-
1
-
-
0037068353
-
DNA methylation in cancer: Too much, but also too little
-
Ehrlich M. DNA methylation in cancer: too much, but also too little. Oncogene 2002;21:5400-13.
-
(2002)
Oncogene
, vol.21
, pp. 5400-5413
-
-
Ehrlich, M.1
-
2
-
-
1042278765
-
The history of cancer epigenetics
-
Feinberg AP, Tycko B. The history of cancer epigenetics. Nat Rev Cancer 2004;4:143-53.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 143-153
-
-
Feinberg, A.P.1
Tycko, B.2
-
3
-
-
33847065486
-
The epigenomics of cancer
-
Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007;128:683-92.
-
(2007)
Cell
, vol.128
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
4
-
-
23144464171
-
Cancer/testis antigens, gametogenesis and cancer
-
Simpson AJ, Caballero OL, Jungbluth A, Chen YT, Old LJ. Cancer/testis antigens, gametogenesis and cancer. Nat Rev Cancer 2005;5:615-25.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 615-625
-
-
Simpson, A.J.1
Caballero, O.L.2
Jungbluth, A.3
Chen, Y.T.4
Old, L.J.5
-
5
-
-
0032694084
-
DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-richpromoter
-
De Smet C, Lurquin C, Lethe B, Martelange V, BoonT. DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-richpromoter. Mol Cell Biol 1999;19:7327-35.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 7327-7335
-
-
De Smet, C.1
Lurquin, C.2
Lethe, B.3
Martelange, V.4
BoonT5
-
6
-
-
0029957792
-
The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation
-
De Smet C, De Backer O, Faraoni I, Lurquin C, Brasseur F, BoonT. The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation. Proc Natl Acad Sci U S A1996;93:7149-53.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 7149-7153
-
-
De Smet, C.1
De Backer, O.2
Faraoni, I.3
Lurquin, C.4
Brasseur, F.5
BoonT6
-
7
-
-
33750584813
-
Epigenetic regulation of X-linked cancer/germline antigen genes by DNMT1 and DNMT3b
-
James SR, Link PA, Karpf AR. Epigenetic regulation of X-linked cancer/germline antigen genes by DNMT1 and DNMT3b. Oncogene 2006;25:6975-85.
-
(2006)
Oncogene
, vol.25
, pp. 6975-6985
-
-
James, S.R.1
Link, P.A.2
Karpf, A.R.3
-
8
-
-
33744507681
-
Transient down-regulation of DNMT1 methyltransferase leads to activation and stable hypomethylation of MAGE-A1 in melanoma cells
-
Loriot A, De Plaen E, BoonT, De Smet C. Transient down-regulation of DNMT1 methyltransferase leads to activation and stable hypomethylation of MAGE-A1 in melanoma cells. J Biol Chem 2006;281:10118-26.
-
(2006)
J Biol Chem
, vol.281
, pp. 10118-10126
-
-
Loriot, A.1
De Plaen, E.2
BoonT, D.3
Smet, C.4
-
9
-
-
33744829728
-
Promoter demethylation and histone acetylation mediate gene expression of MAGE-A1, -A2, -A3, and -A12 in human cancer cells
-
Wischnewski F, Pantel K, Schwarzenbach H. Promoter demethylation and histone acetylation mediate gene expression of MAGE-A1, -A2, -A3, and -A12 in human cancer cells. Mol Cancer Res 2006;4:339-49.
-
(2006)
Mol Cancer Res
, vol.4
, pp. 339-349
-
-
Wischnewski, F.1
Pantel, K.2
Schwarzenbach, H.3
-
10
-
-
34547915603
-
Vaccination with an NY-ESO-1 peptide of HLA class l/ll specific-ities induces integrated humoral and T cell responses in ovarian cancer
-
Odunsi K, Qian F, Matsuzaki J, et al. Vaccination with an NY-ESO-1 peptide of HLA class l/ll specific-ities induces integrated humoral and T cell responses in ovarian cancer. Proc Natl Acad Sci U S A 2007; 104:12837-42.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 12837-12842
-
-
Odunsi, K.1
Qian, F.2
Matsuzaki, J.3
-
11
-
-
10844289762
-
Intratumor heterogeneity of cancer/testis antigens expression in human cutaneous melanoma is methylation-regulated and functionally reverted by 5-aza-2'-deoxycytidine
-
Sigalotti L, Fratta E, Coral S, et al. Intratumor heterogeneity of cancer/testis antigens expression in human cutaneous melanoma is methylation-regulated and functionally reverted by 5-aza-2'-deoxycytidine. Cancer Res 2004;64:9167-71
-
(2004)
Cancer Res
, vol.64
, pp. 9167-9171
-
-
Sigalotti, L.1
Fratta, E.2
Coral, S.3
-
12
-
-
0035875049
-
Excessive CpG island hypermethylation in cancer cell lines versus primary human malignancies
-
Smiraglia DJ, Rush LJ, Fruhwald MC, et al. Excessive CpG island hypermethylation in cancer cell lines versus primary human malignancies. Hum Mol Genet 2001;10:1413-9.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 1413-1419
-
-
Smiraglia, D.J.1
Rush, L.J.2
Fruhwald, M.C.3
-
14
-
-
0036813331
-
Cancer/testis antigens: An expanding family of targets for cancer immunotherapy
-
Scanlan MJ, GureAO, Jungbluth AA, Old LJ, Chen YT. Cancer/testis antigens: an expanding family of targets for cancer immunotherapy. Immunol Rev 2002; 188:22-32.
-
(2002)
Immunol Rev
, vol.188
, pp. 22-32
-
-
Scanlan, M.J.1
Gure, A.O.2
Jungbluth, A.A.3
Old, L.J.4
Chen, Y.T.5
-
15
-
-
0141507936
-
NY-ESO-1 and LAGE-1 cancer-testis antigens are potential targets for immunotherapy in epithelial ovarian cancer
-
Odunsi K, Jungbluth AA, Stockert E, et al. NY-ESO-1 and LAGE-1 cancer-testis antigens are potential targets for immunotherapy in epithelial ovarian cancer. Cancer Res 2003;63:6076 - 83.
-
(2003)
Cancer Res
, vol.63
, pp. 6076-6083
-
-
Odunsi, K.1
Jungbluth, A.A.2
Stockert, E.3
-
16
-
-
0038678777
-
Sensitive and quantitative universal Pyrosequencing methylation analysis of CpG sites
-
Colella S, Shen L, Baggerly KA, Issa JP, Kr -he R. Sensitive and quantitative universal Pyrosequencing methylation analysis of CpG sites. Biotechniques 2003;35:146-50.
-
(2003)
Biotechniques
, vol.35
, pp. 146-150
-
-
Colella, S.1
Shen, L.2
Baggerly, K.A.3
Issa, J.P.4
Kr5
he, R.6
-
17
-
-
12244279345
-
Specific method for the determination of genomic DNA methylation by liquid chromatography-electrospray ionization tandem mass spectrometry
-
Song L, James SR, Kazim L, Karpf AR. Specific method for the determination of genomic DNA methylation by liquid chromatography-electrospray ionization tandem mass spectrometry. Anal Chem 2005; 77:504-10.
-
(2005)
Anal Chem
, vol.77
, pp. 504-510
-
-
Song, L.1
James, S.R.2
Kazim, L.3
Karpf, A.R.4
-
18
-
-
3042822370
-
DNA hypomethylation and ovarian cancer biology
-
18
-
18.Widschwendter M, Jiang G, Woods C, et al. DNA hypomethylation and ovarian cancer biology. Cancer Res 2004:64:4472-80.
-
(2004)
Cancer Res
, vol.64
, pp. 4472-4480
-
-
Widschwendter, M.1
Jiang, G.2
Woods, C.3
-
19
-
-
0033008444
-
-
Lee L, Wang RF.Wang X, et al. NY-ESO-1 may be a potential target for lung cancer immunotherapy. Cancer J Sci Am 1999;5:20-5.
-
Lee L, Wang RF.Wang X, et al. NY-ESO-1 may be a potential target for lung cancer immunotherapy. Cancer J Sci Am 1999;5:20-5.
-
-
-
-
20
-
-
1642454589
-
Limited gene activation in tumor and normal epithelial cells treated with the DNA methyl- transferase inhibitor 5-aza-2'-deoxycytidine
-
Karpf AR, Lasek AW, RirieTO, Hanks AN, Grossman D, Jones DA. Limited gene activation in tumor and normal epithelial cells treated with the DNA methyl- transferase inhibitor 5-aza-2'-deoxycytidine. Mol Pharmacol 2004;65:18-27.
-
(2004)
Mol Pharmacol
, vol.65
, pp. 18-27
-
-
Karpf, A.R.1
Lasek, A.W.2
Ririe, T.O.3
Hanks, A.N.4
Grossman, D.5
Jones, D.A.6
-
21
-
-
0029118803
-
Involvement of two Ets binding sites in the transcriptional activation of the MAGE1 gene
-
De Smet C, Courtois SJ, Faraoni I, etal. Involvement of two Ets binding sites in the transcriptional activation of the MAGE1 gene. Immunogenetics 1995:42: 282-90.
-
(1995)
Immunogenetics
, vol.42
, pp. 282-290
-
-
De Smet, C.1
Courtois, S.J.2
Faraoni, I.3
-
22
-
-
34347344986
-
Schrump DS. Dynamic transcriptional regulatory complexes including BORIS, CTCF and Sp1 modulate NY-ESO-1 expression in lung cancer cells
-
KangY, Hong JA, Chen GA, Nguyen DM. Schrump DS. Dynamic transcriptional regulatory complexes including BORIS, CTCF and Sp1 modulate NY-ESO-1 expression in lung cancer cells. Oncogene 2007;26: 4394-403.
-
(2007)
Oncogene
, vol.26
, pp. 4394-4403
-
-
Kang, Y.1
Hong, J.A.2
Chen, G.A.3
Nguyen, D.M.4
-
23
-
-
0032521402
-
The role of DNA methylation in expression of the p19/p16 locus in human bladder cancer cell lines
-
Gonzalgo ML, Hayashida T, Bender CM, et al. The role of DNA methylation in expression of the p19/p16 locus in human bladder cancer cell lines. Cancer Res 1998:58:1245-52.
-
(1998)
Cancer Res
, vol.58
, pp. 1245-1252
-
-
Gonzalgo, M.L.1
Hayashida, T.2
Bender, C.M.3
-
24
-
-
34447130813
-
Frequent intra-tumoural heterogeneity of promoter hypermethylation in malignant melanoma
-
Rastetter M, Schagdarsurengin U, Lahtz C, et al. Frequent intra-tumoural heterogeneity of promoter hypermethylation in malignant melanoma. Histol Histopathol 2007;22:1005-15.
-
(2007)
Histol Histopathol
, vol.22
, pp. 1005-1015
-
-
Rastetter, M.1
Schagdarsurengin, U.2
Lahtz, C.3
-
25
-
-
34547935029
-
Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins
-
Ostler KR, Davis EM, Payne SL, et al. Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins. Oncogene 2007:26:5553 - 63
-
(2007)
Oncogene
, vol.26
, pp. 5553-5563
-
-
Ostler, K.R.1
Davis, E.M.2
Payne, S.L.3
-
26
-
-
38349023135
-
Expression of BORIS in melanoma: Lack of association with MAGE-A1 activation
-
Kholmanskikh 0, Loriot A, Brasseur F, De Plaen E, De Smet C. Expression of BORIS in melanoma: lack of association with MAGE-A1 activation. Int J Cancer 2008:122:777-84.
-
(2008)
Int J Cancer
, vol.122
, pp. 777-784
-
-
Kholmanskikh 01
Loriot, A.2
Brasseur, F.3
De Plaen, E.4
De Smet, C.5
-
27
-
-
24744440159
-
Conditional expression of the CTCF-paralogous transcriptional factor BORIS in normal cells results in demethylation and derepression of MAGE-A1 and reactivation of other cancer-testis genes
-
Vatolin S, Abdullaev Z, Pack SD, et al. Conditional expression of the CTCF-paralogous transcriptional factor BORIS in normal cells results in demethylation and derepression of MAGE-A1 and reactivation of other cancer-testis genes Cancer Res 2005:65: 7751 -62.
-
(2005)
Cancer Res
, vol.65
, pp. 7751-7762
-
-
Vatolin, S.1
Abdullaev, Z.2
Pack, S.D.3
-
28
-
-
24744448032
-
Reciprocal binding of CTCF and BORIS to the NY-ESO-1 promoter coincides with derepression of this cancer- testis gene in lung cancer cells
-
Hong JA, Kang Y, Abdullaev Z. et al. Reciprocal binding of CTCF and BORIS to the NY-ESO-1 promoter coincides with derepression of this cancer- testis gene in lung cancer cells. Cancer Res 2005; 65:7763-74.
-
(2005)
Cancer Res
, vol.65
, pp. 7763-7774
-
-
Hong, J.A.1
Kang, Y.2
Abdullaev, Z.3
-
29
-
-
38149047500
-
DNA methylation-dependent regulation of BORIS/CTCFL expression in ovarian cancer
-
Woloszynska-Read A, James SR, Link PA, Yu J, Odunsi K, Karpf AR. DNA methylation-dependent regulation of BORIS/CTCFL expression in ovarian cancer. Cancer Immun 2007:7:21.
-
(2007)
Cancer Immun
, vol.7
, pp. 21
-
-
Woloszynska-Read, A.1
James, S.R.2
Link, P.A.3
Yu, J.4
Odunsi, K.5
Karpf, A.R.6
-
30
-
-
33750326078
-
-
Schrump DS, Fischette MR. Nguyen DM. et al Phase I study of decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura. Clin Cancer Res 2006:12: 5777-85.
-
Schrump DS, Fischette MR. Nguyen DM. et al Phase I study of decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura. Clin Cancer Res 2006:12: 5777-85.
-
-
-
-
31
-
-
0242539831
-
Epigenetic targets for immune intervention in human malignancies
-
Maio M, Coral S, Fratta E, Altomonte M, Sigalotti L. Epigenetic targets for immune intervention in human malignancies Oncogene 2003:22:6484-8
-
(2003)
Oncogene
, vol.22
, pp. 6484-6488
-
-
Maio, M.1
Coral, S.2
Fratta, E.3
Altomonte, M.4
Sigalotti, L.5
-
32
-
-
34250634403
-
A potential role for epigenetic modulatory drugs in the enhancement of cancer/germ-line antigen vaccine efficacy
-
Karpf AR. A potential role for epigenetic modulatory drugs in the enhancement of cancer/germ-line antigen vaccine efficacy. Epigenetics 2006:1 116 - 20
-
(2006)
Epigenetics
, vol.1
, pp. 116-120
-
-
Karpf, A.R.1
|