Inhibitors of alternative pathways of arachidonate metabolism differentially affect fever in mice

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 275, Issue 4 44-4, 1998, Pages

  Kozak, Wieslaw ^a   Archuleta, Inez ^a   Mayfield, Kimberly P ^a   Kozak, Anna ^a   Rudolph, Karin ^a   Kluger, Matthew J ^a  

^a LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

Author keywords

Clotrimazole; Cyclooxygenases; Cytochrome P 450; Cytokines; Endotoxin; Esculetin; Indomethacin; Lipoxygenases; Nordihydroguaiaretic acid; Phenidone; SKF 525A; Temperature regulation

Indexed keywords

ARACHIDONIC ACID; CYTOCHROME P450; ENDOTOXIN; LIPOXYGENASE; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR;

ANIMAL EXPERIMENT; ARACHIDONIC ACID METABOLISM; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEVER; INFLAMMATION; INJURY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; THERMOREGULATION;

EID: 0031793054     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1998.275.4.r1031     Document Type: Article

References (44)

1. Agarwal, R., Z. Y. Wang, D. P. Bik, and H. Mukhtar. Nordihydroguaiaretic acid, an inhibitor of lipoxygenase, also inhibits cytochrome P-450-mediated monooxygenase activity in rat epidermal and hepatic microsomes. Drug Metab. Dispos. 19: 620-624, 1991.
2. Baumann, J., F. Von Bruchhausen, and G. Wurm. Flavonoids and related compounds as inhibitors of arachidonic acid peroxidation. Prostaglandins 20: 627-629, 1980.
3. Bhattacherjee, P., N. K. Boughton-Smith, R. L. Follenfant, L. G. Garland, G. A. Higgs, H. F. Hodson, P. J. Islip, W. P. Jackson, S. Moncada, A. N. Payne, R. W. Randall, C. H. Reynolds, J. A. Salmon, J. E. Tateson, and B. J. R. Whittle. The effects of a novel series of selective inhibitors of arachidonate 5-lipoxygenase on anaphylactic and inflammatory responses. Ann. NY Acad. Sci. 542: 307-320, 1988.
4. 2: a putative fever mediator. In: Fever: Basic Mechanisms and Management, edited by P.A. Mackowiak. New York: Lippincott-Raven, 1997, p. 117-145.
5. Boeynaems, J. M., D. Demolle, and A. Van Coevorden. Prostacyclin-stimulating drugs: new perspectives. Prostaglandins 32: 145-149, 1986.
6. Boulant, J. A. Thermoregulation. In: Fever: Basic Mechanisms and Management, edited by P. A. Mackowiak. New York: Lippincott-Raven, 1997, p. 35-58.
7. Breder, C. D., and C. B. Saper. Expression of inducible cyclooxygenase mRNA in the mouse brain after systemic administration of bacterial lipopolysaccharide. Brain Res. 713: 64-69, 1996.
8. Cai, Y., A.-K. Sohlenius, K. Andersson, C. Sundberg, and J. W. Depierre. Effect of acetylsalicylic acid on parameters related to peroxisome proliferation in mouse liver. Biochem. Pharmacol. 47: 2213-2219, 1994.
9. Capdevila, J. H., and J. R. Falck. Cytochrome P-450 and the bioactivation of arachidonic acid. Blood Vessels 26: 54-57, 1989.
10. Capdevila, J. H., L. Gil, M. Orellana, L. J. Marnett, J. I. Mason, P. Yadagiri, and J. R. Falck. Inhibitors of cytochrome P-450-dependent arachidonic acid metabolism. Arch. Biochem. Biophys. 261: 257-263, 1988.
11. Clausen, T., C. Van Hardevald, and M. E. Everts. Significance of cation transport in control of energy metabolism and thermogenesis. Physiol. Rev. 71: 733-774, 1991.
12. Cornell, R. P. Central interleukin-1-elicited hyprinsulinemia is mediated by prostaglandins but not autonomics. Am. J. Physiol. 257 (Regulatory Integrative Comp. Physiol. 26): R839-R846, 1989.
13. 1. J. Physiol. (Lond.) 217: 547-556, 1971.
14. Fitzpatrick, F. A., M. D. Ennis, M. E. Baze, M. A. Wynalda, J. E. Mcgee, and W. F. Liggett. Inhibition of cyclooxygenase activity and platelet eggregation by epoxyeicosatrienoic acids. J. Biol. Chem. 261: 15334-15338, 1986.
15. Flynn, D. L., M. F. Rafferty, and A. M. Boctor. Inhibiton of 5-hydroxyeicosatetraenoic acid (5-HETE) formation in intact human neutrophils by naturally-occuring diarylheptanoids: inhibitory activities of curcuminoids and yakuchinones. Prostaglandins Leukot. Med. 22: 357-360, 1986.
16. Ghezzi, P., B. Saccardo, P. Villa, V. Rossi, M. Bianchi, and C. A. Dinarello. Role of interleukin-1 in the depression of liver drug metabolism by endotoxin. Infect. Immun. 54: 837-840, 1986.
17. Ghosh, J., and C. E. Myers. Arachidonic acid stimulates prostate cancer cell growth: critical role of 5-lipoxygenase. Biochem. Biophys. Res. Commun. 235: 418-423, 1997.
18. Hagihara, K., S. Shisaka, Y. Lee, J. Kato, O. Hatano, A. Takakusu, Y. Emi, T. Omura, and M. Tohyama. Presence of sex difference of cytochrome P-450 in the rat preoptic area and hypothalamus with reference to coexistence with oxytocin. Brain Res. 515: 69-78, 1990.
19. 2 in a murine model of inflammation: possible role of cyclooxygenase-2. Proc. Natl. Acad. Sci. USA 93: 4885-4890, 1996.
20. Hynes, N., I. Bishai, J. Lees, and F. Coceani. Leukotrienes in brain: natural occurrence and induced changes. Brain Res. 553: 4-13, 1991.
21. Karara, A., E. Dishman, I. Blair, J. R. Falck, and J. H. Capdevila. Endogenous epoxyeicosatrienoic acids. J. Biol. Chem. 264: 19822-19827, 1989.
22. Kluger, M. J., W. Kozak, L. R. Leon, D. Soszynski, and C. A. Conn. Cytokines and fever. Neuroimmunomodulation 2: 216-223, 1995.
23. Koj, A. Initiation of acute phase response and synthesis of cytokines. Biochim. Biophys. Acta 1317: 84-94, 1996.
24. Kozak, W., C. A. Conn, and M. J. Kluger. Lipopolysaccharide induces fever and depresses locomotor activity in unrestrained mice. Am. J. Physiol. 266 (Regulatory Integrative Comp. Physiol. 35): R125-R135, 1994.
25. Kozak, W., D. Soszynski, K. Rudolph, L. R. Leon, C. A. Conn, and M. J. Kluger. Soluble tumor necrosis factor-α receptor prevents decrease of body temperature in mice treated with indomethacin and lipopolysaccharide. Ann. NY Acad. Sci. 813: 264-271, 1997.
26. Kundu, R. K., J. H. Tonsgard, and G. S. Getz. Induction of omega-oxidation of monocarboxylic acids. J. Clin. Invest. 88: 1865-1872, 1991.
27. Lemay, L. G., A. Vander, and M. J. Kluger. Role of interleukin-6 in fever in the rat. Am. J. Physiol. 259 (Regulatory Integrative Comp. Physiol. 28): R126-R132, 1990.
28. Mashburn, T. A., Jr., J. Llanos, R. A. Ahokas, and C. M. Blatteis. Thermal and acute-phase protein responses of guinea pigs to intrapreoptic injections of leukotrienes. Brain Res. 376: 285-291, 1986.
29. McGiff, J. C. Cytochrome P-450 metabolism of arachidonic acid. Annu. Rev. Pharmacol. Toxicol. 31: 339-369, 1991.
30. 1 as a modulator for temperature regulation in the central nervous system of the cat. J. Physiol. (Lond.) 207: 76-77, 1970.
31. Morgan, E. T. Suppression of constitutive cytochrome P-450 gene expression in livers of rats undergoing an acute phase response to endotoxin. Mol. Pharmacol. 36: 699-707, 1989.
32. Muller-Peddinghaus, R. C. Kohlsdorfer, P. Theisen-Popp, R. Fruchtmann, E. Perzborn, B. Beckermann, K. Buhner, H. J. Ahr, and K. H. Mohrs. BAY X1005, a new inhibitor of leukotriene synthesis: in vivo inflammation pharmacology and pharmacokinetics. J. Pharmacol Exp. Ther. 267: 51-57, 1993.
33. Murray, M., and G. F. Reidy. Selectivity in the inhibition of mammalian cytochromes P-450 by chemical agents. Pharmacol. Rev. 42: 85-101, 1990.
34. Nakashima, T., Y. Harada, S. Miyata, and T. Kiyohara. Inhibitors of cytochrome P-450 augment fever induced by interleukin-1. Am. J. Physiol. 271 (Regulatory Integrative Comp. Physiol. 40): R1274-R1279, 1996.
35. Negro-Vilar, A., G. Snyder, J. Falck, N. Chacos, and J. H. Capdevila. Involvement of eicosanoids in release of oxytocin and vasopressin from the neural lobe of the rat pituitary. Endocrinology 116: 2663-2668, 1985.
36. Neichi, T., Y. Koshihara, and S. Murata. Inhibitory effect of esculetin on 5-lipoxygenase and leukotriene biosynthesis. Biochim. Biophys. Acta 753: 130-132, 1983.
37. Ohishi, S., I. Utsunomija, T. Yamamoto, Y. Komuro, and Y. Hara. Effects of prostaglandins and cyclic AMP on cytokine production in rat leukocytes. Eur. J. Pharmacol. 300: 255-259, 1996.
38. 4 in the rat: lack of febrile effect. Brain Res. 295: 283-288, 1984.
39. Pankow, D., B. Damme, and K. Schror. Acetylsalicylic acid inducer of cytochrome P-450. Arch. Toxicol. 68: 261-265, 1994.
40. Pittman, Q. J., and M. F. Wilkinson. Central arginine vasopressin and endogenous antipyresis. Can. J. Physiol. Pharmacol. 70: 786-790, 1992.
41. Shedlofsky, S. I., B. C. Israel, C. J. Mcclain, D. B. Hill, and R. A. Blouin. Endotoxin administration to humans inhibits hepatic cytochrome P-450-mediated drug metabolism. J. Clin. Invest. 94: 2209-2214, 1994.
42. Vane, J. R. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nature 231: 272-273, 1971.
43. Vazquez, B., A. Rios, and B. Escalante. Arachidonic acid metabolism modulates vasopressin-induced renal vasoconstriction. Life Sci. 56: 1455-1466, 1995.
44. Warner, M., M. Stromstedt, A. Wyss, and J. A. Gustafsson. Regulation of cytochrome P-450 in the central nervous system. J. Steroid Biochem. Mol. Biol. 47: 191-194, 1993.