Sevoflurane protects against renal ischemia and reperfusion injury in mice via the transforming growth factor-β1 pathway

American Journal of Physiology - Renal Physiology

Volumn 295, Issue 1, 2008, Pages

  Lee, H Thomas ^a,d   Chen, Sean W C ^a   Doetschman, Thomas C ^b   Deng, Chuxia ^c   D'Agati, Vivette D ^a   Kim, Mihwa ^a  

^a Columbia University ^*  (United States)

^b UNIVERSITY OF ARIZONA   (United States)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^d Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Acute renal failure; Inflammation; Necrosis; SMAD3

Indexed keywords

HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHALATION ANESTHETIC AGENT; PENTOBARBITAL; SEVOFLURANE; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; ETHER DERIVATIVE; MESSENGER RNA; SMAD3 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL MOBILITY SHIFT ASSAY; HISTOPATHOLOGY; IN VIVO STUDY; KIDNEY CELL CULTURE; KIDNEY FUNCTION; KIDNEY ISCHEMIA; KIDNEY NECROSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; RENAL PROTECTION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CELL CULTURE; DRUG EFFECT; IMMUNOLOGY; KIDNEY DISEASE; KIDNEY MEDULLA; METABOLISM; PATHOLOGY; PHYSIOLOGY;

ANESTHETICS, INHALATION; ANIMALS; CELLS, CULTURED; KIDNEY DISEASES; KIDNEY MEDULLA; METHYL ETHERS; MICE; NF-KAPPA B; REPERFUSION INJURY; RNA, MESSENGER; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 49949098507     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00577.2007     Document Type: Article

References (30)

1. Bove T, Calabro MG, Landoni G, Aletti G, Marino G, Crescenzi G, Rosica C, Zangrillo A. The incidence and risk of acute renal failure after cardiac surgery. J Cardiothorac Vasc Anesth 18: 442-445, 2004.
2. Chertow GM, Lazarus JM, Christiansen CL, Cook EF, Hammermeister KE, Grover F, Daley J. Preoperative renal risk stratification. Circulation 95: 878-884, 1997.
3. Conlon PJ, Stafford-Smith M, White WD, Newman MF, King S, Winn MP, Landolfo K. Acute renal failure following cardiac surgery. Nephrol Dial Transplant 14: 1158-1162, 1999.
4. Diebold RJ, Eis MJ, Yin M, Ormsby I, Boivin GP, Darrow BJ, Saffitz JE, Doetschman T. Early-onset multifocal inflammation in the transforming growth factor beta 1-null mouse is lymphocyte mediated. Proc Natl Acad Sci USA 92: 12215-12219, 1995.
5. Fadok VA, Bratton DL, Konowal A, Freed PW, Westcott JY, Henson PM. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J Clin Invest 101: 890-898, 1998.
6. Fadok VA, Bratton DL, Rose DM, Pearson A, Ezekewitz RA, Henson PM. A receptor for phosphatidylserine-specific clearance of apoptotic cells. Nature 405: 85-90, 2000.
7. Henson PM, Bratton DL, Fadok VA. The phosphatidylserine receptor: a crucial molecular switch? Nat Rev Mol Cell Biol 2: 627-633, 2001.
8. Hoffmann PR, Kench JA, Vondracek A, Kruk E, Daleke DL, Jordan M, Marrack P, Henson PM, Fadok VA. Interaction between phosphatidylserine and the phosphatidylserine receptor inhibits immune responses in vivo. J Immunol 174: 1393-1404, 2005.
9. Huynh ML, Fadok VA, Henson PM. Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF- beta1 secretion and the resolution of inflammation. J Clin Invest 109: 41-50, 2002.
10. Jones DR, Lee HT. Protecting the kidney during critical illness. Curr Opin Anaesthesiol 20: 106-112, 2007.
11. Lee HT, Gallos G, Nasr SH, Emala CW. A1 adenosine receptor activation inhibits inflammation, necrosis, and apoptosis after renal ischemia-reperfusion injury in mice. J Am Soc Nephrol 15: 102-111, 2004.
12. Lee HT, Kim M, Jan M, Emala CW. Anti-inflammatory and antinecrotic effects of the volatile anesthetic sevoflurane in kidney proximal tubule cells. Am J Physiol Renal Physiol 291: F67-F78, 2006.
13. Lee HT, Kim M, Kim J, Kim N, Emala CW. TGF-β1 release by volatile anesthetics mediates protection against renal proximal tubule cell necrosis. Am J Nephrol 27: 416-424, 2007.
14. Lee HT, Kim M, Kim M, Kim N, Billings IV FT, D'Agati VD, Emala Sr CW. Isoflurane protects against renal ischemia and reperfusion injury and modulates leukocyte infiltration in mice. Am J Physiol Renal Physiol 293: F713-F722, 2007.
15. 1 signaling in renal proximal tubule cells. Am J Physiol Renal Physiol In press.
16. Lee HT, Ota-Setlik A, Fu Y, Nasr SH, Emala CW. Differential protective effects of volatile anesthetics against renal ischemia-reperfusion injury in vivo. Anesthesiology 101: 1313-1324, 2004.
17. Lee HT, Ota-Setlik A, Xu H, D'Agati VD, Jacobson MA, Emala CW. A3 adenosine receptor knockout mice are protected against ischemia- and myoglobinuria-induced renal failure. Am J Physiol Renal Physiol 284: F267-F273, 2003.
18. Lee HT, Xu H, Nasr SH, Schnermann J, Emala CW. A1 adenosine receptor knockout mice exhibit increased renal injury following ischemia and reperfusion. Am J Physiol Renal Physiol 286: F298-F306, 2004.
19. Liu F. Receptor-regulated Smads in TGF-beta signaling. Front Biosci 8: s1280-s1303, 2003.
20. Prud'homme GJ, Piccirillo CA. The inhibitory effects of transforming growth factor-beta-1 (TGF-beta1) in autoimmune diseases. J Autoimmun 14: 23-42, 2000.
21. Ramesh G, Reeves WB. TNF-alpha mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity. J Clin Invest 110: 835-842, 2002.
22. Ramesh G, Reeves WB. Inflammatory cytokines in acute renal failure. Kidney Int Suppl 91: S56-S61, 2004.
23. Roberts AB. TGF-beta signaling from receptors to the nucleus. Microbes Infect 1: 1265-1273, 1999.
24. Shull MM, Doetschman T. Transforming growth factor-beta 1 in reproduction and development. Mol Reprod Dev 39: 239-246, 1994.
25. Star RA. Treatment of acute renal failure. Kidney Int 54: 1817-1831, 1998.
26. Tang IY, Murray PT. Prevention of perioperative acute renal failure: what works? Best Pract Res Clin Anaesthesiol 18: 91-111, 2004.
27. Vinay P, Gougoux A, Lemieux G. Isolation of a pure suspension of rat proximal tubules. Am J Physiol Renal Fluid Electrolyte Physiol 241: F403-F411, 1981.
28. Wang XJ, Han G, Owens P, Siddiqui Y, Li AG. Role of TGF betamediated inflammation in cutaneous wound healing. J Investig Dermatol Symp Proc 11: 112-117, 2006.
29. Xiao YQ, Malcolm K, Worthen GS, Gardai S, Schiemann WP, Fadok VA, Bratton DL, Henson PM. Cross-talk between ERK and p38 MAPK mediates selective suppression of proinflammatory cytokines by transforming growth factor-beta. J Biol Chem 277: 14884-14893, 2002.
30. Yang X, Letterio JJ, Lechleider RJ, Chen L, Hayman R, Gu H, Roberts AB, Deng C. Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta. EMBO J 18: 1280-1291, 1999.