Central mechanisms for the hypertensive effects of preproadrenomedullin- derived peptides in conscious rats

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 274, Issue 5 43-5, 1998, Pages

  Samson, Willis K ^a   Murphy, Tonya C ^a   Resch, Zachary T ^a  

^a UNIVERSITY OF NORTH DAKOTA SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

Adrenomedullin; Central regulation of autonomic function; Hypertension; Proadrenomedullin NH2 terminal 20 peptide

Indexed keywords

ADRENOMEDULLIN; CALCITONIN GENE RELATED PEPTIDE RECEPTOR; PROADRENOMEDULLIN;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ARTICLE; BLOOD PRESSURE MONITORING; ELECTROLYTE BALANCE; FLUID INTAKE; GENETIC TRANSCRIPTION; HEART PROTECTION; HOMEOSTASIS; HYPERTENSION; HYPOTHESIS; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; RAT; SYMPATHETIC TONE;

EID: 0031832088     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1998.274.5.r1505     Document Type: Article

References (18)

1. Allen, M. A., and A. V. Ferguson. In vitro recordings from area postrema neurons demonstrate responsiveness to adrenomedullin. Am. J. Physiol. 270 (Regulatory Integrative Comp. Physiol. 39): R920-R925, 1996.
2. Allen, M. A., P. M. Smith, and A. V. Ferguson. Adrenomedullin microinjection into the area postrema increases blood pressure. Am. J. Physiol. 272 (Regulatory Integrative Comp. Physiol. 41): R1698-R1703, 1997.
3. Feng, C. J., B. Kang, A. D. Kaye, P. J. Kadowitz, and B. D. Nossaman. L-NAME modulates responses to adrenomedullin in hindquarters vascular bed of the rat. Life Sci. 55: 433-438, 1994.
4. Ishimitsu, T., T. Nishikimi, Y. Saito, K. Kitamura, T. Eto, K. Kangawa, H. Matsuo, T. Omae, and H. Matsuoka. Plasma levels of adrenomedullin, a newly identified hypotensive peptide, in patients with hypertension and renal failure. J. Clin. Invest. 94: 2158-2161, 1994.
5. Jougasaki, M., C. M. Wei, L. L. Aarhus, D. M. Heublein, S. M. Sandberg, and J. C. Burnett. Renal localization and actions of adrenomedullin: a natriuretic peptide. Am. J. Physiol. 268 (Renal Fluid Electrolyte Physiol. 37): F657-F663, 1995.
6. Katoh, F., K. Kitamura, H. Niina, R. Yamamoto, H. Washimine, K. Kanagawa, Y. Yamamoto, H. Kobayashi, T. Eto, and A. Wada. Proadrenomedullin N-terminal 20 peptide (PAMP), an endogenous anticholinergic peptide: its exocytotic secretion and inhibition of catecholamine secretion in adrenal medulla. J. Neurochem. 64: 459-461, 1995.
7. Katoh, J., K. Kobayashi, T. Etoh, M. Tanaka, K. Kitamura, T. Imamura, Y. Koiwaya, K. Kangawa, and T. Eto. Plasma adrenomedullin concentration in patients with heart failure. J. Clin. Endocrinol. Metab. 81: 180-183, 1996.
8. Murphy, T. C., and W. K. Samson. The novel vasoactive hormone, adrenomedullin, inhibits water drinking in the rat. Endocrinology 136: 2459-2463, 1995.
9. Parkes, D. G. Cardiovascular actions of adrenomedullin in conscious sheep. Am. J. Physiol. 268 (Heart Circ. Physiol. 37): H2574-H2578, 1995.
10. Samson, W. K., and T. C. Murphy. Adrenomedullin inhibits salt appetite. Endocrinology 138: 613-616, 1997.
11. Samson, W. K., T. C. Murphy, and D. A. Schell. A novel vasoactive peptide, adrenomedullin, inhibits pituitary adrenocorticotropin release. Endocrinology 136: 2349-2352, 1995.
12. Satoh, F., K. Takahashi, O. Murakami, K. Totsune, M. Sone, M. Ohneda, K. Abe, Y. Miura, Y. Hyashi, H. Sasano, and T. Mouri. Adrenomedullin in human brain, adrenal glands and tumor tissues of pheochromocytoma, ganglioneuroblastoma and neuroblastoma. J. Clin. Endocrinol. Metab. 80: 1750-1752, 1995.
13. Schell, D. A., R. C. Vari, and W. K. Samson. Adrenomedullin: a newly discovered hormone controlling fluid and electrolyte homeostasis. Trends Endocrinol. Metab. 7: 7-13, 1996.
14. 2-terminal 20 peptide, a new product of the adrenomedullin gene, inhibits norepinephrine overflow from nerve endings. J. Clin. Invest. 96: 1672-1676, 1995.
15. Szokodi, I., P. Kinnunen, and H. Ruskoaho. Inotropic effect of adrenomedullin in the isolated perfused rat heart. Acta Physiol. Scand. 156: 151-152, 1996.
16. Takahashi, H., T. Watanabe, M. Nishimura, T. Nakanishi, M. Sakamoto, M. Yoshimura, Y. Komiyama, M. Masuda, and T. Murakami. Centrally induced vasopressor and sympathetic responses to a novel endogenous peptide, adrenomedullin, in anesthetized rats. Am. J. Hypertens. 7: 478-482, 1994.
17. Vari, R. C., S. D. Adkins, and W. K. Samson. Renal effects of adrenomedullin in the rat. Proc. Soc. Exp. Biol. Med. 211: 178-183, 1996.
18. Yamaguchi, T., K. Baba, Y. Doi, and K. Yano. Effect of adrenomedullin on aldosterone secretion by dispersed rat adrenal glomerulosa cells. Life Sci. 56: 379-387, 1995.