-
1
-
-
0021269073
-
Regulation of peripheral insulin/glucagon levels by rat liver
-
Balks HJ, Jungermann K. Regulation of peripheral insulin/glucagon levels by rat liver. Eur J Biochem 141: 645-650, 1984.
-
(1984)
Eur J Biochem
, vol.141
, pp. 645-650
-
-
Balks, H.J.1
Jungermann, K.2
-
2
-
-
0017582072
-
Activation of protein kinase and glycogen phosphorylase in isolated rat liver cells by glucagon and catecholamines
-
Birnbaum M, Fain JN. Activation of protein kinase and glycogen phosphorylase in isolated rat liver cells by glucagon and catecholamines. J Biol Chem 252: 528-535, 1977.
-
(1977)
J Biol Chem
, vol.252
, pp. 528-535
-
-
Birnbaum, M.1
Fain, J.N.2
-
3
-
-
30044436829
-
p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis
-
Cao W, Collins QF, Becker TC, Robidoux J, Lupo EG, Xiong Y, Daniel KW, Floering L, Collins S. p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis. J Biol Chem 280: 42731-42737, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 42731-42737
-
-
Cao, W.1
Collins, Q.F.2
Becker, T.C.3
Robidoux, J.4
Lupo, E.G.5
Xiong, Y.6
Daniel, K.W.7
Floering, L.8
Collins, S.9
-
4
-
-
33845919110
-
Glucagon receptor knockout mice are resistant to diet-induced obesity and streptozotocin-mediated beta cell loss and hyperglycaemia
-
Conarello S, Jiang G, Mu J, Li Z, Woods J, Zycband E, Ronan J, Liu F, Roy RS, Zhu L, Charron MJ, Zhang BB. Glucagon receptor knockout mice are resistant to diet-induced obesity and streptozotocin-mediated beta cell loss and hyperglycaemia. Diabetologia 50: 142-150, 2007.
-
(2007)
Diabetologia
, vol.50
, pp. 142-150
-
-
Conarello, S.1
Jiang, G.2
Mu, J.3
Li, Z.4
Woods, J.5
Zycband, E.6
Ronan, J.7
Liu, F.8
Roy, R.S.9
Zhu, L.10
Charron, M.J.11
Zhang, B.B.12
-
5
-
-
18644372367
-
Regulation of myocardial contractility and cell size by distinct PI3KPTEN signaling pathways
-
Crackower MA, Oudit GY, Kozieradzki I, Sarao R, Sun H, Sasaki T, Hirsch E, Suzuki A, Shioi T, Irie-Sasaki J, Sah R, Cheng HY, Rybin VO, Lembo G, Fratta L, Oiveira-dos-Santos AJ, Benovic JL, Kahn CR, Izumo S, Steinberg SF, Wymann MP, Backx PH, Penninger JM. Regulation of myocardial contractility and cell size by distinct PI3KPTEN signaling pathways. Cell 110: 737-749, 2002.
-
(2002)
Cell
, vol.110
, pp. 737-749
-
-
Crackower, M.A.1
Oudit, G.Y.2
Kozieradzki, I.3
Sarao, R.4
Sun, H.5
Sasaki, T.6
Hirsch, E.7
Suzuki, A.8
Shioi, T.9
Irie-Sasaki, J.10
Sah, R.11
Cheng, H.Y.12
Rybin, V.O.13
Lembo, G.14
Fratta, L.15
Oiveira-dos-Santos, A.J.16
Benovic, J.L.17
Kahn, C.R.18
Izumo, S.19
Steinberg, S.F.20
Wymann, M.P.21
Backx, P.H.22
Penninger, J.M.23
more..
-
7
-
-
9944222737
-
Quantitation of the large polypeptide glucagon by protein precipitation and LC/MS
-
Delinsky D, Hill KT, White CA, Bartlett MG. Quantitation of the large polypeptide glucagon by protein precipitation and LC/MS. Biomed Chromatogr 18: 700-705, 2004.
-
(2004)
Biomed Chromatogr
, vol.18
, pp. 700-705
-
-
Delinsky, D.1
Hill, K.T.2
White, C.A.3
Bartlett, M.G.4
-
8
-
-
2342519996
-
Alanine infusion during hypoglycaemia partly supports cognitive performance in healthy human subjects
-
Evans M, Hopkins D, Macdonald IA, Amiel SA. Alanine infusion during hypoglycaemia partly supports cognitive performance in healthy human subjects. Diabet Med 21: 440-446, 2004.
-
(2004)
Diabet Med
, vol.21
, pp. 440-446
-
-
Evans, M.1
Hopkins, D.2
Macdonald, I.A.3
Amiel, S.A.4
-
9
-
-
0015240282
-
Studies on the role of adenosine 3′,5′-monophosphate in the hepatic actions of glucagon and catecholamines
-
Exton J, Robison GA, Sutherland EW, Park CR. Studies on the role of adenosine 3′,5′-monophosphate in the hepatic actions of glucagon and catecholamines. J Biol Chem 246: 6166-6177, 1971.
-
(1971)
J Biol Chem
, vol.246
, pp. 6166-6177
-
-
Exton, J.1
Robison, G.A.2
Sutherland, E.W.3
Park, C.R.4
-
10
-
-
0037417984
-
Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice
-
Gelling R, Du XQ, Dichmann DS, Romer J, Huang H, Cui L, Obici S, Tang B, Holst JJ, Fledelius C, Johansen PB, Rossetti L, Jelicks LA, Serup P, Nishimura E, Charron MJ. Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice. Proc Natl Acad Sci USA 100: 1438-1443, 2003.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1438-1443
-
-
Gelling, R.1
Du, X.Q.2
Dichmann, D.S.3
Romer, J.4
Huang, H.5
Cui, L.6
Obici, S.7
Tang, B.8
Holst, J.J.9
Fledelius, C.10
Johansen, P.B.11
Rossetti, L.12
Jelicks, L.A.13
Serup, P.14
Nishimura, E.15
Charron, M.J.16
-
11
-
-
0019347265
-
Physiology of glucagon
-
Gerich J. Physiology of glucagon. Int Rev Physiol 24: 243-275, 1981.
-
(1981)
Int Rev Physiol
, vol.24
, pp. 243-275
-
-
Gerich, J.1
-
12
-
-
33846856711
-
Alpha-cells of the endocrine pancreas: 35 years of research but the enigma remains
-
Gromada J, Franklin I, Wollheim CB. Alpha-cells of the endocrine pancreas: 35 years of research but the enigma remains. Endocr Rev 28: 84-116, 2007.
-
(2007)
Endocr Rev
, vol.28
, pp. 84-116
-
-
Gromada, J.1
Franklin, I.2
Wollheim, C.B.3
-
13
-
-
0024406131
-
Age-dependent effects of phorbol ester on adenylate cyclase stimulation by glucagon in liver of female rats
-
Hermsdorf T, Dettmer D, Hofmann E. Age-dependent effects of phorbol ester on adenylate cyclase stimulation by glucagon in liver of female rats. Biomed Biochim Acta 48: 255-260, 1989.
-
(1989)
Biomed Biochim Acta
, vol.48
, pp. 255-260
-
-
Hermsdorf, T.1
Dettmer, D.2
Hofmann, E.3
-
14
-
-
0029178019
-
Compartmentalization of cyclic AMP phosphodiesterases, signalling 'crosstalk', desensitization and the phosphorylation of Gi-2 add cell specific personalization to the control of the levels of the second messenger cyclic AMP
-
Houslay M. Compartmentalization of cyclic AMP phosphodiesterases, signalling 'crosstalk', desensitization and the phosphorylation of Gi-2 add cell specific personalization to the control of the levels of the second messenger cyclic AMP. Adv Enzyme Regul 35: 303-338, 1995.
-
(1995)
Adv Enzyme Regul
, vol.35
, pp. 303-338
-
-
Houslay, M.1
-
15
-
-
0032387694
-
Effects of glucagon on glycogenolysis and gluconeogenesis are region-specific in periportal and perivenous hepatocytes
-
Ikezawa Y, Yamatani K, Ogawa A, Ohnuma H, Igarashi M, Daimon M, Manaka H, Sasaki H. Effects of glucagon on glycogenolysis and gluconeogenesis are region-specific in periportal and perivenous hepatocytes. J Lab Clin Med 132: 547-555, 1998.
-
(1998)
J Lab Clin Med
, vol.132
, pp. 547-555
-
-
Ikezawa, Y.1
Yamatani, K.2
Ogawa, A.3
Ohnuma, H.4
Igarashi, M.5
Daimon, M.6
Manaka, H.7
Sasaki, H.8
-
16
-
-
0036084145
-
Effects of recurrent hyperinsulinemia with and without hypoglycemia on counterregulation in diabetic rats
-
Inouye K, Shum K, Chan O, Mathoo J, Matthews SG, Vranic M. Effects of recurrent hyperinsulinemia with and without hypoglycemia on counterregulation in diabetic rats. Am J Physiol Endocrinol Metab 282: E1369-E1379, 2002.
-
(2002)
Am J Physiol Endocrinol Metab
, vol.282
-
-
Inouye, K.1
Shum, K.2
Chan, O.3
Mathoo, J.4
Matthews, S.G.5
Vranic, M.6
-
17
-
-
0021343484
-
Transhepatic glucagon gradients in man: Evidence for glucagon extraction by human liver
-
Jaspan J, Ruddick J, Rayfield E. Transhepatic glucagon gradients in man: evidence for glucagon extraction by human liver. J Clin Endocrinol Metab 58: 287-292, 1984.
-
(1984)
J Clin Endocrinol Metab
, vol.58
, pp. 287-292
-
-
Jaspan, J.1
Ruddick, J.2
Rayfield, E.3
-
18
-
-
0027531638
-
Expression cloning and signaling properties of the rat glucagon receptor
-
Jelinek L, Lok S, Rosenberg GB, Smith RA, Grant FJ, Biggs S, Bensch PA, Kuijper JL, Sheppard PO, Sprecher CA, O'Hara PJ, Foster D, Walker KM, Chen LHJ, McKernan PA, Kindsvogel W. Expression cloning and signaling properties of the rat glucagon receptor. Science 259: 1614-1616, 1993.
-
(1993)
Science
, vol.259
, pp. 1614-1616
-
-
Jelinek, L.1
Lok, S.2
Rosenberg, G.B.3
Smith, R.A.4
Grant, F.J.5
Biggs, S.6
Bensch, P.A.7
Kuijper, J.L.8
Sheppard, P.O.9
Sprecher, C.A.10
O'Hara, P.J.11
Foster, D.12
Walker, K.M.13
Chen, L.H.J.14
McKernan, P.A.15
Kindsvogel, W.16
-
20
-
-
57049128398
-
Metabolic effects of glucagon in the perfused rat heart
-
Kreisberg R, Williamson JR. Metabolic effects of glucagon in the perfused rat heart. Am J Physiol 207: 721-727, 1964.
-
(1964)
Am J Physiol
, vol.207
, pp. 721-727
-
-
Kreisberg, R.1
Williamson, J.R.2
-
21
-
-
0029808270
-
Signaling pathway involved in the activation of heart 6-phosphofructo-2-kinase by insulin
-
Lefebvre V, Mechin MC, Louckx MP, Rider MH, Hue L. Signaling pathway involved in the activation of heart 6-phosphofructo-2-kinase by insulin. J Biol Chem 271: 22289-22292, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 22289-22292
-
-
Lefebvre, V.1
Mechin, M.C.2
Louckx, M.P.3
Rider, M.H.4
Hue, L.5
-
22
-
-
33644987298
-
Glucagon receptor-mediated extracellular signal-regulated kinase 1/2 phosphorylation in rat mesangial cells: Role of protein kinase A and phospholipase C
-
Li X, Carretero OA, Shao Y, Zhuo JL. Glucagon receptor-mediated extracellular signal-regulated kinase 1/2 phosphorylation in rat mesangial cells: role of protein kinase A and phospholipase C. Hypertension 47: 580-585, 2006.
-
(2006)
Hypertension
, vol.47
, pp. 580-585
-
-
Li, X.1
Carretero, O.A.2
Shao, Y.3
Zhuo, J.L.4
-
23
-
-
0021961911
-
Glucagon receptor of human liver. Studies of its molecular weight and binding properties, and its ability to activate hepatic adenylyl cyclase of non-obese and obese subjects
-
Livingston J, Einarsson K, Backman L, Ewerth S, Arner P. Glucagon receptor of human liver. Studies of its molecular weight and binding properties, and its ability to activate hepatic adenylyl cyclase of non-obese and obese subjects. J Clin Invest 75: 397-403, 1985.
-
(1985)
J Clin Invest
, vol.75
, pp. 397-403
-
-
Livingston, J.1
Einarsson, K.2
Backman, L.3
Ewerth, S.4
Arner, P.5
-
24
-
-
0014899070
-
Glucagon levels and metabolic effects in fasting man
-
Marliss E, Aoki TT, Unger RH, Soeldner JS, Cahill GF Jr. Glucagon levels and metabolic effects in fasting man. J Clin Invest 49: 2256-2270, 1970.
-
(1970)
J Clin Invest
, vol.49
, pp. 2256-2270
-
-
Marliss, E.1
Aoki, T.T.2
Unger, R.H.3
Soeldner, J.S.4
Cahill Jr., G.F.5
-
25
-
-
11144253483
-
Convergent signal transduction pathways controlling cardiomyocyte survival and function: The role of PI 3-kinase and Akt
-
Matsui T, Rosenzweig A. Convergent signal transduction pathways controlling cardiomyocyte survival and function: the role of PI 3-kinase and Akt. J Mol Cell Cardiol 38: 63-71, 2005.
-
(2005)
J Mol Cell Cardiol
, vol.38
, pp. 63-71
-
-
Matsui, T.1
Rosenzweig, A.2
-
26
-
-
0025270818
-
Glucagon stimulates the cardiac Ca2+ current by activation of adenylyl cyclase and inhibition of phosphodiesterase
-
Méry P, Brechler V, Pavoine C, Pecke F. Glucagon stimulates the cardiac Ca2+ current by activation of adenylyl cyclase and inhibition of phosphodiesterase. Nature 345: 158-161, 1990.
-
(1990)
Nature
, vol.345
, pp. 158-161
-
-
Méry, P.1
Brechler, V.2
Pavoine, C.3
Pecke, F.4
-
27
-
-
0014511498
-
Effect of glucagon on rat heart adenyl cyclase
-
Murad F, Vaughan M. Effect of glucagon on rat heart adenyl cyclase. Biochem Pharmacol 18: 1053-1059, 1969.
-
(1969)
Biochem Pharmacol
, vol.18
, pp. 1053-1059
-
-
Murad, F.1
Vaughan, M.2
-
28
-
-
0023127427
-
The rapid desensitization of glucagon-stimulated adenylate cyclase is a cyclic AMP-independent process that can be mimicked by hormones which stimulate inositol phospholipid metabolism
-
Murphy G, Hruby VJ, Trivedi D, Wakelam MJ, Houslay MD. The rapid desensitization of glucagon-stimulated adenylate cyclase is a cyclic AMP-independent process that can be mimicked by hormones which stimulate inositol phospholipid metabolism. Biochem J 243: 39-46, 1987.
-
(1987)
Biochem J
, vol.243
, pp. 39-46
-
-
Murphy, G.1
Hruby, V.J.2
Trivedi, D.3
Wakelam, M.J.4
Houslay, M.D.5
-
29
-
-
3242698804
-
The role of phosphoinositide-3 kinase and PTEN in cardiovascular physiology and disease
-
Oudit G, Sun H, Kerfant BG, Crackower MA, Penninger JM, Backx PH. The role of phosphoinositide-3 kinase and PTEN in cardiovascular physiology and disease. J Mol Cell Cardiol 37: 449-471, 2004.
-
(2004)
J Mol Cell Cardiol
, vol.37
, pp. 449-471
-
-
Oudit, G.1
Sun, H.2
Kerfant, B.G.3
Crackower, M.A.4
Penninger, J.M.5
Backx, P.H.6
-
30
-
-
0036296165
-
Glycemic control in mice with targeted disruption of the glucagon receptor gene
-
Parker J, Andrews KM, Allen MR, Stock JL, McNeish JD. Glycemic control in mice with targeted disruption of the glucagon receptor gene. Biochem Biophys Res Commun 290: 839-843, 2002.
-
(2002)
Biochem Biophys Res Commun
, vol.290
, pp. 839-843
-
-
Parker, J.1
Andrews, K.M.2
Allen, M.R.3
Stock, J.L.4
McNeish, J.D.5
-
31
-
-
23044517378
-
Maintenance of the postabsorptive plasma glucose concentration: Insulin or insulin plus glucagon?
-
Raju B, Cryer PE. Maintenance of the postabsorptive plasma glucose concentration: insulin or insulin plus glucagon? Am J Physiol Endocrinol Metab 289: E181-E186, 2005.
-
(2005)
Am J Physiol Endocrinol Metab
, vol.289
-
-
Raju, B.1
Cryer, P.E.2
-
32
-
-
84965091312
-
The relationship of epinephrine and glucagon to liver phosphorylase. IV. Effect of epinephrine and glucagon on the reactivation of phosphorylase in liver homogenates
-
Rall T, Sutherland EW, Berthet J. The relationship of epinephrine and glucagon to liver phosphorylase. IV. Effect of epinephrine and glucagon on the reactivation of phosphorylase in liver homogenates. J Biol Chem 224: 463-475, 1957.
-
(1957)
J Biol Chem
, vol.224
, pp. 463-475
-
-
Rall, T.1
Sutherland, E.W.2
Berthet, J.3
-
33
-
-
0020074103
-
Cyclic AMP-dependent and cyclic AMP-independent antagonism of insulin activation of cardiac glycogen synthase
-
Ramachandran C, Angelos KL, Walsh DA. Cyclic AMP-dependent and cyclic AMP-independent antagonism of insulin activation of cardiac glycogen synthase. J Biol Chem 257: 1448-1457, 1982.
-
(1982)
J Biol Chem
, vol.257
, pp. 1448-1457
-
-
Ramachandran, C.1
Angelos, K.L.2
Walsh, D.A.3
-
34
-
-
0035201478
-
Insulin-like effects of a physiologic concentration of carnitine on cardiac metabolism
-
Rodgers R, Christe ME, Tremblay GC, Babson JR, Daniels T. Insulin-like effects of a physiologic concentration of carnitine on cardiac metabolism. Mol Cell Biochem 226: 97-105, 2001.
-
(2001)
Mol Cell Biochem
, vol.226
, pp. 97-105
-
-
Rodgers, R.1
Christe, M.E.2
Tremblay, G.C.3
Babson, J.R.4
Daniels, T.5
-
35
-
-
0019523661
-
Responses of rat and guinea pig hearts to glucagon. Lack of evidence for a dissociation between changes in myocardial cyclic 35-adenosine monophosphate and contractility
-
Rodgers R, MacLeod KM, McNeill JH. Responses of rat and guinea pig hearts to glucagon. Lack of evidence for a dissociation between changes in myocardial cyclic 35-adenosine monophosphate and contractility. Circ Res 49: 216-225, 1981.
-
(1981)
Circ Res
, vol.49
, pp. 216-225
-
-
Rodgers, R.1
MacLeod, K.M.2
McNeill, J.H.3
-
36
-
-
1442350003
-
The effects of dehydroepiandrosterone sulfate on counterregulatory responses during repeated hypoglycemia in conscious normal rats
-
Sandoval D, Ping L, Neill RA, Morrey S, Davis SN. The effects of dehydroepiandrosterone sulfate on counterregulatory responses during repeated hypoglycemia in conscious normal rats. Diabetes 53: 679-686, 2004.
-
(2004)
Diabetes
, vol.53
, pp. 679-686
-
-
Sandoval, D.1
Ping, L.2
Neill, R.A.3
Morrey, S.4
Davis, S.N.5
-
37
-
-
33845522289
-
Glucagon receptor knockout mice display increased insulin sensitivity and impaired beta-cell function
-
Sørensen H, Winzell MS, Brand CL, Fosgerau K, Gelling RW, Nishimura E, Ahren B. Glucagon receptor knockout mice display increased insulin sensitivity and impaired beta-cell function. Diabetes 55: 3463-3469, 2006.
-
(2006)
Diabetes
, vol.55
, pp. 3463-3469
-
-
Sørensen, H.1
Winzell, M.S.2
Brand, C.L.3
Fosgerau, K.4
Gelling, R.W.5
Nishimura, E.6
Ahren, B.7
-
38
-
-
0031193750
-
Molecular mechanisms underlying the long-term impact of dietary fat to increase cardiac pyruvate dehydrogenase kinase: Regulation by insulin, cyclic AMP and pyruvate
-
Sugden M, Orfali KA, Fryer LG, Holness MJ, Priestman DA. Molecular mechanisms underlying the long-term impact of dietary fat to increase cardiac pyruvate dehydrogenase kinase: regulation by insulin, cyclic AMP and pyruvate. J Mol Cell Cardiol 29: 1867-1875, 1997.
-
(1997)
J Mol Cell Cardiol
, vol.29
, pp. 1867-1875
-
-
Sugden, M.1
Orfali, K.A.2
Fryer, L.G.3
Holness, M.J.4
Priestman, D.A.5
-
39
-
-
0015493877
-
Studies on the mechanism of hormone action
-
Sutherland E. Studies on the mechanism of hormone action. Science 177: 401-408, 1972.
-
(1972)
Science
, vol.177
, pp. 401-408
-
-
Sutherland, E.1
-
40
-
-
0030992837
-
Signalling through the lipid products of phosphoinositide-3-OH kinase
-
Toker A, Cantley LC. Signalling through the lipid products of phosphoinositide-3-OH kinase. Nature 387: 673-676, 1997.
-
(1997)
Nature
, vol.387
, pp. 673-676
-
-
Toker, A.1
Cantley, L.C.2
-
41
-
-
0024842752
-
Biological activities of des-His1[Glu9]glucagon amide, a glucagon antagonist
-
Unson CG, Gurzenda EM, Merrifield RB. Biological activities of des-His1[Glu9]glucagon amide, a glucagon antagonist. Peptides 10: 1171-1177, 1989.
-
(1989)
Peptides
, vol.10
, pp. 1171-1177
-
-
Unson, C.G.1
Gurzenda, E.M.2
Merrifield, R.B.3
-
42
-
-
0023041534
-
Activation of two signal-transduction systems in hepatocytes by glucagon
-
Wakelam M, Murphy GJ, Hruby VJ, Houslay MD. Activation of two signal-transduction systems in hepatocytes by glucagon. Nature 323: 68-71, 1986.
-
(1986)
Nature
, vol.323
, pp. 68-71
-
-
Wakelam, M.1
Murphy, G.J.2
Hruby, V.J.3
Houslay, M.D.4
-
43
-
-
0034646633
-
Leptin induces insulin-like signaling that antagonizes cAMP elevation by glucagon in hepatocytes
-
Zhao A, Shinohara MM, Huang D, Shimizu M, Eldar-Finkelman H, Krebs EG, Beavo JA, Bornfeldt KE. Leptin induces insulin-like signaling that antagonizes cAMP elevation by glucagon in hepatocytes. J Biol Chem 275: 11348-11354, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 11348-11354
-
-
Zhao, A.1
Shinohara, M.M.2
Huang, D.3
Shimizu, M.4
Eldar-Finkelman, H.5
Krebs, E.G.6
Beavo, J.A.7
Bornfeldt, K.E.8
|