-50.
    • (2001) J Mammary Gland Biol Neoplasia , vol.6 , pp. 141-150
    • Hynes, N.E.1    Lane, H.A.2
  • 40
    • 0027733699 scopus 로고
    • Finite proliferative lifespan in vitro of a human breast cancer cell strain isolated from a metastatic lymph node
    • Mahacek ML, Beer DG, Frank TS, Ethier SP. Finite proliferative lifespan in vitro of a human breast cancer cell strain isolated from a metastatic lymph node. Breast Cancer Res Treat 1993;28:267-76.
    • (1993) Breast Cancer Res Treat , vol.28 , pp. 267-276
    • Mahacek, M.L.1    Beer, D.G.2    Frank, T.S.3    Ethier, S.P.4
  • 42
    • 0037087738 scopus 로고    scopus 로고
    • Isolation, immortalization, and characterization of a human breast epithelial cell line with stem cell properties
    • Gudjonsson T, Villadsen R, Nielsen HL, Ronnov-Jessen L, Bissell MJ, Petersen OW. Isolation, immortalization, and characterization of a human breast epithelial cell line with stem cell properties. Genes Dev 2002;16:693-706.
    • (2002) Genes Dev , vol.16 , pp. 693-706
    • Gudjonsson, T.1    Villadsen, R.2    Nielsen, H.L.3    Ronnov-Jessen, L.4    Bissell, M.J.5    Petersen, O.W.6
  • 45
    • 0032720340 scopus 로고    scopus 로고
    • Recent advances in breast cancer biology
    • Schultz LB, Weber BL. Recent advances in breast cancer biology. Curr Opin Oncol 1999;11:429-34.
    • (1999) Curr Opin Oncol , vol.11 , pp. 429-434
    • Schultz, L.B.1    Weber, B.L.2
  • 46
    • 0037052448 scopus 로고    scopus 로고
    • Stromal effects on mammary gland development and breast cancer
    • Wiseman BS, Werb Z. Stromal effects on mammary gland development and breast cancer. Science 2002;296:1046-9.
    • (2002) Science , vol.296 , pp. 1046-1049
    • Wiseman, B.S.1    Werb, Z.2
  • 47
    • 0035835829 scopus 로고    scopus 로고
    • Heterotypic signaling between epithelial tumor cells and fibroblasts in carcinoma formation
    • Elenbaas B, Weinberg RA. Heterotypic signaling between epithelial tumor cells and fibroblasts in carcinoma formation. Exp Cell Res 2001;264:169-84.
    • (2001) Exp Cell Res , vol.264 , pp. 169-184
    • Elenbaas, B.1    Weinberg, R.A.2
  • 48
    • 0033215242 scopus 로고    scopus 로고
    • Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium
    • Olumi AF, Grossfeld GD, Hayward SW, Carroll PR, Tlsty TD, Cunha GR. Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium. Cancer Res 1999;59:5002-11.
    • (1999) Cancer Res , vol.59 , pp. 5002-5011
    • Olumi, A.F.1    Grossfeld, G.D.2    Hayward, S.W.3    Carroll, P.R.4    Tlsty, T.D.5    Cunha, G.R.6
  • 49
    • 0027482399 scopus 로고
    • Enhancement of tumorigenicity of human breast adenocarcinoma cells in nude mice by matrigel and fibroblasts
    • Noel A, De Pauw-Gillet MC, Purnell G, Nusgens B, Lapiere CM, Foidart JM. Enhancement of tumorigenicity of human breast adenocarcinoma cells in nude mice by matrigel and fibroblasts. Br J Cancer 1993;68:909-15.
    • (1993) Br J Cancer , vol.68 , pp. 909-915
    • Noel, A.1    De Pauw-Gillet, M.C.2    Purnell, G.3    Nusgens, B.4    Lapiere, C.M.5    Foidart, J.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.