Peptides and pseudopeptides incorporating D-Phe-Pro-Arg and Arg-Gly-Asp lead sequences as potential antithrombotic agents

Journal of Peptide Science

Volumn 14, Issue 8, 2008, Pages 946-953

  Ilaš, Janez ^a   Hudecz, Ferenc ^b   Süli Vargha, Helga ^b   Kikelj, Danijel ^a  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

^b EÖTVÖS LORÁND UNIVERSITY   (Hungary)

Author keywords

Dual activity; Fibrinogen receptor antagonists; Peptide conjugate; Peptidomimetic; Thrombin inhibition

Indexed keywords

ANTICOAGULANT AGENT; ARGINYLGLYCYLASPARTIC ACID DERIVATIVE; DEXTRO PHENYLALANYLPROLYLARGININE DERIVATIVE; FIBRINOGEN; FIBRINOGEN RECEPTOR; FIBRINOGEN RECEPTOR ANTAGONIST; HEXAPEPTIDE; OCTAPEPTIDE; PEPTIDE DERIVATIVE; PEPTIDOMIMETIC DERIVATIVE; PSEUDOPEPTIDE; THROMBIN; THROMBIN INHIBITOR; TRIPEPTIDE; TRIPEPTIDE DERIVATIVE;

ARTICLE; BIOASSAY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CONJUGATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; PEPTIDE SYNTHESIS; PHARMACOPHORE; PRIORITY JOURNAL; THROMBOCYTE AGGREGATION INHIBITION; THROMBOCYTE RICH PLASMA;

AMINO ACID SEQUENCE; ANTICOAGULANTS; BINDING SITES; DRUG DESIGN; ENZYME INHIBITORS; FIBRINOGEN; HUMANS; MALE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; OLIGOPEPTIDES; PEPTIDES; PLATELET AGGREGATION; RECEPTORS, FIBRINOGEN; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; THROMBIN;

EID: 50449093297     PISSN: 10752617     EISSN: 10991387     Source Type: Journal    
DOI: 10.1002/psc.1030     Document Type: Article

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