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Volumn 44, Issue 4, 2008, Pages 339-352

Bcl2 mitigates Ca2+ entry and mitochondrial Ca2+ overload through downregulation of L-type Ca2+ channels in PC12 cells

Author keywords

AEQ: Aequorin; Bcl2; Concentration of free Ca2+ ( Ca2+ ); Cytosolic aequorin (cyt_AEQ); Cytosolic concentration of Ca2+ ( Ca2+ c); Mitochondrial concentration of Ca2+ ( Ca2+ m); Mutated aequorin with a mitochondrial targeting signal (mitmut_AEQ); PC12 cells

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; 2 AMINO 6 BROMO 4 (1 CYANO 2 ETHOXY 2 OXOETHYL) 4H CHROMENE 3 CARBOXYLIC ACID ETHYL ESTER; CALCIUM CHANNEL L TYPE; CALCIUM ION; DIGITONIN; IONOMYCIN; POTASSIUM ION; PROTEIN BCL 2; SHORT HAIRPIN RNA; BENZOPYRAN DERIVATIVE; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL STIMULATING AGENT; ETHYL 2-AMINO-6-BROMO-4-(1-CYANO-2-ETHOXY-2-OXOETHYL)-4H-CHROMENE-3-CARBOXYLATE; IONOPHORE; NIMODIPINE; NITRILE; PROTEIN BAD;

EID: 50249107941     PISSN: 01434160     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ceca.2008.01.007     Document Type: Article
Times cited : (24)

References (48)
  • 1
    • 0015880897 scopus 로고
    • The morphology of various types of cell death in prenatal tissues
    • Schweichel J.U., and Merker H.J. The morphology of various types of cell death in prenatal tissues. Teratology 7 (1973) 253-266
    • (1973) Teratology , vol.7 , pp. 253-266
    • Schweichel, J.U.1    Merker, H.J.2
  • 2
    • 0034641936 scopus 로고    scopus 로고
    • Apoptosis in the nervous system
    • Yuan J., and Yankner B.A. Apoptosis in the nervous system. Nature 407 (2000) 802-809
    • (2000) Nature , vol.407 , pp. 802-809
    • Yuan, J.1    Yankner, B.A.2
  • 5
    • 0344688198 scopus 로고    scopus 로고
    • Galantamine prevents apoptosis induced by beta-amyloid and thapsigargin: involvement of nicotinic acetylcholine receptors
    • Arias E., Alés E., Gabilan N.H., et al. Galantamine prevents apoptosis induced by beta-amyloid and thapsigargin: involvement of nicotinic acetylcholine receptors. Neuropharmacology 46 (2004) 103-114
    • (2004) Neuropharmacology , vol.46 , pp. 103-114
    • Arias, E.1    Alés, E.2    Gabilan, N.H.3
  • 6
    • 0035955638 scopus 로고    scopus 로고
    • Calcium entry through L-type calcium channels causes mitochondrial disruption and chromaffin cell death
    • Cano-Abad M.F., Villarroya M., García A.G., and López M.G. Calcium entry through L-type calcium channels causes mitochondrial disruption and chromaffin cell death. J. Biol. Chem. 276 (2001) 39695-39704
    • (2001) J. Biol. Chem. , vol.276 , pp. 39695-39704
    • Cano-Abad, M.F.1    Villarroya, M.2    García, A.G.3    López, M.G.4
  • 7
    • 33751159817 scopus 로고    scopus 로고
    • Depolarization preconditioning produces cytoprotection against veratridine-induced chromaffin cell death
    • Orozco C., García-de-Diego A.M., Arias E., et al. Depolarization preconditioning produces cytoprotection against veratridine-induced chromaffin cell death. Eur. J. Pharmacol. 553 (2006) 28-38
    • (2006) Eur. J. Pharmacol. , vol.553 , pp. 28-38
    • Orozco, C.1    García-de-Diego, A.M.2    Arias, E.3
  • 8
    • 2342564508 scopus 로고    scopus 로고
    • Bcl-2 and calcium: controversy beneath the surface
    • Distelhorst C.W., and Shore G.C. Bcl-2 and calcium: controversy beneath the surface. Oncogene 23 (2004) 2875-2880
    • (2004) Oncogene , vol.23 , pp. 2875-2880
    • Distelhorst, C.W.1    Shore, G.C.2
  • 9
    • 33745958168 scopus 로고    scopus 로고
    • 2+ homeostasis in the endoplasmic reticulum
    • 2+ homeostasis in the endoplasmic reticulum. Cell Death Differ. 13 (2006) 1409-1418
    • (2006) Cell Death Differ. , vol.13 , pp. 1409-1418
    • Pinton, P.1    Rizzuto, R.2
  • 10
    • 0027362667 scopus 로고
    • Investigation of the subcellular distribution of the Bcl2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes
    • Krajewski S., Tanaka S., Takayama S., Schibler M.J., Fenton W., and Reed J.C. Investigation of the subcellular distribution of the Bcl2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes. Cancer Res. 53 (1993) 4701-4714
    • (1993) Cancer Res. , vol.53 , pp. 4701-4714
    • Krajewski, S.1    Tanaka, S.2    Takayama, S.3    Schibler, M.J.4    Fenton, W.5    Reed, J.C.6
  • 12
    • 1842332735 scopus 로고    scopus 로고
    • Bcl-x(L) forms an ion channel in synthetic lipid membranes
    • Minn A.J., Velez P., Schendel S.L.H., et al. Bcl-x(L) forms an ion channel in synthetic lipid membranes. Nature 385 (1997) 353-357
    • (1997) Nature , vol.385 , pp. 353-357
    • Minn, A.J.1    Velez, P.2    Schendel, S.L.H.3
  • 13
    • 0032504242 scopus 로고    scopus 로고
    • Regulation of Bcl-xl channel activity by calcium
    • Lam M., Manjunatha B., Bath B., et al. Regulation of Bcl-xl channel activity by calcium. J. Biol. Chem. 273 (1998) 17307-17310
    • (1998) J. Biol. Chem. , vol.273 , pp. 17307-17310
    • Lam, M.1    Manjunatha, B.2    Bath, B.3
  • 15
    • 0030824575 scopus 로고    scopus 로고
    • Maintenance of calcium homeostasis in the endoplasmic reticulum by Bcl-2
    • He H., Lam M., McCormick T.S., and Distelhorst C.W. Maintenance of calcium homeostasis in the endoplasmic reticulum by Bcl-2. J. Cell Biol. 138 (1997) 1219-1228
    • (1997) J. Cell Biol. , vol.138 , pp. 1219-1228
    • He, H.1    Lam, M.2    McCormick, T.S.3    Distelhorst, C.W.4
  • 17
    • 0035355341 scopus 로고    scopus 로고
    • 2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl2 action
    • 2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl2 action. EMBO J. 20 (2001) 2690-2701
    • (2001) EMBO J. , vol.20 , pp. 2690-2701
    • Pinton, P.1    Ferrari, D.2    Rapizzi, E.3    Di Virgilio, F.4    Pozzan, T.5    Rizzuto, R.6
  • 19
    • 0036491629 scopus 로고    scopus 로고
    • 2+ homeostasis and store-operated channels in prostate cancer cells
    • 2+ homeostasis and store-operated channels in prostate cancer cells. Cancer Cell. 1 (2002) 169-179
    • (2002) Cancer Cell. , vol.1 , pp. 169-179
    • Vanden Abeele, F.1    Skryma, R.2    Shuba, Y.3
  • 20
    • 0032774329 scopus 로고    scopus 로고
    • Bcl2 protects against FCCP-induced apoptosis and mitochondrial membrane potential depolarization in PC12 cells
    • Dispersyn G., Nuydens R., Connors R., Borgers M., and Geerts H. Bcl2 protects against FCCP-induced apoptosis and mitochondrial membrane potential depolarization in PC12 cells. Biochim. Biophys. Acta 1428 (1999) 357-371
    • (1999) Biochim. Biophys. Acta , vol.1428 , pp. 357-371
    • Dispersyn, G.1    Nuydens, R.2    Connors, R.3    Borgers, M.4    Geerts, H.5
  • 21
    • 0034104760 scopus 로고    scopus 로고
    • Bcl2 protects against apoptosis-related microtubule alterations in neuronal cells
    • Nuydens R., Dispersyn G., Van Den Keiboom G., et al. Bcl2 protects against apoptosis-related microtubule alterations in neuronal cells. Apoptosis 5 (2000) 43-51
    • (2000) Apoptosis , vol.5 , pp. 43-51
    • Nuydens, R.1    Dispersyn, G.2    Van Den Keiboom, G.3
  • 26
    • 0024429936 scopus 로고
    • Influence of sodium-calcium exchange on calcium current rundown and the duration of calcium-dependent chloride currents in pituitary cells, studied with whole cell and perforated patch recording
    • Korn S.J., and Horn R. Influence of sodium-calcium exchange on calcium current rundown and the duration of calcium-dependent chloride currents in pituitary cells, studied with whole cell and perforated patch recording. J. Gen. Physiol. 94 (1989) 789-812
    • (1989) J. Gen. Physiol. , vol.94 , pp. 789-812
    • Korn, S.J.1    Horn, R.2
  • 27
    • 0026378835 scopus 로고
    • Long-term monitoring of depolarization induced exocytosis from adrenal medullary chromaffin cells and pancreatic islet B cells using "perforated patch recording"
    • Gillis K.D., Pun R.Y., and Misler S. Long-term monitoring of depolarization induced exocytosis from adrenal medullary chromaffin cells and pancreatic islet B cells using "perforated patch recording". Ann. NY Acad. Sci. 635 (1991) 464-467
    • (1991) Ann. NY Acad. Sci. , vol.635 , pp. 464-467
    • Gillis, K.D.1    Pun, R.Y.2    Misler, S.3
  • 28
    • 0019441262 scopus 로고
    • Improved patch-clamp techniques for high resolution current recording from cells and cell-free membrane patches
    • Hamill O.P., Marty A., Neher E., Sakmann B., and Sigworth F.J. Improved patch-clamp techniques for high resolution current recording from cells and cell-free membrane patches. Pflugers Arch. 391 (1981) 85-100
    • (1981) Pflugers Arch. , vol.391 , pp. 85-100
    • Hamill, O.P.1    Marty, A.2    Neher, E.3    Sakmann, B.4    Sigworth, F.J.5
  • 30
    • 0036190304 scopus 로고    scopus 로고
    • 2+ among cytosol and organella during stimulation of bovine chromaffin cells
    • 2+ among cytosol and organella during stimulation of bovine chromaffin cells. FASEB J. 16 (2002) 343-353
    • (2002) FASEB J. , vol.16 , pp. 343-353
    • Villalobos, C.1    Núnez, L.2    Montero, M.3
  • 32
    • 0028832662 scopus 로고
    • 2+ concentration in the endoplasmic reticulum of intact cells
    • 2+ concentration in the endoplasmic reticulum of intact cells. EMBO J. 14 (1995) 5467-5475
    • (1995) EMBO J. , vol.14 , pp. 5467-5475
    • Montero, M.1    Brini, M.2    Marsault, R.3
  • 33
    • 0034668833 scopus 로고    scopus 로고
    • Mitochondria and calcium: from cell signalling to cell death
    • Duchen M.R. Mitochondria and calcium: from cell signalling to cell death. J. Physiol. 529 (2000) 57-68
    • (2000) J. Physiol. , vol.529 , pp. 57-68
    • Duchen, M.R.1
  • 34
    • 0034668946 scopus 로고    scopus 로고
    • Mitochondria as all-round players of the calcium game
    • Rizzuto R., Bernardi P., and Pozzan T. Mitochondria as all-round players of the calcium game. J. Physiol. 529 (2000) 37-47
    • (2000) J. Physiol. , vol.529 , pp. 37-47
    • Rizzuto, R.1    Bernardi, P.2    Pozzan, T.3
  • 37
    • 0021250015 scopus 로고
    • Dihydropyridine BAY-K-8644 activates chromaffin cell calcium channels
    • García A.G., Sala F., Reig J.A., et al. Dihydropyridine BAY-K-8644 activates chromaffin cell calcium channels. Nature 5963 (1984) 69-71
    • (1984) Nature , vol.5963 , pp. 69-71
    • García, A.G.1    Sala, F.2    Reig, J.A.3
  • 40
    • 0029861623 scopus 로고    scopus 로고
    • Intracellular calcium stores are not required for Bcl-2-mediated protection from apoptosis
    • Reynolds J.E., and Eastman A. Intracellular calcium stores are not required for Bcl-2-mediated protection from apoptosis. J. Biol. Chem. 271 (1996) 27739-27743
    • (1996) J. Biol. Chem. , vol.271 , pp. 27739-27743
    • Reynolds, J.E.1    Eastman, A.2
  • 41
    • 2442508985 scopus 로고    scopus 로고
    • Critical upstream signals of cytochrome C release induced by a novel Bcl-2 inhibitor
    • An J., Chen Y., and Huang Z. Critical upstream signals of cytochrome C release induced by a novel Bcl-2 inhibitor. J. Biol. Chem. 30 (2004) 19133-19140
    • (2004) J. Biol. Chem. , vol.30 , pp. 19133-19140
    • An, J.1    Chen, Y.2    Huang, Z.3
  • 46
    • 0034086946 scopus 로고    scopus 로고
    • A cautionary note on the use of stable transformed cells
    • Blum D., Torch S., Nissou M.F., and Verna J.M. A cautionary note on the use of stable transformed cells. Apoptosis 5 (2000) 115-116
    • (2000) Apoptosis , vol.5 , pp. 115-116
    • Blum, D.1    Torch, S.2    Nissou, M.F.3    Verna, J.M.4
  • 47
    • 0031041089 scopus 로고    scopus 로고
    • Identification of a novel regulatory domain in Bcl-X(L) and Bcl-2
    • Chang B.S., Minn A.J., Muchmore S.W., Fesik S.W., and Thompson C.B. Identification of a novel regulatory domain in Bcl-X(L) and Bcl-2. EMBO J. 16 (1997) 968-977
    • (1997) EMBO J. , vol.16 , pp. 968-977
    • Chang, B.S.1    Minn, A.J.2    Muchmore, S.W.3    Fesik, S.W.4    Thompson, C.B.5
  • 48
    • 0037035807 scopus 로고    scopus 로고
    • 2+ mobilization promotes cytochrome c release during apoptosis
    • 2+ mobilization promotes cytochrome c release during apoptosis. J. Biol. Chem. 277 (2002) 20301-20308
    • (2002) J. Biol. Chem. , vol.277 , pp. 20301-20308
    • Nutt, L.K.J.1    Chandra, A.2    Pataer, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.