Staphylococcal enterotoxin A acts through nitric oxide synthase mechanisms in human peripheral blood mononuclear cells to stimulate synthesis of pyrogenic cytokines

Infection and Immunity

Volumn 68, Issue 4, 2000, Pages 2003-2008

  Won, Shen Jeu ^a   Huang, Wu Tein ^a   Lai, Yih Shyong ^b   Lin, Mao Tsun ^c  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ANISOMYCIN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 2; INTERLEUKIN 6; NITRIC OXIDE SYNTHASE; STAPHYLOCOCCUS ENTEROTOXIN A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEVER; HUMAN; HUMAN CELL; MONONUCLEAR CELL; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS; SUPERNATANT;

ANIMALS; ANISOMYCIN; ANTI-BACTERIAL AGENTS; ANTI-INFLAMMATORY AGENTS; ANTIBODIES, MONOCLONAL; CYTOKINES; DEXAMETHASONE; ENTEROTOXINS; ENZYME INHIBITORS; GUANIDINES; HUMANS; INTERFERON TYPE II; INTERLEUKIN-1; INTERLEUKIN-2; INTERLEUKIN-6; LEUKOCYTES, MONONUCLEAR; MALE; NITRIC OXIDE SYNTHASE; PYROGENS; RABBITS; TEMPERATURE; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034073440     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.4.2003-2008.2000     Document Type: Article

References (33)

1. Alouf, J. E., H. Knoll, and W. Kohler. 1991. The family of mitogenic, shock-inducing and superantigenic toxins from staphylococci and streptococci, p. 367-414. In J. E. Alouf and J. H. Freer (ed.), Sourcebook of bacterial protein toxins. Academic Press, San Diego, Calif.
2. Baker, P. E., S. Gillis, and K. A. Smith. 1979. Monoclonal cytolytic T-cell lines. J. Exp. Med. 149:273-278.
3. Clark, W. G., and J. S. Page. 1968. Pyrogenic responses to staphylococcal enterotoxins A and B in cats. J. Bacteriol. 96:1940-1946.
4. Corbet, J. A., R. G. Tilton, K. Chang, K. S. Hasan, Y. Ido, J. L. Wang, M. A. Sweetland, J. R. Lancaster, Jr., J. R. Williamson, and M. U. McDaniel. 1992. Aminoguanidine, a novel inhibitor of nitric oxide formation, prevent diabetic vascular dysfunction. Diabetes 41:552-556.
5. Fleischer, B., and H. Schrezenmeier. 1988. T cell stimulation by staphylococcal enterotoxins. Clonally variable response and requirement for major histocompatibility complex class II molecules on accessory or target cells. J. Exp. Med. 167:1697-1707.
6. Föstermann, U., H. H. H. W. Schmidt, J. S. Pollock, H. Sheng, J. A. Mitchell, T. D. Warner, M. Nakane, and F. Murad. 1991. Isoforms of nitric oxide synthase, characterization and purification from different cell types. Biochem. Pharmacol. 42:1849-1857.
7. Fraser, J. D. 1989. High affinity binding sites of staphylococcal enterotoxins A and B to HLA-DR. Nature 339:221-223.
8. Griffiths, M. J. D., M. Messent, R. J. MacAllister, and T. W. Evans. 1993. Aminoguanidine selectively inhibits inducible nitric oxide synthetase. Br. J. Pharmacol. 110:963-968.
9. Hodoval, L. F., E. L. Morris, G. J. Crawley, and W. R. Beisel. 1968. Pathogenesis of lethal shock after intravenous staphylococcal enterotoxin B in monkeys. Appl. Microbiol. 16:187-192.
10. Huang, W. T., M. T. Lin, and S. J. Won. 1997. Staphylococcal enterotoxin A-induced fever is associated with increased circulating levels of cytokines in rabbits. Infect. Immun. 65:2655-2662.
11. Huang, W. T., M. T. Lin, and S. J. Won. 1997. Mechanisms and sites of pyrogenic action exerted by staphylococcal enterotoxin A in rabbits. Neurosci. Lett. 236:53-56.
12. Kappler, J., B. Kotzin, L. Herron, E. W. Gelfand, R. D. Bigler, A. Boylston, S. Carrel, D. N. Posnett, Y. Choi, and P. Marrack. 1989. Vβ-specific stimulation of human T cells by staphylococcal toxins. Science 244:811-813.
13. G-methyl-L-arginine, an inhibitor of inducible nitric oxide synthase. Biochem. Biophys. Res. Commun. 172:1132-1135.
14. Kotb, M. 1995. Bacterial pyrogenic exotoxins as superantigens. Microbiol. Rev. 8:411-426.
15. Kotzin, B. L., D. Y. M. Leung, J. Kappler, and P. Marrack. 1993. Superantigens and human disease. Adv. Immunol. 54:99-146.
16. 2, thyrotropin-releasing hormone and β-endorphin. Neuropharmacology 24: 1039-1042.
17. Liu, C. T., and R. P. Sanders. 1980. Modification of lethality induced by staphylococcal enterotoxin B in dutch rabbits. Am. J. Vet. Res. 41:399-404.
18. Marcinkiewicz, J., and B. M. Chain. 1993. Differential regulation of cytokine production by nitric oxide. Immunology 80:146-159.
19. Marrack, P., and J. Kappler. 1990. The staphylococcal enterotoxins and their relatives. Science 248:705-711.
20. Moncada, S., R. M. J. Palmer, and E. A. Higgs. 1991. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol. Rev. 43:109-142.
21. Mulligan, M. S., R. M. J. Palmer, and E. A. Higgs. 1991. Tissue injury caused by deposition of immune complexes is L-arginine dependent. Proc. Natl. Acad. Sci. USA 88:638-644.
22. Nathan, C. F. 1992. Nitric oxide as a secretory product of mammalian cells. FASEB J. 6:3051-3064.
23. Normann, S. J., R. F. Jaeger, and R. T. Johnsey. 1969. Pathology of experimental enterotoxemia. The in vivo localization of staphylococcal enterotoxin B. Lab. Investig. 20:17-25.
24. Nussler, A. K., and T. R. Billiar. 1993. Inflammation, immunoregulation, and inducible nitric oxide synthase. J. Leukoc. Biol. 54:171-178.
25. Palmer, R. M. J., A. G. Ferrige, and S. Moncada. 1987. Nitric oxide release accounts for biological activity of endothelium-derived relaxing factor. Nature 327:524-526.
26. Pettit, G. W., M. R. Elwell, and P. B. Jahrling. 1977. Possible endotoxemia in rabbits after intravenous injection of Staphylococcus aureus enterotoxin B. J. Infect. Dis. 135:646-648.
27. Raddomski, M. W., R. M. J. Palmer, and S. Moncada. 1990. Glucocorticoids inhibit the expression of an inducible, but not the constitutive nitric oxide synthase in vascular endothelial cells. Proc. Natl. Acad. Sci. USA 87:10043-10049.
28. Rameshwar, P., and P. Gascon. 1992. Release of interleukin-1 and interleukin-6 from human monocytes by antithymocyte globulin: requirement for de novo synthesis. Blood 80:2531-2538.
29. Rothwell, N. J. 1991. Function and mechanisms of interleukin-1 in the brain. Trends Pharmacol. Sci. 12:430-436.
30. Spero, L., A. Johnson-Winergar, and J. J. Schmidt. 1988. Enterotoxins of staphylococci, p. 131-164. In M. C. Hardegree and A. T. Tu (ed.), Handbook of natural toxin. Marcel Dekker, Inc., New York, N.Y.
31. Sriskandan, S., J. Evans, and J. Cohen. 1996. Bacterial superantigen-induced human lymphocyte responses are nitric oxide dependent and mediated by IL-12 and IFN-γ J. Immunol. 156:2430-2435.
32. Taylor-Robinson, A. W., F. Y. Liew, A. Severn, D. Xu, S. McSorley, P. Garside, J. Padron, and R. S. Phillips. 1994. Regulation of the immune response by nitric oxide differentially produced by T-helper type 1 and T-helper type 2 cells. Eur. J. Immunol. 24:980-984.
33. Vink, A., P. G. Coulie, P. Wauters, R. P. Nordan, and J. V. Snick. 1988. B cell growth and differentiation activity of interleukin-HP1 and related murine plasmacytoma growth factor. Synergy with interleukin 1. Eur. J. Immunol. 18:607-612.