Modulation of allergic responses in mice by using biodegradable poly(lactide-co-glycolide) microspheres

Journal of Allergy and Clinical Immunology

Volumn 114, Issue 4, 2004, Pages 943-950

  Jilek, Samantha ^a   Walter, Elke ^a   Merkle, Hans P ^a   Corthésy, Blaise ^b  

^a ETH ZURICH   (Switzerland)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

Allergy; immunomodulation; microspheres; T H1 T H2 responses

Indexed keywords

ALLERGEN; ANION; BEE VENOM; CATION; DNA VACCINE; GAMMA INTERFERON; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; INTERLEUKIN 10; INTERLEUKIN 4; MICROSPHERE; PHOSPHOLIPASE A2; PLASMID DNA; POLYGLACTIN;

ALLERGIC REACTION; ALLERGY; ANAPHYLAXIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIODEGRADATION; CELL PROLIFERATION; CELLULAR IMMUNITY; CONTROLLED STUDY; DRUG FORMULATION; DRUG POTENTIATION; DRUG TOLERANCE; EVALUATION; FEMALE; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOMODULATION; IMMUNOSUPPRESSIVE TREATMENT; LETHAL DOSE; MOUSE; NONHUMAN; OBSERVATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSITIZATION; SPLEEN CELL; T LYMPHOCYTE; TH1 CELL; TH2 CELL; VACCINATION;

ABSORBABLE IMPLANTS; ANIMALS; BEE VENOMS; BIOCOMPATIBLE MATERIALS; DRUG CARRIERS; HYPERSENSITIVITY; INJECTIONS, SUBCUTANEOUS; INTERLEUKIN-10; MICE; MICROSPHERES; MODELS, ANIMAL; PHOSPHOLIPASES A; POLYGLACTIN 910; T-LYMPHOCYTES; VACCINATION; VACCINES, DNA;

EID: 4944260149     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2004.05.065     Document Type: Article

References (45)

1. J. Ring, B. Eberlein-Koenig, and H. Behrendt Environmental pollution and allergy Ann Allergy Asthma Immunol 87 2001 2 6
2. M. Jutel, W.J. Pichler, D. Skrbic, A. Urwyler, C. Dahinden, and U.R. Muller Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFN-gamma secretion in specific allergen-stimulated T cell cultures J Immunol 154 1995 4187 4194
3. M. Astori, C. von Garnier, A. Kettner, N. Dufour, G. Corradin, and F. Spertini Inducing tolerance by intranasal administration of long peptides in naive and primed CBA/J mice J Immunol 165 2000 3497 3505
4. C. von Garnier, M. Astori, A. Kettner, N. Dufour, C. Heusser, and G. Corradin Allergen-derived long peptide immunotherapy down-regulates specific IgE response and protects from anaphylaxis Eur J Immunol 30 2000 1638 1645
5. R. Kammerer, Y. Chvatchko, A. Kettner, N. Dufour, G. Corradin, and F. Spertini Modulation of T-cell response to phospholipase A2 and phospholipase A2-derived peptides by conventional bee venom immunotherapy J Allergy Clin Immunol 100 1997 96 103
6. R.E. Reisman Venom hypersensitivity J Allergy Clin Immunol 94 1994 651 658
7. E. Raz, H. Tighe, Y. Sato, M. Corr, J.A. Dudler, and M. Roman Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization Proc Natl Acad Sci U S A 93 1996 5141 5145
8. S. Jilek, C. Barbey, F. Spertini, and B. Corthésy Antigen-independent suppression of the allergic immune response to bee venom phospholipase A(2) by DNA vaccination in CBA/J mice J Immunol 166 2001 3612 3621
9. P. Johansen, Y. Men, H.P. Merkle, and B. Gander Revisiting PLA/PLGA microspheres: an analysis of their potential in parenteral vaccination Eur J Pharm Biopharm 50 2000 129 146
10. C. Berkland, M. King, A. Cox, K. Kim, and D.W. Pack Precise control of PLG microsphere size provides enhanced control of drug release rate J Control Release 82 2002 137 147
11. C. Berkland, K. Kim, and D.W. Pack PLG microsphere size control drug release rate through several competing factors Pharm Res 20 2003 1055 1062
12. E. Walter, D. Dreher, M. Kok, L. Thiele, S.G. Kiama, and P. Gehr Hydrophilic poly(DL-lactide-co-gylcolide) microspheres for the delivery of DNA to human-derived macrophages and dendritic cells J Control Release 76 2001 149 168
13. L. Lunsford, U. McKeever, V. Eckstein, and M.L. Hedley Tissue distribution and persistence in mice of plasmid DNA encapsulated in PLGA-based microsphere delivery vehicle J Drug Target 8 2000 39 50
14. K.D. Newman, P. Elamanchili, G.S. Kwon, and J. Samuel Uptake of poly(D, L-lactic-co-glycolic acid) microspheres by antigen-presenting cells in vivo J Biomed Mater Res 60 2002 480 486
15. M. Kempf, B. Mandal, S. Jilek, L. Thiele, J. Vörös, and M. Textor Improved stimulation of human dendritic cells by receptor engagement with surface-modified microparticles J Drug Target 11 2003 11 18
16. S. Jilek, M. Ulrich, H.P. Merkle, and E. Walter Composition and surface charge of DNA-loaded microparticles determine maturation and cytokine secretion in human dendritic cells Pharm Res 21 2004 1240 1247
17. Y. Men, R. Audran, C. Thomasin, G. Eberl, S. Demotz, and H.P. Merkle MHC class I- and class II-restricted processing and presentation of microencapsulated antigens Vaccine 17 1999 1047 1056
18. R. Audran, K. Peter, J. Dannull, Y. Men, E. Scandella, and M. Groettrup Encapsulation of peptides in biodegradable microspheres prolongs their MHC class-I presentation by dendritic cells and macrophages in vitro Vaccine 21 2003 1250 1255
19. J. Banchereau, F. Brière, C. Caux, J. Davoust, S. Lebecque, and Y.-J. Liu Immunobiology of dendritic cells Annu Rev Immunol 18 2000 767 811
20. E. Walter, K. Moelling, J. Pavlovic, and H.P. Merkle Microencapsulation of DNA using poly(DL-lactide-co-glycolide): stability issues and release characteristics J Control Release 61 1999 361 374
21. A.M. Tinsley-Bown, R. Fretwell, A.B. Dowsett, S.L. Davis, and G.H. Farrar Formulation of poly(D, L-lactic-co-glycolic acid) microparticles for rapid plasmid DNA delivery J Control Release 66 2000 229 241
22. E. Walter, and H.P. Merkle Microparticle-mediated transfection of non-phagocytic cells in vitro J Drug Target 10 2002 11 21
23. M.L. Hedley, J. Curley, and R. Urban Microspheres containing plasmid-encoded antigens elicit cytotoxic T-cell responses Nat Med 4 1998 365 368
24. D. O'Hagan, M. Singh, M. Ugozzoli, C. Wild, S. Barnett, and M. Chen Induction of potent immune responses by cationic microparticles with adsorbed immunodeficiency virus DNA vaccines J Virol 75 2001 9037 9043
25. K.S. Denis-Mize, M. Dupuis, M.L. MacKichan, M. Singh, B. Doe, and D. O'Hagan Plasmid DNA adsorbed onto cationic microparticles mediates target gene expression and antigen presentation by dendritic cells Gene Ther 7 2000 2105 2112
26. M. Manthorpe, F. Conrefert-Jensen, J. Hartikka, J. Felgner, A. Rundell, and M. Margalith Gene therapy by intramuscular injection of plasmid DNA: studies on firefly luciferase gene expression in mice Human Gene Ther 4 1993 419 431
27. C. Thomasin, G. Corradin, Y. Men, H.P. Merkle, and B. Gander Tetanus toxoid and synthetic malaria antigen containing poly(lactide)/poly(lactide-co- glycolide) microspheres: importance of polymer degradation and antigen release for immune response J Control Release 41 1996 131 145
28. P. Chomczynski, and N. Sacchi Singel-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction Anal Biochem 162 1987 156 159
29. S. Romagnani The Th1/Th2 paradigm and allergic disorders Allergy 53 1998 12 15
30. K.W. Moore, R. de Waal Malefyt, R.L. Coffman, and A. O'Garra Interleukin-10 and the interleukin-10 receptor Annu Rev Immunol 19 2001 683 765
31. K. Asadullah, W. Sterry, and H.D. Volk Interleukin-10 therapy-review of a new approach Pharmacol Rev 55 2003 241 269
32. B. Klencke, M. Matijevic, R.G. Urban, J.L. Lathey, M.L. Hedley, and M. Berry Enscapsulated plasmid DNA treatment for human papillomavirus 16-associated anal dysplasia: a phase I study of ZYC101 Clin Cancer Res 8 2002 1028 1037
33. E.E. Sheets, R.G. Urban, C.P. Crum, M.L. Hedley, J.A. Politch, and M.A. Gold Immunotherapy of human cervical high-grade cervical intraepithelial neoplasia with microparticle-delivered human papillomavirus 16 E7 plasmid DNA Am J Obstet Gynecol 188 2003 916 926
34. E. Fattal, S. Pecquet, P. Couvreur, and A. Andremont Biodegradable microparticles for the mucosal delivery of antibacterial and dietary antigens Int J Pharm 242 2002 15 24
35. P. Strong, H. Clark, and K. Reid Intranasal application of chitin microparticles down-regulates symptoms of allergic hypersensitivity to Dermatophagoides pteronyssinus and Aspergillus fumigatus in murine models of allergy Clin Exp Allergy 32 2002 1794 1800
36. Y. Shibata, L.A. Foster, J.F. Bradfield, and Q.N. Myrvik Oral administration of chitin down-regulates serum IgE levels and lung eosinophilia in the allergic mouse J Immunol 164 2000 1314 1321
37. L. Thiele, H.P. Merkle, and E. Walter Phagocytosis and phagosomal fate of surface-modified microparticles in dendritic cells and macrophages Pharm Res 20 2003 221 228
38. S. Kubo, T. Nakayama, K. Matsuoka, H. Yonekawa, and H. Karasuyama Long term maintenance of IgE-mediated memory in mast cells in the absence of detectable serum IgE J Immunol 170 2003 775 780
39. I. Bellinghausen, J. Knop, and J. Saloga Role of interleukin 10-producing T cells in specific (allergen) immunotherapy Allergy Clin Immunol Int 12 2000 20 25
40. C.A. Akdis, T. Blesken, M. Akdis, B. Wuthrich, and K. Blaser Role of interleukin 10 in specific immunotherapy J Clin Invest 102 1998 98 106
41. F. Willems, A. Marchant, J.P. Delville, C. Gerard, A. Delvaux, and T. Velu Interleukin-10 inhibits B7 and intercellular adhesion molecule-1 expression on human monocytes Eur J Immunol 24 1994 1007 1009
42. M. Pierkes, I. Bellinghausen, T. Hultsch, G. Metz, J. Knop, and J. Saloga Decreased release of histamine and sulfidoleukotrienes by human peripheral blood leukocytes after wasp venom immunotherapy is partially due to induction of IL-10 and IFN-gamma production of T cells J Allergy Clin Immunol 103 1999 326 332
43. O. Akbari, R.H. DeKruyff, and D.T. Umetsu Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen Nat Immunol 2 2001 725 731
44. V. Julia, M. Rassoulzadegan, and N. Glaichenhaus Resistance to Leishmania major induced by tolerance to a single antigen Science 274 1996 421 423
45. S. Romagnani Atopic allergy and other hypersensitivities Curr Opin Immunol 7 1995 745 750