Signaling mechanisms of the D3 dopamine receptor

Journal of Receptors and Signal Transduction

Volumn 24, Issue 3, 2004, Pages 117-130

  Ahlgren Beckendorf, Joy A ^a   Levant, Beth ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

Adenylate cyclase; Calcium channel; Dopamine D3 receptor; G proteins; Kinase; Potassium channel

Indexed keywords

ADENYLATE CYCLASE; CALCIUM; CALCIUM CHANNEL; DOPAMINE 3 RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; POTASSIUM; POTASSIUM CHANNEL; PROTEIN C FOS; PROTEIN KINASE; DOPAMINE 2 RECEPTOR; DRD3 PROTEIN, HUMAN;

ANIMAL CELL; BRAIN; CELL CULTURE; CONFERENCE PAPER; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; ION CURRENT; NERVE CELL; NONHUMAN; PROTEIN EXPRESSION; RECEPTOR AFFINITY; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; ANIMAL; METABOLISM; REVIEW;

ANIMALIA;

ADENYLATE CYCLASE; ANIMALS; BRAIN; CALCIUM CHANNELS; GTP-BINDING PROTEINS; HUMANS; POTASSIUM CHANNELS; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-FOS; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D3; SIGNAL TRANSDUCTION;

EID: 4944231708     PISSN: 10799893     EISSN: 15324281     Source Type: Journal    
DOI: 10.1081/RRS-200029953     Document Type: Conference Paper

References (92)

1. 3 receptor in schizophrenia and in antipsychotic drug actions. Brain Res Brain Res Rev 2000; 31(2-3):277-287.
2. 3 receptor as a therapeutic target for antipsychotic and antiparkinsonian drugs. Pharmacol Ther 2001; 90(2-3):231-259.
3. 3 dopamine receptor and substance dependence. J Addict Dis 2001; 20(3):19-32.
4. 3 dopamine receptor, behavioral sensitization, and psychosis. Neurosci Biobehav Rev 2001; 25(5):427-443.
5. 3 Receptors. Relevance for the drug treatment of Parkinson's disease. CNS Drugs 1999; 12(6):391-402.
6. 3) as a target for neuroleptics. Nature 1990; 347(6289):146-151.
7. 3 humain et idetification de son chromosome. CR Acad Sci III 1990; 311(13):501-508.
8. 2-like dopamine receptors. Biochem J 1992; 287(Pt 1):277-282.
9. 3 receptors. Synapse 1993; 14(1):90-95.
10. 3 receptors. Eur J Pharmacol 1995; 278(3):243-247.
11. 3 dopamine receptor affinity of dopaminergic compounds in rat brain. Life Sci 1998; 62(20):1825-1831.
12. 3 dopamine receptor: neurobiology and potential clinical relevance. Pharmacol Rev 1997; 49(3):231-252.
13. 3 receptor mRNA in the rat brain using in situ hybridization histochemistry: comparison with dopamine D2 receptor mRNA. Brain Res 1991; 564(2):203-219.
14. 2-like dopamine receptors in rat brain. J Pharmacol Exp Ther 1992; 262(3):929-935.
15. 3H]hydroxy-N,N-di-n-propyl-2-aminotetralin. Proc Natl Acad Sci USA 1992; 89(17):8155-8159.
16. 3 dopamine receptor, in rat brain: a receptor binding and quantitative autoradiographic study. Neuropsychopharmacology 1998; 18(4):305-316.
17. 3 receptor in the rat cerebellar cortex: a light microscope autoradiographic study. Neurosci Lett 1995; 190(3):163-166.
18. 3 dopamine receptors in rat spinal cord: implications for sensory and motor function. Neurosci Lett 2001; 303(1):9-12.
19. 3 dopamine receptors in the brains of several mammalian species. Brain Res 1998; 800(2):269-274.
20. 3H]7-hydroxy-N,N-di-n-propyl-2-aminotetralin. Brain Res 1994; 648(2):222-228.
21. 3 receptor mRNA and binding sites in human brain. Brain Res. Mol. Brain Res 1993; 18(1-2):187-192.
22. 2 receptors to mesostriatal regions of human forebrain. Proc Natl Acad Sci USA 1994; 91(23):11271-11275.
23. 2-family receptor distribution in human postmortem tissue: an autoradiographic study. Neuroreport 1995; 6(18):2505-2512.
24. 3 dopamine receptor mRNA is widely expressed in the human brain. Brain Res 1998; 779(1-2):58-74.
25. Meador-Woodruff JH, Damask SP, Wang J, Haroutunian V, Davis KL, Watson SJ. Dopamine receptor mRNA expression in human striatum and neocortex. Neuropsychopharmacology 1996; 15(1):17-29.
26. 2 receptor expressing neurons. Neuropsychopharmacology 1999; 20(1):60-80.
27. 3 dopamine receptor in cellular and organismal function. Psychopharmacology (Berl) 1998; 135(1):1-16.
28. Kenakin T. The classification of seven transmembrane receptor in recombinant expression systems. Pharmacol Rev 1996; 48(3):413-463.
29. Wieland T, Jakobs KH. Measurements of receptor-stimualted guanosine 5′-o-(γ-thio) triphosphate binding by G proteins. Methods Enzymol 1994; 237:3-13.
30. 3 dopamine receptor. Neurosci Lett 1997; 226(2):91-94.
31. 35S-binding. J Pharmacol Exp Ther 1998; 285(1):119-126.
32. 35S]thio)-triphosphate binding and antibody study. Mol Pharmacol 1999; 55(3):564-574.
33. 3 receptors in Chinese hamster ovary cells. J Pharmacol Exp Ther 1999; 290(2):908-916.
34. 3 receptor signaling in Chinese hamster ovary cells. Psychopharmacology (Berl) 2000; 150(4):383-390.
35. 3 dopamine receptor to G(o) subtype of G proteins in SH-SY5Y cells. Br J Pharmacol 1999; 128(6):1181-1188.
36. 3 receptor and 7-OH-DPAT. Trends Pharmacol Sci 1994; 15(6):173-174.
37. 4 dopamine receptors in fibroblast and dopaminergic cell lines. J Pharmacol Exp Ther 1994; 268(1):495-502.
38. 3 dopamine receptors in insect cells using the baculovirus system. Biochem Soc Trans 1995; 23(1):93S.
39. 2 receptor. Eur J Pharmacol 1992; 225(4):331-337.
40. 3 dopamine receptors in GH4Cl pituitary cells. FEBS Lett 1992; 312(2-3):123-126.
41. 3 receptor expressed in transfected cell lines. Eur J Pharmacol 1994; 266(1):79-85.
42. 2 dopamine receptors. Mol Pharmacol 1994; 45(1):51-60.
43. 3 dopamine receptors to G-proteins. FEBS Lett 1993; 315(3):223-226.
44. 3 receptor in a transfected NG 108-15 neuroblastoma-glioma hybrid cell line. Eur J Pharmacol 1994; 268(2):129-139.
45. 125I]R(+)trans-7-OH- PIPAT in rat brain. Naunyn Schmiedebergs Arch Pharmacol 1994; 350(6):611-617.
46. 3 receptors in rat olfactory tubercle. J Pharmacol Exp Ther 1994; 268(2):935-942.
47. 2 dopamine receptors from the high- to low-affinity state for dopamine agonists using sodium ions and guanine nucleotides. J Neurochem 1985; 44(6):1925-1935.
48. 3 receptor agonist ligand, to CHO-K1 cells. Life Sci 1995; 57(15):1401-1410.
49. 2 receptors in rat central nervous system. Neuroscience 1989; 30(3):767-777.
50. 3H]T-OH-DPAT-labeled binding sites in rat brain to inactivation by N-ethoxycarbonyl-2-ethoxy-1,2- dihydroquinoline. Brain Res 1995; 698(1-2):146-154.
51. 2 dopamine receptors by 7-OH-DPAT. Synapse 1996; 24(1):60-64.
52. 3 receptor structure. J Pharmacol Exp Ther 2000; 295(1):274-283.
53. Kebabian JW, Petzold GL, Greengard P. Dopamine sensitive adenylate cylase in caudate nucleus of rat brain, and its similarity to the dopamine receptor. Proc Natl Acad Sci USA 1972; 69(8):2145-2149.
54. DeCamilli P, Macconi D, Spada A. Dopamine inhibits adenylate cyclase in human prolactin-secreting pituitary adenomas. Nature 1979; 278(5701): 252-254.
55. 2 subfamily of dopamine receptors. Cell Signal 1996; 8(6):453-459.
56. 2 dopamine receptor expressed in CHO cells. FEBS Lett 1993; 324(1):81-86.
57. 3 receptors expressed in Chinese hamster ovary (CHO) cells. Biochem Pharmacol 1999; 58(2):285-289.
58. 3 receptor. Synapse 1995; 21(1):1-9.
59. 3 receptor: opposite and synergistic interactions with cyclic AMP. J Neurochem 1997; 68(1):1-9.
60. 3 receptor. Mol Pharmacol 1997; 52(3):508-514.
61. 2+ inhibitable adenylyl cyclase in dopaminergically innervated rat brain regions. Mol Brain Res 1994; 22(104):236-244.
62. 3 receptors. FEBS Lett 1999; 447(2-3):251-256.
63. 3 dopamine receptors. Cell Mol Neurobiol 2002; 22(1):47-56.
64. 2 receptor functionally coupled to adenylyl cyclase in Chinese hamster ovary cells. Mol Pharmacol 1995; 48(2):344-351.
65. 3 dopamine receptor heterodimers exhibit unique functional properties. J Biol Chem 2001; 276(32):30308-30314.
66. 3 dopamine receptors stably transfected into NG108-15 cells couple to a voltage-dependent potassium current via distinct G protein mechanisms. Synapse 1996; 24(2):156-164.
67. 4 dopamine receptors couple to G protein-regulated potassium channels in Xenopus oocytes. Mol Pharmacol 1996; 49(4):656-661.
68. 3 and D2L receptors couple to inward rectifier potassium channels in mammalian cell lines. Mol Cell Neurosci 1998; 12(6):390-402.
69. 3 dopamine receptor-mediated regulation of spontaneous secretory activity. J Gen Physiol 2000; 115(6):697-706.
70. 3 dopamine autoreceptors do not activate G-protein-gated inwardly rectifying potassium channel currents in substantia nigra dopamine neurons. J Neurosci 2003; 23(13):5693-5697.
71. 4 dopamine receptors. Br J Pharmacol 1994; 112(3):728-734.
72. 3 dopamine receptor inhibits P/Q-type calcium channels and secretory activity in AtT-20 cells. J Neurosci 1999; 19(5):1698-1707.
73. 3 receptors mediate mitogen-activated protein kinase activation via a phosphatidylinositol 3-kinase and an atypical protein kinase C-dependent mechanism. Mol Pharmacol 1999; 56(5):1025-1030.
74. 3 receptor and elongation factor-1Bbetagamma. Life Sci 2003; 73(23):2991-3004.
75. Abate C, Curran T. Encounters with Fos and Jun on the road to AP-1. Semin Cancer Biol 1990; 1(1):19-26.
76. Sheng M, Greenberg ME. The regulation and function of c-fos and other immediate early genes in the nervous system. Neuron 1990; 4(4):477-485.
77. 3 receptors induces c-fos expression in primary cultures of rat striatal neurons. J Neurosci Res 2000; 59(6):740-749.
78. 3 receptor functions in rat forebrain. Prog Neuropsychopharmacol Biol Psychiatry 1998; 22(5):857-882.
79. 3 receptor antisense administration reduces basal c-fos and NGFI-B mRNA levels in the rat forebrain. Synapse 1999; 32(1):51-57.
80. 3 receptors. Cereb Cortex 1996; 6(4):561-570.
81. 3 dopamine receptor antagonist, U99194A, on brain stimulation and d-amphetamine reward, motor activity, and c-fos expression in ad libitum fed and food-restricted rats. Psychopharmacology (Berl) 2002; 163(1):76-84.
82. 3 receptors in islands of Calleja and shell of nucleus accumbens of the rat: opposite and synergistic functional interactions. Eur J Neurosci 1998; 10(5):1676-1686.
83. 3 agonist, induces c-fos mRNA expression in the rat cerebellum. Jpn J Pharmacol 2002; 89(3):309-315.
84. Curran EJ, Watson SJ Jr. Dopamine receptor mRNA expression patterns by opioid peptide cells in the nucleus accumbens of the rat: a double in situ hybridization study. J Comp Neurol 1995; 361(1):57-76.
85. Surmeier DJ, Song WJ, Yan Z. Coordinated expression of dopamine receptors in neostriatal medium spiny neurons. J Neurosci 1996; 16(20):6579-6591.
86. 3 receptors. J Biol Chem 1999; 274(41):29406-29412.
87. 3 receptors have spatial working memory deficits. J Neurosci 2002; 22(13):5619-5629.
88. 2+, cAMP-responsive element binding proteins, and mitogen-activated protein kinase signaling. J Neurosci 1997; 17(19):7252-7266.
89. Ginty DD. Calcium regulation of gene expression: isn't that spatial? Neuron 1997; 18(2):183-186.
90. Ferguson SS, Downey WE III, Colapietro AM, Barak LS, Menard L, Caron MG. Role of β-arrestin in mediating agonist-promoted G protein-coupled receptor internalization. Science 1996; 271(5247):363-366.
91. 3 receptors by G protein-coupled receptor kinases and β-arrestins. J Biol Chem 2001; 276(40):37409-37414.
92. Kabbani N, Negyessy L, Lin R, Goldman-Rakic P, Levenson R. Interaction with neuronal calcium sensor NCS-1 mediates desensitization of the D2 dopamine receptor. J Neurosci 2002; 22(19):8476-8486.