Quantitation of the large polypeptide glucagon by protein precipitation and LC/MS

Biomedical Chromatography

Volumn 18, Issue 9, 2004, Pages 700-705

  Delinsky, David C ^a   Hill, Kim T ^a   White, Catherine A ^a   Bartlett, Michael G ^a  

^a UNIVERSITY OF GEORGIA   (United States)

Author keywords

LC MS; Peptide; Polypeptide; Protein precipitation; Quantitation

Indexed keywords

CALIBRATION; PORE SIZE; POSITIVE IONS;

CHARGE STATE; INTERNAL STANDARDS; LC/MS; LINEAR GRADIENTS; LOWER LIMITS OF QUANTITATIONS; MOBILE PHASIS; POSITIVE ION MODE; PROTEIN PRECIPITATION; QUANTITATION; RAT PLASMA;

PEPTIDES;

ACETIC ACID; ACETONITRILE; GLUCAGON; POLYPEPTIDE; TRIFLUOROACETIC ACID; WATER;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CALIBRATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG ELIMINATION; DRUG HALF LIFE; ION MONITORING; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NONHUMAN; PRECIPITATION; PROTEIN ANALYSIS; QUANTITATIVE ANALYSIS; RAT; SENSITIVITY AND SPECIFICITY; STANDARD; VALIDATION PROCESS;

EID: 9944222737     PISSN: 02693879     EISSN: None     Source Type: Journal    
DOI: 10.1002/bmc.380     Document Type: Article

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