ALKYLATION;
ARTICLE;
BINDING AFFINITY;
DRUG BINDING;
DRUG DESIGN;
DRUG HYDROXYLATION;
DRUG RECEPTOR BINDING;
DRUG SUBSTITUTION;
DRUG SYNTHESIS;
HUMAN;
HUMAN CELL;
HYDROGENATION;
SWERN OXIDATION;
ANIMAL;
CHEMICAL STRUCTURE;
CHEMISTRY;
COMPARATIVE STUDY;
MASS SPECTROMETRY;
METHODOLOGY;
NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;
PROTEIN BINDING;
SENSITIVITY AND SPECIFICITY;
STEREOISOMERISM;
STRUCTURE ACTIVITY RELATION;
SYNTHESIS;
ANIMALS;
ESTRADIOL;
ETHERS;
HEXANES;
HUMANS;
MAGNETIC RESONANCE SPECTROSCOPY;
MASS SPECTROMETRY;
MOLECULAR STRUCTURE;
PROTEIN BINDING;
RECEPTORS, ESTROGEN;
RECOMBINANT PROTEINS;
SENSITIVITY AND SPECIFICITY;
SERUM ALBUMIN, BOVINE;
STEREOISOMERISM;
STRUCTURE-ACTIVITY RELATIONSHIP;
Third annual William L. McGuire Memorial Lecture. Studies on the estrogen receptor in breast cancer-20 years as a target for the treatment and prevention of cancer
Jordan V.C. Third annual William L. McGuire Memorial Lecture. Studies on the estrogen receptor in breast cancer-20 years as a target for the treatment and prevention of cancer. Breast Cancer Res Treat 36 (1995) 267-285
Fulvestrant: an estrogen receptor antagonist with a novel mechanism of action
Osborne C.K., Wakeling A., and Nicholson R.I. Fulvestrant: an estrogen receptor antagonist with a novel mechanism of action. Br J Cancer 90 Suppl. 1 (2004) S2-S6
A stereoselective synthesis of 7α-(3-carboxypropyl) estradiol from a noncontrolled substance
Adamczyk M., Johnson D., and Reddy E. A stereoselective synthesis of 7α-(3-carboxypropyl) estradiol from a noncontrolled substance. Steroids 62 (1997) 771-775
Synthesis of chimeric 7α-substituted estradiol derivatives linked to cholesterol and cholesterylamine
Hussey S.L., He E., and Peterson B.R. Synthesis of chimeric 7α-substituted estradiol derivatives linked to cholesterol and cholesterylamine. Org Lett 4 (2002) 415-418
Synthesis and binding affinities of novel re-containing 7α-substituted estradiol complexes: models for breast cancer imaging agents
Skaddan M.B., Wust F.R., and Katzenellenbogen J.A. Synthesis and binding affinities of novel re-containing 7α-substituted estradiol complexes: models for breast cancer imaging agents. J Org Chem 64 (1999) 8108-8121
Synthesis of 16α-fluoro ICI, 182,780 derivatives: powerful antiestrogens to image estrogen receptor densities in breast cancer by positron emission tomography
Seimbille Y., Benard F., and van Lier J.E. Synthesis of 16α-fluoro ICI, 182,780 derivatives: powerful antiestrogens to image estrogen receptor densities in breast cancer by positron emission tomography. J Chem Soc, Perkin Trans 1 (2002) 2275-2281
A rationally designed genotoxin that selectively destroys estrogen receptor-positive breast cancer cells
Mitra K., Marquis J.C., Hillier S.M., Rye P.T., Zayas B., Lee A.S., et al. A rationally designed genotoxin that selectively destroys estrogen receptor-positive breast cancer cells. J Am Chem Soc 124 (2002) 1862-1863
Synthesis of a β-estradiol-biotin chimera that potently heterodimerizes estrogen receptor and strepavidin proteins in a yeast three-hybrid system
Hussey S.L., Muddana S.S., and Peterson B.R. Synthesis of a β-estradiol-biotin chimera that potently heterodimerizes estrogen receptor and strepavidin proteins in a yeast three-hybrid system. J Am Chem Soc 125 (2003) 3692-3693
Characterization of the NADPH-dependent metabolism of 17β-estradiol to multiple metabolites by human liver microsomes and selectively expressed human cytochrome P450 3A4 and 3A5
Lee A.J., Kosh J.W., Conney A.H., and Zhu B.T. Characterization of the NADPH-dependent metabolism of 17β-estradiol to multiple metabolites by human liver microsomes and selectively expressed human cytochrome P450 3A4 and 3A5. J Pharmacol Exp Ther 298 (2001) 420-432
Concentration-dependent mitogenic and antiproliferative actions of 2-methoxyestradiol in estrogen receptor-positive human breast cancer cells
Liu Z.J., and Zhu B.T. Concentration-dependent mitogenic and antiproliferative actions of 2-methoxyestradiol in estrogen receptor-positive human breast cancer cells. J Steroid Biochem Mol Biol 88 (2004) 265-275
Fluorine- and trifluoromethyl-substituted toluenes: site selective metalation of aromatic or benzylic positions
Takagishi S., and Schlosser M. Fluorine- and trifluoromethyl-substituted toluenes: site selective metalation of aromatic or benzylic positions. Synlett (1991) 119-121
6-Oxoestradiols from estradiols: exploiting site selective metalation of aralkyl systems with superbases
Tedesco R., Fiaschi R., and Napolitano E. 6-Oxoestradiols from estradiols: exploiting site selective metalation of aralkyl systems with superbases. Synthesis (1995) 1493-1495
Synthesis and mechanism of hydrolysis of estrogen 6-sulfates: model compounds for demonstrating the carcinogenesis of estrogen
Takagi H., Komatsu K., and Yoshizawa I. Synthesis and mechanism of hydrolysis of estrogen 6-sulfates: model compounds for demonstrating the carcinogenesis of estrogen. Steroids 56 (1991) 173-179
Oxidation of long-chain and related alcohols to carbonyls by dimethyl sulfoxide "activated" by oxalyl chloride
Mancuso A.J., Huang S.L., and Swern D. Oxidation of long-chain and related alcohols to carbonyls by dimethyl sulfoxide "activated" by oxalyl chloride. J Org Chem 43 (1978) 2480-2482
New biospecific adsorbents for the purification of estradiol receptor
Bucourt R., Vignau M., Torelli V., Richard-Foy H., Geynet C., Secco-Millet C., et al. New biospecific adsorbents for the purification of estradiol receptor. J Biol Chem 253 (1978) 8821-8828
An expeditious route to 7α-substituted estradiol derivatives
Tedesco R., Katzenellenbogen J.A., and Napolitano E. An expeditious route to 7α-substituted estradiol derivatives. Tetrahedron Lett 38 (1997) 7997-8000
A simple and convenient one-step method for the reductive deoxygenation of aryl ketones to hydrocarbons
Srikrishana A., Sattigeri J.A., Viswajanani R., and Yelamaggad C.V. A simple and convenient one-step method for the reductive deoxygenation of aryl ketones to hydrocarbons. Synlett (1995) 93-94
Hydrogenolysis of carbonyl derivatives as a route to pure aliphatic-aromatic hydrocarbons
Burnham J.W., and Eisenbraun E.J. Hydrogenolysis of carbonyl derivatives as a route to pure aliphatic-aromatic hydrocarbons. J Org Chem 36 (1971) 737-738
