-
1
-
-
3142543752
-
Phosphorylation of αB-crystallin alters chaperone function through loss of dimeric substructure
-
Aquilina JA, Benesch JL, Ding LL, Yaron O, Horwitz J, Robinson CV. 2004. Phosphorylation of αB-crystallin alters chaperone function through loss of dimeric substructure. J Biol Chem 279: 28675-28680.
-
(2004)
J Biol Chem
, vol.279
, pp. 28675-28680
-
-
Aquilina, J.A.1
Benesch, J.L.2
Ding, L.L.3
Yaron, O.4
Horwitz, J.5
Robinson, C.V.6
-
2
-
-
0033574579
-
The small heat shock-related protein, Hsp20, is phosphorylated on serine 16 during cyclic nucleotide-dependent relaxation
-
Beall A, Bagwell D, Woodrum D, Stoming TA, Kato K, Suzuki A, Rasmussen H, Brophy CM. 1999. The small heat shock-related protein, Hsp20, is phosphorylated on serine 16 during cyclic nucleotide-dependent relaxation. J Biol Chem 274: 11344-11351.
-
(1999)
J Biol Chem
, vol.274
, pp. 11344-11351
-
-
Beall, A.1
Bagwell, D.2
Woodrum, D.3
Stoming, T.A.4
Kato, K.5
Suzuki, A.6
Rasmussen, H.7
Brophy, C.M.8
-
3
-
-
0037179756
-
Hsp27 upregulation and phosphorylation is required for injured sensory and motor neuron survival
-
Benn SC, Perrelet D, Kato AC, Scholz J, Decosterd I, Mannion RJ, Bakowska JC, Woolf CJ. 2002. Hsp27 upregulation and phosphorylation is required for injured sensory and motor neuron survival. Neuron 36: 45-56.
-
(2002)
Neuron
, vol.36
, pp. 45-56
-
-
Benn, S.C.1
Perrelet, D.2
Kato, A.C.3
Scholz, J.4
Decosterd, I.5
Mannion, R.J.6
Bakowska, J.C.7
Woolf, C.J.8
-
5
-
-
2642575701
-
Shocking degeneration
-
Benndorf R, Welsh MJ. 2004. Shocking degeneration. Nat Genet 36: 547-548.
-
(2004)
Nat Genet
, vol.36
, pp. 547-548
-
-
Benndorf, R.1
Welsh, M.J.2
-
6
-
-
0026348444
-
Hsp27 is a mediator of sustained smooth muscle contraction in response to bombesin
-
Bitar KN, Kaminski MS, Hailat N, Cease KB, Strahler JR. 1991. Hsp27 is a mediator of sustained smooth muscle contraction in response to bombesin. Biochem Biophys Res Commun 181: 1192-1200.
-
(1991)
Biochem Biophys Res Commun
, vol.181
, pp. 1192-1200
-
-
Bitar, K.N.1
Kaminski, M.S.2
Hailat, N.3
Cease, K.B.4
Strahler, J.R.5
-
7
-
-
0033972325
-
Subunit exchange of small heat shock proteins. Analysis of oligomer formation of alphaA-crystallin and Hsp27 by fluorescence resonance energy transfer and site-directed truncations
-
Bova MP, McHaourab HS, Han Y, Fung BK. 2000. Subunit exchange of small heat shock proteins. Analysis of oligomer formation of alphaA-crystallin and Hsp27 by fluorescence resonance energy transfer and site-directed truncations. J Biol Chem 275: 1035-1042.
-
(2000)
J Biol Chem
, vol.275
, pp. 1035-1042
-
-
Bova, M.P.1
McHaourab, H.S.2
Han, Y.3
Fung, B.K.4
-
8
-
-
0032586878
-
Mutation R120G in αB-crystallin, which is linked to a desmin-related myopathy, results in an irregular structure and defective chaperone-like function
-
Bova MP, Yaron O, Huang Q, Ding L, Haley DA, Stewart PL, Horwitz J. 1999. Mutation R120G in αB-crystallin, which is linked to a desmin-related myopathy, results in an irregular structure and defective chaperone-like function. Proc Natl Acad Sci U S A 96: 6137-6142.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 6137-6142
-
-
Bova, M.P.1
Yaron, O.2
Huang, Q.3
Ding, L.4
Haley, D.A.5
Stewart, P.L.6
Horwitz, J.7
-
10
-
-
21244489544
-
HspB8, a small heat shock protein mutated in human neuromuscular disorders, has in vivo chaperone activity in cultured cells
-
Carra S, Sivilotti M, Chavez Zobel AT, Lambert H, Landry J. 2005. HspB8, a small heat shock protein mutated in human neuromuscular disorders, has in vivo chaperone activity in cultured cells. Hum Mol Genet 14: 1659-1669.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 1659-1669
-
-
Carra, S.1
Sivilotti, M.2
Chavez Zobel, A.T.3
Lambert, H.4
Landry, J.5
-
11
-
-
0028984175
-
1H NMR spectroscopy reveals that mouse Hsp25 has a flexible C-terminal extension of 18 amino acids
-
Carver JA, Esposito G, Schwedersky G, Gaestel M. 1995. 1H NMR spectroscopy reveals that mouse Hsp25 has a flexible C-terminal extension of 18 amino acids. FEBS Lett 369: 305-310.
-
(1995)
FEBS Lett
, vol.369
, pp. 305-310
-
-
Carver, J.A.1
Esposito, G.2
Schwedersky, G.3
Gaestel, M.4
-
12
-
-
0038104369
-
Distinct chaperone mechanisms can delay the formation of aggresomes by the myopathy-causing R120G alphaB-crystallin mutant
-
Chavez-Zobel AT, Loranger A, Marceau N, Theriault JR, Lambert H, Landry J. 2003. Distinct chaperone mechanisms can delay the formation of aggresomes by the myopathy-causing R120G alphaB-crystallin mutant. Hum Mol Genet 12: 1609-1620.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 1609-1620
-
-
Chavez-Zobel, A.T.1
Loranger, A.2
Marceau, N.3
Theriault, J.R.4
Lambert, H.5
Landry, J.6
-
13
-
-
3242776825
-
Mammalian Hsp22 is a heat-inducible small heat-shock protein with chaperone-like activity
-
Chowdary TK, Raman B, Ramakrishna T, Rao CM. 2004. Mammalian Hsp22 is a heat-inducible small heat-shock protein with chaperone-like activity. Biochem J 381: 379-387.
-
(2004)
Biochem J
, vol.381
, pp. 379-387
-
-
Chowdary, T.K.1
Raman, B.2
Ramakrishna, T.3
Rao, C.M.4
-
15
-
-
2642563501
-
Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy
-
Evgrafov OV, Mersiyanova I, Irobi J, et al. 2004. Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. Nat Genet 36: 602-606.
-
(2004)
Nat Genet
, vol.36
, pp. 602-606
-
-
Evgrafov, O.V.1
Mersiyanova, I.2
Irobi, J.3
-
16
-
-
0037359564
-
The sperm outer dense fiber protein is the 10th member of the superfamily of mammalian small stress proteins
-
Fontaine JM, Rest JS, Welsh MJ, Benndorf R. 2003. The sperm outer dense fiber protein is the 10th member of the superfamily of mammalian small stress proteins. Cell Stress Chaperones 8: 62-69.
-
(2003)
Cell Stress Chaperones
, vol.8
, pp. 62-69
-
-
Fontaine, J.M.1
Rest, J.S.2
Welsh, M.J.3
Benndorf, R.4
-
17
-
-
26844557815
-
Interactions of HSP22 (HSPB8) with HSP20, αB-crystallin, and HSPB3
-
Fontaine JM, Sun X, Benndorf R, Welsh MJ. 2005. Interactions of HSP22 (HSPB8) with HSP20, αB-crystallin, and HSPB3. Biochem Biophys Res Commun 337: 1006-1011.
-
(2005)
Biochem Biophys Res Commun
, vol.337
, pp. 1006-1011
-
-
Fontaine, J.M.1
Sun, X.2
Benndorf, R.3
Welsh, M.J.4
-
18
-
-
0036372749
-
sHsp-phosphorylation: Enzymes, signaling pathways and functional implications
-
Gaestel M. 2002. sHsp-phosphorylation: enzymes, signaling pathways and functional implications. Prog Mol Subcell Biol 28: 151-169.
-
(2002)
Prog Mol Subcell Biol
, vol.28
, pp. 151-169
-
-
Gaestel, M.1
-
19
-
-
0033588216
-
A role for p38 (MAPK)/Hsp27 pathway in smooth muscle cell migration
-
Hedges JC, Dechert M, Yamboliev IA, Martin J, Hickey E, Weber LA, Gerthoffer WT. 1999. A role for p38 (MAPK)/Hsp27 pathway in smooth muscle cell migration. J Biol Chem 274: 24211-24219.
-
(1999)
J Biol Chem
, vol.274
, pp. 24211-24219
-
-
Hedges, J.C.1
Dechert, M.2
Yamboliev, I.A.3
Martin, J.4
Hickey, E.5
Weber, L.A.6
Gerthoffer, W.T.7
-
20
-
-
0036353398
-
MAP kinase pathways involving hsp27 regulate fibroblast-mediated wound contraction
-
Hirano S, Rees RS, Gilmont RR. 2002. MAP kinase pathways involving hsp27 regulate fibroblast-mediated wound contraction. J Surg Res 102: 77-84.
-
(2002)
J Surg Res
, vol.102
, pp. 77-84
-
-
Hirano, S.1
Rees, R.S.2
Gilmont, R.R.3
-
21
-
-
18744394644
-
p38 MAPK/Hsp25 signaling mediates cadmium-induced contraction of mesangial cells and renal glomeruli
-
Hirano S, Sun X, Deguzman CA, et al. 2005. p38 MAPK/Hsp25 signaling mediates cadmium-induced contraction of mesangial cells and renal glomeruli. Am J Physiol Renal Physiol 288: F1133-F1143.
-
(2005)
Am J Physiol Renal Physiol
, vol.288
-
-
Hirano, S.1
Sun, X.2
Deguzman, C.A.3
-
22
-
-
0026483279
-
Alpha-crystallin can function as a molecular chaperone
-
Horwitz J. 1992. Alpha-crystallin can function as a molecular chaperone. Proc Natl Acad Sci U S A 89: 10449-10453.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 10449-10453
-
-
Horwitz, J.1
-
23
-
-
2642539919
-
Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy
-
Irobi J, Impe KV, Seeman P, et al. 2004. Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy. Nat Genet 36: 597-601.
-
(2004)
Nat Genet
, vol.36
, pp. 597-601
-
-
Irobi, J.1
Impe, K.V.2
Seeman, P.3
-
24
-
-
0037358061
-
The human genome encodes 10 alpha-crystallin-related small heat shock proteins: HspB1-10
-
Kappé G, Franck E, Verschuure P, Boelens WC, Leunissen JA, de Jong WW. 2003. The human genome encodes 10 alpha-crystallin-related small heat shock proteins: HspB1-10. Cell Stress Chaperones 8: 53-61.
-
(2003)
Cell Stress Chaperones
, vol.8
, pp. 53-61
-
-
Kappé, G.1
Franck, E.2
Verschuure, P.3
Boelens, W.C.4
Leunissen, J.A.5
De Jong, W.W.6
-
25
-
-
0035072677
-
Protein kinase inhibitors can suppress stress-induced dissociation of Hsp27
-
Kato K, Ito H, Iwamoto I, Lida K, Inaguma Y. 2001. Protein kinase inhibitors can suppress stress-induced dissociation of Hsp27. Cell Stress Chaperones 6: 16-20.
-
(2001)
Cell Stress Chaperones
, vol.6
, pp. 16-20
-
-
Kato, K.1
Ito, H.2
Iwamoto, I.3
Lida, K.4
Inaguma, Y.5
-
26
-
-
0032561079
-
Phosphorylation of alphaB-crystallin in mitotic cells and identification of enzymatic activities responsible for phosphorylation
-
Kato K, Ito H, Kamei K, Inaguma Y, Iwamoto I, Saga S. 1998. Phosphorylation of alphaB-crystallin in mitotic cells and identification of enzymatic activities responsible for phosphorylation. J Biol Chem 273: 28346-28354.
-
(1998)
J Biol Chem
, vol.273
, pp. 28346-28354
-
-
Kato, K.1
Ito, H.2
Kamei, K.3
Inaguma, Y.4
Iwamoto, I.5
Saga, S.6
-
27
-
-
26944431622
-
Small heat shock protein 27 mutation in a Japanese patient with distal hereditary motor neuropathy
-
on-line publication ahead of print
-
Kijima K, Numakura C, Goto T, Takahashi T, Otagiri T, Umetsu K, Hayasaka K. 2005. Small heat shock protein 27 mutation in a Japanese patient with distal hereditary motor neuropathy. J Hum Genet (on-line publication ahead of print).
-
(2005)
J Hum Genet
-
-
Kijima, K.1
Numakura, C.2
Goto, T.3
Takahashi, T.4
Otagiri, T.5
Umetsu, K.6
Hayasaka, K.7
-
28
-
-
1342292267
-
Crystal structure of a small heat-shock protein
-
Kim KK, Kim R, Kim SH. 1998. Crystal structure of a small heat-shock protein. Nature 394: 595-599.
-
(1998)
Nature
, vol.394
, pp. 595-599
-
-
Kim, K.K.1
Kim, R.2
Kim, S.H.3
-
30
-
-
0033588379
-
Structural and functional consequences of the mutation of a conserved arginine residue in αA- and αB-crystallins
-
Kumar LV, Ramakrishna T, Rao CM. 1999. Structural and functional consequences of the mutation of a conserved arginine residue in αA- and αB-crystallins. J Biol Chem 274: 24137-24141.
-
(1999)
J Biol Chem
, vol.274
, pp. 24137-24141
-
-
Kumar, L.V.1
Ramakrishna, T.2
Rao, C.M.3
-
31
-
-
0026570931
-
Human hsp27 is phosphorylated by heat shock and mitogen-activated kinases that recognize the same amino acid motif as S6 kinase II
-
Landry J, Lambert H, Zhou M, Lavoie JN, Hickey E, Weber LA, Anderson CW. 1992. Human hsp27 is phosphorylated by heat shock and mitogen-activated kinases that recognize the same amino acid motif as S6 kinase II. J Biol Chem 267: 794-803.
-
(1992)
J Biol Chem
, vol.267
, pp. 794-803
-
-
Landry, J.1
Lambert, H.2
Zhou, M.3
Lavoie, J.N.4
Hickey, E.5
Weber, L.A.6
Anderson, C.W.7
-
32
-
-
0030826325
-
Structure-function studies on small heat shock protein oligomeric assembly and interaction with unfolded polypeptides
-
Leroux MR, Melki R, Gordon B, Batelier G, Candido EP. 1997. Structure-function studies on small heat shock protein oligomeric assembly and interaction with unfolded polypeptides. J Biol Chem 272: 24646-24656.
-
(1997)
J Biol Chem
, vol.272
, pp. 24646-24656
-
-
Leroux, M.R.1
Melki, R.2
Gordon, B.3
Batelier, G.4
Candido, E.P.5
-
33
-
-
0037422859
-
Mimicking phosphorylation of alphaB-crystallin on serine-59 is necessary and sufficient to provide maximal protection of cardiac myocytes from apoptosis
-
Morrison LE, Hoover HE, Thuerauf DJ, Glembotski CC. 2003. Mimicking phosphorylation of alphaB-crystallin on serine-59 is necessary and sufficient to provide maximal protection of cardiac myocytes from apoptosis. Circ Res 92: 203-211.
-
(2003)
Circ Res
, vol.92
, pp. 203-211
-
-
Morrison, L.E.1
Hoover, H.E.2
Thuerauf, D.J.3
Glembotski, C.C.4
-
34
-
-
0000843475
-
The cardiomyopathy and lens cataract mutation in alphaB-crystallin alters its protein structure, chaperone activity, and interaction with intermediate filaments in vitro
-
Perng MD, Muchowski PJ, van Den IJssel P, Wu GJ, Hutcheson AM, Clark JI, Quinlan RA. 1999. The cardiomyopathy and lens cataract mutation in alphaB-crystallin alters its protein structure, chaperone activity, and interaction with intermediate filaments in vitro. J Biol Chem 274: 33235-33243.
-
(1999)
J Biol Chem
, vol.274
, pp. 33235-33243
-
-
Perng, M.D.1
Muchowski, P.J.2
Van Den Ijssel, P.3
Wu, G.J.4
Hutcheson, A.M.5
Clark, J.I.6
Quinlan, R.A.7
-
35
-
-
0033516660
-
Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation
-
Rogalla T, Ehrnsperger M, Preville X, et al. 1999. Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation. J Biol Chem 274: 18947-18956.
-
(1999)
J Biol Chem
, vol.274
, pp. 18947-18956
-
-
Rogalla, T.1
Ehrnsperger, M.2
Preville, X.3
-
36
-
-
0033373475
-
HSP27 expression regulates CCK-induced changes of the actin cytoskeleton in CHO-CCK-A cells
-
Schäfer C, Clapp P, Welsh MJ, Benndorf R, Williams JA. 1999. HSP27 expression regulates CCK-induced changes of the actin cytoskeleton in CHO-CCK-A cells. Am J Physiol 277: C1032-C1043.
-
(1999)
Am J Physiol
, vol.277
-
-
Schäfer, C.1
Clapp, P.2
Welsh, M.J.3
Benndorf, R.4
Williams, J.A.5
-
37
-
-
0344664368
-
Myofibrillar myopathy caused by novel dominant negative αB-crystallin mutations
-
Selcen D, Engel AG. 2003. Myofibrillar myopathy caused by novel dominant negative αB-crystallin mutations. Ann Neurol 54: 804-810.
-
(2003)
Ann Neurol
, vol.54
, pp. 804-810
-
-
Selcen, D.1
Engel, A.G.2
-
38
-
-
0033984092
-
Muscle develops a specific form of small heat shock protein complex composed of MKBP/HSPB2 and HSPB3 during myogenic differentiation
-
Sugiyama Y, Suzuki A, Kishikawa M, et al. 2000. Muscle develops a specific form of small heat shock protein complex composed of MKBP/HSPB2 and HSPB3 during myogenic differentiation. J Biol Chem 275: 1095-1104.
-
(2000)
J Biol Chem
, vol.275
, pp. 1095-1104
-
-
Sugiyama, Y.1
Suzuki, A.2
Kishikawa, M.3
-
39
-
-
1342334759
-
Interaction of human Hsp22 (HspB8) with other small heat shock proteins
-
Sun X, Fontaine JM, Rest JS, Shelden EA, Welsh MJ, Benndorf R. 2003. Interaction of human Hsp22 (HspB8) with other small heat shock proteins. J Biol Chem 279: 2394-2402.
-
(2003)
J Biol Chem
, vol.279
, pp. 2394-2402
-
-
Sun, X.1
Fontaine, J.M.2
Rest, J.S.3
Shelden, E.A.4
Welsh, M.J.5
Benndorf, R.6
-
40
-
-
19944433659
-
Small heat-shock protein 22 mutated in autosomal dominant Charcot-Marie-Tooth disease type 2L
-
Tang BS, Zhao GH, Luo W, et al. 2005. Small heat-shock protein 22 mutated in autosomal dominant Charcot-Marie-Tooth disease type 2L. Hum Genet 116: 222-224.
-
(2005)
Hum Genet
, vol.116
, pp. 222-224
-
-
Tang, B.S.1
Zhao, G.H.2
Luo, W.3
-
41
-
-
2542451125
-
Essential role of the NH2-terminal WD/EPF motif in the phosphorylation-activated protective function of mammalian Hsp27
-
Theriault JR, Lambert H, Chavez-Zobel AT, Charest G, Lavigne P, Landry J. 2004. Essential role of the NH2-terminal WD/EPF motif in the phosphorylation-activated protective function of mammalian Hsp27. J Biol Chem 279: 23463-23471.
-
(2004)
J Biol Chem
, vol.279
, pp. 23463-23471
-
-
Theriault, J.R.1
Lambert, H.2
Chavez-Zobel, A.T.3
Charest, G.4
Lavigne, P.5
Landry, J.6
-
42
-
-
0035191639
-
Crystal structure and assembly of a eukaryotic small heat shock protein
-
van Montfort RL, Basha E, Friedrich KL, Slingsby C, Vierling E. 2001. Crystal structure and assembly of a eukaryotic small heat shock protein. Nat Struct Biol 8: 1025-1030.
-
(2001)
Nat Struct Biol
, vol.8
, pp. 1025-1030
-
-
Van Montfort, R.L.1
Basha, E.2
Friedrich, K.L.3
Slingsby, C.4
Vierling, E.5
-
43
-
-
0242407366
-
Expression of small heat shock proteins HspB2, HspB8, Hsp20 and cvHsp in different tissues of the perinatal developing pig
-
Verschuure P, Tatard C, Boelens WC, Grongnet JF, David JC. 2003. Expression of small heat shock proteins HspB2, HspB8, Hsp20 and cvHsp in different tissues of the perinatal developing pig. Eur J Cell Biol 82: 523-530.
-
(2003)
Eur J Cell Biol
, vol.82
, pp. 523-530
-
-
Verschuure, P.1
Tatard, C.2
Boelens, W.C.3
Grongnet, J.F.4
David, J.C.5
-
44
-
-
17344361902
-
A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy
-
Vicart P, Caron A, Guicheney P, et al. 1998. A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy. Nat Genet 20: 92-95.
-
(1998)
Nat Genet
, vol.20
, pp. 92-95
-
-
Vicart, P.1
Caron, A.2
Guicheney, P.3
-
45
-
-
0033949329
-
Evidence for modulation of smooth muscle force by the p38 MAP kinase/Hsp27 pathway
-
Yamboliev IA, Hedges JC, Mutnick JL-M, Adam LP, Gerthoffer WT. 2000. Evidence for modulation of smooth muscle force by the p38 MAP kinase/Hsp27 pathway. Am J Physiol Heart Circ Physiol 278: H1899-H1907.
-
(2000)
Am J Physiol Heart Circ Physiol
, vol.278
-
-
Yamboliev, I.A.1
Hedges, J.C.2
Mutnick, J.L.-M.3
Adam, L.P.4
Gerthoffer, W.T.5
|