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Volumn 19, Issue 1, 2000, Pages 21-34

Dacarbazine-based chemotherapy for metastatic melanoma: Thirty-year experience overview

Author keywords

DTIC based chemotherapy; Metastatic melanoma; Systemic chemotherapy

Indexed keywords

BLEOMYCIN; CARMUSTINE; CISPLATIN; DACARBAZINE; LOMUSTINE; NITROSOUREA DERIVATIVE; TAMOXIFEN; VINBLASTINE; VINCRISTINE;

EID: 0034124656     PISSN: 03929078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (334)

References (105)
  • 1
    • 0014762189 scopus 로고
    • Clinical trials with the antitumor agent 5-(3,3-dimethyl-1-triazeno) imidazole-4-carboxamide (NSC 45388)
    • Luce J.K., Thurman W.G., Isaacs B.L., Talley R.W.: Clinical trials with the antitumor agent 5-(3,3-dimethyl-1-triazeno) imidazole-4-carboxamide (NSC 45388). Cancer Chemother. Rep. 54: 119-124, 1970.
    • (1970) Cancer Chemother. Rep. , vol.54 , pp. 119-124
    • Luce, J.K.1    Thurman, W.G.2    Isaacs, B.L.3    Talley, R.W.4
  • 2
    • 0015269578 scopus 로고
    • Combination phase I-II study of imidazole carboxamide (NSC 45388)
    • Wagner D.E., Ramirez G., Weiss A.J. and Hill G. jr.: Combination phase I-II study of imidazole carboxamide (NSC 45388) Oncology 26:310-316, 1971.
    • (1971) Oncology , vol.26 , pp. 310-316
    • Wagner, D.E.1    Ramirez, G.2    Weiss, A.J.3    Hill Jr., G.4
  • 3
    • 0015197656 scopus 로고
    • Clinical evaluation of 5-(3,3-dimethyl-1-triazeno) imidazole-4-carboxamide in malignant melanoma and other neoplasms: Comparison of twice-weekly and daily administration schedules
    • Gottlieb J.A. and Serpick A.A.: Clinical evaluation of 5-(3,3-dimethyl-1-triazeno) imidazole-4-carboxamide in malignant melanoma and other neoplasms: comparison of twice-weekly and daily administration schedules. Oncology 25: 225-233, 1971.
    • (1971) Oncology , vol.25 , pp. 225-233
    • Gottlieb, J.A.1    Serpick, A.A.2
  • 4
    • 0015038553 scopus 로고
    • Intermittent treatment of metastatic malignant melanoma with high-dose 5-(3,3-dimethyl-1-triazeno) imidazole-4-carboxamide (NSC 45388)
    • Cowan D.H. and Bergsagel D.E.: Intermittent treatment of metastatic malignant melanoma with high-dose 5-(3,3-dimethyl-1-triazeno) imidazole-4-carboxamide (NSC 45388). Cancer Chemother. Rep. 55: 175-181, 1971.
    • (1971) Cancer Chemother. Rep. , vol.55 , pp. 175-181
    • Cowan, D.H.1    Bergsagel, D.E.2
  • 6
    • 0017135828 scopus 로고
    • Experimental studies at Southern Research Institutes with DTIC (NSC 45388)
    • Montgomery J.A.: Experimental studies at Southern Research Institutes with DTIC (NSC 45388). Cancer Treat. Rep. 60: 125-134, 1976.
    • (1976) Cancer Treat. Rep. , vol.60 , pp. 125-134
    • Montgomery, J.A.1
  • 9
    • 0024673467 scopus 로고
    • Hepatic vascular toxicity of dacarbazine (DTIC): Not a rare complication
    • Marsh J.C.: Hepatic vascular toxicity of dacarbazine (DTIC): not a rare complication. Hepatol. 9: 790, 1989.
    • (1989) Hepatol. , vol.9 , pp. 790
    • Marsh, J.C.1
  • 10
    • 0017072029 scopus 로고
    • Randomized prospective trial of DTIC (NSC-45388) alone versus BCNU (NSC-409962) plus vincristine (NSC-67574) in the treatment of metastatic malignant melanoma
    • Bellet R.E., Mastrangelo M.J., Laucius J.F., Bodurtha A.J.: Randomized prospective trial of DTIC (NSC-45388) alone versus BCNU (NSC-409962) plus vincristine (NSC-67574) in the treatment of metastatic malignant melanoma. Cancer Treat. Rep. 60: 595-600, 1976.
    • (1976) Cancer Treat. Rep. , vol.60 , pp. 595-600
    • Bellet, R.E.1    Mastrangelo, M.J.2    Laucius, J.F.3    Bodurtha, A.J.4
  • 11
    • 0015026753 scopus 로고
    • Imidazole carboxamide therapy in advanced malignant melanoma
    • Burke P.J., McCarthy W.H., Milton G.W.: Imidazole carboxamide therapy in advanced malignant melanoma. Cancer 27: 744-750, 1971.
    • (1971) Cancer , vol.27 , pp. 744-750
    • Burke, P.J.1    McCarthy, W.H.2    Milton, G.W.3
  • 12
    • 0025837770 scopus 로고
    • Improved results with the addition of interferon alfa-2b to dacarbazine in the treatment of patients with metastatic malignant melanoma
    • Falkson C.I., Falkson G., Falkson H.C.: Improved results with the addition of interferon alfa-2b to dacarbazine in the treatment of patients with metastatic malignant melanoma. J. Clin. Oncol. 9: 1403-1408, 1991.
    • (1991) J. Clin. Oncol. , vol.9 , pp. 1403-1408
    • Falkson, C.I.1    Falkson, G.2    Falkson, H.C.3
  • 13
    • 0028218050 scopus 로고
    • Multicentre randomized trial of dacarbazinc alone or in combination with two different doses and schedules of interferon alfa-2a in the treatment of advanced melanoma
    • Bajetta E., Di Leo A., Zampino M.G. et al.: Multicentre randomized trial of dacarbazinc alone or in combination with two different doses and schedules of interferon alfa-2a in the treatment of advanced melanoma. J. Clin. Oncol. 12: 806-811, 1994.
    • (1994) J. Clin. Oncol. , vol.12 , pp. 806-811
    • Bajetta, E.1    Di Leo, A.2    Zampino, M.G.3
  • 15
    • 0018192522 scopus 로고
    • Phase II study of ICRF-159 versus combination cis-dichlorodiammineplatinum (II) and DTIC in patients with disseminated malienant melanoma
    • Ahmann D.L, Edmonson J.H., Frytak S., Kvols L.K., Bisel H.F., Rubin J.: Phase II study of ICRF-159 versus combination cis-dichlorodiammineplatinum (II) and DTIC in patients with disseminated malienant melanoma. Cancer Treat. Rep. 62 (1): 151-153, 1978.
    • (1978) Cancer Treat. Rep. , vol.62 , Issue.1 , pp. 151-153
    • Ahmann, D.L.1    Edmonson, J.H.2    Frytak, S.3    Kvols, L.K.4    Bisel, H.F.5    Rubin, J.6
  • 16
    • 0018578515 scopus 로고
    • cis-Dichlorodiammineplatinum (II) alone and combined with DTIC for treatment of disseminated malignant melanoma
    • Goodnight J.E. Jr, Mosely H.S., Eilber F.R., Sarna G., Morton D.L.: cis-Dichlorodiammineplatinum (II) alone and combined with DTIC for treatment of disseminated malignant melanoma. Cancer. Treat. Rep. 63: 2005-2007, 1979.
    • (1979) Cancer. Treat. Rep. , vol.63 , pp. 2005-2007
    • Goodnight Jr., J.E.1    Mosely, H.S.2    Eilber, F.R.3    Sarna, G.4    Morton, D.L.5
  • 17
  • 19
    • 0023258489 scopus 로고
    • WR-2721 and high-dose cisplatin: An active combination in the treatment of metastatic melanoma
    • Glover D., Glick J.H., Weiler C., Fox K., Guerry D.: WR-2721 and high-dose cisplatin: an active combination in the treatment of metastatic melanoma. J. Clin. Oncol. 5 (4): 574-578, 1987.
    • (1987) J. Clin. Oncol. , vol.5 , Issue.4 , pp. 574-578
    • Glover, D.1    Glick, J.H.2    Weiler, C.3    Fox, K.4    Guerry, D.5
  • 20
    • 0025753102 scopus 로고
    • High-dose cisplatin plus dacarbazine in the treatment of metastatic melanoma
    • Murren J.R., De Rosa W, Durivage H.J., Davis C., Makuch R., Portlock C.S.: High-dose cisplatin plus dacarbazine in the treatment of metastatic melanoma. Cancer 67: 1514-1517, 1991.
    • (1991) Cancer , vol.67 , pp. 1514-1517
    • Murren, J.R.1    De Rosa, W.2    Durivage, H.J.3    Davis, C.4    Makuch, R.5    Portlock, C.S.6
  • 21
    • 0026000818 scopus 로고
    • A phase II trial of high-dose cisplatin and dacarbazine. Lack of efficacy of high-dose, cisplatin-based therapy for metastatic melanoma
    • Steffens T.A., Bajorin D.F., Chapman P.B. et al.: A phase II trial of high-dose cisplatin and dacarbazine. Lack of efficacy of high-dose, cisplatin-based therapy for metastatic melanoma. Cancer 68: 1230-1237, 1991.
    • (1991) Cancer , vol.68 , pp. 1230-1237
    • Steffens, T.A.1    Bajorin, D.F.2    Chapman, P.B.3
  • 22
    • 0025697168 scopus 로고
    • High-dose cisplatin and dacarbazine in the treatment of metastatic melanoma
    • Luger S.M., Kirkwood J.M., Ernstoff M.S., Vlock D.R.: High-dose cisplatin and dacarbazine in the treatment of metastatic melanoma. J. Natl. Cancer Inst. 82: 1934-1937, 1990.
    • (1990) J. Natl. Cancer Inst. , vol.82 , pp. 1934-1937
    • Luger, S.M.1    Kirkwood, J.M.2    Ernstoff, M.S.3    Vlock, D.R.4
  • 23
    • 0030925810 scopus 로고    scopus 로고
    • The treatment of metastatic melanoma with chemotherapy and biologies
    • Atkins M.B.: The treatment of metastatic melanoma with chemotherapy and biologies. Curr. Opin. Oncol. 9: 205-213, 1997.
    • (1997) Curr. Opin. Oncol. , vol.9 , pp. 205-213
    • Atkins, M.B.1
  • 24
    • 0015442058 scopus 로고
    • Therapy of malignant melanoma with an imidazole carboxamide and bischloroethyl nitrosourea
    • Costanza M.E., Nathanson L., Lenhard R. et al.: Therapy of malignant melanoma with an imidazole carboxamide and bischloroethyl nitrosourea. Cancer 30: 1457-1461, 1972.
    • (1972) Cancer , vol.30 , pp. 1457-1461
    • Costanza, M.E.1    Nathanson, L.2    Lenhard, R.3
  • 25
    • 0017754120 scopus 로고
    • Results with methyl-CCNU and DTIC in metastatic melanoma
    • Costanza M.E., Nathanson L., Schoenfeld D. et al.: Results with methyl-CCNU and DTIC in metastatic melanoma. Cancer 40: 1010-1015, 1977.
    • (1977) Cancer , vol.40 , pp. 1010-1015
    • Costanza, M.E.1    Nathanson, L.2    Schoenfeld, D.3
  • 26
    • 1642592949 scopus 로고
    • Fotemustine: A new nitrosourea drug in the treatment of melanoma
    • Schallreuter K.V., Wood J.M.: Fotemustine: a new nitrosourea drug in the treatment of melanoma. J. Cancer Res. Clin. Oncol. 116: 423, 1990.
    • (1990) J. Cancer Res. Clin. Oncol. , vol.116 , pp. 423
    • Schallreuter, K.V.1    Wood, J.M.2
  • 27
    • 0023744039 scopus 로고
    • Interim report of phase II study of new nitrosourea S10036 in disseminated malignant melanoma
    • Khayat D., Bizzari J.P., Frenay M. et al.: Interim report of phase II study of new nitrosourea S10036 in disseminated malignant melanoma. J. Natl. Cancer Inst. 80: 1407-1408, 1988.
    • (1988) J. Natl. Cancer Inst. , vol.80 , pp. 1407-1408
    • Khayat, D.1    Bizzari, J.P.2    Frenay, M.3
  • 28
    • 0025109821 scopus 로고
    • Final report of phase II study of the nitrosourea fotemustine (S 10036) in 153 patients with disseminated malignant melanoma including patients with cerebral metastases
    • Jacquillat C., Khayat D., Banzet P. et al.: Final report of phase II study of the nitrosourea fotemustine (S 10036) in 153 patients with disseminated malignant melanoma including patients with cerebral metastases. Cancer 66 (9): 1873-1878, 1990.
    • (1990) Cancer , vol.66 , Issue.9 , pp. 1873-1878
    • Jacquillat, C.1    Khayat, D.2    Banzet, P.3
  • 29
    • 0025690495 scopus 로고
    • Combination chemotherapy of dacarbazine and fotemustine in disseminated malignant melanoma. Experience of the French Study Group
    • Avril M.F., Bonneterre J., Delaunay M. et al.: Combination chemotherapy of dacarbazine and fotemustine in disseminated malignant melanoma. Experience of the French Study Group. Cancer Chemother. Pharmacol. 27: 81-84, 1990.
    • (1990) Cancer Chemother. Pharmacol. , vol.27 , pp. 81-84
    • Avril, M.F.1    Bonneterre, J.2    Delaunay, M.3
  • 30
    • 0027255607 scopus 로고
    • Long-term complete remissions in patients with disseminated melanoma treated by fotemustine and dacarbazine
    • Oliver V., Aliaga A., Lopez Lopez J.J. et al.: Long-term complete remissions in patients with disseminated melanoma treated by fotemustine and dacarbazine. Eur. J. Cancer 29A (2): 287, 1993.
    • (1993) Eur. J. Cancer , vol.29 A , Issue.2 , pp. 287
    • Oliver, V.1    Aliaga, A.2    Lopez Lopez, J.J.3
  • 31
    • 0026531374 scopus 로고
    • Fotemustine and DTIC combination in patients with disseminated malignant melanoma
    • Merimsky O., Inbar M., Chaitchik S.: Fotemustine and DTIC combination in patients with disseminated malignant melanoma. Am. J. Clin. Oncol. 15(1): 84-86, 1992.
    • (1992) Am. J. Clin. Oncol. , vol.15 , Issue.1 , pp. 84-86
    • Merimsky, O.1    Inbar, M.2    Chaitchik, S.3
  • 32
    • 0027501997 scopus 로고
    • Activity and unexpected lung toxicity of the sequential administration of two alkylating agents - Dacarbazine and fotemustine - In patients with melanoma
    • Gerard B., Aamdal S., Lee S.M. et al.: Activity and unexpected lung toxicity of the sequential administration of two alkylating agents - dacarbazine and fotemustine - in patients with melanoma. Eur. of Cancer 29A (5): 711-719, 1993.
    • (1993) Eur. of Cancer , vol.29 A , Issue.5 , pp. 711-719
    • Gerard, B.1    Aamdal, S.2    Lee, S.M.3
  • 33
    • 0026586976 scopus 로고
    • Sequential administration of decarbazine and fotemustine in patients with disseminated malignant melanoma - An effective combination with unexpected toxicity
    • Aamdal S., Gerard B., Bohman T., D'Incalci M.: Sequential administration of decarbazine and fotemustine in patients with disseminated malignant melanoma - an effective combination with unexpected toxicity. Eur. J. Cancer 28 (2/3): 447-450, 1992.
    • (1992) Eur. J. Cancer , vol.28 , Issue.2-3 , pp. 447-450
    • Aamdal, S.1    Gerard, B.2    Bohman, T.3    D'Incalci, M.4
  • 35
    • 0014836915 scopus 로고
    • Combination chemotherapy in malignant melanoma
    • Moon J.: Combination chemotherapy in malignant melanoma. Cancer 26: 468-473, 1970.
    • (1970) Cancer , vol.26 , pp. 468-473
    • Moon, J.1
  • 36
    • 0015348125 scopus 로고
    • Triple combination chemotherapy of disseminated melanoma
    • Cohen S.M., Greenspan E.M., Weiner M.J., Kabakow B.:Triple combination chemotherapy of disseminated melanoma. Cancer 29: 1489-1495, 1972.
    • (1972) Cancer , vol.29 , pp. 1489-1495
    • Cohen, S.M.1    Greenspan, E.M.2    Weiner, M.J.3    Kabakow, B.4
  • 37
    • 0017072030 scopus 로고
    • DTIC (NSC 45388) and combination therapy for melanoma I. Studies with DTIC, BCNU (NSC 409962), CCNU (NSC 79037), vincristine (NSC 67574), and hydroxyurea (NSC 32065)
    • Carter R.D., Krementz E.T., Hill G.J. et al.: DTIC (NSC 45388) and combination therapy for melanoma I. Studies with DTIC, BCNU (NSC 409962), CCNU (NSC 79037), vincristine (NSC 67574), and hydroxyurea (NSC 32065). Cancer Treat. Rep. 60: 601-609, 1976.
    • (1976) Cancer Treat. Rep. , vol.60 , pp. 601-609
    • Carter, R.D.1    Krementz, E.T.2    Hill, G.J.3
  • 38
    • 0021325538 scopus 로고
    • Dimethyl triazeno imidazole carboxamide and combination therapy for melanoma IV. Late results after complete response to chemotherapy (Central Oncology Group Protocols 7130, 7131, and 7131A)
    • Hill G.J., Krementz E.T., Hill H.Z.: Dimethyl triazeno imidazole carboxamide and combination therapy for melanoma IV. Late results after complete response to chemotherapy (Central Oncology Group Protocols 7130, 7131, and 7131A). Cancer 53: 1299-1305, 1984.
    • (1984) Cancer , vol.53 , pp. 1299-1305
    • Hill, G.J.1    Krementz, E.T.2    Hill, H.Z.3
  • 39
    • 0017126181 scopus 로고
    • DTIC (NSC-45388) studies in the Southwest Oncology Group
    • Costanzi J.J.: DTIC (NSC-45388) studies in the Southwest Oncology Group. Cancer Treat. Rep. 60: 189-192, 1976.
    • (1976) Cancer Treat. Rep. , vol.60 , pp. 189-192
    • Costanzi, J.J.1
  • 40
    • 0017331185 scopus 로고
    • Bischloroethyl nitrosourea, vincristine, dimethyl triazeno imidazole carboxamide and chlorpromazine combination chemotherapy in disseminated malignant melanoma
    • McKelvey E.M., Luce J.K., Vaitkevicius K. et al.: Bischloroethyl nitrosourea, vincristine, dimethyl triazeno imidazole carboxamide and chlorpromazine combination chemotherapy in disseminated malignant melanoma. Cancer 39: 5-10, 1977.
    • (1977) Cancer , vol.39 , pp. 5-10
    • McKelvey, E.M.1    Luce, J.K.2    Vaitkevicius, K.3
  • 42
    • 0019995517 scopus 로고
    • Combination chemotherapy plus BCG in the treatment of disseminated malignant melanoma: A Southwest Oncology Group study
    • Costanzi J.J., Al-Sarraf M., Groppe C. et al.: Combination chemotherapy plus BCG in the treatment of disseminated malignant melanoma: a Southwest Oncology Group study. Med. Pediatr. Oncol. 10: 251-258, 1982.
    • (1982) Med. Pediatr. Oncol. , vol.10 , pp. 251-258
    • Costanzi, J.J.1    Al-Sarraf, M.2    Groppe, C.3
  • 43
    • 0017055931 scopus 로고
    • Combination chemotherapy with three marginally effective agents, CCNU, vincristine, and bleomycin in the treatment of stage III melanoma
    • De Wasch G., Bernheim J., Michel J., Lejeune F., Kenis V.: Combination chemotherapy with three marginally effective agents, CCNU, vincristine, and bleomycin in the treatment of stage III melanoma. Cancer Treat. Rep. 60: 1273-1276, 1976.
    • (1976) Cancer Treat. Rep. , vol.60 , pp. 1273-1276
    • De Wasch, G.1    Bernheim, J.2    Michel, J.3    Lejeune, F.4    Kenis, V.5
  • 44
    • 0019204729 scopus 로고
    • DTIC, CCNU, bleomycin and vicristine (BOLD) in metastatic melanoma
    • Seigler H.F., Lucas V.S. Jr., Pickett N.J., Huang A.T.: DTIC, CCNU, bleomycin and vicristine (BOLD) in metastatic melanoma. Cancer 46: 2346-2348, 1980.
    • (1980) Cancer , vol.46 , pp. 2346-2348
    • Seigler, H.F.1    Lucas Jr., V.S.2    Pickett, N.J.3    Huang, A.T.4
  • 45
    • 1642592950 scopus 로고
    • The limited role of BOLD chemotherapy for disseminated malignant melanoma
    • Abstr
    • Ahn S.S., Giuliano A., Kaiser L. et al.: The limited role of BOLD chemotherapy for disseminated malignant melanoma. Proceedings Am. Soc. Clin. Oncol. 2: 228 (Abstr), 1983.
    • (1983) Proceedings Am. Soc. Clin. Oncol. , vol.2 , pp. 228
    • Ahn, S.S.1    Giuliano, A.2    Kaiser, L.3
  • 47
    • 0021955601 scopus 로고
    • The use of BELD combination chemotherapy (bleomycin, vindesine, CCNU, and DTIC) in advanced malignant melanoma
    • Young D.W., Lever R.S., English J.S.C., McKie R.M.: The use of BELD combination chemotherapy (bleomycin, vindesine, CCNU, and DTIC) in advanced malignant melanoma. Cancer 55: 1879-1881, 1985.
    • (1985) Cancer , vol.55 , pp. 1879-1881
    • Young, D.W.1    Lever, R.S.2    English, J.S.C.3    McKie, R.M.4
  • 48
    • 0023876860 scopus 로고
    • Bleomycin, vincristine, lomustine, and DTIC chemotherapy for metastatic melanoma
    • York R.M., Foltz A.T.: Bleomycin, vincristine, lomustine, and DTIC chemotherapy for metastatic melanoma. Cancer 61: 2183-2186, 1988.
    • (1988) Cancer , vol.61 , pp. 2183-2186
    • York, R.M.1    Foltz, A.T.2
  • 49
    • 0024515901 scopus 로고
    • Chemotherapy of disseminated melanoma with bleomycin, vincristine, CCNU, and DTIC (BOLD regimen)
    • The Prudente Foundation Melanoma Study Group.: Chemotherapy of disseminated melanoma with bleomycin, vincristine, CCNU, and DTIC (BOLD regimen). Cancer 63: 1676-1680, 1989.
    • (1989) Cancer , vol.63 , pp. 1676-1680
  • 50
    • 0027082482 scopus 로고
    • A promising interferon plus four-drug chemotherapy regimen for metastatic melanoma
    • Pyrhönen S., Hahka-Kemppinen M. and Muhonen T.: A promising interferon plus four-drug chemotherapy regimen for metastatic melanoma. J. Clin. Oncol. 10: 1919-1926, 1992.
    • (1992) J. Clin. Oncol. , vol.10 , pp. 1919-1926
    • Pyrhönen, S.1    Hahka-Kemppinen, M.2    Muhonen, T.3
  • 51
    • 0030959126 scopus 로고    scopus 로고
    • Chemoimniunotherapy withe bleomycin, vincristine, lomustine, dacarbazine (BOLD) plus interferon a for metastatic melanoma: A multicentre phase II study
    • Punt C.J.A., van Herpen C.M.L., Jansen R.L.H., Vreugdenhil G., Muller E.W., De Mulder P.H.M.: Chemoimniunotherapy withe bleomycin, vincristine, lomustine, dacarbazine (BOLD) plus interferon a for metastatic melanoma: a multicentre phase II study. Br. J. Cancer 76 (2): 266-269, 1997.
    • (1997) Br. J. Cancer , vol.76 , Issue.2 , pp. 266-269
    • Punt, C.J.A.1    Van Herpen, C.M.L.2    Jansen, R.L.H.3    Vreugdenhil, G.4    Muller, E.W.5    De Mulder, P.H.M.6
  • 52
    • 0030981749 scopus 로고    scopus 로고
    • BOLD + Interferon in the treatment of metastatic uveal melanoma: First report of active systemic therapy
    • Nathan F.E., Berd D., Sato T. et al.: BOLD + Interferon in the treatment of metastatic uveal melanoma: first report of active systemic therapy. J. Exp. Clin. Cancer Res. 16 (2): 201-208, 1997.
    • (1997) J. Exp. Clin. Cancer Res. , vol.16 , Issue.2 , pp. 201-208
    • Nathan, F.E.1    Berd, D.2    Sato, T.3
  • 53
    • 0022588102 scopus 로고
    • Treatment of metastatic malignant melanoma with vinblastine, dacarbazine and cisplatin: A report from the Cancer and Leukemia Group B
    • Carey R.W., Anderson J.R., Green M., Ellisson R.R., Nathanson L., Kennedy B.J.: Treatment of metastatic malignant melanoma with vinblastine, dacarbazine and cisplatin: a report from the Cancer and Leukemia Group B. Cancer Treat. Rep. 70 (3): 329-331, 1986.
    • (1986) Cancer Treat. Rep. , vol.70 , Issue.3 , pp. 329-331
    • Carey, R.W.1    Anderson, J.R.2    Green, M.3    Ellisson, R.R.4    Nathanson, L.5    Kennedy, B.J.6
  • 54
    • 0024448792 scopus 로고
    • A prospective evaluation of a triple-drug regimen containing cisplatin, vinblastine, and dacarbazine (CVD) for metastatic melanoma
    • Legha S.S., Ring S., Papadopoulos N, Plager C., Chawla S., Benjamin R.: A prospective evaluation of a triple-drug regimen containing cisplatin, vinblastine, and dacarbazine (CVD) for metastatic melanoma. Cancer 64: 2024-2029, 1989.
    • (1989) Cancer , vol.64 , pp. 2024-2029
    • Legha, S.S.1    Ring, S.2    Papadopoulos, N.3    Plager, C.4    Chawla, S.5    Benjamin, R.6
  • 55
    • 0000022334 scopus 로고
    • Cisplatin (C), Vinblastine (V), and dacarbazine (D) (CVD) versus dacarbazine alone in metastatic melanoma: Preliminary results of a phase III Cancer Community Oncology Program (CCOP) trial
    • Abstr
    • Buzaid A.C., Legha S.S., Winn R. et al.: Cisplatin (C), Vinblastine (V), and dacarbazine (D) (CVD) versus dacarbazine alone in metastatic melanoma: preliminary results of a phase III Cancer Community Oncology Program (CCOP) trial. Proceedings Am. Soc. Clin. Oncol. 12: 389 (Abstr), 1993.
    • (1993) Proceedings Am. Soc. Clin. Oncol. , vol.12 , pp. 389
    • Buzaid, A.C.1    Legha, S.S.2    Winn, R.3
  • 57
    • 0021275104 scopus 로고
    • Vindesine in patients with metastatic malignant melanoma: A Southwest Oncology Group Study
    • Quagliana J.M., Stephens R.L., Baker L.H. et al.: Vindesine in patients with metastatic malignant melanoma: a Southwest Oncology Group Study. J. Clin. Oncol. 2: 316-319, 1984.
    • (1984) J. Clin. Oncol. , vol.2 , pp. 316-319
    • Quagliana, J.M.1    Stephens, R.L.2    Baker, L.H.3
  • 58
    • 0023521482 scopus 로고
    • Dacarbazine, vindesine, and cisplatin combination chemotherapy in advanced malignant melanoma: A phase II study
    • Gundersen S.: Dacarbazine, vindesine, and cisplatin combination chemotherapy in advanced malignant melanoma: a phase II study. Cancer Treat. Rep. 71 (11): 997-999, 1987.
    • (1987) Cancer Treat. Rep. , vol.71 , Issue.11 , pp. 997-999
    • Gundersen, S.1
  • 59
    • 0023735135 scopus 로고
    • Combination of cisplatin, vindesine, and dacarbazine in advanced malignant melanoma. A phase II study of the EORTC malignant melanoma cooperative group
    • Verschraegen C.F., Kleeberg U.R., Mulder J. et al.: Combination of cisplatin, vindesine, and dacarbazine in advanced malignant melanoma. A phase II study of the EORTC malignant melanoma cooperative group. Cancer 62: 1061-1065, 1988.
    • (1988) Cancer , vol.62 , pp. 1061-1065
    • Verschraegen, C.F.1    Kleeberg, U.R.2    Mulder, J.3
  • 60
    • 17344382437 scopus 로고    scopus 로고
    • Dacarbazine-vindesine versus dacarbazine-vindesine-cisplatin in disseminated malignant melanoma. A randomized phase III trial
    • Jungnelius U., Ringborg V., Aamdal S. et al.: Dacarbazine-vindesine versus dacarbazine-vindesine-cisplatin in disseminated malignant melanoma. A randomized phase III trial. Eur. J. Cancer 34(9): 1368-1374, 1998.
    • (1998) Eur. J. Cancer , vol.34 , Issue.9 , pp. 1368-1374
    • Jungnelius, U.1    Ringborg, V.2    Aamdal, S.3
  • 61
    • 0017195219 scopus 로고
    • Estrogen receptor in human malignant melanoma
    • Fisher R.I., Neifeld J.P., Lippman M.E.: Estrogen receptor in human malignant melanoma. Lancet 2: 337-338, 1976.
    • (1976) Lancet , vol.2 , pp. 337-338
    • Fisher, R.I.1    Neifeld, J.P.2    Lippman, M.E.3
  • 64
  • 65
    • 0021702431 scopus 로고
    • Combination chemotherapy with cisplatin, carmustine, dacarbazine and tamoxifen in metastatic melanoma
    • Del Prete S.A., Maurer L.H., O'Donnell J., Forcier R.J., Le Marbre P.: Combination chemotherapy with cisplatin, carmustine, dacarbazine and tamoxifen in metastatic melanoma. Cancer Treat. Rep. 68: 1403-1405, 1984.
    • (1984) Cancer Treat. Rep. , vol.68 , pp. 1403-1405
    • Del Prete, S.A.1    Maurer, L.H.2    O'Donnell, J.3    Forcier, R.J.4    Le Marbre, P.5
  • 66
    • 0023217283 scopus 로고
    • Combination chemotherapy and hormonal therapy in the treatment of malignant melanoma
    • McClay E.F., Mastrangelo M.J., Bellet R.E. et al.: Combination chemotherapy and hormonal therapy in the treatment of malignant melanoma. Cancer Treat. Rep. 71 (5): 465-469, 1987.
    • (1987) Cancer Treat. Rep. , vol.71 , Issue.5 , pp. 465-469
    • McClay, E.F.1    Mastrangelo, M.J.2    Bellet, R.E.3
  • 67
    • 0024504718 scopus 로고
    • The importance of tamoxifen to a cisplatin containing regimen in the treatment of metastatic melanoma
    • McClay E.F., Mastrangelo M.J., Sprandio J.D. et al.: The importance of tamoxifen to a cisplatin containing regimen in the treatment of metastatic melanoma. Cancer 63: 1292-1295, 1989.
    • (1989) Cancer , vol.63 , pp. 1292-1295
    • McClay, E.F.1    Mastrangelo, M.J.2    Sprandio, J.D.3
  • 69
    • 0026551390 scopus 로고
    • Effective combination chemo/hormonal therapy for malignant melanoma: Experience with three consecutive trials
    • McClay E.F., Mastrangelo M.J., Berd D. et al.: Effective combination chemo/hormonal therapy for malignant melanoma: experience with three consecutive trials. Int. J. Cancer 50: 553-556, 1992.
    • (1992) Int. J. Cancer , vol.50 , pp. 553-556
    • McClay, E.F.1    Mastrangelo, M.J.2    Berd, D.3
  • 70
    • 0027155344 scopus 로고
    • Therapy for metastatic melanoma: Effective combination of dacarbazine, carmustine, cisplatin and tamoxifen
    • Fierro M.T., Bertero M., Novelli M. et al.: Therapy for metastatic melanoma: effective combination of dacarbazine, carmustine, cisplatin and tamoxifen. Melanoma Res. 3: 127-131, 1993.
    • (1993) Melanoma Res. , vol.3 , pp. 127-131
    • Fierro, M.T.1    Bertero, M.2    Novelli, M.3
  • 71
    • 0027189804 scopus 로고
    • Chemotherapy for stage 4 melanoma: A three-year experience with cisplatin, DTIC, BC-NU, and tamoxifen
    • Reintgen D. and Saba H.: Chemotherapy for stage 4 melanoma: a three-year experience with cisplatin, DTIC, BC-NU, and tamoxifen. Semin. Surg. Oncol. 9: 251-255, 1993.
    • (1993) Semin. Surg. Oncol. , vol.9 , pp. 251-255
    • Reintgen, D.1    Saba, H.2
  • 72
    • 0013689413 scopus 로고
    • Dacarbazine (D), cisplatin (C), and carmustine (B), +/- Tamoxifen (T) in the treatment of patients (pts) with metastatic melanoma (MM): Results of 5-year follow-up
    • Abstr
    • Lattanzi S.C., Tosteson T., Maurer L.H. et al.: Dacarbazine (D), cisplatin (C), and carmustine (B), +/-tamoxifen (T) in the treatment of patients (pts) with metastatic melanoma (MM): results of 5-year follow-up. Proceedings Am. Soc. Clin. Oncol. 12:390 (Abstr), 1993.
    • (1993) Proceedings Am. Soc. Clin. Oncol. , vol.12 , pp. 390
    • Lattanzi, S.C.1    Tosteson, T.2    Maurer, L.H.3
  • 73
    • 0029097550 scopus 로고
    • Dacarbazine, cisplatin, and carmustine, with or without tamoxifen for metastatic melanoma: 5-year follow-up
    • Lattanzi S.C., Tosteson T., Chertoff J. et al.: Dacarbazine, cisplatin, and carmustine, with or without tamoxifen for metastatic melanoma: 5-year follow-up. Melanoma Res. 5: 365-369, 1995.
    • (1995) Melanoma Res. , vol.5 , pp. 365-369
    • Lattanzi, S.C.1    Tosteson, T.2    Chertoff, J.3
  • 74
    • 0026625695 scopus 로고
    • Treatment of metastatic malignant melanoma with dacarbazine plus tamoxifen
    • Cocconi G., Bella M., Calabresi F. et al.: Treatment of metastatic malignant melanoma with dacarbazine plus tamoxifen. New Engl. J. Med. 327 (8): 516-523, 1992.
    • (1992) New Engl. J. Med. , vol.327 , Issue.8 , pp. 516-523
    • Cocconi, G.1    Bella, M.2    Calabresi, F.3
  • 75
    • 0026664267 scopus 로고
    • Disseminated melanoma: Is there a new standard therapy
    • Guerry D.I.V., Schucter L.M.: Disseminated melanoma: is there a new standard therapy. New Engl. J. Med. 327: 560-561, 1992.
    • (1992) New Engl. J. Med. , vol.327 , pp. 560-561
    • Guerry, D.I.V.1    Schucter, L.M.2
  • 77
    • 0028301918 scopus 로고
    • Tamoxifen: Is it useful in the treatment of patients with metastatic melanoma
    • McClay E.F. and McClay M.E.T.: Tamoxifen: is it useful in the treatment of patients with metastatic melanoma. J. Clin. Oncol. 12: 617-626, 1994.
    • (1994) J. Clin. Oncol. , vol.12 , pp. 617-626
    • McClay, E.F.1    McClay, M.E.T.2
  • 78
    • 0344538063 scopus 로고
    • Carboplatin and dacarbazine plus/minus tamoxifen for metastatic melanoma
    • Abstr
    • Ferri W., Kirkwood J.M., Vlock D. et al.: Carboplatin and dacarbazine plus/minus tamoxifen for metastatic melanoma. Proceedings Am. Soc. Clin. Oncol. 12: 396 (Abstr), 1993.
    • (1993) Proceedings Am. Soc. Clin. Oncol. , vol.12 , pp. 396
    • Ferri, W.1    Kirkwood, J.M.2    Vlock, D.3
  • 79
    • 8944261598 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled trial comparing the response rates of carmustine, dacarbazine, and cisplatin with and without tamoxifen in patients with metastatic melanoma
    • Rusthoven J.J., Quirt I.C., Iscoe N.A. et al.: Randomized, double-blind, placebo-controlled trial comparing the response rates of carmustine, dacarbazine, and cisplatin with and without tamoxifen in patients with metastatic melanoma. J. Clin. Oncol. 14: 2083-2090, 1996.
    • (1996) J. Clin. Oncol. , vol.14 , pp. 2083-2090
    • Rusthoven, J.J.1    Quirt, I.C.2    Iscoe, N.A.3
  • 80
    • 0031805725 scopus 로고    scopus 로고
    • Phase III trial of dacarbazine versus dacarbazine with interferon alfa-2b versus dacarbazine with tamoxifen versus dacarbazine with interferon alfa-2b and tamoxifen in patients with metastatic malignant melanoma: An Eastern Cooperative Oncology Group Study
    • Falkson C.I., Ibrahim J., Kirkwood J.M., Coates A.S., Atkins M.B., Blum R.H.: Phase III trial of dacarbazine versus dacarbazine with interferon alfa-2b versus dacarbazine with tamoxifen versus dacarbazine with interferon alfa-2b and tamoxifen in patients with metastatic malignant melanoma: an Eastern Cooperative Oncology Group Study. J. Clin. Oncol. 16: 1743-1751, 1998.
    • (1998) J. Clin. Oncol. , vol.16 , pp. 1743-1751
    • Falkson, C.I.1    Ibrahim, J.2    Kirkwood, J.M.3    Coates, A.S.4    Atkins, M.B.5    Blum, R.H.6
  • 81
    • 0003229859 scopus 로고    scopus 로고
    • A phase III multicenter randomized trial of DTIC, cisplatin, BCNU and tamoxifen versus DTIC alone in patients with metastatic melanoma
    • Abstr
    • Saxman S.B., Meyers M.L., Chapman P.B. et al.: A phase III multicenter randomized trial of DTIC, cisplatin, BCNU and tamoxifen versus DTIC alone in patients with metastatic melanoma. Proceedings Am. Soc. Clin. Oncol. 18: 536 (Abstr), 1999.
    • (1999) Proceedings Am. Soc. Clin. Oncol. , vol.18 , pp. 536
    • Saxman, S.B.1    Meyers, M.L.2    Chapman, P.B.3
  • 82
    • 0023605735 scopus 로고
    • Antitumor activity and pharmacokinetics in mice of 8-carbamoyl-3-methylimidazol (5,1-d)1,2,3,5-tetrazin-4 (3H)- One (CCRG 81045; M§B 39831) a novel drug with potential as an alternative to dacarbazine
    • Stevens M.F.G., Hickman J.A., Langdon S.P. et al.: Antitumor activity and pharmacokinetics in mice of 8-carbamoyl-3-methylimidazol (5,1-d)1,2,3,5-tetrazin-4 (3H)-one (CCRG 81045; M§B 39831) a novel drug with potential as an alternative to dacarbazine. Cancer Res. 47: 5846-5852, 1987.
    • (1987) Cancer Res. , vol.47 , pp. 5846-5852
    • Stevens, M.F.G.1    Hickman, J.A.2    Langdon, S.P.3
  • 83
    • 0028944359 scopus 로고
    • Cancer Research Campaign phase II trial of temozolomide in metastatic melanoma
    • Bleehen N.M., Newlands E.S., Lee S.M. et al.: Cancer Research Campaign phase II trial of temozolomide in metastatic melanoma. J. Clin. Oncol. 13: 910-913, 1995.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 910-913
    • Bleehen, N.M.1    Newlands, E.S.2    Lee, S.M.3
  • 84
    • 0023689603 scopus 로고
    • Metabolism of SR 4233 by chinese hamster ovary cells: Basis of selective hypoxic cytotoxicity
    • Baker M., Zeman E., Hirst V., Brown J.: Metabolism of SR 4233 by chinese hamster ovary cells: basis of selective hypoxic cytotoxicity. Cancer Res. 48: 5947-5952, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 5947-5952
    • Baker, M.1    Zeman, E.2    Hirst, V.3    Brown, J.4
  • 85
    • 0030913953 scopus 로고    scopus 로고
    • Phase II trial of tirapazamine combined with cisplatin in chemotherapy of advanced malignant melanoma
    • Bedikian A.Y., Legha S.S., Eton O. et al: Phase II trial of tirapazamine combined with cisplatin in chemotherapy of advanced malignant melanoma. Ann. Oncol. 8: 363-367, 1997.
    • (1997) Ann. Oncol. , vol.8 , pp. 363-367
    • Bedikian, A.Y.1    Legha, S.S.2    Eton, O.3
  • 86
  • 88
    • 1642623996 scopus 로고    scopus 로고
    • Phase II trial of taxol and DTIC with filgrastim administration in advanced malignant melanoma (MM)
    • Abstr
    • Feun L.G., Savaraj N., Schwartz M. et al.: Phase II trial of taxol and DTIC with filgrastim administration in advanced malignant melanoma (MM). Proceedings Am. Soc. Clin. Oncol. 16: 505 (Abstr), 1997.
    • (1997) Proceedings Am. Soc. Clin. Oncol. , vol.16 , pp. 505
    • Feun, L.G.1    Savaraj, N.2    Schwartz, M.3
  • 89
    • 0032944017 scopus 로고    scopus 로고
    • The chemoresistance of human malignant melanoma: An update
    • Serrone L., Hersey P.: The chemoresistance of human malignant melanoma: an update. Melanoma Res. 9 (1): 51-58, 1999.
    • (1999) Melanoma Res. , vol.9 , Issue.1 , pp. 51-58
    • Serrone, L.1    Hersey, P.2
  • 90
    • 0030864875 scopus 로고    scopus 로고
    • Nitric oxide-mediated apoptosis of k-1735 melanoma cells is associated with downregulation of bcl-2
    • Xie K., Wang Y., Huang S. et al.: Nitric oxide-mediated apoptosis of k-1735 melanoma cells is associated with downregulation of bcl-2. Oncogene 15: 771-779, 1997.
    • (1997) Oncogene , vol.15 , pp. 771-779
    • Xie, K.1    Wang, Y.2    Huang, S.3
  • 91
    • 0031907428 scopus 로고    scopus 로고
    • Bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice
    • Jansen B., Schlagbauer-Wadl H., Brown B.D. et al.: Bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice. Nature Med. 4: 232-234, 1998.
    • (1998) Nature Med. , vol.4 , pp. 232-234
    • Jansen, B.1    Schlagbauer-Wadl, H.2    Brown, B.D.3
  • 92
    • 0025058101 scopus 로고
    • Chemotherapy for malignant melanoma: Combinations and high doses produce more responses without survival benefit
    • Lakhani S., Selby P., Bliss J.M., Perren T.J., Gore M.E., M.c Elwain T.J.: Chemotherapy for malignant melanoma: combinations and high doses produce more responses without survival benefit. Br. J. Cancer 61: 330-334, 1990.
    • (1990) Br. J. Cancer , vol.61 , pp. 330-334
    • Lakhani, S.1    Selby, P.2    Bliss, J.M.3    Perren, T.J.4    Gore, M.E.5    Mc. Elwain, T.J.6
  • 93
    • 0024490334 scopus 로고
    • Complete responses and long-term survivals after systemic chemotherapy for patients with advanced malignant melanoma
    • Ahmann D.L., Creagan E.T., Hahn R.G., Edmonson J.H., Bisel H.F., Schaid D.J.: Complete responses and long-term survivals after systemic chemotherapy for patients with advanced malignant melanoma. Cancer 63: 224-227, 1989.
    • (1989) Cancer , vol.63 , pp. 224-227
    • Ahmann, D.L.1    Creagan, E.T.2    Hahn, R.G.3    Edmonson, J.H.4    Bisel, H.F.5    Schaid, D.J.6
  • 94
    • 0021320381 scopus 로고
    • Randomized phase III trial of vinblastine, bleomycin and cis-dichlorodiammineplatinum versus dacarbazine in malignant melanoma
    • Luikart S.D., Kennealey G.T., Kirkwood J.M.: Randomized phase III trial of vinblastine, bleomycin and cis-dichlorodiammineplatinum versus dacarbazine in malignant melanoma. J. Clin. Oncol. 2: 164-168, 1984.
    • (1984) J. Clin. Oncol. , vol.2 , pp. 164-168
    • Luikart, S.D.1    Kennealey, G.T.2    Kirkwood, J.M.3
  • 95
    • 0028934745 scopus 로고
    • Combination chemotherapy of metastatic melanoma
    • Berd D., Mastrangelo M.J.: Combination chemotherapy of metastatic melanoma. J. Clin. Oncol. 13 (3): 796, 1995.
    • (1995) J. Clin. Oncol. , vol.13 , Issue.3 , pp. 796
    • Berd, D.1    Mastrangelo, M.J.2
  • 97
    • 0004189406 scopus 로고
    • Interleukih-2 for the treatment of advanced melanoma
    • Sparano J.A., Dutcher J.P.: Interleukih-2 for the treatment of advanced melanoma. Hematol. Oncol. Ann. 1: 279-285, 1993.
    • (1993) Hematol. Oncol. Ann. , vol.1 , pp. 279-285
    • Sparano, J.A.1    Dutcher, J.P.2
  • 98
    • 0030030641 scopus 로고    scopus 로고
    • Evaluation of interleukin-2 administered by continuous infusion in patients with metastatic melanoma
    • Legha S.S., Gianan M.A., Plager C., Eton D.E., Papadopoulos N.E.J.: Evaluation of interleukin-2 administered by continuous infusion in patients with metastatic melanoma. Cancer 77: 89-96, 1996.
    • (1996) Cancer , vol.77 , pp. 89-96
    • Legha, S.S.1    Gianan, M.A.2    Plager, C.3    Eton, D.E.4    Papadopoulos, N.E.J.5
  • 99
    • 0029027251 scopus 로고
    • Combination therapy with interferon alfa-2a and interleukin-2 for the treatment of metastatic cancer
    • Marincola F.M., White D.E., Wise A.P., Rosenberg S.A.: Combination therapy with interferon alfa-2a and interleukin-2 for the treatment of metastatic cancer. J. Clin. Oncol. 13: 1110-1122, 1995.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 1110-1122
    • Marincola, F.M.1    White, D.E.2    Wise, A.P.3    Rosenberg, S.A.4
  • 100
    • 0027315222 scopus 로고
    • Interferon a and interleukin-2 in the treatment of malignant melanoma: A comparison of two phase II trials
    • Keilholz U., Scheibenbogen C., Tilgen W. et al.: Interferon a and interleukin-2 in the treatment of malignant melanoma: a comparison of two phase II trials. Cancer 72: 607-614, 1993.
    • (1993) Cancer , vol.72 , pp. 607-614
    • Keilholz, U.1    Scheibenbogen, C.2    Tilgen, W.3
  • 101
    • 0026734180 scopus 로고
    • Sequential chemoimmunotherapy in the treatment of metastatic melanoma
    • Richards J.M., Mehta N., Ramming K., Skosey P:. Sequential chemoimmunotherapy in the treatment of metastatic melanoma. J. Clin. Oncol. 10: 1338-1343, 1992.
    • (1992) J. Clin. Oncol. , vol.10 , pp. 1338-1343
    • Richards, J.M.1    Mehta, N.2    Ramming, K.3    Skosey, P.4
  • 102
    • 0027486041 scopus 로고
    • Sequential chemoimmunotherapy with cisplatin, interleukin-2 and interferon alfa-2a for metastatic melanoma
    • Khayat D., Borel C., Tourani J.M. et al.: Sequential chemoimmunotherapy with cisplatin, interleukin-2 and interferon alfa-2a for metastatic melanoma. J. Clin. Oncol. 12: 2173-2180, 1993.
    • (1993) J. Clin. Oncol. , vol.12 , pp. 2173-2180
    • Khayat, D.1    Borel, C.2    Tourani, J.M.3
  • 103
    • 0031805726 scopus 로고    scopus 로고
    • Development of a biochemotherapy regimen with concurrent administration of cisplatin, vinblastine, dacarbazine, interferon alfa and interIeukin-2 for patients with metastatic melanoma
    • Legha S.S., Ring S., Eton O. et al.: Development of a biochemotherapy regimen with concurrent administration of cisplatin, vinblastine, dacarbazine, interferon alfa and interIeukin-2 for patients with metastatic melanoma. J. Clin. Oncol. 16: 1752-1759, 1998.
    • (1998) J. Clin. Oncol. , vol.16 , pp. 1752-1759
    • Legha, S.S.1    Ring, S.2    Eton, O.3
  • 104
    • 0031406876 scopus 로고    scopus 로고
    • Recombinant interleukin-2 based treatment for advanced melanoma: The experience of the EORTC-Melanoma-Cooperative Group
    • Keilholz U., Stoter G., Punt C.J., Scheibenbogen C., Lejeune F., Eggermont A.M.: Recombinant interleukin-2 based treatment for advanced melanoma: the experience of the EORTC-Melanoma-Cooperative Group. Cancer J. Sci. Am. 3: S22-S28, 1997.
    • (1997) Cancer J. Sci. Am. , vol.3
    • Keilholz, U.1    Stoter, G.2    Punt, C.J.3    Scheibenbogen, C.4    Lejeune, F.5    Eggermont, A.M.6
  • 105
    • 0031718717 scopus 로고    scopus 로고
    • Results of interleukin-2 based treatment in advanced melanoma: A case record-based analysis of 631 patients
    • Keilholz U., Conradt C., Legha S.S. et al.: Results of interleukin-2 based treatment in advanced melanoma: a case record-based analysis of 631 patients. J. Clin. Oncol. 16: 2921-2929, 1998.
    • (1998) J. Clin. Oncol. , vol.16 , pp. 2921-2929
    • Keilholz, U.1    Conradt, C.2    Legha, S.S.3


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